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Synonyms   Articles   Notes   Search
(1aR,4S,4aS,7R,7aS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol (Click)
CAS Number: 552-02-3
ECHA EINECS - REACH Pre-Reg: 209-003-3
MDL: MFCD28899097
CoE Number: 10322
XlogP3-AA: 3.70 (est)
Molecular Weight: 222.37142000
Formula: C15 H26 O
NMR Predictor: Predict
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Flavis Number: 02.215 (Old)
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Physical Properties:
Appearance: yellow solid (est)
Assay: 50.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 75.00 °C. @ 760.00 mm Hg
Boiling Point: 293.00 to  294.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000177 mm/Hg @ 25.00 °C. (est)
Flash Point: 253.00 °F. TCC ( 123.10 °C. ) (est)
logP (o/w): 4.838 (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: herbal
Odor Strength: medium
 sweet  green  herbal  fruity  tropical  minty  
Odor Description:
at 100.00 %. 
sweet green herbal fruity tropical minty
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Penta International
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
For experimental / research use only.
Viridiflorol analytical standard
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for viridiflorol usage levels up to:
  4.0000 % in the fragrance concentrate.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 94174
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0000552023
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 552-02-3
Pubchem (cid): 94174
Pubchem (sid): 135051276
Flavornet: 552-02-3
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 acetaldehyde benzyl 2-methoxyethyl acetalFL/FR
 acetaldehyde dihexyl acetalFL/FR
 acetaldehyde methyl hexyl acetalFR
 allyl butyrateFL/FR
 allyl hexanoateFL/FR
 allyl octanoateFL/FR
 allyl propionateFL/FR
 allyl tiglateFL
isoamyl 3-methyl thiopropionateFL
 amyl butyrateFL/FR
alpha-amyl cinnamaldehyde diethyl acetalFR
alpha-amyl cinnamyl formateFL/FR
 amyl hexanoateFL/FR
isoamyl isovalerateFL/FR
isoamyl propionateFL/FR
sweet basil absoluteFL/FR
 benzyl isobutyrateFL/FR
 berry hexanoateFR
 berry pentadienoateFL/FR
 buchu mercaptanFL/FR
 butyl 2-methyl butyrateFL/FR
isobutyl angelateFL/FR
isobutyl heptanoateFL/FR
isobutyl hexanoateFL/FR
isobutyl isobutyrateFL/FR
isobutyl methyl ketoneFL/FR
isobutyl quinolineFR
2-sec-butyl thiazoleFL/FR
4-butyl thiazoleFL
 butyl valerateFL/FR
 melaleuca leucadendron var. cajuputi leaf oilFL/FR
(+)-alpha-campholenic aldehydeFL/FR
 cassis pentanoneFL/FR
 anthemis nobilis flower oil romanFL/FR
 cinnamyl formateFL/FR
 citronellyl acetateFL/FR
 citronellyl propionateFL/FR
 cognac heptanoneFL/FR
para-cresyl isobutyrateFL/FR
isocyclogeraniol (IFF)FR
 cyclohexyl carboxylic acidFL/FR
