dihydrocoumarin
3,4-dihydrocoumarin
 
Notes:
Isol. from flowers of Melilotus alba (white melilot) Isol. from Melilotus officinalis (sweet clover). Flavouring ingredient
  • Advanced Biotech
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements. Augustus has invested in modern, well equipped laboratories to provide unparalleled control of quality, and a development environment that continues to produce innovative ranges of natural ingredients. The strength of the company is built on both its comprehensive knowledge base, and extensive stocks of raw materials for both fragrance and flavour use. To complement its range of conventional and Organic Essential Oils and Aroma Chemicals, Augustus also offers a steadily increasing range of its own, UK manufactured Natural Extracts, Absolutes, Resinoids and Natural Chemicals. These again are fully tested and certificated, and very tightly quality controlled. Augustus is committed to promoting the use of natural ingredients, wherever the potential lies and to provide an environment of support and trust to both our customers and suppliers.
      Email: Enquiries
      Email: Sales
      Email: web site enquiries
      Voice: +44 (0)1420 590555
      Fax: +44 (0)1420 592420
      Services
      Product(s):
      Dihydro Coumarin
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
      Mr. Guo86-10-68418739
      News
      Product(s):
      20047 Dihydrocoumarin (natural)
      10749 Dihydrocoumarin
       
  • Berjé
    • Berje Inc.
      The solution is clear
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
      Email: For Information
      Email: For Sales
      Voice: 973-748-8980
      Fax: 973-680-9618
      Flavor Ingredients
      Fragrance Ingredients
      Functional Ingredients
      Happening at Berje
      Product(s):
      Benzo Dihydropyrone
       
  • Elan Inc.
    • Elan Inc.
      Legacy of Innovation
      Highest quality natural and synthetic products.
      Elan Inc. is a privately held business that has been in operation for over 30 years. Our offices and production facility are located in Newark, NJ. We are dedicated to producing the highest quality natural and synthetic products available in the flavor and fragrance industry.
      US Email: Mr. David Pimentel
      US Email: Ms. Isabel Couto
      Email: Elan (Shanghai) Fine Chemical
      Email: Elan do Brazil
      US Voice: (973) 344-8014
      US Fax: (973) 344 -5880
      Voice: +86 021 57448053 (Elan Shanghai)
      Fax: +86 021 57448054 (Elan Shanghai)
      Elan do Brazil:55 13 3261 6084
      Elan do Brazil Fax:55 13 3261 3726
      Custom Solutions
      Product(s):
      BENZO DIHYDRO PYRONE FCC, Kosher
      SDS
       
  • Excellentia International
    • Excellentia International
      Ingredients by Nature
      Exceptional quality and excellence in meeting our customers requirements.
      Excellentia International was founded in 2010 through the merger of Excellentia Flavors LLC and Polarome International. Collectively, these companies account for more than one hundred years of industry experience, and are recognized for exceptional quality and excellence in meeting our customers’ requirements.
      Email: Info
      Email: Sales
      Email: Regulatory
      Voice: 732.749.9840
      Our Services
      Product(s):
      Benzodihydropyrone FCC (Dihydrocoumarin)
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      Email: Information
      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      benzodihydropyrone
       
  • Indukern F&F
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co.
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
      Email: Info
      Email: Sales
      Voice: 86-510-86023169
      Fax: 86-510-86023170
      Mobile0086-13093133011
      Services
      Biochemical
      Natural Food Colour
      New functional food ingredients
      Product(s):
      HLK091 Dihydrocoumarin Natural99%
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
      Linkedin
      Product(s):
      DIHYDROCOUMARIN
      DIHYDROCOUMARIN NATURAL 99%
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. We warmly welcome your inquiries, come witness our solemn commitment for yourself.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      News
      Product(s):
      A0037 DIHYDROCOUMARIN, Kosher
      N0170 NAT.DIHYDROCOUMARIN
       
  • Moellhausen
    • Moellhausen S.P.A.
      THE CHEMISTRY OF EMOTIONS
      Innovation and commitment in the name of excellence.
      After 50 years in business, Moellhausen stands out as one of the world’s leading family-run companies in the industry of flavors and fragrances, raw materials, and specialties. My personal history is inextricably bound to that of the company, and I continue to dedicate all my energy to it along with our partners and collaborators who have supported us thus far with dedication, passion, love, and experience. Continuous investments and a professionalism aimed at achieving the highest levels of performance in service and quality, along with that same dedication, passion, love, and experience, have together enabled us to reach the absolute avant-garde level that characterizes Moellhausen today, recognized worldwide for its modernity, innovation, creativity, and respect for the environment and the safety and rights of those who work with us. As President and CEO of the company for 32 years, I offer a well-deserved thank you to all of our numerous customers, suppliers, employees, and company friends for helping to sustain our unstoppable and honorable growth. And it is with the support of all of our stakeholders that we will confidently continue to pursue our commitment to further advancing the excellence that our industry demands.
      Voice: +39 039.685.6262
      Fax: +39 039.685.6263
      Linkedin
      A network of knowledge to grow together
      Sustainability is at the foundation of a
      Pervasive technology and total control
      Product(s):
      108150 DIHYDROCOUMARIN
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      02-11200 BENZODIHYDROPYRONE, Kosher
      02-11220 BENZODIHYDROPYRONE NATURAL, Kosher
       
