EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

omega-pentadecalactone
exaltolide (Firmenich)

Sponsors

Fragrance Demo Formulas
Flavor Demo Formulas
Name:16-oxacyclohexadecan-1-one
CAS Number: 106-02-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:203-354-6
FDA UNII:OK17S3S98K
Nikkaji Web:J4.546B
Beilstein Number:0143710
MDL:MFCD00039667
CoE Number:181
XlogP3-AA:5.80 (est)
Molecular Weight:240.38656000
Formula:C15 H28 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:239 omega-pentadecalactone
FLAVIS Number:10.004 (Old)
DG SANTE Food Flavourings:10.004 pentadecano-1,15-lactone
FEMA Number:2840 omega-pentadecalactone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: OMEGA-PENTADECALACTONE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
 
Physical Properties:
Appearance:colorless solid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 34.00 to 38.00 °C. @ 760.00 mm Hg
Boiling Point: 137.00 °C. @ 2.00 mm Hg
Congealing Point:36.00 °C.
Flash Point:> 220.00 °F. TCC ( > 104.44 °C. )
logP (o/w): 6.100
Shelf Life: 36.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 dipropylene glycol
 water, 0.1484 mg/L @ 25 °C (est)
Stability:
 alcoholic solution: 0.5 - 5%
 antiperspirant
 candle: 0.5 - 5%
 deodorant spray
 detergent: 0.5 - 5%
 hair spray
 lotion
 non-discoloring in most media
 soap: 0.5 - 5%
 shampoo: 0.5 - 5%
 shower gel: 0.5 - 5%
 softener: 0.5 - 5%
 APC: 0.5 - 5%
 
Organoleptic Properties:
Odor Type: musk
Odor Strength:high ,
recommend smelling in a 10.00 % solution or less
Substantivity:400 hour(s) at 10.00 % in dipropylene glycol
musk animal powdery natural fruity
Odor Description:at 10.00 % in dipropylene glycol. musk animal powdery natural fruity
Luebke, William tgsc, (1983)
Odor sample from: Firmenich Inc.
tobacco coumarinic heliotrope powdery licorice brown
Odor Description:Tobacco, coumarin, heliotropine, powdery, licorice and brown
Mosciano, Gerard P&F 22, No. 5, 67, (1997)
Flavor Type: vanilla
vanilla powdery heliotrope creamy licorice
Taste Description: at 75.00 ppm. Vanilla bean, powdery heliotropine, creamy and licorice
Mosciano, Gerard P&F 22, No. 5, 67, (1997)
Odor and/or flavor descriptions from others (if found).
Firmenich
EXALTOLIDE® TOTAL
Odor Description:This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural
EXALTOLIDE® TOTAL adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin.
Taste Description:sweet powdery soapy
Firmenich
EXALTOLIDE®
Odor Description:An extremely fine and elegant musk. EXALTOLIDE® is one of the finest synthetic musk notes that possesses a very natural quality
EXALTOLIDE® adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin.
Taste Description:sweet powdery soapy
Symrise
Macrolide® supra
Odor Description:warm, elegant, cosmetic and caring balsamic musk type with floral elements
Stable in: body lotion (good), shampoo (good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (poor), cleaner apc (very good), bleach (poor).
Taste Description:musk, perfumistic, fruity, berry-like
Useful in: brown nuts, vanilla, fruity red, fruity tropical, fruity others, sweet others, alcoholics.
Symrise
Macrolide®
Odor Description:fine, elegant macrocyclic musk lactone note with a high impact and animalic, balsamic notes
Stable in: body lotion (good), shampoo (very good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (good), cleaner apc (very good), bleach (poor).
Moellhausen
macrolide
Odor Description:powerful musk, herbal note (angelica root- like)
Taste Description:sweet, soap, musk-pear like
Bedoukian Research
PENTALIDE (CYCLOPENTADECANOLIDE) 98.5% (sum of isomers)
Odor Description:An elegant, pleasant sweet animal musky note
Especially useful in alcoholic, cosmetic, and soap fragrances.
Taste Description:musk
Vanilla bean, powdery heliotropine, creamy & licorice.
PerfumersWorld
Exaltolide Pentadecanolide
Odor Description:sweet powdery musk woody powerful musk
Pell Wall Perfumes
Exaltolide
Odor Description:sweet, musky-animal, rich, herbal
Arctander describes it like this: “Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity. Its fixative effect is absolutely unusual in that it is not a physical fixation, but a true fixative and mellowing effect at incredibly low concentrateion of usage. The effect of perfumes containing this Lactone differ from others in the excellent ‘wearability’ introduced by the Lactone. This is particularly conspicuous when the perfume is applied to the skin.” According to Philip Kraft, Exaltolide “is probably the commercial musk with the least side notes.” He therefore recommends using it as a benchmark for grasping the typical odor profile of musk odorants.
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
perfuming agents
 