9-decenoic acidFL/FR
isodecyl acetateFR
 dihydrorose oxideFR
 anethum graveolens herb oilFL/FR
 dill weed oil reunionFL/FR
 dimethyl benzyl carbinyl butyrateFL/FR
 dimethyl benzyl carbinyl formateFL/FR
 dipentene terpene hydrocarbon byproductsFR
 dipropyl trisulfideFL
 ethyl (E,Z)-2,4-decadienoateFL/FR
 ethyl (E)-2-hexenoateFL/FR
 ethyl (E)-4-decenoateFL/FR
 ethyl 2-octenoateFL/FR
 ethyl 3-octenoateFL
 ethyl 4-pentenoateFL/FR
2-ethyl butyric acidFL/FR
 ethyl methyl-para-tolyl glycidateFL/FR
 ethyl nonanoateFL/FR
 fig leaf absoluteFL
 fir carboxylateFR
 genet absoluteFL/FR
 geranium oil africaFL/FR
 geranium oil egyptFL/FR
(E)-geranyl acetoneFL/FR
 geranyl isovalerateFL/FR
 geranyl methyl tiglate 
 geranyl propionateFL/FR
 grapefruit menthaneFL/FR
 grapefruit mercaptanFL/FR
 green dioxolaneFR
 heptanal (aldehyde C-7)FL/FR
 heptanal dimethyl acetalFL/FR
 heptyl isobutyrateFL/FR
cis-herbal cyclohexaneFR
 herbal dioxaneFR
 herbal heptaneFR
 hexanal propylene glycol acetalFL/FR
(E)-2-hexenal diethyl acetalFL
2-hexenal diethyl acetalFL
(Z)-3-hexen-1-yl (E)-2-hexenoateFL/FR
3-hexenyl 2-methyl butyrateFL/FR
(Z)-3-hexen-1-yl 2-methyl-2-pentenoateFR
(E)-2-hexen-1-yl acetateFL/FR
(Z)-3-hexen-1-yl acetateFL/FR
2-hexenyl acetateFL/FR
(Z)-3-hexen-1-yl hexanoateFL/FR
(Z)-3-hexen-1-yl isovalerateFL/FR
(Z)-3-hexen-1-yl phenyl acetateFL/FR
(E)-2-hexen-1-yl propionateFL/FR
(E)-2-hexen-1-yl valerateFL/FR
(Z)-3-hexen-1-yl valerateFL/FR
1-hexen-3-yl acetateFL
 hexyl 2-methyl butyrateFL/FR
 hexyl 2-methyl-3-pentenoateFL/FR
 hexyl butyrateFL/FR
 hexyl hexanoateFL/FR
 hexyl isobutyrateFL/FR
 hexyl isovalerateFL/FR
 hexyl pivalateFR
 hexyl propionateFL/FR
 hop absoluteFL/FR
 hop oilFL/FR
english ivy leaf absoluteFR
 jambu oleoresinFL/FR
 lily propanolFR
 linalyl formateFL/FR
 linalyl hexanoateFL/FR
 linalyl octanoateFL/FR
 lychee mercaptan acetateFL/FR
 maltyl isobutyrateFL/FR
 mango thiolFL/FR
 marigold oil mexicoFL/FR
3-mercaptohexyl acetateFL/FR
3-mercaptohexyl butyrateFL
3-mercaptohexyl hexanoateFL
 methyl 2-(methyl thio) butyrateFL
 methyl 2-hexenoateFL/FR
 methyl 2-methyl valerateFL/FR
 methyl 4-pentenoateFL
(E)-methyl geranateFL/FR
 methyl ketonesFL
 methyl nonanoateFL/FR
S-(methyl thio) hexanoateFL
 methyl thiomethyl butyrateFL
 methyl valerateFL/FR
3-methyl valeric acidFL
 neryl formateFL/FR
 nonisyl formateFR
 nonyl acetateFL/FR
1-octen-3-yl acetateFL/FR
 origanum oil greeceFL/FR
 origanum oilFL/FR
 papaya isobutyrateFL/FR
curled parsley herb oilFL/FR
 passiflora acetateFL/FR
2-pentyl cyclopentanoneFR
 phenethyl acetateFL/FR
1-phenethyl mercaptanFL
4-phenyl-2-butyl acetateFL/FR
 plum crotonateFR
 plum damasconeFR
 plum damascone (high alpha)FR
isopropyl 2-methyl butyrateFL/FR
isopropyl formateFL/FR
 propyl hexanoateFL/FR
 propyl isobutyrateFL/FR
