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ethyl furaneol
2-ethyl-4-hydroxy-5-methylfuran-3-one

Supplier Sponsors

Fragrance Demo Formulas
Flavor Demo Formulas
Name:2-ethyl-4-hydroxy-5-methylfuran-3-one
CAS Number: 27538-10-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:248-514-6
FDA UNII: VRF4YF0C3X
Nikkaji Web:J75.508G
Beilstein Number:1617449
XlogP3-AA:1.20 (est)
Molecular Weight:142.15430000
Formula:C7 H10 O3
NMR Predictor:Predict (works with chrome, Edge or firefox)
Also(can) Contains:shoyu furanone
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FEMA Number:3623 2-ethyl-4-hydroxy-5-methylfuran-3-one
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):27538-10-9 ; 2-ETHYL-4-HYDROXY-5-METHYL-3(2H)-FURANONE
 
Physical Properties:
Appearance:yellow to brown clear liquid to crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 103.00 °C. @ 15.00 mm Hg
Boiling Point: 230.00 to 232.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.012000 mmHg @ 25.00 °C. (est)
Flash Point: 184.00 °F. TCC ( 84.44 °C. )
logP (o/w): 0.434 (est)
Soluble in:
 alcohol
 water, 6178 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: caramellic
sweet caramellic candy butterscotch
Odor Description:at 1.00 % in dipropylene glycol. sweet caramel candy butterscotch
Flavor Type: caramellic
sweet caramellic sugar burnt sugar fruity
Taste Description: sweet caramellic burnt sugar fruity
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Advanced Biotech
ETHYL FURANONE 10% IN PG NATURAL
Odor: Berry
Advanced Biotech
ETHYL FURANONE 10% IN PG SYNTHETIC
Odor: Berry, Wine
Advanced Biotech
ETHYL FURANONE 10% IN TRIACETIN NATURAL
Advanced Biotech
ETHYL FURANONE 10% IN TRIETHYL CITRATE NATURAL
Advanced Biotech
ETHYL FURANONE SYNTHETIC
97% min.
Odor: Berry, Wine
Artiste
HomoFuronol Natural
Available as solutions (1%, 5%, 15%, etc.) in various solvents.
Augustus Oils
Homofuranol
Services
Berjé
Sugarone
Media
BOC Sciences
For experimental / research use only.
Ethyl Furaneol
De Monchy Aromatics
ethyl furanone 20% in MPG
De Monchy Aromatics
ethyl furanone
Lluch Essence
ETHYL FRAISION NATURAL
R C Treatt & Co Ltd
2-Ethyl-4-hydroxy-5-methyl-3(2H)furanone 20% in PG
Riverside Aromatics
2-ETHYL-5-METHYL-4-HYDROXY-3[2H]-FURANONE NATURAL
Riverside Aromatics
2-ETHYL-5-METHYL-4-HYDROXY-3[2H]-FURANONE, 20% IN PG
Riverside Aromatics
2-ETHYL-5-METHYL-4-HYDROXY-3[2H]-FURANONE
Santa Cruz Biotechnology
For experimental / research use only.
2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone
Sigma-Aldrich
5-Ethyl-4-hydroxy-2-methyl-3(2H)-furanone, mixture of isomers, 96%, FG
Odor: caramel; fruity
Certified Food Grade Products
Synerzine
2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone - 96%
Synerzine
2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone - 98%
Synerzine
2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone
TCI AMERICA
For experimental / research use only.
2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone >97.0%(T)
Vigon International
ETHYL FURANONE NATURAL 10% IN ETHYL ALCOHOL
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 1932 mg/kg
Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for ethyl furaneol usage levels up to:
  1.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 12
Click here to view publication 12
 average usual ppmaverage maximum ppm
baked goods: -2.00000
beverages(nonalcoholic): -2.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -20.00000
condiments / relishes: --
confectionery froastings: -0.50000
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: -3.00000
granulated sugar: --
gravies: -1.00000
hard candy: -2.00000
imitation dairy: -1.00000
instant coffee / tea: --
jams / jellies: --
meat products: -1.00000
milk products: -0.50000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):27538-10-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :33931
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-ethyl-4-hydroxy-5-methylfuran-3-one
Chemidplus:0027538109
RTECS:LU4250000 for cas# 27538-10-9
 