Suppliers:
Associate Allied Chemicals
Macrolide Supra
About
Augustus Oils
Cyclopentadecanolide
Services
Aurochemicals
omega-PENTADECALACTONE, Natural
Azelis UK
EXALTOLIDE TOTAL
Services
Azelis UK
EXALTOLIDE
Bedoukian Research
PENTALIDE (CYCLOPENTADECANOLIDE)
98.5% (sum of isomers)
Odor: An elegant, pleasant sweet animal musky note
Use: Especially useful in alcoholic, cosmetic, and soap fragrances.
Flavor: musk
Vanilla bean, powdery heliotropine, creamy & licorice.
Berjé
Cyclo Penta Decanolide
Happening at Berje
BOC Sciences
For experimental / research use only.
Oxacyclohexadecan-2-one 95%
CG Herbals
Macrolide Supra
Odor: elegant macrocyclic musk lactone with a high impact and animalic, balsamic notes
Use: Macrolide Supra can be used in a wide range of applications and perfume types. it harmonizes perfectly in all floral and fruity odors and adds musky animalic notes. Synergistic effects are achieved by combining e.g. 66 parts Macrolide with 17 parts esch of the macrocyclic musk (MCM) ketonnes Globanone and Isomuscone.
CG Herbals
Pentalide
CG Herbals
Thibetolide
Creatingperfume.com
EXALTOLIDE® TOTAL
Creatingperfume.com
Macrolide® supra (Symrise)
Odor: Musky, balsamic, red fruit
Ernesto Ventós
CYCLOPENTADECANOLIDE (MACROLIDE)
Ernesto Ventós
EXALTOLIDE FIRMENICH 941962
Ernesto Ventós
EXALTOLIDE TOTAL FIRMENICH 935985
Firmenich
EXALTOLIDE® TOTAL
Odor: This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural
Use: EXALTOLIDE® TOTAL adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin.
Firmenich
EXALTOLIDE®
Odor: An extremely fine and elegant musk. EXALTOLIDE® is one of the finest synthetic musk notes that possesses a very natural quality
Use: EXALTOLIDE® adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin.
Indukern F&F
PENTALIDE
Odor: MUSK, HERBAL
Indukern F&F
THIBETOLIDE
Liaison Carbone
EXALTOLIDE® 941962
Lluch Essence
CYCLO PENTA DECANOLIDE 98,5%
PCW France
Pentadecanolide
Steps to a fragranced product
Pell Wall Perfumes
Exaltolide
Odor: sweet, musky-animal, rich, herbal
Use: Arctander describes it like this: “Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity. Its fixative effect is absolutely unusual in that it is not a physical fixation, but a true fixative and mellowing effect at incredibly low concentrateion of usage. The effect of perfumes containing this Lactone differ from others in the excellent ‘wearability’ introduced by the Lactone. This is particularly conspicuous when the perfume is applied to the skin.” According to Philip Kraft, Exaltolide “is probably the commercial musk with the least side notes.” He therefore recommends using it as a benchmark for grasping the typical odor profile of musk odorants.
Penta International
CYCLOPENTADECANOLIDE FCC, Kosher
Penta International
CYCLOPENTADECANOLIDE, Kosher
Perfumer Supply House
Exaltolide 100%
Odor: A sweet musky animalic note
PerfumersWorld
Exaltolide Pentadecanolide 50% in DPG
PerfumersWorld
Exaltolide Pentadecanolide
Odor: sweet powdery musk woody powerful musk
Perfumery Laboratory
EXALTOLID ™ 100 Firmenich (EXALTOLIDE ™ 100 Firmenich)
Odor: Elegant sweet musk with a delicate animalistic touch
Phoenix Aromas & Essential Oils
Cyclopentadecanolide
Reincke & Fichtner
omega-Pentadecalactone
Sigma-Aldrich
omega-Pentadecalactone, ≥98%, FG
Certified Food Grade Products
Soda Aromatic
Pentalide
Symrise
Macrolide® supra
Odor: warm, elegant, cosmetic and caring balsamic musk type with floral elements
Use: Stable in: body lotion (good), shampoo (good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (poor), cleaner apc (very good), bleach (poor).
Flavor: musk, perfumistic, fruity, berry-like
Useful in: brown nuts, vanilla, fruity red, fruity tropical, fruity others, sweet others, alcoholics.
Symrise
Macrolide®
Odor: fine, elegant macrocyclic musk lactone note with a high impact and animalic, balsamic notes
Use: Stable in: body lotion (good), shampoo (very good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (good), cleaner apc (very good), bleach (poor).
Synerzine
omega-Pentadecalactone
TCI AMERICA
For experimental / research use only.
15-Pentadecanolactone >98.0%(GC)
The John D. Walsh Company
Exaltolide
The Lermond Company
Exaltolide
The Perfumers Apprentice
Exaltolide 100 (50% IPM)
Odor: Fine, elegant, sweet musk note. delicately animal
The Perfumers Apprentice
Exaltolide 100 (Crystalline Solid)
Odor: Fine, elegant, sweet musk note. delicately animal
Treatt
Cyclo Penta Decanolide
Vigon International
Exaltolide Total
Vigon International
Exaltolide
Vigon International
Macrolide Supra (omega Pentadecalactone)
Odor: This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
N - Dangerous for the environment.
R 53 - May cause long-term adverse effects in the aquatic wnvironment.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
GHS Label elements, including precautionary statements
 
