EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

6-methyl coumarin
6-methylcoumarin

Supplier Sponsors

Flavor Demo Formulas
Name:6-methylchromen-2-one
CAS Number: 92-48-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:202-158-8
FDA UNII:EHP8W0L01A
Nikkaji Web:J3.219K
Beilstein Number:0004222
MDL:MFCD00006875
CoE Number:579
XlogP3:1.80 (est)
Molecular Weight:160.17216000
Formula:C10 H8 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1172 6-methylcoumarin
FLAVIS Number:13.012 (Old)
DG SANTE Food Flavourings:13.012 6-methylcoumarin
FEMA Number:2699 6-methylcoumarin
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):92-48-8 ; 6-METHYLCOUMARIN
 
Physical Properties:
Appearance:white crystals (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 73.00 to 79.00 °C. @ 760.00 mm Hg
Boiling Point: 303.00 °C. @ 725.00 mm Hg
Congealing Point:73.50 °C.
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 1.933 (est)
Soluble in:
 alcohol
 water, very slightly
 water, 1189 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 non-discoloring in most media
 
Organoleptic Properties:
Odor Type: coconut
Odor Strength:low ,
recommend smelling in a 1.00 % solution or less
sweet coconut vanilla creamy powdery floral
Odor Description:at 1.00 % in dipropylene glycol. sweet coconut vanilla creamy powdery floral
sweet coconut vanilla creamy powdery floral
Odor Description:Sweet coconut, vanilla, creamy with a powdery floral nuance
Mosciano, Gerard P&F 16, No. 3, 79, (1991)
Flavor Type: coconut
sweet coconut vanilla creamy
Taste Description: at 20.00 ppm. Sweet coconut, vanilla like with a creamy cake-like nuance
Mosciano, Gerard P&F 16, No. 3, 79, (1991)
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
oral care agents
 
Suppliers:
Advanced Biotech
6 METHYL COUMARIN SYNTHETIC
99% min.
Odor: Coconut, Herbaceous
Anhui Haibei
6-Methyl Coumarin
Aroma Aromatics & Flavours
6-Methyl Coumarin
Flavor: Dry herbaceous coconut
It is one of the most important constituent of coconut flavours. It is also used effectively in nut, caramel, butter, date, fig, root beer etc. Frequently used in various vanilla compositions. Its extra ordinary stability towards heat makes it excellent for flavour meant for baked goods. The concentration in finished products is usually less then 30 ppm.
Augustus Oils
6 Methyl Coumarin
Services
Berjé
6-Methyl Coumarin
Happening at Berje
BOC Sciences
For experimental / research use only.
6-Methylcoumarin
Charkit Chemical
METHYL COUMARIN, 6-
Diffusions Aromatiques
6-METHYLCOUMARINE
Elan Inc.
6-METHYLCOUMARIN
Kosher
Ernesto Ventós
6-METHYLCOUMARIN
Odor: CREAMY, COCONUT
Flavor: ALMOST BITTER, SWEET AT LOWER LEVEL
H. Interdonati, Inc.
6-Methylcoumarin Kosher
Featured Products
Indukern F&F
6-METHYL COUMARIN
Odor: SWEET, COCONUT, CREAMY
Jiangyin Healthway
6-Methyl Coumarin
New functional food ingredients
Jiangyin Healthway
6-Methylcoumarin
Kunshan Sainty
6-Methyl Coumarin, Kosher
Lluch Essence
6-METHYL COUMARIN
M&U International
6-Methyl Coumarin, Kosher
Moellhausen
6-METHYL COUMARIN
Odor: sweet, aromatic
Flavor: sweet, cocoa, vanilla
Pearlchem Corporation
6-Methyl Coumarin
Penta International
6-METHYLCOUMARIN CRYSTAL
Penta International
6-METHYLCOUMARIN POWDER
PerfumersWorld
6-Methyl Coumarin 10% in DPG
PerfumersWorld
6-Methyl Coumarin
Odor: vanilla coconut tonka-bean sweet aromatic
Phoenix Aromas & Essential Oils
Methyl-6 Coumarin
R C Treatt & Co Ltd
6-Methylcoumarin
Reincke & Fichtner
6-Methylcoumarin
Sigma-Aldrich
6-Methylcoumarin, ≥99%, FCC, FG
Odor: anise; coconut; creamy; herbaceous; vanilla; balsamic
Certified Food Grade Products
Sunaux International
6-Methyl Coumarin
TCI AMERICA
For experimental / research use only.
6-Methylcoumarin >99.0%(GC)
United International
6-Methylcoumarin
Vigon International
Methyl-6 Coumarin
Odor: COCONUT-LIKE
WholeChem
6-Methyl coumarin
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
R 42/43 - May cause sensitization by inhalation and skin contact.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 1680 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 605, 1976.