alpha-isopropyl phenyl acetaldehydeFL/FR
2-propyl thiazoleFL
 reseda absoluteFR
 rose butanoateFL/FR
 rose pyranFR
 seaweed absolute (fucus vesiculosus et serratus)FL/FR
 sorbyl isobutyrateFL/FR
 tagete oil CO2 extractFL/FR
 tagete oil rwandaFL/FR
 tagete oil south africaFL/FR
 terpinyl propionateFL/FR
 tetrahydrofurfuryl butyrateFL/FR
 tetrahydrofurfuryl propionateFL
 thyme absoluteFL/FR
 treemoss absoluteFR
 tricyclodecyl acetateFR
S-tropical 2-thiobutyrateFL/FR
 tropical 3-thiobutyrateFL/FR
 tropical indeneFR
 tropical iononeFL/FR
2-tropical oxathianeFL/FR
 tropical thiazoleFL/FR
 tropical trithianeFL/FR
isovaleraldehyde propylene glycol acetalFL/FR
 woody acetateFR
 wormwood oil americaFL/FR
 wormwood oil cubaFL/FR
 wormwood oil italyFL/FR
 wormwood oil polandFL/FR
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 alpine bouquet 
 apple greenFR
 ash mountain ash berry 
 blossom tropical blossom 
 blue grass 
 carrot seedFL/FR
 cassis black currant budFL/FR
 chrysanthemum chrysanthemeFR
 clary sageFL/FR
 coconut tropicalFR
 elder flowerFR
 forest pine forestFR
 fruit tropical fruit 
 genet genista broomFR
 ginger whiteFR
 grass sweetFR
 hops houblonFL/FR
 lavender spikeFL/FR
 lavender waterFL/FR
 marigold tageteFL/FR
 meadow countryFR
 melissa balmFL
 passion fruitFR
 pina coladaFR
 reseda mignonetteFR
 tea blackFL
 tea china 
 tea greenFR
 tea herbalFL
 tea lemonFL
 witch hazelFR
 woodruff asperulaFR
 wormwood absinthiumFL/FR
Synonyms   Articles   Notes   Search   Top
Natural Occurrence in: note
 artemisia campestris spp. glutinosa flower oil italy @ 0.90%
Data  GC  GRIN Trop Picture
 artemisia variabilis flower oil italy @ 0.20%
Data  GC  GRIN Trop Picture
 basil flower oil sweet @ 0.02%
Data  GC  GRIN Trop Picture
 basil leaf oil sweet (ocimum basilicum) @ 0.02%
Data  GC  GRIN Trop Picture
 bergamot mint oil @ <0.1-3.0%
Data  GC  GRIN Trop Picture
 cajuput oil @ 1.3%
Data  GC  GRIN Trop Picture
 cassinia laevis flower oil australia @ 0.40%
Data  GC  GRIN Trop Picture
 cistus oil @ 4.3%
Data  GC  GRIN Trop Picture
 croton cajucara benth. leaf oil brazil @ 0.60%
Data  GC  GRIN Trop Picture
 curry wood leaf oil australia @ 0.80%
Data  GC  GRIN Trop Picture
 eucalyptus citriodora oil @ trace%
Data  GC  GRIN Trop Picture
 eucalyptus globulus bicostata oil @ 0.73%
Data  GC  GRIN Trop Picture
 eucalyptus globulus bud oil @ 0.53%
Data  GC  GRIN Trop Picture
 eucalyptus globulus fruit oil @ 2.17%
Data  GC  GRIN Trop Picture
 eucalyptus globulus maidenii f. muell oil @ 1.09%
Data  GC  GRIN Trop Picture
 eucalyptus globulus oil @ 1.12%
Data  GC  GRIN Trop Picture
 eucalyptus globulus oil rwanda @ 0.03%
Data  GC  GRIN Trop Picture
 eucalyptus globulus oil zambia @ 0.50%
Data  GC  GRIN Trop Picture
 eucalyptus globulus pseudoglobulus oil @ 0.13%