Pictogramexclamation-mark.jpg
 
Signal word Warning
Hazard statement(s)
H302 - Harmful if swallowed
Precautionary statement(s)
P264 - Wash skin thouroughly after handling.
P270 - Do not eat, drink or smoke when using this product.
P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 - Rinse mouth.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Human Experience:
10 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg
(Levenstein, 1974c)

oral-rat LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 787, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 787, 1975.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.16 % (1)
Category 2:  0.20 %
Category 3:  0.83 %
Category 4:  2.50 %
Category 5:  1.31 %
Category 6:  3.93 % (1)
Category 7:  0.42 %
Category 8:  2.00 %
Category 9:  5.00 %
Category 10:  2.50 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Maximised Survey-derived Daily Intakes (MSDI-EU): 73.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -1.50000
beverages(nonalcoholic): -0.27000
beverages(alcoholic): -0.50000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.68000
fruit ices: -0.68000
gelatins / puddings: -0.10000
granulated sugar: --
gravies: --
hard candy: -1.40000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
EPA Substance Registry Services (TSCA):106-02-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :235414
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 3077
WGK Germany:1
16-oxacyclohexadecan-1-one
Chemidplus:0000106025
RTECS:RN9775000 for cas# 106-02-5
 
References:
 16-oxacyclohexadecan-1-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:106-02-5
Pubchem (cid):235414
Pubchem (sid):134971488
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):HMDB34455
FooDB:FDB012864
Export Tariff Code:2932.29.6000
Household Products:Search
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
aldehydic
9-
decenal
FL/FR
dodecanal (aldehyde C-12 lauric)
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
amber
ambergris naphthol
FR
ambrinol
FR
alpha-
ambrinol
FL/FR
ambroxan
FL/FR
angelica root oil
FL/FR
cistus ladaniferus resinoid
FR
animal
animal carbolactone
FR
animal specialty
FR
iso
butyl quinoline
FR
costus valerolactone
FR
para-
cresyl caprylate
FL/FR
indole
FL/FR
musk indenofuran
FR
procavia capensis excrete absolute
FR
anisic
para-
acetanisole
FL/FR
ambrette seed oil
FL/FR
para-
anisaldehyde
FL/FR
balsamic
iso
amyl benzoate
FL/FR
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzophenone
FR
benzyl cinnamate
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
cinnamyl alcohol
FL/FR
clover nitrile
FR
ethyl cinnamate
FL/FR
fir balsam absolute
FR
methyl (E)-cinnamate
FL/FR
3-
phenyl propyl alcohol
FL/FR
berry
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
caramellic
ethyl maltol
FL/FR
citrus
bergamot oil bergaptene reduced italy
FL/FR
grapefruit pentanol
FR
blood
orange oil italy
FL/FR
creamy