Dermal Toxicity:
subcutaneous-mouse LD50 253 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakugaku Zasshi. Journal of Pharmacy. Vol. 76, Pg. 186, 1956.

skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 605, 1976.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
IFRA Critical Effect: Photoallergy
IFRA: View Standard
Recommendation for 6-methyl coumarin usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 250.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 96.00 (μg/capita/day)
NOEL (No Observed Effect Level): 150.00 (mg/kg bw per day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -24.00000
beverages(nonalcoholic): -5.20000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: 0.8000015.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -4.80000
fruit ices: -4.80000
gelatins / puddings: -39.00000
granulated sugar: --
gravies: --
hard candy: -21.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 217: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones[1]
View page or View pdf

Flavouring Group Evaluation 80, Revision 1 (FGE.80Rev1): Consideration of alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by JECFA (61st meeting) structurally related to a aromatic lactone evaluated by EFSA in FGE.27 (2008)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for a,-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for a,-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones
View page or View pdf

EPI System: View
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):92-48-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7092
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
6-methylchromen-2-one
Chemidplus:0000092488
EPA/NOAA CAMEO:hazardous materials
RTECS:GN7792000 for cas# 92-48-8
 
References:
 6-methylchromen-2-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:92-48-8
Pubchem (cid):7092
Pubchem (sid):134972192
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB32394
FooDB:FDB009822
Export Tariff Code:2932.20.0500
Haz-Map:View
ChemSpider:View
 