  • PerfumersWorld
    • PerfumersWorld Ltd.
      feeeel... the smell!
      The one-stop resource for the creative perfumer.
      No minimum orders. Aroma chemicals, essential oils, isolates, pheremones, absolutes, resinoids, FleuressenceTM key bases, PWx FactorTM, solubilizers, kits, creation systems, workshops, training, distance learning, The PerfumersWorld Perfumer's Studio, The Perfumer’s Formulation Bulletin, perfumery software, bespoke creation, analysis, consultancy, project counselling, trouble-shooting, unperfumed product bases, bottles, smelling strips, scales, distillation, equipment and inspiration!
      Email: Enquiries
      Email: Sales
      Voice: +66(0)2-99-800-80
      Fax: +66(0)2-99-800-80
      PerfumersWorld Skype Skype
      Facebook
      Twitter
      Google+
      Youtube
      Resources
      Software: Perfumer's Workbook
      Product(s):
      1VD00148 Dihydro coumarin
       
  • Phoenix Aromas & Essential Oils
    • Phoenix Aromas & Essential Oils, Inc.
      EXCEPTIONAL Flavor and Fragrance Ingredients.
      Phoenix sources the finest flavor and fragrance ingredients for its customers.
      Phoenix Aromas & Essential Oils LLC was founded in 1994, grounded in a simple set of core values: provide top-quality products, cost-effective pricing and personalized attention to all our customers. After two decades, we remain committed to those values. With extensive market knowledge of our products, we anticipate, as opposed to merely react, to industry challenges. You can rely on us for all your flavor and fragrance ingredient needs. Customers benefit from Phoenix's long-standing relationships with experienced and reputable growers, processors and manufacturers in key global locations, who are committed to sustainability and green programs. With a strategically located 80,000 sq-ft facility, customers can rely on Phoenix to deliver quality products on time, and cost-effectively.
      Email: EU Info
      US Email: Info
      US Email: Sales
      Voice: +44(0) 208 532 1022
      Fax: +44(0) 208 532 1023
      US Voice: 201-784-6100
      US Fax: 201-784-8566
      Global Reach
      Product(s):
      Dihydrocoumarin (Benzodihydropyrone)
       
  • Sigma-Aldrich
    • Sigma-Aldrich
      Complete Supply Chain
      The perfect blend of products and services that bring your creativity to life.
      Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
      Email: Information
      US Email: Sales
      US Voice: 800-244-1173
      US Fax: 800-368-4661
      Facebook
      Twitter
      Instagram
      Linkedin
      Certified Food Grade Products
      Product(s):
      W238104 Dihydrocoumarin, ≥99%, FCC, FG
      SDS
       
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
      Email: Info
      Email: Sales
      Voice: +44 (0) 1284 704076
      Fax: +44 (0) 1284 760819
      Twitter
      Linkedin
      News
      Product(s):
      DIHYDRO COUMARIN
       
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
      Fax: 0512-57570299
      Sales0512-57995626
      Sales0512-57570299
      News
      Product(s):
      A0039 Dihydrocoumarin
       
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
      US Email: Life Essentials
      Email: Aroma Molecules
      Voice: +49 5531 90 0
      Twitter
      Youtube
      Newsroom
      RSS Feed
      Product(s):
      690616 Dihydrocoumarin

      Useful in: brown caramel, brown nuts, brown others, dairy, vanilla, fruity red, fruity tropical, sweet others, alcoholics.
       
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 60 years of synthesis experience and multi-purpose plants enable TCI to offer more than 27,000 products as well as custom synthesis. TCI established overseas facilities in North America, Europe, China and India to serve customers worldwide.
      Email: Sales
      US Email: Sales
      Email: Global Business
      Voice: +81-3-5640-8878
      Fax: +81-3-5640-8902
      US Voice: 800-423-8616
      US Fax: 888-520-1075
      Tokyo Tel:03-5640-8851
      Tokyo Fax:03-5640-8865
      Facebook
      Twitter
      Instagram
      Linkedin
      RSS
      Product(s):
      D1223 3,4-Dihydrocoumarin >98.0%(GC)
       
  • The Lermond Company
    • The Lermond Company
      Your Sourcing Resource
      The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.
      The Lermond Company is a women-owned distributor of raw materials primarily servicing the flavor and fragrance industry. For three generations, members of the Lermond family have been integral sourcing partners for the North American flavor and fragrance industry. We supply high quality essential oils, aroma chemicals, absolutes, concretes, resinoids and floral waters from around the world to the global industry.
      Email: Info
      Email: Tara
      Email: Erica
      Voice: 201-896-3300
      Fax: 201-623-2910
      Facebook
      Linkedin
      Product(s):
      Dihydro Coumarin
       
  • Treatt
    • Treatt PLC
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
      News
      Product(s):
      Dihydrocoumarin
       