para-
vanillic acid
FL/FR
earthy
muscogene
FR
fatty
decanol
FL/FR
floral
alpha-
amyl cinnamaldehyde
FL/FR
iso
amyl salicylate
FL/FR
benzyl acetate
FL/FR
bois de rose oil brazil
FL/FR
iso
butyl salicylate
FL/FR
citronellol
FL/FR
coriander seed oil
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
9-
decen-1-ol
FL/FR
dihydrojasmone
FL/FR
dimethyl benzyl carbinol
FL/FR
ethyl phenyl acetate
FL/FR
floral pyranol
FR
gardenia oxide
FR
geraniol
FL/FR
geranyl acetate
FL/FR
heliotropin
FL/FR
heliotropyl acetone
FL/FR
heliotropyl diethyl acetal
FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hyacinth ether
FR
hydroxycitronellal
FL/FR
leerall
FR
lilyall
FR
linalool
FL/FR
laevo-
linalool
FL/FR
linalool oxide
FL/FR
para-
methyl acetophenone
FL/FR
methyl dihydrojasmonate
FL/FR
muguet carboxaldehyde
FR
muguet octadienol
FR
nerol
FL/FR
nerolidol
FL/FR
nonanol
FL/FR
ocean propanal
FL/FR
orris pyridine 25% IPM
FR
peony alcohol
FR
phenethyl alcohol
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl phenyl acetate
FL/FR
phenethyl propionate
FL/FR
phenethyl salicylate
FL/FR
rhodinol
FL/FR
rose butanoate
FL/FR
tetrahydrolinalool
FL/FR
violet methyl carbonate
FR
fresh
10-
undecen-1-yl acetate
FL/FR
fruity
allyl amyl glycolate
FR
artemisia pallens herb oil
FL/FR
benzyl propionate
FL/FR
(E)-alpha-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
gamma-
decalactone
FL/FR
green acetate
FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl benzoate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-
leaf acetal
FL/FR
melon nonenoate
FL/FR
violet leaf absolute
FL/FR
hay
beeswax absolute
FL/FR
hay absolute
FR
herbal
clary sage oil france
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
linalyl acetate
FL/FR
honey
methyl phenyl acetate
FL/FR
melon
watermelon ketone
FR
mossy
oakmoss absolute
FL/FR
veramoss (IFF)
FR
musk
(Z)-
ambrettolide
FL/FR
cyclohexadecanone
FR
exaltone (Firmenich)
FR
juniper muscone
FR
delta-
muscenone
FR
dextro,laevo-
muscone
FL/FR
(R)-
muscone
FR
musk cyclopentenyl propionate
FR
musk dimethyl indane
FL/FR
(Z)-
musk pentane
FR
polvolide (Soda)
FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
powdery
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
spicy
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
iso
eugenyl acetate
FL/FR
methyl isoeugenol
FL/FR
terpenic
frankincense oil
FL/FR
alpha-
terpineol
FL/FR
thujonic
armoise oil
FR
tonka
coumarin
FR
mint lactone
FL/FR
tonka bean absolute
FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decyl acetate
FL/FR
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
1-
undecanol
FL/FR
woody
amber carbinol
FR
cistus twig/leaf oil
FL/FR
guaiacwood oil
FL/FR
gurjun balsam oil
FR
longifolene
FL/FR
methyl cedryl ketone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
santall
FR
tobacarol (IFF)
FR
vetiver oil haiti
FL/FR
woody acetate
FR
(Z)-
woody amylene
FR
woody propanol
FR
For Flavor