Data  GC  GRIN Trop Picture
 glycosmis pentaphylla (cor.) bark oil india @ 0.20%
Data  GC  GRIN Trop Picture
 himantandra baccata
GRIN Trop Picture
 labdanum leaf oil @ 11.80%
Data  GC  GRIN Trop Picture
 labdanum oil @ 12.81%
Data  GC  GRIN Trop Picture
 laurel leaf oil turkey @ 0.30%
Data  GC  GRIN Trop Picture
 lemon verbena oil morocco @ 0.1%
Data  GC  GRIN Trop Picture
 lemon verbena oil turkey @ 0.08%
Data  GC  GRIN Trop Picture
 lime oil expressed florida @ trace%
Data  GC  GRIN Trop Picture
 manuka var. eximium oil australia @ 4.30%
Data  GC  GRIN Trop Picture
 manuka var. rotundifolium oil australia @ 2.00%
Data  GC  GRIN Trop Picture
 manuka var. scoparium oil new zealand @ 0.46%
Data  GC  GRIN Trop Picture
 marjoram oil spain @ 0.35%
Data  GC  GRIN Trop Picture
 marsypianthes chamaedrys (vahl) kuntze oil brazil @ 0.60%
Data  GC  GRIN Trop Picture
 melaleuca viridiflora
GRIN Trop Picture
 myrtle lemon scented leaf oil australia @ 2.30%
Data  GC  GRIN Trop Picture
 peppermint oil america @ 0.15%
Data  GC  GRIN Trop Picture
 peppermint oil mongolia @ 0.09%
Data  GC  GRIN Trop Picture
 phoebe oil brazil @ 1.19%
Data  GC  GRIN Trop Picture
 polyalthia australis (benth.) jessup leaf oil australia @ 1.10%
Data  GC  GRIN Trop Picture
 sage oil albania @ 4.60%
Data  GC  GRIN Trop Picture
 sage oil cuba @ 13.46%
Data  GC  GRIN Trop Picture
 sage oil hydrodistillation france @ 0.60%
Data  GC  GRIN Trop Picture
 sage oil lithuania @ 4.58%
Data  GC  GRIN Trop Picture
 sage oil reunion @ 1.70%
Data  GC  GRIN Trop Picture
 satureja viminea l. oil costa rica @ trace%
Data  GC  GRIN Trop Picture
 sundacarpus amarus (blume) c.n. page leaf oil australia @ 0.30%
Data  GC  GRIN Trop Picture
 tansy oil canada @ 0.20%
Data  GC  GRIN Trop Picture
 tea tree oil australia @ 0.58%
Data  GC  GRIN Trop Picture
 thyme oil portuguese @ 0.1%
Data  GC  GRIN Trop Picture
 thyme oil spain @ 0.08%
Data  GC  GRIN Trop Picture
 witch hazel leaf oil @ 0.21%
Data  GC  GRIN Trop Picture
 zanthoxylum bracchyacanthum l. leaf oil australia @ 0.50%
Data  GC  GRIN Trop Picture
 zanthoxylum ovalifolium l. leaf oil australia @ 0.40%
Data  GC  GRIN Trop Picture
Synonyms   Articles   Notes   Search   Top
 decahydro-1,1,4,7-tetramethyl-, (1ar,4S,4as,7R,7as,7bs)-1H-cycloprop(e)azulen-4-ol
(1aR- (1aalpha,4beta,4abeta, 7alpha,7abeta,7balpha))-decahydro-1,1,4,7-tetramethyl-1H-cycloprop(e)azulen-4-ol
 viridiflorol natural
 viridiflorol synthetic
Synonyms   Articles   Notes   Search   Top
PubMed: Antibacterial, allelopathic and antioxidant activities of essential oil of Salvia officinalis L. growing wild in the Atlas Mountains of Morocco.
PubMed: Bioactive constituents of Homalomena aromatica essential oil and its antifungal activity against dermatophytes and yeasts.