Potential Blenders and core components note
For Odor
aldehydic
acetyl nonyryl
FL/FR
animal
costus valerolactone
FR
6-
methyl quinoline
FL/FR
anisic
para-
acetanisole
FL/FR
para-
anisaldehyde
FL/FR
balsamic
benzyl cinnamate
FL/FR
pine needle absolute
FL/FR
black
poplar bud oleoresin
FL/FR
buttery
acetoin
FL/FR
acetyl butyryl
FL/FR
acetyl isobutyryl
FL/FR
acetyl propionyl
FL/FR
butyl butyryl lactate
FL/FR
caramellic
2-oxo
butyric acid
FL/FR
fenugreek absolute
FL/FR
immortelle absolute
FL/FR
levulinic acid
FL/FR
strawberry furanone acetate
FL/FR
cheesy
butyric acid
FL/FR
2-
heptanone
FL/FR
chocolate
vanillyl ethyl ether
FL/FR
citrus
lime oil expressed florida
FL/FR
coconut
alpha-
angelica lactone
FL/FR
coconut decanone methyl
FR
coconut naphthalenone
FL/FR
delta-
decalactone
FL/FR
delta-2-
dodecenolactone
FL/FR
gamma-
heptalactone
FL/FR
delta-
heptalactone
FL/FR
delta-
nonalactone
FL/FR
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
gamma-
octalactone
FL/FR
delta-
octalactone
FL/FR
propyl octanoate
FL/FR
tetrahydrojasmone
FR
delta-
undecalactone
FL/FR
wine lactone
FL/FR
coumarinic
coumane
FL/FR
phthalide
FL/FR
tonka furanone
FL/FR
tonka ketone
FR
tonkavert
FR
creamy
butyl lactate
FL/FR
gamma-
butyrolactone
FL/FR
creamy lactone
FL/FR
3-
heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR
para-
vanillic acid
FL/FR
para-
vanillyl alcohol
FL/FR
earthy
1-
nonen-3-ol
FL/FR
fatty
(Z)-
dairy lactone
FL/FR
ethyl undecylenate
FL/FR
lauric acid
FL/FR
4-
methyl octanoic acid
FL/FR
fermented
butyl laevo-lactate
FL/FR
floral
para-
anisyl nitrile
FR
dihydrojasmone lactone
FL/FR
dimethyl anthranilate
FL/FR
heliotropin
FL/FR
hexenyl cyclopentanone
FR
(E)-beta-
ionone
FL/FR
jasmin lactone (IFF)
FL/FR
para-
methyl acetophenone
FL/FR
alpha-iso
methyl ionone (50% min.)
FL/FR
orris rhizome resinoid (iris pallida)
FL/FR
2-
pentyl cyclopentanone
FR
petitgrain mandarin oil terpeneless
FL/FR
rhodinyl acetate
FL/FR
fruity
acetoin acetate
FL/FR
bitter
almond oil
FL/FR
amyl heptanoate
FL/FR
iso
amyl octanoate
FL/FR
cherry propanol
FL/FR
gamma-
decalactone
FL/FR
farnesyl acetone
FL/FR
4-
hydroxybenzyl alcohol
FL/FR
methyl (Z)-5-octenoate
FL/FR
octyl butyrate
FL/FR
iso
propyl octanoate
FL/FR
tolualdehydes (mixed o,m,p)
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
iso
butyl benzyl carbinol
FL/FR
alpha-
decalactone
FL/FR
(Z)-4-
hepten-1-ol
FL/FR
(Z)-4-
heptenal
FL/FR
(Z)-4-
heptenal diethyl acetal
FL/FR
(E)-2-
hexen-1-yl propionate
FL/FR
syringaldehyde
FL/FR
hay
hay absolute
FR
herbal
immortelle flower oil
FL/FR
mushroom
3-
octen-2-ol
FL/FR
musty
2-
acetyl pyrrole
FL/FR
nutty
2-
acetyl-5-methyl furan
FL/FR
orris
beta-
methyl ionone
FL/FR
powdery
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
soapy
ethyl undecanoate
FL/FR
spicy
methyl heptadienone
FL/FR
myrtenal
FL/FR
sweet
vanilla oleoresin bali
FL/FR
tonka
6-
amyl-alpha-pyrone
FL/FR
coumarin
FR
deertongue absolute
FR
deertongue concrete
FR
deertongue oleoresin
FR
flouve absolute
FR
gamma-
hexalactone
FL/FR
melilot absolute
FR
7-
methyl coumarin
CS
mint lactone
FL/FR
octahydrocoumarin
FL/FR
tonka undecanone
FR
whiskey lactone
FL/FR
tropical
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
vanilla
ortho-
dimethyl hydroquinone
FL/FR
ethyl vanillin
FL/FR
ethyl vanillin isobutyrate
FL/FR
ethyl vanillin propylene glycol acetal
FL/FR
heliotropyl alcohol
FL/FR
propenyl guaethol
FL/FR
vanillin
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
vanillylidene acetone
FL/FR
vegetable
methional
FL/FR
waxy
allyl nonanoate
FL/FR
1-
dodecanol
FL/FR
ethyl palmitate
FL/FR
methyl laurate
FL/FR
myristyl alcohol
FL/FR
2-
nonanol
FL/FR
octyl isobutyrate
FL/FR
delta-
tetradecalactone
FL/FR
2-
tridecanone
FL/FR
undecanoic acid
FL/FR
For Flavor
No flavor group found for these
allyl methyl trisulfide
FL
coconut naphthalenone
FL/FR
coumane
FL/FR
alpha-
decalactone
FL/FR
6-
decenoic acid
FL
(S)-
dihydroactinidiolide
FL
dimethyl benzofuranone
FL
ortho-
dimethyl hydroquinone
FL/FR
delta-2-