No flavor group found for these
ambrette seed oil
FL/FR
(Z)-
ambrettolide
FL/FR
cistus twig/leaf oil
FL/FR
9-
decenal
FL/FR
methyl (E)-cinnamate
FL/FR
aldehydic
aldehydic
1-
undecanol
FL/FR
amber
alpha-
ambrinol
FL/FR
animal
para-
cresyl caprylate
FL/FR
indole
FL/FR
anisic
para-
acetanisole
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
ethyl cinnamate
FL/FR
berry
heliotropyl acetone
FL/FR
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
brown
beeswax absolute
FL/FR
caramellic
ethyl maltol
FL/FR
cherry
heliotropin
FL/FR
citrus
bergamot oil bergaptene reduced italy
FL/FR
laevo-
linalool
FL/FR
linalool
FL/FR
nerol
FL/FR
blood
orange oil italy
FL/FR
alpha-
terpineol
FL/FR
cooling
iso
butyl salicylate
FL/FR
creamy
para-
anisaldehyde
FL/FR
para-
methyl acetophenone
FL/FR
mint lactone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
para-
vanillic acid
FL/FR
fatty
(Z)-3-
hexen-1-yl benzoate
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
bois de rose oil brazil
FL/FR
citronellol
FL/FR
dihydrojasmone
FL/FR
geraniol
FL/FR
linalyl acetate
FL/FR
methyl dihydrojasmonate
FL/FR
methyl phenyl acetate
FL/FR
ocean propanal
FL/FR
phenethyl alcohol
FL/FR
phenethyl propionate
FL/FR
rhodinol
FL/FR
tetrahydrolinalool
FL/FR
fruity
iso
amyl benzoate
FL/FR
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
artemisia pallens herb oil
FL/FR
benzyl acetate
FL/FR
benzyl propionate
FL/FR
(E)-beta-
damascone
FL/FR
(E)-alpha-
damascone
FL/FR
gamma-
decalactone
FL/FR
rose butanoate
FL/FR
greasy
10-
undecen-1-yl acetate
FL/FR
green
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
cinnamyl alcohol
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
geranyl acetate
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
(Z)-
leaf acetal
FL/FR
linalool oxide
FL/FR
melon nonenoate
FL/FR
nerolidol
FL/FR
oakmoss absolute
FL/FR
violet leaf absolute
FL/FR
herbal
clary sage oil france
FL/FR
coriander seed oil
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
honey
ethyl phenyl acetate
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl phenyl acetate
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
phenethyl salicylate
FL/FR
musk
dextro,laevo-
muscone
FL/FR
musk dimethyl indane
FL/FR
nutty
furfural acetone
FL
powdery
beta-
naphthyl ethyl ether
FL/FR
powdery ketone
FL
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
1-
dodecanol
FL/FR
spicy
benzyl cinnamate
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
iso
eugenyl acetate
FL/FR
methyl isoeugenol
FL/FR
3-
phenyl propyl alcohol
FL/FR
tropical
alpha-
amyl cinnamaldehyde
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decanol
FL/FR
9-
decen-1-ol
FL/FR
decyl acetate
FL/FR
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
nonanol
FL/FR
woody
ambroxan
FL/FR
amyris wood oil
FL/FR
frankincense oil
FL/FR
guaiacwood oil
FL/FR
longifolene
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
vetiver oil haiti
FL/FR
 
