laevo-glutamine
L-glutamine
 
Notes:
a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. it is synthesized from glutamic acid and ammonia. it is the principal carrier of nitrogen in the body and is an important energy source for many cells. Widely distributed in plants, e.g. beetroot. Flavouring ingredient. Dietary supplement Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code.
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve and our roster of products and services continues to grow with us. Personal care ingredients now include a substantial array of luxury and exotic components. Substantial inroads have been made in the nutraceutical and resins markets, with a growing roster of versatile and unique ingredients. And we continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions.
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      Product(s):
      GLUTAMINE, L-
       
  • CTC Organics
    • CTC Organics
      For More Than 40 Year
      Your source for rare aroma chemicals for the flavor and fragrance industy.
      “The world is run by middle men.” The number of times I have heard Dr. Liu utter those words are innumerable. He loved reciting and recording famous quotes and had many of his own. Among his many talents, Dr. Liu had a unique genius in the area of chemistry. He had an uncanny understanding of the pulse of the chemical industry and was a superb salesman.
      US Email: Customer Service
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      Resources
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      Product(s):
      W028 L-glutamine
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
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      US Fax: (973) 740-1839
      Product(s):
      07-28500 L-GLUTAMINE, Kosher
       
  • Sigma-Aldrich
    • Sigma-Aldrich
      Complete Supply Chain
      The perfect blend of products and services that bring your creativity to life.
      Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
      Email: Information
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      Certified Food Grade Products
      Product(s):
      W368401 L-Glutamine
      SDS
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 60 years of synthesis experience and multi-purpose plants enable TCI to offer more than 27,000 products as well as custom synthesis. TCI established overseas facilities in North America, Europe, China and India to serve customers worldwide.
      Email: Sales
      US Email: Sales
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      Tokyo Fax:03-5640-8865
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      Product(s):
      G0063 L-Glutamine >99.0%(T)
       
Synonyms   Articles   Notes   Search
(2S)-2,5-diamino-5-oxopentanoic acid (Click)
CAS Number: 56-85-9Picture of molecule
ECHA EINECS - REACH Pre-Reg: 200-292-1
FDA UNII: 0RH81L854J
Nikkaji Web: J9.170G
Beilstein Number: 1723797
MDL: MFCD00008044
CoE Number: 17007
XlogP3: -3.10 (est)
Molecular Weight: 130.14710000
Formula: C5 H10 N2 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: special dietary and nutritional additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 1430  L-glutamine
Flavis Number: 17.007 (Old)
DG SANTE Food Flavourings: 17.007  L-glutamine
FEMA Number: 3684  L-glutamine
FDA Mainterm: L-GLUTAMINE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.320 Amino acids.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white crystalline powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Melting Point: 185.00 to  205.00 °C. @ 760.00 mm Hg
Boiling Point: 445.57 °C. @ 760.00 mm Hg (est)
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): -1.576 (est)
Soluble in:
 propylene glycol
 water, 4.221e+004 mg/L @ 25 °C (est)
 water, 4.13E+04 mg/L @ 25 °C (exp)
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Organoleptic Properties:
Odor Type: milky
Odor Strength: none
 milky  custard  cocoa  oily  
Odor Description:
at 100.00 %. 
very mild milky custard cocoa oily
Luebke, William tgsc, (2007)
 sweet  
Taste Description:
slightly sweet
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antistatic agents
hair conditioning
skin conditioning
Synonyms   Articles   Notes   Search   Top
Suppliers:
Aceto
Glutamine
AIDP
L-Glutamine (Fermented) 98.5%-101.5%
Ajinomoto USA
AjiPure™ Glutamine
AjiPure™
Flavor: characteristic
Manufactured under cGMP conditions using no materials of animal origin.
Ajinomoto USA
L-Glutamine
Flavor: characteristic
Glutamine is nutritionally classified as a nonessential amino acid. It is also considered a conditionally essential amino acid, since its requirement increases significantly in conditions of accelerated catabolism—such as metabolic stress—so that its demand cannot be met by in vivo synthesis alone.
Anhui Haibei
L-Glutamine
Atlantic Chemicals
L-Glutamine
AuNutra® Industries
L-Glutamine
Carbosynth
For experimental / research use only.
L-Glutamine 99%
Charkit Chemical
GLUTAMINE, L-
CTC Organics
L-glutamine
Dow Chemical
L-Glutamine
Foodchem International
L-Glutamine
Glentham Life Sciences
L-Glutamine
Kerry
Hyprol™ Wheat Protein
Penta International
L-GLUTAMINE, Kosher
Prinova
L-Glutamine FCC
Risun Ingredients
L-Glutamine USP,AJI,FCC
Santa Cruz Biotechnology
For experimental / research use only.
L-Glutamine
Sigma-Aldrich
L-Glutamine
Certified Food Grade Products
TCI AMERICA
For experimental / research use only.
L-Glutamine >99.0%(T)
Zhong Ya Chemical
L-Glutamine
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-man TDLo  27 mg/kg/1W-I
BEHAVIORAL: EUPHORIA
American Journal of Psychiatry. Vol. 141, Pg. 1302, 1984.

