ethyl vanillin
 
Notes:
Flavouring agent with flavouring power 2-4 times greater than vanillin. Used esp. in cocoa products
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas    Flavor Demo Formulas
3-ethoxy-4-hydroxybenzaldehyde (Click)
CAS Number: 121-32-4Picture of molecule
ECHA EINECS - REACH Pre-Reg: 204-464-7
FDA UNII:YC9ST449YJ
Nikkaji Web: J2.006K
Beilstein Number: 1073761
MDL: MFCD00006944
FEMA Number: 2464
CoE Number: 108
XlogP3: 1.60 (est)
Molecular Weight: 166.17630000
Formula: C9 H10 O3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: ADI: 0-3 (JECFA, 1995).
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Perfumer and Flavorist: Search
Google Patents: Search
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Pubchem Patents: Search
PubMed: Search
NCBI: Search
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
JECFA Food Flavoring: 893  ethyl vanillin
Flavis Number: 05.019 (Old)
DG SANTE Food Flavourings: 05.019  ethyl vanillin
FEMA Number: 2464  ethyl vanillin
FDA Mainterm: ETHYL VANILLIN
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.60 Synthetic flavoring substances and adjuvants.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.90 Substances migrating to food from paper and paperboard products.
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Physical Properties:
Appearance: white to off-white powder (est)
Heavey Metals: <10.00 ppm
Food Chemicals Codex Listed: Yes
Melting Point: 76.00 to  78.00 °C. @ 760.00 mm Hg
Boiling Point: 285.00 to  294.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.000880 mm/Hg @ 25.00 °C. (est)
Flash Point: 293.00 °F. TCC ( 145.00 °C. )
logP (o/w): 1.580
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 chloroform
 ethyl alcohol, 1gm. in 3cc of 95% alcohol at 32°F
 ethyl alcohol, 2 vol. 95% alcohol
 ethyl alcohol, 4.81 g. in 100ml. 80% propylene glycol/ 20% water by volume at 77
 fixed oils
 glycerin
 propylene glycol
 water, 2867 mg/L @ 25 °C (est)
 water, 2820 mg/L @ 25 °C (exp)
Insoluble in:
 paraffin oil
Stability:
 cream
 hair spray
 lipstick
 lotion
 powder
 store in cool place in sealed containers
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Organoleptic Properties:
Odor Type: vanilla
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
Odor Description:
at 10.00 % in dipropylene glycol. 
sweet creamy vanilla caramel
Substantivity: 400 Hour(s)
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
soothing agents
Synonyms   Articles   Notes   Search   Top
Safety Information:
Most important hazard(s):
Xn - Harmful.
  R 22 - Harmful if swallowed.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Oral/Parenteral Toxicity:
  gavage-rat LD50  [sex: M,F] > 2000 mg/kg
(Jenner et al., 1964)

gavage-rat LD50  [sex: M] 4470 mg/kg
(Rhône-Poulenc, Inc., 1992b)

oral-rat LD50  [sex: M,F] 3500 mg/kg
Administered as a 10% solution in corn oil.
(Monsanto Co., 1991a)

oral-rat LD50  [sex: M,F] 3500 mg/kg
Administered as a 20% solution-suspension in corn oil.
(Monsanto Co., 1991b)

gavage-rabbit LD50  2000 mg/kg
(Deichmann & Kitzmiller, 1940)

intravenous-dog LDLo  760 mg/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 238, Pg. 2576, 1954.

intraperitoneal-guinea pig LD50  1140 mg/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 238, Pg. 2576, 1954.

intraperitoneal-mouse LD50  750 mg/kg
Clinical Toxicology. Vol. 10, Pg. 61, 1977.

oral-rabbit LDLo  3000 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 425, 1940.

oral-rat LD50  1590 mg/kg
FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 39, 1967.

Dermal Toxicity:
  skin-rabbit LD50 > 7940 mg/kg
National Technical Information Service. Vol. OTS0534355

subcutaneous-rat LDLo 1800 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 425, 1940.