  • Ernesto Ventós
  • Vigon International
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas    Flavor Demo Formulas
chroman-2-one (Click)
CAS Number: 119-84-6Picture of molecule
ECHA EINECS - REACH Pre-Reg: 204-354-9
FDA UNII: NM5K1Y1BT2
Nikkaji Web: J36.832F
Beilstein Number: 0004584
MDL: MFCD00006881
CoE Number: 535
XlogP3-AA: 1.60 (est)
Molecular Weight: 148.16116000
Formula: C9 H8 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 1171  dihydrocoumarin
Flavis Number: 13.009 (Old)
DG SANTE Food Flavourings: 13.009  3,4-dihydrocoumarin
FEMA Number: 2381  dihydrocoumarin
FDA Mainterm: DIHYDROCOUMARIN
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to pale yellow clear liquid to solid (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.18600 to 1.19200 @  25.00 °C.
Pounds per Gallon - (est).: 9.869 to  9.919
Refractive Index: 1.54000 to 1.58000 @  20.00 °C.
Melting Point: 24.00 to  25.00 °C. @ 760.00 mm Hg
Boiling Point: 271.00 to  272.00 °C. @ 760.00 mm Hg
Congealing Point: 23.00 °C.
Acid Value: 5.00 max. KOH/g
Vapor Pressure: 4.000000 mm/Hg @ 25.00 °C.
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 2.428 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 water, 3000 mg/L @ 37 °C (exp)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: tonka
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 sweet  tonka  coumarinic  coconut  herbal  cinnamon  
Odor Description:
at 10.00 % in dipropylene glycol. 
sweet tonka coumarin coconut herbal cinnamon
Luebke, William tgsc, (1987)
 sweet  creamy  coconut  coumarinic  vanilla  spicy  
Odor Description:
Sweet, creamy, coconut, coumarin, vanilla with a slight spice nuance
Mosciano, Gerard P&F 17, No. 3, 57, (1992)
 sweet  creamy  vanilla  coconut  milky  
Taste Description:
at 10.00 ppm.  
Sweet, creamy, vanilla, coconut and milky
Mosciano, Gerard P&F 17, No. 3, 57, (1992)
Substantivity: 228 Hour(s)
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: not used anymore
Synonyms   Articles   Notes   Search   Top
Suppliers:
A.C.S. International
Dihydrocumarine
Odor: sweet tonka coumarin coconut herbal cinnamon
Operational Capabilities
Advanced Biotech
BENZO DIHYDROPYRONE NATURAL
98% min.
Odor: Herbaceous, Woody
Advanced Biotech
BENZO DIHYDROPYRONE SYNTHETIC
98% min.
Odor: Herbaceous, Woody
Anhui Haibei
Dihydro coumarin
Odor: Sweetish, fruity or herbal
Aromiens International
Dihydrocoumarin, Natural
Augustus Oils
Dihydro Coumarin
Services
Aurochemicals
BENZODIHYDROPYRONE, Natural
Beijing Lys Chemicals
Dihydrocoumarin (natural)
Beijing Lys Chemicals
Dihydrocoumarin
Bell Flavors & Fragrances
Natural Benzodihydropyrone (BDHP)
Berjé
Benzo Dihydropyrone
Happening at Berje
CG Herbals
DiHydro Coumarin
Citrus and Allied Essences
Benzo Dihydropyrone
Market Report
Diffusions Aromatiques
DIHYDROCOUMARINE
Elan Inc.
BENZO DIHYDRO PYRONE
FCC, Kosher
EMD Millipore
For experimental / research use only.
Dihydrocoumarin
Ernesto Ventós
DIHYDROCOUMARIN
Odor: SWEET,COUMARIN BUT SLIGHTLY BITTER
Excellentia International
Benzodihydropyrone FCC (Dihydrocoumarin)
ExtraSynthese
For experimental / research use only.
3,4-Dihydrocoumarin (GC) ≥95%
Fleurchem
benzodihydropyrone
Indukern F&F
DIHYDROCOUMARIN NATURAL
Odor: SWEET, AROMATIC, COUMARIN, CINNAMON
CROP CALENDAR
Indukern F&F
DIHYDROCOUMARIN
Jiangyin Healthway
Dihydrocoumarin Natural99%
New functional food ingredients
Kunshan Sainty
Dihydrocoumarin, Kosher
Lluch Essence
DIHYDROCOUMARIN NATURAL 99%
Lluch Essence
DIHYDROCOUMARIN
M&U International
DIHYDROCOUMARIN, Kosher
M&U International
NAT.DIHYDROCOUMARIN
Moellhausen
DIHYDROCOUMARIN
Odor: sweet, cocoa
Flavor: sweet, vanilla, milk
Pearlchem Corporation
Dihydro Coumarin
Penta International
BENZODIHYDROPYRONE NATURAL, Kosher
Penta International
BENZODIHYDROPYRONE, Kosher
PerfumersWorld
Dihydro coumarin
Odor: sweet rose coumarin tonka herbal sweet aromatic coumarin coconut
Perfumery Laboratory
TONCAINOL
Odor: Sweet, vanilla with bright notes of beans
Phoenix Aromas & Essential Oils
Dihydrocoumarin (Benzodihydropyrone)
Prinova
Di Hydro Coumarin
Reincke & Fichtner
Dihydrocoumarin
Santa Cruz Biotechnology
For experimental / research use only.
Dihydrocoumarin ≥98%
Sigma-Aldrich
Dihydrocoumarin, ≥99%, FCC, FG
Odor: almond; coconut; creamy; herbaceous; sweet; vanilla; nutty; tobacco.
Certified Food Grade Products
SRS Aromatics
DIHYDRO COUMARIN
Sunaux International
Dihydrocoumarin
Symrise
Dihydrocoumarin
Flavor: coumarin, sweet, caramel, cream, vanilla, woodruff
Useful in: brown caramel, brown nuts, brown others, dairy, vanilla, fruity red, fruity tropical, sweet others, alcoholics.
TCI AMERICA
For experimental / research use only.
3,4-Dihydrocoumarin >98.0%(GC)
Tengzhou Xiang Yuan Aroma Chemicals
Dihydrocoumarin
The Lermond Company
Dihydro Coumarin
The Perfumers Apprentice
Dihydrocoumarin 10% (PG)
Odor: Sweet, creamy, vanilla, coconut and milky
Treatt
Dihydrocoumarin
Universal Preserv-A-Chem Inc.
BENZODIHYDROPYRONE
Vigon International
Dihydrocoumarin FCC
Odor: Sweet-aromatic like coumarin, with pronounced cinnamon and caramel note
Vigon International
Dihydrocoumarin Natural
WEN International
BENZODIHYDROPYRONE, natural
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
20 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50  1460 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

intraperitoneal-mouse LD50  200 mg/kg
National Technical Information Service. Vol. AD277-689