oral-mouse LD50  21700 mg/kg
Drugs in Japan Vol. 6, Pg. 228, 1982.

oral-rat LD50  7500 mg/kg
Drugs in Japan Vol. 6, Pg. 228, 1982.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: special dietary and nutritional additives
Recommendation for laevo-glutamine usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 13.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 13
Click here to view publication 13
 average usual ppmaverage maximum ppm
baked goods: -350.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -350.00000
milk products: --
nut products: -350.00000
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: -350.00000
snack foods: --
soft candy: -350.00000
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 56-85-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5961
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 (2S)-2,5-diamino-5-oxopentanoic acid
Chemidplus: 0000056859
RTECS: MA2275100 for cas# 56-85-9
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References:
 (2S)-2,5-diamino-5-oxopentanoic acid
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 56-85-9
Pubchem (cid): 5961
Pubchem (sid): 134972923
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C00064
HMDB (The Human Metabolome Database): HMDB00641
FooDB: FDB012164
YMDB (Yeast Metabolome Database): YMDB00002
Export Tariff Code: 2924.19.8000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
balsamic
balsamic
2-acetyl furanFL/FR
 amyl cinnamateFL/FR
isoamyl cinnamateFL/FR
 butyl cinnamateFL/FR
buttery
 butyl butyryl lactateFL/FR
caramellic
 fenugreek oleoresinFL/FR
chocolate
isoamyl phenyl acetateFL/FR
 chocolate pyrazine AFL/FR
 cocoa hexenalFL/FR
 cocoa oleoresinFL/FR
 cocoa pentenalFL/FR
2,6-dimethyl pyrazineFL/FR
2,5-dimethyl pyrazineFL/FR
2-methoxypyrazineFL/FR
2-methyl butyraldehydeFL/FR
2,4,5-trimethyl thiazoleFL/FR
cocoa
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
delta-nonalactoneFL/FR
creamy
para-vanillic acidFL/FR
ethereal
isopropyl formateFL/FR
fermented
 butyl laevo-lactateFL/FR
3-methyl-1-pentanolFL/FR
floral
 ethyl phenyl acetateFL/FR
green
 butyl 2-methyl butyrateFL/FR
 phenyl acetaldehydeFL/FR
herbal
gamma-valerolactoneFL/FR
musty
 cocoa butenalFL/FR
3,6-cocoa pyrazineFL/FR
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,3,5-trimethyl pyrazineFL/FR
 vinyl sulfurolFL/FR
roasted
 fenugreek resinoidFL/FR
waxy
 ethyl palmitateFL/FR
 phenethyl octanoateFL/FR
delta-tetradecalactoneFL/FR
2-tridecanoneFL/FR
 