References:
 2-ethyl-4-hydroxy-5-methylfuran-3-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:27538-10-9
Pubchem (cid):33931
Pubchem (sid):134997586
Flavornet:27538-10-9
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB33736
FooDB:FDB011860
Export Tariff Code:2932.19.5100
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
For Odor
acidic
cyclohexyl acetic acid
FL/FR
balsamic
2-
acetyl furan
FL/FR
iso
amyl pyruvate
FL/FR
bready
furfural
FL/FR
burnt
rum ether
FL/FR
buttery
acetoin
FL/FR
acetyl butyryl
FL/FR
acetyl propionyl
FL/FR
3,4-
hexane dione
FL/FR
caramellic
2-iso
butyl-3-methyl pyrazine
FL/FR
2-oxo
butyric acid
FL/FR
caramel furanone solution
FL/FR
caramel pentadione
FL/FR
coffee dione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
diethyl malate
FL/FR
alpha,alpha-
dimethyl anisyl acetone
FL/FR
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
ethyl cyclopentenolone
FL/FR
ethyl maltol
FL/FR
5-
ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR
fenugreek absolute
FL/FR
geranyl crotonate
FR
hydroxydimethyl cyclopentenone
FR
immortelle absolute
FL/FR
levulinic acid
FL/FR
maltol
FL/FR
maltyl isobutyrate
FL/FR
maltyl propionate
FL/FR
maple furanone
FL/FR
menthone lactone
FL/FR
mesitene lactone
FR
5-
methyl furfural
FL/FR
iso
propenyl pyrazine
FL/FR
rosefuran
FL/FR
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
strawberry furanone solution
FL/FR
toffee furanone
FL/FR
cocoa
2-
methyl butyraldehyde
FL/FR
coconut
gamma-
heptalactone
FL/FR
coffee
1-
hydroxy-2-butanone
FL/FR
coumarinic
tonka bean resinoid
FR
creamy
gamma-
butyrolactone
FL/FR
ethereal
ethyl 4-pentenoate
FL/FR
ethyl pyruvate
FL/FR
fermented
butyl laevo-lactate
FL/FR
ethyl (E)-2-crotonate
FL/FR
ethyl crotonate
FL/FR
floral
beta-
damascenone
FL/FR
orris rhizome absolute (iris pallida)
FL/FR
fruity
iso
butyl 2-butenoate
FL/FR
ethyl lactate
FL/FR
ethyl propionate
FL/FR
(E)-
ethyl tiglate
FL/FR
hexyl (E)-tiglate
FL/FR
methyl nonane dione
FL/FR
2-
pentyl furan
FL/FR
tetrahydrofurfuryl acetate
FL/FR
green
iso
amyl 3-(2-furan) propionate
FL/FR
herbal
butyl levulinate
FL/FR
nutty
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
3,5-
cocoa pyrazine
FL/FR
1,2-
cyclohexane dione
FL/FR
2,3-
dimethyl pyrazine
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
phenolic
4-
methyl-2,6-dimethoxyphenol
FL/FR
spicy
(E)-
propyl 2-furan acrylate
FL/FR
spicy acetoacetate
FL/FR
(E)-
tiglic acid
FL/FR
sweet
vanilla oleoresin bali
FL/FR
tonka
tonka bean absolute
FR
vanilla
ethyl vanillin
FL/FR
vanilla oleoresin bourbon
FL/FR
vanillin
FL/FR
vanillyl isobutyrate
FL/FR
vegetable
tetrahydrofurfuryl alcohol
FL/FR
For Flavor
No flavor group found for these
4-
acetyl-2,5-dimethyl-3(2H)-furanone
FL
2-
acetyl-3,4,5,6-tetrahydropyridine
FL
(E)-
aconitic acid
FL
allyl 2-furoate
FL
iso
amyl pyruvate
FL/FR
benzyl disulfide
FL
1,2-
cyclohexane dione
FL/FR
diethyl malate
FL/FR
2,5-
diethyl tetrahydrofuran
FL
alpha,alpha-
dimethyl anisyl acetone
FL/FR
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