oral-guinea pig LD50  1760 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 521, 1974.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavoring agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.029 % (1)
Category 2:  0.037 %
Category 3:  0.15 %
Category 4:  0.45 %
Category 5:  0.24 %
Category 6:  0.72 % (1)
Category 7:  0.08 %
Category 8:  1.01 %
Category 9:  5.00 %
Category 10:  2.05 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Maximised Survey-derived Daily Intakes (MSDI-EU): 1200.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 1111.00 (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -28.00000
beverages(nonalcoholic): -7.80000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -78.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -21.00000
fruit ices: -21.00000
gelatins / puddings: -10.00000
granulated sugar: --
gravies: --
hard candy: -44.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of lactones used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 80 (FGE.80) - Consideration of alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by JECFA (61st meeting) structurally related to a aromatic lactone evaluated by EFSA in FGE.27 (2008)
View page or View pdf
Flavouring Group Evaluation 80, Revision 1 (FGE.80Rev1): Consideration of alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by JECFA (61st meeting) structurally related to a aromatic lactone evaluated by EFSA in FGE.27 (2008)
View page or View pdf
Scientific Opinion on the safety and efficacy of alicyclic and aromatic lactones (chemical group 11) when used as flavourings for all animal species
View page or View pdf
EPI System: View
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 119-84-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 660
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 3
 chroman-2-one
Chemidplus: 0000119846
EPA/NOAA CAMEO: hazardous materials
RTECS: MW5775000 for cas# 119-84-6
Synonyms   Articles   Notes   Search   Top
References:
 chroman-2-one
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 119-84-6
Pubchem (cid): 660
Pubchem (sid): 134974732
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
Metabolomics Database: Search
UM BBD: Search
KEGG (GenomeNet): C02274
HMDB (The Human Metabolome Database): HMDB36626
FooDB: FDB015543
Export Tariff Code: 2932.20.4500
Haz-Map: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
aldehydic
aldehydic
 acetyl nonyrylFL/FR
amber
 angelica root oilFL/FR
 cistus ladaniferus resinoidFR
animal
 animal carbolactoneFR
 civet absoluteFL/FR
 costus valerolactoneFR
 indoleFL/FR
6-methyl quinolineFL/FR
anisic
para-anisaldehydeFL/FR
balsamic
 amyris wood oilFL/FR
siam benzoin resinoidFL/FR
sumatra benzoin resinoidFL/FR
 benzyl cinnamateFL/FR
 benzyl salicylateFL/FR
isobutyl cinnamateFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 methyl cinnamateFL/FR
 peru balsam oilFL/FR
 pine needle absoluteFL/FR
buttery
 acetoinFL/FR
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
 acetyl propionylFL/FR
 butyl butyryl lactateFL/FR
caramellic
2-oxobutyric acidFL/FR
 ethyl maltolFL/FR
 fenugreek absoluteFL/FR
 immortelle absoluteFL/FR
 strawberry furanone acetateFL/FR
cheesy
 butyric acidFL/FR
2-heptanoneFL/FR
citrus
 lime oil expressed floridaFL/FR
coconut
alpha-angelica lactoneFL/FR
 coconut decanone methylFR
 coconut naphthalenoneFL/FR
delta-decalactoneFL/FR
delta-2-dodecenolactoneFL/FR
delta-heptalactoneFL/FR
gamma-heptalactoneFL/FR
delta-nonalactoneFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
delta-octalactoneFL/FR
gamma-octalactoneFL/FR
 propyl octanoateFL/FR
 tetrahydrojasmoneFR
delta-undecalactoneFL/FR
 wine lactoneFL/FR
 wine lactoneFL/FR
coumarinic
 coumaneFL/FR
 phthalideFL/FR
 tonka bean oleoresinFR
 tonka bean resinoidFR
 tonka furanoneFL/FR
 tonka ketoneFR
 tonkavertFR
creamy
 butyl lactateFL/FR
gamma-butyrolactoneFL/FR