Inhalation Toxicity:
  Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for ethyl vanillin usage levels up to:
  8.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 5400.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 43000.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -63.00000
beverages(nonalcoholic): -20.00000
beverages(alcoholic): -100.00000
breakfast cereal: --
cheese: --
chewing gum: -110.00000
condiments / relishes: --
confectionery froastings: 140.00000200.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -47.00000
fruit ices: -47.00000
gelatins / puddings: -74.00000
granulated sugar: --
gravies: --
hard candy: -65.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
EPI System: View
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 121-32-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 8467
National Institute of Allergy and Infectious Diseases: Data
WGK Germany:1
 3-ethoxy-4-hydroxybenzaldehyde
Chemidplus: 0000121324
EPA/NOAA CAMEO:hazardous materials
RTECS: CU6125000 for cas# 121-32-4
Synonyms   Articles   Notes   Search   Top
References:
 3-ethoxy-4-hydroxybenzaldehyde
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 121-32-4
Pubchem (cid): 8467
Pubchem (sid): 134975544
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
Metabolomics Database: Search
KEGG (GenomeNet): D01086
HMDB (The Human Metabolome Database): HMDB29665
FooDB: FDB000841
YMDB (Yeast Metabolome Database): YMDB01687
Export Tariff Code: 2912.49.2600
Haz-Map: View
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 bird of paradise fragranceFR
acidic
 cyclohexyl acetic acidFL/FR
aldehydic
 acetyl nonyrylFL/FR
amber
 cistus ladaniferus resinoidFR
animal
 animal carbolactoneFR
 costus valerolactoneFR
anise
 anise seed oil colombiaFL/FR
anisic
para-acetanisoleFL/FR
ortho-anisaldehydeFL/FR
para-anisaldehydeFL/FR
 dihydroanetholFL/FR
 methyl para-anisateFL/FR
balsamic
2-acetyl furanFL/FR
sumatra benzoin absoluteFL/FR
siam benzoin absoluteFL/FR
 benzoin absolute replacerFL/FR
sumatra benzoin gumFL/FR
sumatra benzoin resinFL/FR
siam benzoin resinFL/FR
 benzoin resin replacerFR
sumatra benzoin resinoidFL/FR
siam benzoin resinoidFL/FR
1-benzoyl acetoneFL/FR
 benzyl cinnamateFL/FR
isobutyl cinnamateFL/FR
 cinnamyl alcoholFL/FR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 guaiacyl phenyl acetateFL/FR
 methyl cinnamateFL/FR
 peru balsam absoluteFL/FR
 peru balsam oilFL/FR
 peru balsam resinoidFL/FR
3-phenyl propyl alcoholFL/FR
bready
 coffee furanoneFL/FR
buttery
 acetoinFL/FR
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
 acetyl propionylFL/FR
 butyl butyryl lactateFL/FR
3,4-hexane dioneFL/FR
2-oxobutyric acidFL/FR
 caramel furanone solutionFL/FR
 caramel pentadioneFL/FR
 coffee dioneFL/FR
 cycloteneFL/FR
 cyclotene hydrateFL/FR
alpha,alpha-dimethyl anisyl acetoneFL/FR
 ethyl 2-hydroxy-2-methyl butyrateFL/FR
 ethyl cyclopentenoloneFL/FR
 ethyl furaneolFL/FR
 ethyl maltolFL/FR
5-ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-oneFL/FR
 fenugreek absoluteFL/FR
 geranyl crotonateFR
 immortelle absoluteFL/FR
 levulinic acidFL/FR
 maltolFL/FR
 maltyl propionateFL/FR