ethyl 4-pentenoate
FL/FR
5-
ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR
furfuryl acetone
FL
menthone lactone
FL/FR
methyl nonane dione
FL/FR
rosefuran
FL/FR
strawberry furanone ethyl ether
FL
iso
amyl 3-(2-furan) propionate
FL/FR
acidic
acidic
levulinic acid
FL/FR
dextro,laevo-
tartaric acid
FL
bready
mango furanone
FL
brown
2-oxo
butyric acid
FL/FR
furfural
FL/FR
1-
hydroxy-2-butanone
FL/FR
5-
methyl furfural
FL/FR
tetrahydrofurfuryl acetate
FL/FR
(E)-
tiglic acid
FL/FR
burnt
furfuryl alcohol
FL
iso
propenyl pyrazine
FL/FR
rum ether
FL/FR
buttery
butter brickle flavor
FL
butter maple flavor
FL
butyl laevo-lactate
FL/FR
diacetyl
FL
3,4-
hexane dione
FL/FR
caramellic
butterscotch flavor
FL
caramel dione
FL
caramel furanone
FL
caramel furanone solution
FL/FR
caramel pentadione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
ethyl maltol
FL/FR
5-
ethyl-3,4,5,6-tetramethyl cyclohexen-2-one
FL
fenugreek absolute
FL/FR
lucuma flavor
FL
maltol
FL/FR
maltyl propionate
FL/FR
maple furanone
FL/FR
3-
methyl butyl 2-furyl butyrate
FL
pyruvaldehyde
FL
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
strawberry furanone solution
FL/FR
toffee furanone
FL/FR
coffee
coffee dione
FL/FR
2-
thiophene thiol
FL
creamy
acetoin
FL/FR
acetyl butyryl
FL/FR
2-
propanoyl thiophene
FL
fatty
diacetyl trimer
FL
(E,E)-2,4-
undecadienal
FL
2,4-
undecadienal
FL
floral
rosa canina seed extract
FL
fruity
date flavor
FL
ethyl lactate
FL/FR
ethyl propionate
FL/FR
(E)-
ethyl tiglate
FL/FR
furfuryl valerate
FL
2-
pentanoyl furan
FL
(E)-
propyl 2-furan acrylate
FL/FR
fusel
2-
methyl butyraldehyde
FL/FR
green
iso
butyl 2-butenoate
FL/FR
2-iso
butyl-3-methyl pyrazine
FL/FR
hexyl (E)-tiglate
FL/FR
immortelle absolute
FL/FR
2-
pentyl furan
FL/FR
herbal
butyl levulinate
FL/FR
5-
hydroxymethyl furfural
FL
honey
honey flavor
FL
jammy
ethyl cyclopentenolone
FL/FR
maltyl isobutyrate
FL/FR
lactonic
gamma-
heptalactone
FL/FR
malty
hordeum vulgare extract (cereal grass)
FL
meaty
2-
mercaptomethyl pyrazine
FL
milky
gamma-
butyrolactone
FL/FR
musty
ethyl (E)-2-crotonate
FL/FR
nutty
2-
acetyl furan
FL/FR
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
aconitic acid
FL
3,5-
cocoa pyrazine
FL/FR
2,3-
dimethyl pyrazine
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
peanut oxazole
FL
tetrahydrofurfuryl alcohol
FL/FR
phenolic
4-
methyl-2,6-dimethoxyphenol
FL/FR
praline
praline flavor
FL
roasted
acer spicatum bark extract
FL
rummy
ethyl crotonate
FL/FR
ethyl pyruvate
FL/FR
smoky
dextro-
xylose
FL
spicy
spicy acetoacetate
FL/FR
sugar
cotton candy flavor
FL
sweet
acetone alcohol
FL
caramel color
FL
cyclohexyl acetic acid
FL/FR
dulce de leche flavor
FL
honey distillates
FL
molasses flavor
FL
orris rhizome absolute (iris pallida)
FL/FR
thaumatin
FL
vanilla oleoresin bali
FL/FR
toasted
acetyl propionyl
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla oleoresin bourbon
FL/FR
vanillin
FL/FR
vanillyl isobutyrate
FL/FR
waxy
furfuryl octanoate
FL
octyl 2-furoate
FL
woody
beta-
damascenone
FL/FR
 