dodecenolactone
FL/FR
4-
ethoxy-3-anisaldehyde
FL
farnesyl acetone
FL/FR
fig leaf absolute
FL
heliotropyl alcohol
FL/FR
jasmin lactone (IFF)
FL/FR
lauric acid
FL/FR
massoia bark oil
FL
melilot oleoresin
FL
7-
methoxycoumarin
FL
myristyl alcohol
FL/FR
4-
octen-3-one
FL
pine needle absolute
FL/FR
black
poplar bud oleoresin
FL/FR
propyl octanoate
FL/FR
tonka furanone
FL/FR
(R)-
tonka furanone
FL
wine lactone
FL/FR
acidic
acidic
levulinic acid
FL/FR
aldehydic
acetyl nonyryl
FL/FR
amber
iso
butyl benzyl carbinol
FL/FR
animal
6-
methyl quinoline
FL/FR
anisic
para-
acetanisole
FL/FR
balsamic
vanillylidene acetone
FL/FR
brown
2-oxo
butyric acid
FL/FR
buttery
butter cream frosting flavor
FL
butyl laevo-lactate
FL/FR
diacetyl
FL
cabbage
methyl 2-thiofuroate
FL
caramellic
fenugreek absolute
FL/FR
strawberry furanone acetate
FL/FR
cheesy
2-
heptanone
FL/FR
cherry
heliotropin
FL/FR
chocolate
chocolate vanilla flavor
FL
citrus
lime oil expressed florida
FL/FR
cocoa
syringaldehyde
FL/FR
coconut
delta-
decalactone
FL/FR
(R)-
massoia lactone
FL
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
octahydrocoumarin
FL/FR
delta-
octalactone
FL/FR
coumarinic
phthalide
FL/FR
creamy
acetoin
FL/FR
acetyl butyryl
FL/FR
acetyl isobutyryl
FL/FR
6-
amyl-alpha-pyrone
FL/FR
alpha-
angelica lactone
FL/FR
para-
anisaldehyde
FL/FR
butyl butyryl lactate
FL/FR
creamy lactone
FL/FR
5,5-
dibutyl dihydrofuran-2(3H)-one
FL
dihydrocoumarin
FL
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
gamma-
hexalactone
FL/FR
para-
methyl acetophenone
FL/FR
mint lactone
FL/FR
delta-
nonalactone
FL/FR
octyl isobutyrate
FL/FR
delta-
undecalactone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
para-
vanillic acid
FL/FR
para-
vanillyl alcohol
FL/FR
dairy
butyl lactate
FL/FR
methyl (Z)-5-octenoate
FL/FR
earthy
1-
nonen-3-ol
FL/FR
fatty
(Z)-
dairy lactone
FL/FR
ethyl undecylenate
FL/FR
4-
methyl octanoic acid
FL/FR
2,4-
octadien-1-ol
FL
2-
tridecanone
FL/FR
floral
beta-
methyl ionone
FL/FR
alpha-iso
methyl ionone (50% min.)
FL/FR
orris rhizome resinoid (iris pallida)
FL/FR
rhodinyl acetate
FL/FR
fruity
acetoin acetate
FL/FR
acetyl isovaleryl
FL
bitter
almond oil
FL/FR
amyl heptanoate
FL/FR
iso
amyl octanoate
FL/FR
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
apricot vanilla flavor
FL
cherry propanol
FL/FR
gamma-
decalactone
FL/FR
dimethyl anthranilate
FL/FR
3-
heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR
4-
hydroxybenzyl alcohol
FL/FR
petitgrain mandarin oil terpeneless
FL/FR
iso
propyl octanoate
FL/FR
tolualdehydes (mixed o,m,p)
FL/FR
green
heptanal 2,3-butane diol acetal
FL
(Z)-4-
hepten-1-ol
FL/FR
(Z)-4-
heptenal
FL/FR
(Z)-4-
heptenal diethyl acetal
FL/FR
(E)-2-
hexen-1-yl propionate
FL/FR
immortelle absolute
FL/FR
methyl heptadienone
FL/FR
herbal
immortelle flower oil
FL/FR
lactonic
gamma-
heptalactone
FL/FR
delta-
heptalactone
FL/FR
gamma-
octalactone
FL/FR
meaty
4-
allyl-2,6-dimethoxyphenol
FL
milky
gamma-
butyrolactone
FL/FR
minty
myrtenal
FL/FR
mushroom
3-
octen-2-ol
FL/FR
nutty
2-
acetyl pyrrole
FL/FR
2-
acetyl-5-methyl furan
FL/FR
powdery
powdery ketone
FL
rummy
vanillyl ethyl ether
FL/FR
soapy
1-
dodecanol
FL/FR
sour
butyric acid
FL/FR
spicy
benzyl cinnamate
FL/FR
benzylidene acetone
FL
cinnamon vanilla cream flavor
FL
levisticum officinale oleoresin
FL
root beer float flavor
FL
sweet
ethyl 3-(2-hydroxyphenyl) propionate
FL
orange vanilla cream flavor
FL
vanilla oleoresin bali
FL/FR
toasted
acetyl propionyl
FL/FR
tomato
methional
FL/FR
vanilla
ethyl vanillin
FL/FR
ethyl vanillin isobutyrate
FL/FR
ethyl vanillin propylene glycol acetal
FL/FR
vanilla
ice cream flavor
FL
propenyl guaethol
FL/FR
vanillin
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
waxy
allyl nonanoate
FL/FR
dihydrojasmone lactone
FL/FR
ethyl palmitate
FL/FR
ethyl undecanoate
FL/FR
methyl laurate
FL/FR
2-
nonanol
FL/FR
octyl 2-furoate
FL
octyl butyrate
FL/FR
delta-
tetradecalactone
FL/FR
undecanoic acid
FL/FR
woody
(E)-beta-
ionone
FL/FR
whiskey lactone
FL/FR
 