 creamy lactoneFL/FR
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
para-vanillic acidFL/FR
para-vanillic acidFL/FR
para-vanillyl alcoholFL/FR
para-vanillyl alcoholFL/FR
earthy
1-nonen-3-olFL/FR
fatty
(Z)-dairy lactoneFL/FR
 ethyl undecylenateFL/FR
4-methyl octanoic acidFL/FR
fermented
 butyl laevo-lactateFL/FR
floral
 acetophenoneFL/FR
isoamyl salicylateFL/FR
para-anisyl nitrileFR
isobutyl salicylateFL/FR
 cananga oilFL/FR
 dihydrojasmoneFL/FR
 dihydrojasmone lactoneFL/FR
 floral pyranolFR
 heliotropinFL/FR
 heliotropyl acetoneFL/FR
 heliotropyl diethyl acetalFR
 hexenyl cyclopentanoneFR
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
 jasmin lactone (IFF)FL/FR
abrialis lavandin oilFL/FR
 lavender oilFL/FR
para-methyl acetophenoneFL/FR
 nerolidolFL/FR
 ocean propanalFL/FR
 orris rhizome absolute (iris pallida)FL/FR
 palmarosa oilFL/FR
2-pentyl cyclopentanoneFR
 phenethyl phenyl acetateFL/FR
fruity
 acetoin acetateFL/FR
 amyl heptanoateFL/FR
isoamyl octanoateFL/FR
 benzaldehydeFL/FR
 cherry propanolFL/FR
gamma-decalactoneFL/FR
 farnesyl acetoneFL/FR
4-hydroxybenzyl alcoholFL/FR
 methyl (Z)-5-octenoateFL/FR
 octyl butyrateFL/FR
isopropyl octanoateFL/FR
 raspberry ketoneFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
green
isobutyl benzyl carbinolFL/FR
alpha-decalactoneFL/FR
 diphenyl methaneFL/FR
 galbanum oilFL/FR
(Z)-4-hepten-1-olFL/FR
(Z)-4-heptenalFL/FR
(Z)-4-heptenal diethyl acetalFL/FR
 heptyl heptanoateFL/FR
3-phenyl propionaldehydeFL/FR
 syringaldehydeFL/FR
hay
 hay absoluteFR
herbal
 apium graveolens seed oil indiaFL/FR
 immortelle flower oilFL/FR
 linalyl acetateFL/FR
 origanum oil greeceFL/FR
melon
 watermelon ketoneFR
mossy
 oakmoss absoluteFL/FR
 treemoss absoluteFR
 veramoss (IFF)FR
mushroom
3-octen-2-olFL/FR
musty
2-acetyl pyrroleFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
beta-naphthyl ethyl etherFL/FR
beta-naphthyl methyl etherFL/FR
nutty
2-acetyl-5-methyl furanFL/FR
phenolic
ortho-guaiacolFL/FR
powdery
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
soapy
 ethyl undecanoateFL/FR
spicy
 benzyl isoeugenolFL/FR
 croton eluteria bark oilFL/FR
 cubeb oilFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale root oilFL/FR
para-methoxy-alpha-methyl cinnamaldehydeFL/FR
para-methoxycinnamaldehydeFL/FR
alpha-methyl cinnamaldehydeFL/FR
 methyl heptadienoneFL/FR
alpha-methyl-(E)-cinnamaldehydeFL/FR
 myrtenalFL/FR
 nutmeg oilFL/FR
sweet
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla oleoresin baliFL/FR
 vanilla oleoresin baliFL/FR
thujonic
 armoise oilFR
tonka
6-amyl-alpha-pyroneFL/FR
 coumarinFR
 deertongue absoluteFR
 deertongue oleoresinFR
 flouve absoluteFR
gamma-hexalactoneFL/FR
 melilot absoluteFR
7-methyl coumarinCS
 mint lactoneFL/FR
 octahydrocoumarinFL/FR
 tonka bean absoluteFR
 tonka undecanoneFR
 whiskey lactoneFL/FR
 whiskey lactoneFL/FR
tropical
delta-dodecalactoneFL/FR
 glyceryl 5-hydroxydecanoateFL/FR
 glyceryl 5-hydroxydodecanoateFL/FR
vanilla
ortho-dimethyl hydroquinoneFL/FR
 ethyl vanillinFL/FR
 ethyl vanillin isobutyrateFL/FR
 ethyl vanillin propylene glycol acetalFL/FR
 methyl vanillateFL/FR
 propenyl guaetholFL/FR
 vanillinFL/FR
 vanillinFL/FR
 vanillyl acetateFL/FR
 vanillyl acetateFL/FR
 vanillyl isobutyrateFL/FR
 vanillyl isobutyrateFL/FR
 vanillylidene acetoneFL/FR
 vanillylidene acetoneFL/FR
vegetable
 methionalFL/FR
waxy
 allyl nonanoateFL/FR
1-dodecanolFL/FR
 ethyl palmitateFL/FR
 methyl laurateFL/FR
 myristyl alcoholFL/FR
2-nonanolFL/FR
 octyl isobutyrateFL/FR
delta-tetradecalactoneFL/FR
2-tridecanoneFL/FR
 undecanoic acidFL/FR
 undecanoic acidFL/FR
woody
 guaiacwood oilFL/FR
 methyl cedryl ketoneFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 santallFR
 spruce needle oil canadaFL/FR
 tobacarol (IFF)FR
 vetiver oil haitiFL/FR
 vetiver oil haitiFL/FR
 vetiverolFL/FR
 vetiverolFL/FR
 woody acetateFR
(Z)-woody amyleneFR
 woody propanolFR
 