Potential Uses:
FLbarley
FRbutterscotch
FLcandy
FLcaramel
FLchicory root
FRcotton candy
FLegg nog
FL/FRfenugreek
FLginger ale
FRgingerbread
FRgraham cracker
FL/FRimmortelle
FRmalt
FRmaple
FLmarshmallow
FLmolasses
FLpraline
FLsoda cream soda
FLsugar
FLsugar brown sugar
FRtangerine
FRtoffee
FRwormwood oil replacer
 
Occurrence (nature, food, other):note
 blackberry fruit
Search PMC Picture
 cheese
Search PMC Picture
 coffee
Search PMC Picture
 cupuassu
Search Trop Picture
 lovage extract
Search Trop Picture
 raspberry red raspberry fruit
Search Trop Picture
 soya bean paste (miso)
 soya sauce (shoyu)
 
Synonyms:
 ethyl furaneol
 ethyl furanone 10% in PG natural
 ethyl furanone 10% in PG synthetic
 ethyl furanone 10% in triacetin natural
 ethyl furanone 10% in triethyl citrate natural
 ethyl furanone synthetic
2-ethyl-4-hydroxy-5-methyl furan-3(2H)-one
2-ethyl-4-hydroxy-5-methyl-2-hydrofuran-3-one
2-ethyl-4-hydroxy-5-methyl-3-furanone
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone
2-ethyl-4-hydroxy-5-methyl-3(2H)furanone 20% in PG
2-ethyl-4-hydroxy-5-methylfuran-3-one
2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one
2-ethyl-5-methyl-4-hydroxy-3(2H)-furanone
 furan-3(2H)-one, 2-ethyl-4-hydroxy-5-methyl-
homofuraneol
3(2H)-furanone, 2-ethyl-4-hydroxy-5-methyl-
homofuronol (Givaudan)
homofuronol 20% in PG (Givaudan)
homofuronol natural
4-hydroxy-2-ethyl-5-methyl-3-furanone
4-hydroxy-2-ethyl-5-methyl-3(2H)-furanone
2-methyl-4-hydroxy-5-ethylfuran-3-one
 sugarone
 

Articles:

PubMed:Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone.
J-Stage:Enzymatic Synthesis of Stable, Odorless, and Powdered Furanone Glucosides by Sucrose Phosphorylase
PubMed:Main odorants in Jura flor-sherry wines. Relative contributions of sotolon, abhexon, and theaspirane-derived compounds.
PubMed:Identification of sulfur volatiles in canned orange juices lacking orange flavor.
PubMed:Aroma extract dilution analysis of Cv. Marion (Rubus spp. hyb) and Cv. Evergreen (R. laciniatus L.) blackberries.
PubMed:Enzymatic synthesis of stable, odorless, and powdered furanone glucosides by sucrose phosphorylase.
 
Notes:
Volatile flavour and aroma component of Japanese style soya sauce (shoyu) and fermented soya bean paste (miso). Antioxidant. Isol. from Theobroma grandiforum (cupuassu)
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