 maple furanoneFL/FR
 menthone lactoneFL/FR
 mesitene lactoneFR
5-methyl furfuralFL/FR
 rosefuranFL/FR
 shoyu furanoneFL/FR
 strawberry furanoneFL/FR
 strawberry furanone acetateFL/FR
 strawberry furanone solutionFL/FR
 toffee furanoneFL/FR
cheesy
 butyric acidFL/FR
chemical
 styralyl alcoholFL/FR
chocolate
isoamyl phenyl acetateFL/FR
 chocolate specialtyFR
citrus
blood orange oil italyFL/FR
sweet orange peel oil c.p. brazilFL/FR
coconut
alpha-angelica lactoneFL/FR
 coconut decanone methylFR
delta-decalactoneFL/FR
delta-2-dodecenolactoneFL/FR
gamma-heptalactoneFL/FR
delta-nonalactoneFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
gamma-octalactoneFL/FR
delta-undecalactoneFL/FR
coumarinic
 coumaneFL/FR
 tonka bean resinoidFR
creamy
 butyl lactateFL/FR
gamma-butyrolactoneFL/FR
 creamy lactoneFL/FR
 cyclotene propionateFL/FR
 geranyl ethyl acetalFR
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
para-vanillic acidFL/FR
para-vanillyl alcoholFL/FR
 veratraldehydeFL/FR
earthy
1-nonen-3-olFL/FR
ethereal
 ethyl 4-pentenoateFL/FR
 ethyl pyruvateFL/FR
isovaleraldehyde propylene glycol acetalFL/FR
fatty
(Z)-dairy lactoneFL/FR
 ethyl undecylenateFL/FR
4-methyl octanoic acidFL/FR
fermented
 butyl laevo-lactateFL/FR
 ethyl (E)-2-crotonateFL/FR
floral
 acetophenoneFL/FR
 coffee flower absoluteFR
para-cresyl laurateFL/FR
 cyclohexyl ethyl alcoholFL/FR
alpha-damasconeFL/FR
 dihydrojasmoneFL/FR
 dimethyl benzyl carbinyl butyrateFL/FR
 ethyl phenyl acetateFL/FR
 floral pyranolFR
 heliotropinFL/FR
 heliotropyl acetateFL/FR
 heliotropyl acetoneFL/FR
 heliotropyl diethyl acetalFR
 hyacinth etherFR
para-methyl acetophenoneFL/FR
 methyl dihydrojasmonateFL/FR
beta-naphthyl methyl ketoneFL/FR
 nerolidolFL/FR
 peony alcoholFR
 phenethyl acetateFL/FR
 phenethyl alcoholFL/FR
 phenethyl isobutyrateFL/FR
 phenethyl phenyl acetateFL/FR
 rose butanoateFL/FR
 violet methyl carbonateFR
fruity
 acetoin acetateFL/FR
para-anisyl propionateFL/FR
 artemisia pallens herb oilFL/FR
beta-damasconeFL/FR
gamma-decalactoneFL/FR
 ethyl methyl-para-tolyl glycidateFL/FR
(E)-ethyl tiglateFL/FR
 farnesyl acetoneFL/FR
 guaiacyl propionateFL/FR
 methyl (Z)-5-octenoateFL/FR
 octyl butyrateFL/FR
 raspberry ketoneFL/FR
 raspberry ketone acetateFL/FR
 raspberry ketone methyl etherFL/FR
 tetrahydrofurfuryl acetateFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
 vanilla carboxylateFL/FR
green
isoamyl 3-(2-furan) propionateFL/FR
isobutyl benzyl carbinolFL/FR
(Z)-4-hepten-1-olFL/FR
(Z)-4-heptenalFL/FR
(Z)-4-heptenal diethyl acetalFL/FR
(Z)-3-hexen-1-yl propionateFL/FR
 hexyl 2-methyl butyrateFL/FR
 violet leaf absoluteFL/FR
hay
 beeswax absoluteFL/FR
 hay absoluteFR
herbal
 butyl levulinateFL/FR
honey
 methyl phenyl acetateFL/FR
 phenyl acetic acidFL/FR
licorice
(E)-anetholFL/FR
melon
(Z)-6-nonenalFL/FR
 watermelon ketoneFR
milky
laevo-glutamineCS
minty
laevo-carvoneFL/FR
 menthoxypropane diolFL/FR
 vanillin menthoxypropane diol acetalFL/FR
mossy
 veramoss (IFF)FR
mushroom
3-octen-2-olFL/FR
musk
 ethylene brassylateFL/FR
omega-pentadecalactoneFL/FR
musty
3-acetyl-2,5-dimethyl furanFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