Potential Uses:
FRabronia
FRacacia
FRamber
FRambergris
FRambrette oil replacer
FL/FRangelica
FRanimal
 apple crabapple
FRautumn
FRazalea
FRbalsam
 bark
FRbayberry
FRbeeswax absolute replacer
FRblackberry
FRblueberry
FRboronia
FRbouquet
FRboysenberry
 burberry
 cabochard
FRcabreuva wood
 cassia blossom
FRcedar
FRcedar forest
FRchampaca
 chanel #5
FRcherry blossom
 chocolate cacao
FRchypre
FL/FRcistus
FRcitrus
FRcivet
 clean
FRclover
FRcolonia
FRcountry meadow
FRcyclamen
FRdaffodil
FRdaphne
FRdogwood
 dusty
 fantasy blends
FRfern
FRfig
FRfir balsam
FRfir needle oil replacer
 fixer
FRfloral
FRflouve
 flouve blossom
 foliage
FRfrangipani plumeria
FRfreesia
FRgenet
FRginger white ginger
FRgooseberry
FL/FRguaiacwood
FRguava
FRgurjun balsam
FRhawthorn
FRhay new mown hay
FRheather
FRherbal
FRhibiscus
FRhinoki oil replacer
FRhollyberry
FRhuckleberry
 hugonia
FL/FRimmortelle
FRincense
 joy
FRkewda
FRkiwi
 kiwi blossom
FRkumquat
FRlabdanum
FRlavender
FRleather
FRlemon
FLlicorice red licorice
FRlily
FRlily of the valley
FRlime
FRloganberry
FRlotus
FRlychee
FRmango
 millefleurs
FRmimosa
FRmoss
FRmulberry
FRmusk
 oakwood
 ocean sea
FRorange
FRorange blossom
FRorchid
FRoriental
FRpansy
FRpapaya
FRpassion blossom
FRpassion fruit
FRpatchouli
FRpetunia
FRphlox
FRpine
FRpine forest
FRplum
FRpomegranate
 poppy
FRpowder
 privet blossom
FRrain
FRraspberry
FRreseda
FRrhubarb
FRrose
FRrose d'orient
FRrose red rose
FRrose tea rose
FRrose white rose
 rose wild rose
FRsandalwood
FRsoapy sandalwood moss
FRspearmint
FRspice
FRspring rain
FRstephanotis
FRsweet grass
 tabu
FLtea
 timber
FRtobacco
FRtoffee
FRtonka bean
FRtulip
FRvanilla
FRverbena
FRwintergreen
FRwisteria
FRwoodruff
FRwoody
 wool
 