For Flavor
 
No flavor group found for these
 allyl methyl trisulfideFL
 coconut naphthalenoneFL/FR
 coumaneFL/FR
alpha-decalactoneFL/FR
6-decenoic acidFL
(S)-dihydroactinidiolideFL
 dimethyl benzofuranoneFL
ortho-dimethyl hydroquinoneFL/FR
delta-2-dodecenolactoneFL/FR
 farnesyl acetoneFL/FR
 fig leaf absoluteFL
2-furfurylidene butyraldehydeFL
delta-heptalactoneFL/FR
 heptanal 2,3-butane diol acetalFL
 jasmin lactone (IFF)FL/FR
 massoia bark oilFL
 melilot oleoresinFL
para-methoxy-alpha-methyl cinnamaldehydeFL/FR
7-methoxycoumarinFL
6-methyl quinolineFL/FR
 methyl vanillateFL/FR
 myristyl alcoholFL/FR
beta-naphthyl methyl etherFL/FR
4-octen-3-oneFL
 pine needle absoluteFL/FR
 propyl octanoateFL/FR
 syringaldehydeFL/FR
(R)-tonka furanoneFL
 tonka furanoneFL/FR
 vetiverolFL/FR
 vetiverolFL/FR
 wine lactoneFL/FR
 wine lactoneFL/FR
aldehydic
 acetyl nonyrylFL/FR
amber
isobutyl benzyl carbinolFL/FR
animal
 civet absoluteFL/FR
 indoleFL/FR
aromatic
 benzyl isoeugenolFL/FR
 diphenyl methaneFL/FR
balsamic
siam benzoin resinoidFL/FR
sumatra benzoin resinoidFL/FR
 benzyl salicylateFL/FR
isobutyl cinnamateFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 peru balsam oilFL/FR
 vanillylidene acetoneFL/FR
 vanillylidene acetoneFL/FR
berry
 heliotropyl acetoneFL/FR
bitter
 glyceryl tributyrateFL
brown
2-oxobutyric acidFL/FR
buttery
 butter cream frosting flavorFL
 butyl laevo-lactateFL/FR
 diacetylFL
delta-tetradecalactoneFL/FR
cabbage
 methyl 2-thiofuroateFL
caramellic
 caramel furanoneFL
 ethyl maltolFL/FR
 fenugreek absoluteFL/FR
 strawberry furanone acetateFL/FR
cheesy
2-heptanoneFL/FR
cherry
 heliotropinFL/FR
para-methoxycinnamaldehydeFL/FR
citrus
 lime oil expressed floridaFL/FR
coconut
delta-decalactoneFL/FR
(R)-massoia lactoneFL
6-methyl coumarinFL
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
 octahydrocoumarinFL/FR
delta-octalactoneFL/FR
cooling
isobutyl salicylateFL/FR
coumarinic
 phthalideFL/FR
creamy
 acetoinFL/FR
 acetyl butyrylFL/FR
 acetyl isobutyrylFL/FR
6-amyl-alpha-pyroneFL/FR
alpha-angelica lactoneFL/FR
para-anisaldehydeFL/FR
 butyl butyryl lactateFL/FR
 creamy lactoneFL/FR
5,5-dibutyl dihydrofuran-2(3H)-oneFL
delta-dodecalactoneFL/FR
 glyceryl 5-hydroxydecanoateFL/FR
 glyceryl 5-hydroxydodecanoateFL/FR
gamma-hexalactoneFL/FR
 massoia lactoneFL
para-methyl acetophenoneFL/FR
 mint lactoneFL/FR
delta-nonalactoneFL/FR
 octyl isobutyrateFL/FR
delta-undecalactoneFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
para-vanillic acidFL/FR
para-vanillic acidFL/FR
para-vanillyl alcoholFL/FR
para-vanillyl alcoholFL/FR
dairy
 butyl lactateFL/FR
 methyl (Z)-5-octenoateFL/FR
earthy
1-nonen-3-olFL/FR
fatty
(Z)-dairy lactoneFL/FR
 ethyl undecylenateFL/FR
4-methyl octanoic acidFL/FR
2,4-octadien-1-olFL
2-tridecanoneFL/FR
floral
 cananga oilFL/FR
 dihydrojasmoneFL/FR
 linalyl acetateFL/FR
 ocean propanalFL/FR
 palmarosa oilFL/FR
fruity
 acetoin acetateFL/FR
 acetyl isovalerylFL
 amyl heptanoateFL/FR
isoamyl octanoateFL/FR
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
 benzaldehydeFL/FR
 cherry propanolFL/FR
gamma-decalactoneFL/FR
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
4-hydroxybenzyl alcoholFL/FR
isopropyl octanoateFL/FR
 raspberry ketoneFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
green
isoamyl salicylateFL/FR
 angelica root oilFL/FR
 galbanum oilFL/FR
(Z)-4-hepten-1-olFL/FR
(Z)-4-heptenalFL/FR
(Z)-4-heptenal diethyl acetalFL/FR
 heptyl heptanoateFL/FR
 immortelle absoluteFL/FR
 methyl heptadienoneFL/FR
 nerolidolFL/FR
 oakmoss absoluteFL/FR
3-phenyl propionaldehydeFL/FR
herbal
 apium graveolens seed oil indiaFL/FR
 immortelle flower oilFL/FR
abrialis lavandin oilFL/FR
 lavender oilFL/FR
 origanum oil greeceFL/FR
honey
 phenethyl phenyl acetateFL/FR
lactonic
gamma-heptalactoneFL/FR
gamma-octalactoneFL/FR
meaty
4-allyl-2,6-dimethoxyphenolFL
milky
gamma-butyrolactoneFL/FR
minty
 myrtenalFL/FR
(1R)-(-)-myrtenalFL
mushroom
3-octen-2-olFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
nutty
2-acetyl pyrroleFL/FR
2-acetyl-5-methyl furanFL/FR
powdery
 acetophenoneFL/FR
beta-naphthyl ethyl etherFL/FR
 powdery ketoneFL
soapy
1-dodecanolFL/FR
sour
 butyric acidFL/FR
spicy
 benzyl cinnamateFL/FR
 benzylidene acetoneFL
 croton eluteria bark oilFL/FR
 cubeb oilFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale oleoresinFL
 levisticum officinale root oilFL/FR
alpha-methyl cinnamaldehydeFL/FR
 methyl cinnamateFL/FR
alpha-methyl-(E)-cinnamaldehydeFL/FR
 nutmeg oilFL/FR
 root beer float flavorFL
sweet
 ethyl 3-(2-hydroxyphenyl) propionateFL
 orange vanilla cream flavorFL
 orris rhizome absolute (iris pallida)FL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanilla oleoresin baliFL/FR
 vanilla oleoresin baliFL/FR
toasted
 acetyl propionylFL/FR
tomato
 methionalFL/FR
vanilla
 ethyl vanillinFL/FR
 ethyl vanillin isobutyrateFL/FR
 ethyl vanillin propylene glycol acetalFL/FR
vanilla ice cream flavorFL
 propenyl guaetholFL/FR
 vanillinFL/FR
 vanillinFL/FR
 vanillyl acetateFL/FR
 vanillyl acetateFL/FR
 vanillyl isobutyrateFL/FR
 vanillyl isobutyrateFL/FR
waxy
 allyl nonanoateFL/FR
 dihydrojasmone lactoneFL/FR
 ethyl palmitateFL/FR
 ethyl undecanoateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
 methyl laurateFL/FR
2-nonanolFL/FR
 octyl 2-furoateFL
 octyl butyrateFL/FR
 undecanoic acidFL/FR
 undecanoic acidFL/FR
woody
 amyris wood oilFL/FR
ortho-guaiacolFL/FR
 guaiacwood oilFL/FR
 methyl cedryl ketoneFL/FR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 spruce needle oil canadaFL/FR
 vetiver oil haitiFL/FR
 vetiver oil haitiFL/FR