para-methyl anisoleFL/FR
beta-naphthyl ethyl etherFL/FR
nutty
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
2,3-dimethyl pyrazineFL/FR
 nutty cyclohexenoneFL/FR
 resorcinolFR
2,3,5,6-tetramethyl pyrazineFL/FR
phenolic
 ethyl vanillateFL/FR
ortho-guaiacolFL/FR
4-methyl-2,6-dimethoxyphenolFL/FR
 vanillyl ethyl etherFL/FR
popcorn
2-acetyl pyrazineFL/FR
powdery
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
2,6-dimethoxyphenolFL/FR
alpha-ethoxy-ortho-cresolFL/FR
spicy
 allspice oilFL/FR
para-anisyl formateFL/FR
 benzyl isoeugenolFL/FR
 cassia bark oil chinaFL/FR
 clove bud oilFL/FR
 dianthus ethoneFR
4-ethyl guaiacolFL/FR
isoeugenyl acetateFL/FR
para-methoxycinnamaldehydeFL/FR
(E)-para-methoxycinnamaldehydeFL/FR
alpha-methyl cinnamaldehydeFL/FR
4-methyl guaiacolFL/FR
 methyl isoeugenolFL/FR
cis-oak lactone 
 spicy acetoacetateFL/FR
 zingeroneFL/FR
sweet
 tonka bean absolute replacerFR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla bean absolute (vanilla spp.)FL/FR
 vanilla bean aromatica 
 vanilla bean planifoliaCS
 vanilla oleoresin baliFL/FR
 vanilla oleoresin bourbonFL/FR
 vanilla resinoidFL/FR
 vanilla tahitensis fruit absoluteFR
 vanilla tahitensis fruit absolute CO2 extractFR
 vanilla tahitensis fruit extractFL/FR
 vanilla tahitensis fruit oil CO2 extractFR
tonka
6-amyl-alpha-pyroneFL/FR
 coumarinFR
gamma-hexalactoneFL/FR
 mint lactoneFL/FR
 octahydrocoumarinFL/FR
 tonka bean absoluteFR
tropical
 curcuma amada roxb. rhizome oil CO2 extractFL/FR
vanilla
 acetovanilloneFL/FR
 benzoinFL/FR
 crème brulee fragranceFR
ortho-dimethyl hydroquinoneFL/FR
 ethyl vanillin acetateFR
 ethyl vanillin diethyl acetalFR
 ethyl vanillin hexylene glycol acetalFR
 ethyl vanillin isobutyrateFL/FR
 ethyl vanillin propylene glycol acetalFL/FR
 heliotropyl alcoholFL/FR
 methyl vanillateFL/FR
 propenyl guaetholFL/FR
isopropyl vanillin 
 vanillaFR
 vanilla aromatica fruit extractFL/FR
 vanilla bean absolute CO2 extract (vanilla planifolia)FL/FR
 vanilla bean fragranceFR
 vanilla bean oil (vanilla planifolia)FR
 vanilla bean oil (vanilla tahitensis)FL/FR
 vanilla bean oil CO2 extractFL/FR
 vanilla bean tahitensisCS
 vanilla bean tinctureFR
 vanilla cresolFR
 vanilla extractFL/FR
 vanilla fragranceFR
country vanilla fragranceFR
french vanilla fragranceFR
 vanilla planifolia fruit extractFL/FR
 vanilla planifolia fruit infusionFR
 vanilla planifolia fruit waterFL/FR
 vanilla specialtyFR
 vanillinFL/FR
 vanillin 2,3-butylene glycol acetalFL/FR
 vanillin hexylene glycol acetalFR
 vanillin propylene glycol acetalFL/FR
 vanillyl acetateFL/FR
 vanillyl butyl etherFL/FR
 vanillyl isobutyrateFL/FR
 vanillylidene acetoneFL/FR
vegetable
 methionalFL/FR
 tetrahydrofurfuryl alcoholFL/FR
waxy
 allyl nonanoateFL/FR
 ethyl palmitateFL/FR
 methyl laurateFL/FR
2-nonanolFL/FR
 octyl isobutyrateFL/FR
delta-tetradecalactoneFL/FR
 undecanoic acidFL/FR
woody
 guaiacwood extract acetateFR
 guaiacwood oilFL/FR
 guaiacyl acetateFL/FR
 gurjun balsam oilFR
4-hydroxybenzaldehydeFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 sandal pentanolFR
 santallFR
 tobacarol (IFF)FR
 vetiver oil haitiFL/FR
 