Potential Uses:
FRamber
FRbalsam
FLcaramel
FLcoconut
FLdate
FRfern
FLfig
FRhay new mown hay
FRincense
FRlabdanum
FRlavender
FLmimosa
FRmoss
FRmyrrh
 oral care agents
FRoriental
FRtonka bean
FLvanilla
FRwoody
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2H-1-benzopyran-2-one, 6-methyl-
 cocodescol
 coumarin, 6-methyl-
6-methyl benzopyrone
6-methyl coumarin synthetic
6-methyl coumarine
6-methyl-1,2-benzopyrone
5-methyl-2-hydroxyphenyl propenoic acid lactone
5-methyl-2-hydroxyphenylpropenoic acid lactone
6-methyl-2H-1-benzopyran-2-one
6-methyl-2H-chromen-2-one
 methyl-6 coumarin
6-methyl-cis-o-coumarinic lactone
6-methyl-cis-ortho-coumarinic lactone
6-methylbenzopyrone
6-methylchromen-2-one
6-methylcoumarin
6-methylcoumarin crystal
6-methylcoumarin powder
 pralina
 toncair
 toncarine
 

Articles:

Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed:Aquatic toxicity assessment of the additive 6-methylcoumarine using four experimental systems.
PubMed:Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat.
PubMed:A predictive mouse ear-swelling model for investigating topical photoallergy.
PubMed:Use of the occlusive patch to evaluate the photosensitive properties of chemicals in guinea-pigs.
PubMed:Regulatory issues concerning AETT and 6-MC.
PubMed:Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition.
PubMed:Supramolecular photocatalysis: insights into cucurbit[8]uril catalyzed photodimerization of 6-methylcoumarin.
PubMed:Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells.
PubMed:Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.
PubMed:Vibrational and ab initio studies of 3-acetyl-6-bromocoumarin and 3-acetyl-6-methylcoumarin.
PubMed:Supramolecular photocatalysis by confinement--photodimerization of coumarins within cucurbit[8]urils.
PubMed:Development of an in vitro photosensitization assay using human monocyte-derived cells.
PubMed:Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici.
PubMed:Simultaneous determination of 6-methylcoumarin and 7-methoxycoumarin in cosmetics using three-dimensional excitation-emission matrix fluorescence coupled with second-order calibration methods.
PubMed:Aquatic toxicity assessment of the additive 6-methylcoumarine using four experimental systems.
PubMed:Infrared study of 6-methylcoumarin in binary solvent mixtures.
PubMed:In vitro phototoxicity test using artificial skin with melanocytes.
PubMed:Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.
PubMed:Causal agents of photoallergic contact dermatitis diagnosed in the national institute of dermatology of Colombia.
PubMed:Fourier transform-infrared and Raman spectra, ab initio calculations and assignments for 6-methyl-4-bromomethylcoumarin.
PubMed:Photoallergic contact sensitization to 6-methylcoumarin in poikiloderma of Civatte.
PubMed:Selectivity in the photodimerization of 6-alkylcoumarins.
PubMed:Use of human reconstituted epidermis Episkin for assessment of weak phototoxic potential of chemical compounds.
PubMed:Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.
PubMed:Photochemical formation of singlet molecular oxygen ((1)O2) in illuminated 6-methylcoumarin solutions.
PubMed:Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat.
PubMed:Photoallergic contact dermatitis. Results of photopatch testing in New York, 1985 to 1990.
PubMed:The phototoxicity of 8-methoxythionepsoralen and 6-methylthionecoumarin.
PubMed:A predictive mouse ear-swelling model for investigating topical photoallergy.
PubMed:Use of UVB and UVA to induce and elicit contact photoallergy in the mouse.
PubMed:Use of the occlusive patch to evaluate the photosensitive properties of chemicals in guinea-pigs.
PubMed:Perfume dermatitis.
PubMed:Mechanisms of contact photosensitivity in mice. III. Predictive testing of chemicals with photoallergenic potential in mice.
PubMed:[New data on photoallergy].
PubMed:Determination of coumarin and 6-methylcoumarin in cosmetics by high-performance liquid chromatography.
PubMed:Experimental photoallergic contact dermatitis: a mouse model.
PubMed:The guinea pig as a model for predicting photoallergic contact dermatitis.
PubMed:Perfume dermatitis. Part II. Photodermatitis to Musk Ambrette and 6-methylcoumarin.
PubMed:Evaluation of the photocontact allergenic potential of 6-methylcoumarin in the guinea pig.
PubMed:Photomaximization test for identifying photoallergic contact sensitizers.
PubMed:Regulatory issues concerning AETT and 6-MC.
PubMed:Contact photoallergy to 6-methylcoumarin in proprietary sunscreens.
PubMed:Photocontact allergy to 6-methylcoumarin.
PubMed:Caffeine, caffeine derivatives and chromosomal aberrations. II. Different responses of Allium root tips and Chinese hamster cells to treatments with caffeine, 8-ethoxycaffeine and 6-methylcoumarin.
 
Notes:
Coumarin replacer. synthetic fragrance causing contact photoallergy. Used as a food additive [EAFUS]
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