For Flavor
 
No flavor group found for these
 butyl 2-methyl butyrateFL/FR
 butyl cinnamateFL/FR
2-butyl thiopheneFL
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
2(4)-isobutyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazineFL
 chocolate pyrazine AFL/FR
6-decenoic acidFL
4,5-dimethyl-2-ethyl thiazoleFL
2-methoxypyrazineFL/FR
 peanut dithiazineFL
gamma-valerolactoneFL/FR
dextro,laevo-3-(methyl thio) butanoneFL
bitter
 methyl ethoxypyrazineFL
brown
 fenugreek oleoresinFL/FR
buttery
 butyl laevo-lactateFL/FR
delta-tetradecalactoneFL/FR
cabbage
 methyl 2-thiofuroateFL
caramellic
 fenugreek resinoidFL/FR
chocolate
 cocoa oleoresinFL/FR
 cocoa propanalFL
cocoa
 butyraldehydeFL
 cocoa hexenalFL/FR
coconut
(R)-massoia lactoneFL
creamy
 butyl butyryl lactateFL/FR
delta-nonalactoneFL/FR
para-vanillic acidFL/FR
fatty
2-tridecanoneFL/FR
floral
isoamyl cinnamateFL/FR
isoamyl phenyl acetateFL/FR
 cocoa pentenalFL/FR
fruity
 amyl cinnamateFL/FR
 phenethyl octanoateFL/FR
isopropyl formateFL/FR
fusel
2-methyl butyraldehydeFL/FR
green
 cocoa butenalFL/FR
2-ethyl butyraldehydeFL
honey
 ethyl phenyl acetateFL/FR
 phenyl acetaldehydeFL/FR
musty
2,5-dimethyl pyrazineFL/FR
2,3,5-trimethyl pyrazineFL/FR
nutty
2-acetyl furanFL/FR
3,6-cocoa pyrazineFL/FR
2,6-dimethyl pyrazineFL/FR
2,4-dimethyl-5-vinyl thiazoleFL
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
 vinyl sulfurolFL/FR
waxy
 ethyl palmitateFL/FR
whiskey
3-methyl-1-pentanolFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 antistatic agents 
 hair conditioning 
 skin conditioning 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 apple plant
Search Trop  Picture
 carrot root
Search Trop  Picture
 celery root
Search Trop  Picture
 cherry sour cherry fruit
Search Trop  Picture
 currant black currant fruit juice
Search Trop  Picture
 date palm fruit
Search Trop  Picture
 garlic bulb
Search Trop  Picture
 leek wild leek plant
Search Trop  Picture
 onion bulb
Search Trop  Picture
 orange fruit
Search Trop  Picture
 pineapple fruit
Search Trop  Picture
 potato plant
Search Trop  Picture
 sage plant
Search Trop  Picture
 tarragon leaf
Search Trop  Picture
 tarragon root
Search Trop  Picture
 tea leaf
Search Trop  Picture
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Synonyms:
 ajipure glutamine
(2S)-2-amino-4-carbamoyl butanoic acid
(2S)-2-amino-4-carbamoylbutanoic acid
L-aminoglutaramic acid
L-2-aminoglutaramic acid
2-aminoglutaramic acid, L-
L-2-aminoglutaramidic acid
laevo-2-aminoglutaramidic acid
 cebrogen
(S)-2,5-diamino-5-oxo-pentanoic acid
(2S)-2,5-diamino-5-oxopentanoic acid
(S)-2,5-diamino-5-oxopentanoic acid
2,5-diamino-5-oxopentanoic acid, (S)-
 glutamic acid 5-amide
L-glutamic acid 5-amide
 glutamic acid amide
L-glutamic acid g-amide
L-glutamic acid gamma-amide
laevo-glutamic acid gamma-amide
L-glutamic acid-5-amide
laevo-glutamic acid-5-amide
L-glutamid
L-glutamide
laevo-glutamide
L-glutamin
(S)-(+)-glutamine
L-glutamine
L-(+)-glutamine
laevo-(+)-glutamine
L-glutamine (fermented)
L-glutamine FCC
 glutamine-S
 glutamine, L-
 levoglutamid
 levoglutamide
 levoglutamina
 miglu-P
 nutrestore
 pentanoic acid, 2,5-diamino-5-oxo-, (S)-
 stimulina
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Production and optimization of L-glutaminase enzyme from Hypocrea jecorina pure culture.
PubMed: Efficient expression and purification of recombinant glutaminase from Bacillus licheniformis (GlsA) in Escherichia coli.
PubMed: Kokumi-active glutamyl peptides in cheeses and their biogeneration by Penicillium roquefortii.
PubMed: II. Glutamine and glutamate.
PubMed: Continuous production of extracellular L-glutaminase by Ca-alginate-immobilized marine Beauveria bassiana BTMF S-10 in packed-bed reactor.
PubMed: A simultaneous assay method for L-glutamate and L-pyroglutamate contents in soy sauce using a 5-oxoprolinase (without ATP hydrolyzing activity).
PubMed: Portal hyperglutamatemia after dietary supplementation with monosodium glutamate in pigs.
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