For Flavor
 
No flavor group found for these
2-acetyl-3,4,5,6-tetrahydropyridineFL
 allyl 2-furoateFL
 allyl methyl trisulfideFL
para-anisyl propionateFL/FR
 benzoinFL/FR
1-benzoyl acetoneFL/FR
 benzyl disulfideFL
 coumaneFL/FR
 cyclotene propionateFL/FR
6-decenoic acidFL
2,5-diethyl tetrahydrofuranFL
alpha,alpha-dimethyl anisyl acetoneFL/FR
ortho-dimethyl hydroquinoneFL/FR
delta-2-dodecenolactoneFL/FR
alpha-ethoxy-ortho-cresolFL/FR
 ethyl 2-hydroxy-2-methyl butyrateFL/FR
 ethyl 4-pentenoateFL/FR
 ethyl vanillateFL/FR
5-ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-oneFL/FR
 farnesyl acetoneFL/FR
 furfuryl acetoneFL
3-(2-furyl) acroleinFL
 glucoethyl vanillinFL
 glucovanillinFL
 guaiacyl propionateFL/FR
 heliotropyl alcoholFL/FR
 heptanal 2,3-butane diol acetalFL
 mango furanoneFL
 menthone lactoneFL/FR
 menthoxypropane diolFL/FR
(E)-para-methoxycinnamaldehydeFL/FR
4-methoxysalicylaldehydeFL
 methyl para-anisateFL/FR
 methyl vanillateFL/FR
cis-oak lactone 
 peru balsamFL
isopropyl vanillin 
 rosefuranFL/FR
 toffee furanoneFL/FR
 vanillin menthoxypropane diol acetalFL/FR
 vanillyl butyl etherFL/FR
 vanillyl ethyl etherFL/FR
 vanilmandelic acidFL
isoamyl 3-(2-furan) propionateFL/FR
beta-damasconeFL/FR
acidic
 levulinic acidFL/FR
aldehydic
 acetyl nonyrylFL/FR
amber
isobutyl benzyl carbinolFL/FR
anise
(E)-anetholFL/FR
 anise seed oil colombiaFL/FR
anisic
para-acetanisoleFL/FR
ortho-anisaldehydeFL/FR
aromatic
 benzyl isoeugenolFL/FR
balsamic
 benzoin absolute replacerFL/FR
sumatra benzoin gumFL/FR
sumatra benzoin resinFL/FR
siam benzoin resinFL/FR
sumatra benzoin resinoidFL/FR
siam benzoin resinoidFL/FR
isobutyl cinnamateFL/FR
 ethyl cinnamateFL/FR
 peru balsam absoluteFL/FR
 peru balsam oilFL/FR
 peru balsam resinoidFL/FR
 vanillylidene acetoneFL/FR
berry
 heliotropyl acetoneFL/FR
 raspberry ketone acetateFL/FR
 raspberry ketone methyl etherFL/FR
bready
2-propionyl thiazoleFL
brown
 beeswax absoluteFL/FR
2-oxobutyric acidFL/FR
5-methyl furfuralFL/FR
 tetrahydrofurfuryl acetateFL/FR
burnt
 furfuryl alcoholFL
buttery
 butter cream frosting flavorFL
 butter nut vanilla flavorFL
 butter vanilla nut flavorFL
 butyl laevo-lactateFL/FR
 diacetylFL
3,4-hexane dioneFL/FR
delta-tetradecalactoneFL/FR
cabbage
 methyl 2-thiofuroateFL
caramellic
 caramel furanoneFL
 caramel furanone solutionFL/FR
 caramel malted mambo flavorFL
 caramel pentadioneFL/FR
 creme brulee flavorFL
 cycloteneFL/FR
 cyclotene hydrateFL/FR
 ethyl furaneolFL/FR
 ethyl maltolFL/FR
5-ethyl-3,4,5,6-tetramethyl cyclohexen-2-oneFL
 fenugreek absoluteFL/FR
 lucuma flavorFL
 maltolFL/FR
 maltyl propionateFL/FR
 maple cream flavorFL
 maple furanoneFL/FR
3-methyl butyl 2-furyl butyrateFL
 pyruvaldehydeFL
 shoyu furanoneFL/FR
 strawberry furanoneFL/FR
 strawberry furanone acetateFL/FR
 strawberry furanone solutionFL/FR
chemical
 styralyl alcoholFL/FR
cherry
 heliotropinFL/FR
para-methoxycinnamaldehydeFL/FR
citrus
beta-naphthyl methyl ketoneFL/FR
blood orange oil italyFL/FR
sweet orange peel oil c.p. brazilFL/FR
coconut
delta-decalactoneFL/FR
(R)-massoia lactoneFL
6-methyl coumarinFL
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
 octahydrocoumarinFL/FR
coffee
 coffee creme brulee flavorFL
 coffee dioneFL/FR
2-thiophene thiolFL
corn chip
2-acetyl-2-thiazolineFL
creamy
 acetoinFL/FR
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
6-amyl-alpha-pyroneFL/FR
alpha-angelica lactoneFL/FR
para-anisaldehydeFL/FR
 butyl butyryl lactateFL/FR
 creamy lactoneFL/FR
 dihydrocoumarinFL
 divanillinFL
gamma-hexalactoneFL/FR
4-hydroxybenzaldehydeFL/FR
para-methyl acetophenoneFL/FR
 mint lactoneFL/FR
delta-nonalactoneFL/FR
 octyl isobutyrateFL/FR
delta-undecalactoneFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
para-vanillic acidFL/FR
para-vanillyl alcoholFL/FR
 veratraldehydeFL/FR
dairy
 butyl lactateFL/FR
 creme brulle coffee flavorFL
 methyl (Z)-5-octenoateFL/FR
earthy
1-nonen-3-olFL/FR
eggy
 egg nog creme brulee flavorFL
fatty
(Z)-dairy lactoneFL/FR
 diacetyl trimerFL
 ethyl undecylenateFL/FR
4-methyl octanoic acidFL/FR
2,4-octadien-1-olFL
(E,E)-2,4-undecadienalFL
2,4-undecadienalFL
floral
isoamyl phenyl acetateFL/FR
 dihydrojasmoneFL/FR
 dimethyl benzyl carbinyl butyrateFL/FR
 heliotropyl acetateFL/FR