 whiskey lactoneFL/FR
 whiskey lactoneFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 aldehydicFR
 almondFL
 amberFR
 balsam 
 briar sweet briar eglantine 
 caramelFL
 chocolate cocoa 
 chypre 
 cinnamonFL
 clover trefle le'trefle incarnat 
 coconutFL
 fern fougere 
 hawthorn 
 hay new mown hay foin coupe 
 heather 
 lavandinFL/FR
 malt 
 oriental 
 roseFL
 spiceFL
 tobacco tabac tabaco 
 tonka 
 vanillaFL
 woodruff asperulaFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 cherry sour cherry plant
Search Trop  Picture
 clover sweet clover
Search  Picture
 clover yellow sweet clover
Search Trop  Picture
 deertongue
Search Trop  Picture
 tarragon plant
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 benzo dihydro pyrone
 benzo dihydropyrone
 benzo dihydropyrone natural
 benzo dihydropyrone synthetic
 benzodihydropyrone
1,2-benzodihydropyrone
 benzodihydropyrone FCC
 benzodihydropyrone, natural
2H-1-benzopyran-2-one, 3,4-dihydro-
 benzopyranone, dihydro-
2-oxo-chroman
oxochroman
 chroman-2-one
 chroman, 2-oxo-
2-chromanone
 coumarin, 3,4-dihydro-
 coumarin, dihydro-
 di hydro coumarin
 dihydro coumarin
3,4-dihydro-1-benzopyran-2-one
3,4-dihydro-2H-1-benzopyran-2-one
3,4-dihydro-2H-chromen-2-on
3,4-dihydro-2H,1-benzopyran-2-one
 dihydrobenzopyrone
3,4-dihydrocoumarin
 dihydrocoumarin (benzodihydropyrone)
 dihydrocoumarin FCC
 hydrocinnamic acid, o-hydroxy-, d-lactone
 hydrocoumarin
o-hydroxydihydrocinnamic acid delta-lactone
ortho-hydroxydihydrocinnamic acid delta-lactone
2-hydroxydihydrocinnamic acid lactone
 hydroxydihydrocinnamic acid lactone, o-
 melilotic acid lactone
 melilotic lactone
 melilotin
 melilotine
 melilotol
 meliotine
Synonyms   Articles   Notes   Search   Top
Articles:
Info: EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed: Tandem ruthenium-catalyzed transfer-hydrogenative cyclization/intramolecular Diels-Alder reaction of enediynes affording dihydrocoumarin-fused polycycles.
PubMed: Study of possible mechanisms involved in the inhibitory effects of coumarin derivatives on neutrophil activity.
PubMed: Effect of the nutritional supplement ALAnerv® on the serum PON1 activity in post-acute stroke patients.
PubMed: Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B.
PubMed: N-heterocyclic carbene-catalyzed [4 + 2] cycloaddition of ketenes and 3-aroylcoumarins: highly enantioselective synthesis of dihydrocoumarin-fused dihydropyranones.
PubMed: Cancer chemoprevention and nutriepigenetics: state of the art and future challenges.
PubMed: Synthesis and biological evaluation of α-methylidene-δ-lactones with 3,4-dihydrocoumarin skeleton.
PubMed: [Determination of five coumarins in toys by high performance liquid chromatography-tandem mass spectrometry].
PubMed: Novel associations of nonstructural Loci with paraoxonase activity.
PubMed: Oxidative potential of some endophytic fungi using 1-indanone as a substrate.
PubMed: Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1.
PubMed: Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process.
PubMed: An enantioselective approach toward 3,4-dihydroisocoumarin through the bromocyclization of styrene-type carboxylic acids.
PubMed: High-Density Real-Time PCR-Based in Vivo Toxicogenomic Screen to Predict Organ-Specific Toxicity.
PubMed: Asymmetric synthesis of 3,4-dihydrocoumarin motif with an all-carbon quaternary stereocenter via a Michael-acetalization sequence with bifunctional amine-thiourea organocatalysts.
PubMed: Atom arrangement strategy for designing a turn-on 1H magnetic resonance probe: a dual activatable probe for multimodal detection of hypochlorite.
PubMed: Chemical composition, anti-inflammatory, molluscicidal and free-radical scavenging activities of the leaves of Ficus radicans 'Variegata' (Moraceae).
PubMed: Development and validation of two methods based on high-performance liquid chromatography-tandem mass spectrometry for determining 1,2-benzopyrone, dihydrocoumarin, o-coumaric acid, syringaldehyde and kaurenoic acid in guaco extracts and pharmaceutical preparations.
PubMed: Coumarin metabolic routes in Aspergillus spp.
PubMed: Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role?
PubMed: Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins).
PubMed: Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity.
PubMed: Cancer chemoprevention by targeting the epigenome.
PubMed: Organocatalytic asymmetric tandem Michael addition-hemiacetalization: a route to chiral dihydrocoumarins, chromanes, and 4H-chromenes.
PubMed: A reinvestigation of the reaction of coumarins with superoxide in the liposomal bilayer: correlation between depth and reactivity.
PubMed: Lactonases with organophosphatase activity: structural and evolutionary perspectives.
PubMed: The thioesterase Bhp is involved in the formation of beta-hydroxytyrosine during balhimycin biosynthesis in Amycolatopsis balhimycina.
PubMed: Interaction between human serum esterases and environmental metal compounds.
PubMed: Determinants of variation in human serum paraoxonase activity.
PubMed: Asymmetric cycloadditions of o-quinone methides employing chiral ammonium fluoride precatalysts.
PubMed: A novel method for the synthesis of substituted 3,4-dihydrocoumarin derivatives via isocyanide-based three-component reaction.
PubMed: Synthesis, spectroscopy and alkylating properties of Pd(II) complexes of phosphorohydrazones of coumarin and chromone with potential antibacterial activity.
PubMed: Novel isocyanide-based four-component reaction: a facile synthesis of fully substituted 3,4-dihydrocoumarin derivatives.