Occurrence (nature, food, other):note
 angelica root oil
Search Trop Picture
 angelica root oil @ 0.85%
Data GC Search Trop Picture
 angelica seed oil CO2 extract @ 7.70%
Data GC Search Trop Picture
 
Synonyms:
15-angelica lactone
 cyclo penta decanolide
16-oxacyclohexadecan-1-one
oxacyclohexadecan-2-one
1-oxa-2-cyclohexadecanone
 exaltex
 exaltolide (Firmenich)
 hexaltolide
15-hydroxypentadecanoic acid e-lactone
15-hydroxypentadecanoic acid lactone
15-hydroxypentadecanoic acid omega-lactone
15-hydroxypentadecanoic acid, lactone
 macrolide (Symrise)
 macrolide non-FEMA
 macrolide supra (Symrise)
 muscolactone
 muskalactone
 muskolactone
2-pentadecalone
 pentadecan-15-olide
 pentadecane-15-olide
 pentadecano-1,15-lactone
15-pentadecanolactone
 pentadecanolid
1,15-pentadecanolide
15-pentadecanolide
 pentalide (Bedoukian)
 pentalide (cyclopentadecanolide)
14-oxytetradecane carbonic acid lactone
 thibetolide
 

Articles:

Google Patents:Preparation of cyclopentadecanolide
PubMed:Exploring the Solid State Properties of Enzymatic Poly(amine-co-ester) Terpolymers to Expand their Applications in Gene Transfection.
Google Patents:Process for the preparation of cyclopentadecanolide
PubMed:Method for preparation, programming, and characterization of miniaturized particulate shape-memory polymer matrices.
PubMed:Micelles of enzymatically synthesized PEG-poly(amine-co-ester) block copolymers as pH-responsive nanocarriers for docetaxel delivery.
PubMed:Evaluation of PEG and mPEG-co-(PGA-co-PDL) microparticles loaded with sodium diclofenac.
PubMed:Characterization of CpdC, a large-ring lactone-hydrolyzing enzyme from Pseudomonas sp. strain HI-70, and its use as a fusion tag facilitating overproduction of proteins in Escherichia coli.
PubMed:Multifunctional hybrid nanocomposites with magnetically controlled reversible shape-memory effect.
PubMed:Evaluation of biodegradable polyester-co-lactone microparticles for protein delivery.
PubMed:Treatment of lung cancer using nanoparticle drug delivery systems.
PubMed:Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers.
PubMed:Upscaling the synthesis of biodegradable multiblock copolymers capable of a shape-memory effect.
PubMed:Fragrance material review on ω-pentadecalactone.
PubMed:Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters.
PubMed:Poly(glycerol adipate-co-ω-pentadecalactone) spray-dried microparticles as sustained release carriers for pulmonary delivery.
PubMed:Lipase-catalyzed copolymerization of dialkyl carbonate with 1,4-butanediol and ω-pentadecalactone: synthesis of poly(ω-pentadecalactone-co-butylene-co-carbonate).
PubMed:One-way and reversible dual-shape effect of polymer networks based on polypentadecalactone segments.
PubMed:Electrospun scaffolds of a polyhydroxyalkanoate consisting of omega-hydroxylpentadecanoate repeat units: fabrication and in vitro biocompatibility studies.
PubMed:Synthesis of omega-hydroxy carboxylic acids and alpha,omega-dimethyl ketones using alpha,omega-diols as alkylating agents.
PubMed:Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen.
PubMed:Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery.
PubMed:Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester.
PubMed:Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol.
PubMed:Synthesis and evaluation of novel polyester-ibuprofen conjugates for modified drug release.
PubMed:New oxa-bridged macrocycles.
PubMed:Encapsulation and release of alpha-chymotrypsin from poly(glycerol adipate-co-omega-pentadecalactone) microparticles.
PubMed:Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification.
PubMed:Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies.
PubMed:Lipase-catalyzed copolymerization of omega-pentadecalactone with p-dioxanone and characterization of copolymer thermal and crystalline properties.
PubMed:Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres.
PubMed:[Analysis of omega-pentadecalactone by thin-layer chromatography].
PubMed:Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis.
PubMed:Human olfactory contrast changes during the menstrual cycle.
PubMed:Macrocyclic musk compounds--an absence of genotoxicity in the Ames test and the in vivo Micronucleus assay.
PubMed:Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.
 
Notes:
A true macrocylcic musk, biodegradeable. synthetic musk odor. Constit. of angelica root oil (Angelica archangelica). Flavouring agent
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