 methyl dihydrojasmonateFL/FR
 methyl phenyl acetateFL/FR
 phenethyl alcoholFL/FR
 phenyl acetic acidFL/FR
fruity
 acetoin acetateFL/FR
 acetyl isovalerylFL
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
 artemisia pallens herb oilFL/FR
alpha-damasconeFL/FR
gamma-decalactoneFL/FR
 ethyl 3-oxohexanoateFL
 ethyl methyl-para-tolyl glycidateFL/FR
(E)-ethyl tiglateFL/FR
 furfuryl valerateFL
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
(E,E)-methyl sorbateFL
2-pentanoyl furanFL
 raspberry ketoneFL/FR
 rose butanoateFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
isovaleraldehyde propylene glycol acetalFL/FR
 vanilla carboxylateFL/FR
green
 cinnamyl alcoholFL/FR
 cyclohexyl ethyl alcoholFL/FR
(Z)-4-hepten-1-olFL/FR
(Z)-4-heptenalFL/FR
(Z)-4-heptenal diethyl acetalFL/FR
(Z)-3-hexen-1-yl propionateFL/FR
 hexyl 2-methyl butyrateFL/FR
 immortelle absoluteFL/FR
 nerolidolFL/FR
(Z)-6-nonenalFL/FR
 violet leaf absoluteFL/FR
herbal
 butyl levulinateFL/FR
 dihydroanetholFL/FR
5-hydroxymethyl furfuralFL
honey
 ethyl phenyl acetateFL/FR
 phenethyl acetateFL/FR
 phenethyl isobutyrateFL/FR
 phenethyl phenyl acetateFL/FR
jammy
 ethyl cyclopentenoloneFL/FR
lactonic
gamma-heptalactoneFL/FR
gamma-octalactoneFL/FR
meaty
4-allyl-2,6-dimethoxyphenolFL
medicinal
2,6-dimethoxyphenolFL/FR
milky
gamma-butyrolactoneFL/FR
minty
laevo-carvoneFL/FR
mushroom
3-octen-2-olFL/FR
musk
 ethylene brassylateFL/FR
musty
2,3-dimethyl pyrazineFL/FR
 ethyl (E)-2-crotonateFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
para-methyl anisoleFL/FR
nutty
2-acetyl furanFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
 coffee furanoneFL/FR
 furfural acetoneFL
 nutty cyclohexenoneFL/FR
 peanut oxazoleFL
 tetrahydrofurfuryl alcoholFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
phenolic
 guaiacyl phenyl acetateFL/FR
4-methyl-2,6-dimethoxyphenolFL/FR
powdery
 acetophenoneFL/FR
beta-naphthyl ethyl etherFL/FR
 powdery ketoneFL
roasted
2-acetyl pyrazineFL/FR
rummy
 ethyl pyruvateFL/FR
sour
 butyric acidFL/FR
spicy
 allspice oilFL/FR
para-anisyl formateFL/FR
siam benzoin absoluteFL/FR
sumatra benzoin absoluteFL/FR
 benzyl cinnamateFL/FR
 benzylidene acetoneFL
 cassia bark oil chinaFL/FR
 clove bud oilFL/FR
isoeugenyl acetateFL/FR
alpha-methyl cinnamaldehydeFL/FR
 methyl cinnamateFL/FR
 methyl isoeugenolFL/FR
3-phenyl propyl alcoholFL/FR
 root beer float flavorFL
 spicy acetoacetateFL/FR
chai vanilla flavorFL
 zingeroneFL/FR
sweet
 caramel dioneFL
 cyclohexyl acetic acidFL/FR
 ethyl 3-(2-hydroxyphenyl) propionateFL
 molasses flavorFL
 orange vanilla cream flavorFL
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla bean absolute (vanilla spp.)FL/FR
 vanilla bean aromatica 
 vanilla butter nut flavorFL
 vanilla concentrateFL
 vanilla oleoresin baliFL/FR
 vanilla oleoresin bourbonFL/FR
 vanilla resinoidFL/FR
 vanilla tahitensis fruit extractFL/FR
toasted
 acetyl propionylFL/FR
tomato
 methionalFL/FR
tropical
 curcuma amada roxb. rhizome oil CO2 extractFL/FR
vanilla
 acetovanilloneFL/FR
vanilla chai flavorFL
 ethyl vanillin isobutyrateFL/FR
 ethyl vanillin propylene glycol acetalFL/FR
vanilla ice cream flavorFL
4-methyl guaiacolFL/FR
omega-pentadecalactoneFL/FR
 propenyl guaetholFL/FR
 vanilla aromatica fruit extractFL/FR
 vanilla bean absolute CO2 extract (vanilla planifolia)FL/FR
 vanilla bean flavor keyFL
 vanilla bean oil (vanilla tahitensis)FL/FR
 vanilla bean oil CO2 extractFL/FR
 vanilla bean pasteFL
 vanilla bean powderFL
 vanilla distillatesFL
 vanilla extractFL/FR
 vanilla flavorFL
french vanilla flavorFL
bakers white vanilla flavorFL
bourbon vanilla flavorFL
 vanilla flavor keyFL
 vanilla hazelnut flavorFL
 vanilla macadamia nut flavorFL
 vanilla nut creme flavorFL
 vanilla pandan flavorFL
 vanilla planifolia fruit extractFL/FR
 vanilla planifolia fruit waterFL/FR
 vanilla powder flavorFL
 vanilla swirl flavorFL
 vanillinFL/FR
 vanillin 2,3-butylene glycol acetalFL/FR
 vanillin propylene glycol acetalFL/FR
 vanillyl acetateFL/FR
 vanillyl isobutyrateFL/FR
waxy
 allyl nonanoateFL/FR
para-cresyl laurateFL/FR
 ethyl palmitateFL/FR
 furfuryl octanoateFL
 methyl laurateFL/FR
2-nonanolFL/FR
 octyl 2-furoateFL
 octyl butyrateFL/FR
 undecanoic acidFL/FR
woody