PubMed: AlCl3-mediated direct carbon-carbon bond-forming reaction of alpha-hydroxyketene-S,S-acetals with arenes and synthesis of 3,4-disubstituted dihydrocoumarin derivatives.
PubMed: Aging and anti-aging: unexpected side effects of everyday medication through sirtuin1 modulation.
PubMed: Lack of evidence for allergenic properties of coumarin in a fragrance allergy mouse model.
PubMed: Biocatalytic production of dihydrocoumarin from coumarin by Saccharomyces cerevisiae.
PubMed: Xenobiotic reductase A in the degradation of quinoline by Pseudomonas putida 86: physiological function, structure and mechanism of 8-hydroxycoumarin reduction.
PubMed: The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.
PubMed: Isolation, structure elucidation, antioxidative and immunomodulatory properties of two novel dihydrocoumarins from Aloe vera.
PubMed: Cloning, purification, and refolding of human paraoxonase-3 expressed in Escherichia coli and its characterization.
PubMed: Cloning, high level expression of human paraoxonase-3 in Sf9 cells and pharmacological characterization of its product.
PubMed: Regioselective synthesis and estrogenicity of (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins.
PubMed: Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver.
PubMed: Chromanones and dihydrocoumarins from Calophyllum blancoi.
PubMed: Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress.
PubMed: Role of Acinetobacter calcoaceticus 3,4-dihydrocoumarin hydrolase in oxidative stress defence against peroxoacids.
PubMed: Enzymatic preparation of D-beta-acetylthioisobutyric acid and cetraxate hydrochloride using a stereo- and/or regioselective hydrolase, 3,4-dihydrocoumarin hydrolase from Acinetobacter calcoaceticus.
PubMed: Coupling of the lactone-ring conformation with crystal symmetry in 6-hydroxy-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin.
PubMed: Lactone-ring-cleaving enzymes of microorganisms: their diversity and applications.
PubMed: Purification and characterization of a novel lactonohydrolase from Agrobacterium tumefaciens.
PubMed: 3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46.
PubMed: A "cephalosporin-like" cyclic depsipeptide: synthesis and reaction with beta-lactam-recognizing enzymes.
PubMed: Selective Clara cell injury in mouse lung following acute administration of coumarin.
PubMed: Intraperitoneal administration of coumarin causes tissue-selective depletion of cytochromes P450 and cytotoxicity in the olfactory mucosa.
PubMed: Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds.
PubMed: New metabolites in the degradation of fluorene by Arthrobacter sp. strain F101.
PubMed: Natural ingredients based cosmetics. Content of selected fragrance sensitizers.
PubMed: Structure-activity relationship of coumarins in xanthine oxidase inhibition.
PubMed: HPLC analysis of tonka bean extracts.
PubMed: Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat.
PubMed: NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed: NTP Toxicology and Carcinogenesis Studies of 3,4-Dihydrocoumarin (CAS No. 119-84-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed: Structural requirements for the direct and cytochrome P450-dependent reaction of cyclic alpha,beta-unsaturated carbonyl compounds with glutathione: a study with coumarin and related compounds.
PubMed: Purification and characterization of a novel lactonohydrolase, catalyzing the hydrolysis of aldonate lactones and aromatic lactones, from Fusarium oxysporum.
PubMed: Isolation and characterization of a fluorene-degrading bacterium: identification of ring oxidation and ring fission products.
PubMed: Toxicity of coumarin and various methyl derivatives in cultures of rat hepatocytes and V79 cells.
PubMed: Anamnestic responses to contact allergens: application in the murine local lymph node assay.
PubMed: Amine prodrugs which utilize hydroxy amide lactonization. II. A potential esterase-sensitive amide prodrug.
PubMed: Acyloxybenzyl halides, inhibitors of elastases.
PubMed: A prospective toxicity evaluation (COMPACT) on 40 chemicals currently being tested by the National Toxicology Program.
PubMed: Reaction of thrombin and proteinases of the fibrinolytic system with a mechanism-based inhibitor, 3,4-dihydro-3-benzyl-6-chloromethylcoumarin.
PubMed: Studies on the mechanism of coumarin-induced toxicity in rat hepatocytes: comparison with dihydrocoumarin and other coumarin metabolites.
PubMed: Constituents of Justicia pectoralis Jacq. 2. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives.
PubMed: The sensitizing capacity of coumarins (II).
PubMed: The epicutaneous maximization test.
PubMed: Inactivation of human high- and low-molecular-weight urokinases. Analysis of their active site.
PubMed: Reactions in selected patients to 22 fragrance materials.
PubMed: Comparative study of methods chosen by the Association Française de Normalisation (AFNOR) for evaluating sensitizing potential in the albino guinea-pig.
PubMed: Degradation of 3-phenylbutyric acid by Pseudomonas sp.
PubMed: Further studies of effects of vehicles and elicitation concentration in experimental contact sensitization testing in humans.
PubMed: Physiologically active substances from marine sponges V: Isolation of physiologically active compounds from the sponge Verongia archeri.
PubMed: The metabolism of aromatic compounds in higher plants. V. Purification and properties of dihydrocoumarin hydrolase of Melilotus alba.
PubMed: [Application of Baeyer-Villiger reaction in synthesis of dihydrocoumarin].
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