4-ethyl guaiacolFL/FR
ortho-guaiacolFL/FR
 guaiacwood oilFL/FR
 guaiacyl acetateFL/FR
 patchouli oilFL/FR
 vetiver oil haitiFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 acacia cassie farnesianaFR
 acorn 
 allspiceFR
 almond blossom 
 amberFR
 appleFR
 apple greenFR
 apricotFR
 azaleaFR
 baby powderFR
 balsamFR
 bananaFR
 barleyFL
 bay rumFR
 bayberryFR
 bean locust bean 
 benzoin 
 blackberryFR
 blueberryFR
 bouquetFR
 bread bakedFR
 bubble gumFR
 butter rum 
 butterscotchFR
 cabreuvaFR
 cakeFL
 candy 
 cappuccinoFL
 caramelFL
 carnation dianthus oeilletFR
 cassiaFR
 cassia blossom 
 castoreumFR
 cedarFR
 cedarwoodFR
 cherry blossomFR
 chocolate cocoa 
 christmas blendsFR
 cloveFR
 clove blossom 
 coconutFR
 coffeeFR
 coloniaFR
 cookie 
 cotton candyFR
 crabapple blossomFR
 creamFR
 cream ice cream 
 cream sodaFL
 custardFL
 dateFR
 egg nogFL
 elder berryFR
 elder flowerFR
 fagoniaFR
 fenugreekFL/FR
 figFR
 fir balsamFR
 floralFR
 flouveFR
 flouve blossom 
 frangipanni plumeriaFR
 fruit dried fruit 
 gardeniaFR
 genet genista broomFR
 gingerbreadFR
 gooseberryFR
 graham crackerFR
 guaiacwoodFL/FR
 gurjunFR
 habubaFR
 hawthornFR
 hay new mown hay foin coupeFR
 heliotropeFR
 hibiscusFR
 honeysuckle chevrefeuilleFR
 hyacinth jacintheFR
 hydrangeaFR
 incenseFR
 jackfruitFL
 kewda 
 labdanumFL/FR
 licoriceFR
 lilac lilas syringaFR
 lycheeFR
 maltFR
 mango flowerFR
 mapleFR
 marigold tageteFL/FR
 marshmallowFL
 meadow countryFR
 melon watermelon muskmelon cantaloupe 
 milk malted milk 
 mintFR
 molassesFL
 muskFR
 myrtleFL/FR
 oakmoss mousse de chene mossFR
 opoponaxFL/FR
 orange blossomFR
 orientalFR
 papayaFR
 passion blossomFR
 passion fruitFR
 peach blossomFR
 pearFR
 pear blossomFR
 peru balsamFL/FR
 petuniaFR
 plumFR
 plum blossom 
 plum mirabille blossom 
 poppy redFR
 powderFR
 pralineFL
 pruneFR
 pumpkin pieFR
 raisinFR
 raspberryFR
 raspberry blackFR
 redwood 
 root beerFR
 rose dog roseFR
 rose mossFR
 rum butter rum 
 sandalwoodFR
 sarsaparillaFL
 sassafrasFR
 spiceFR
 stephanotisFR
 stock evening scentedFR
 straw 
 strawberryFR
 sweet peaFR
 tabu 
 tobaccoFR
 toffeeFR
 tolu balsamFL/FR
 tonka beanFR
 valerianFL/FR
 vanillaFR
 violetFR
 wallflowerFR
 woodyFR
 wormseed chenopodiumFL
 zibeline 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
 bourbonal
 ethavan
 ethovan
3-ethoxy protocatechualdehyde
2-ethoxy-4-formyl phenol
3-ethoxy-4-hydroxy-benzaldehyde
3-ethoxy-4-hydroxybenzaldehyde
3-ethoxy-4-oxidanyl-benzaldehyde
3-ethoxyprotocatechualdehyde
 ethyl protal
 ethyl protocatechualdehyde-3-ethyl ether
 ethyl protocatechuic aldehyde
 ethyl vanillin 10% dpg
 ethyl vanillin FCC
 ethyl vanillin N.F.
 ethyl vanillin NF
 ethyl vanillin synthetic
 ethylprotal
 ethylprotocatechualdehyde-3-ethyl ether
 ethylprotocatechuic aldehyde
 ethylvanillin
4-hydroxy-3-ethoxybenzaldehyde
 protocatechuic aldehyde ethyl ether
 quantrovanil
 rhodiarome
 rhodiascent
 vanillin, ethyl-
 vanirome
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Determination of flavor enhancers in milk powder by one-step sample preparation and two-dimensional liquid chromatography.
J-Stage: Antioxidant Properties of Ethyl Vanillin in Vitro and in Vivo
PubMed: Laccase catalyzed synthesis of iodinated phenolic compounds with antifungal activity.
PubMed: A vanillin derivative causes mitochondrial dysfunction and triggers oxidative stress in Cryptococcus neoformans.
PubMed: Determination of vanillin, ethyl vanillin, and coumarin in infant formula by liquid chromatography-quadrupole linear ion trap mass spectrometry.
PubMed: The missense of smell: functional variability in the human odorant receptor repertoire.
PubMed: Oxidative decarboxylation of mandelic acid derivative by recombinant Escherichia coli: a novel method of ethyl vanillin synthesis.
PubMed: A systematic approach for optimizing the robustness of pulse sequence elements with respect to couplings, offsets, and B1-field inhomogeneities (COB).
PubMed: Phenolic compounds in particles of mainstream waterpipe smoke.
PubMed: Thermal tolerance and survival of Cronobacter sakazakii in powdered infant formula supplemented with vanillin, ethyl vanillin, and vanillic acid.
PubMed: Effect of vanillin and ethyl vanillin on cytochrome P450 activity in vitro and in vivo.
PubMed: Molecularly imprinted photonic hydrogels as colorimetric sensors for rapid and label-free detection of vanillin.
PubMed: Effect of vanillin, ethyl vanillin, and vanillic acid on the growth and heat resistance of Cronobacter species.
PubMed: Antioxidant properties of ethyl vanillin in vitro and in vivo.
PubMed: Differential presence of anthropogenic compounds dissolved in the marine waters of Puget Sound, WA and Barkley Sound, BC.
PubMed: Simultaneous spectrophotometric kinetic determination of four flavor enhancers in foods with the aid of chemometrics.
PubMed: A comprehensive evaluation of the toxicology of cigarette ingredients: aromatic carbonyl compounds.
PubMed: Synthesis and anticancer activity of some novel tetralin-6-yl-pyrazoline, 2-thioxopyrimidine, 2-oxopyridine, 2-thioxo-pyridine and 2-iminopyridine derivatives.
PubMed: [Studies on the chemical constituents of marine sponge Iotrochota sp].
PubMed: Conformational equilibria in vanillin and ethylvanillin.
PubMed: Assessment of the anti-angiogenic, anti-inflammatory and antinociceptive properties of ethyl vanillin.
PubMed: Microencapsulation of flavors in carnauba wax.
PubMed: Fast single run of vanilla fingerprint markers on microfluidic-electrochemistry chip for confirmation of common frauds.
PubMed: Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice.
PubMed: Rapid method for the determination of coumarin, vanillin, and ethyl vanillin in vanilla extract by reversed-phase liquid chromatography with ultraviolet detection.
PubMed: Dihydroagarofuranoid sesquiterpenes, a lignan derivative, a benzenoid, and antitubercular constituents from the stem of Microtropis japonica.
PubMed: Competitive and noncompetitive odorant interactions in the early neural coding of odorant mixtures.
PubMed: 3-Eth-oxy-4-hydroxy-benzaldehyde.
PubMed: Synthesis and non-aqueous medium titrations of some new 4-benzylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives.
PubMed: Rapid sample screening method for authenticity controlling vanilla flavors using a CE microchip approach with electrochemical detection.
PubMed: Optical recording of the intrinsic signal from the human olfactory cleft.
PubMed: Determination of coumarin, vanillin, and ethyl vanillin in vanilla extract products: liquid chromatography mass spectrometry method development and validation studies.
PubMed: Electrophysiological and behavioral responses to chocolate volatiles in both sexes of the pyralid moths Ephestia cautella and Plodia interpunctella.
PubMed: Qualitative determination of false-positive effects in the acetylcholinesterase assay using thin layer chromatography.
PubMed: Optimum methamphetamine profiling with sample preparation by solid-phase microextraction.
PubMed: Identification of impurities and statistical classification of methamphetamine tablets (Ya-Ba) seized in Thailand.
PubMed: Human potency predictions for aldehydes using the local lymph node assay.
PubMed: Liquid chromatographic determination of vanillin and related aromatic compounds.
PubMed: Odor response properties of rat olfactory receptor neurons.
PubMed: Identification of coumarin as the sensitizer in a patient sensitive to her own perfume but negative to the fragrance mix.
PubMed: Odorants selectively activate distinct G protein subtypes in olfactory cilia.
PubMed: Specificity of signal molecules in the activation of Agrobacterium virulence gene expression.
PubMed: Determination of coumarin as an adulterant in vanilla flavoring products by high-performance liquid chromatography.
PubMed: Identification of urinary 3-ethoxy-4-hydroxybenzoic and 3-ethoxy-4-hydroxymandelic acids after dietary intake of ethyl vanillin.
PubMed: Immediate reactions to balsam of Peru, cassia oil and ethyl vanillin.
PubMed: Determination of vanillin and ethyl vanillin in food products.
PubMed: [On the polarographic and oscillopolarographic determination of the semicarbazones of vanillin and ethyl vanillin (IV)].
PubMed: Anti-tuberculosis agents derived from 3-ethoxy-4-hydroxybenzaldehyde.
PubMed: [Differential subject for the correction of vanillin and ethyl vanillin].
Synonyms   Articles   Notes   Search   Top
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