PubMed: Chemotaxonomical markers in essential oil of Murraya koenigii.
PubMed: Variation of chemical composition of essential oils in wild populations of Thymus algeriensis Boiss. et Reut., a North African endemic species.
PubMed: Composition of the essential oil of Pogostemon travancoricus var. travancoricus.
PubMed: Sedative effects of essential oils obtained from Baccharis uncinella.
PubMed: Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer L. population from Spain.
PubMed: Histochemical investigation of Cochlospermum regium (Schrank) Pilg. leaves and chemical composition of its essential oil.
PubMed: Chemotype diversity of indigenous Dalmatian sage (Salvia officinalis L.) populations in Montenegro.
PubMed: Chemical composition and free radical scavenging activity of the essential oil of Achillea ligustica growing wild in Lipari (Aeolian Islands, Sicily).
PubMed: Chemical analysis and antioxidant activity of the essential oils of three Piperaceae species growing in the central region of Cuba.
PubMed: Genotoxic effects of Campomanesia xanthocarpa extracts on Allium cepa vegetal system.
PubMed: Comparison of different extraction methods for the determination of α- and β-thujone in sage (Salvia officinalis L.) herbal tea.
PubMed: A comparative analysis of essential oils of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. from Vietnam.
PubMed: New flavan and alkyl alpha,beta-lactones from the stem bark of Horsfieldia superba.
PubMed: Volatile organic compounds of conspecific-damaged Eucalyptus benthamii influence responses of mated females of Thaumastocoris peregrinus.
PubMed: Chemotaxonomical markers in essential oil of Murraya koenigii.
PubMed: Propolis volatiles characterisation from acaricide-treated and -untreated beehives maintained at Algarve (Portugal).
PubMed: Composition of the essential oil of Pogostemon travancoricus var. travancoricus.
PubMed: Correlation between chemical composition and antibacterial activity of essential oils from fifteen Eucalyptus species growing in the Korbous and Jbel Abderrahman arboreta (North East Tunisia).
PubMed: Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer L. population from Spain.
PubMed: Chemical diversity in the essential oil of Indian valerian (Valeriana jatamansi Jones).
PubMed: Essential oil composition of Eucalyptus procera Dehnh. leaves from central Iran.
PubMed: Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties.
PubMed: Comparison of Eucalyptus cinerea essential oils produced by hydrodistillation and supercritical carbon dioxide extraction.
PubMed: Variation in volatile leaf oils of five Eucalyptus species harvested from Jbel Abderrahman arboreta (Tunisia).
PubMed: Chemical composition, seasonal variation, and biosynthetic considerations of essential oils from Baccharis microdonta and B. elaeagnoides (Asteraceae).
PubMed: Microdistillation and analysis of volatiles from eight ornamental Salvia taxa.
PubMed: Potential interaction between the volatile and non-volatile fractions on the in vitro antimicrobial activity of three South African Pelargonium (Geraniaceae) species.
PubMed: Phytochemical analysis and in vitro free-radical-scavenging activities of the essential oils from leaf and fruit of Melaleuca leucadendra L.
PubMed: Influence of ionic interactions on essential oil and phenolic diterpene composition of Dalmatian sage (Salvia officinalis L.).
PubMed: Seasonal variation, chemical composition, and analgesic and antimicrobial activities of the essential oil from leaves of Tetradenia riparia (Hochst.) Codd in southern Brazil.
PubMed: Chemical composition of the essential oil of Salvia officinalis L. from Romania.
PubMed: Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.).
PubMed: Variation in volatile leaf oils of eleven eucalyptus species harvested from korbous arboreta (Tunisia).
PubMed: Chemical compositions, antifungal and antioxidant activities of essential oil and various extracts of Melodorum fruticosum L. flowers.
PubMed: The molecular basis of host plant selection in Melaleuca quinquenervia by a successful biological control agent.
PubMed: Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol.
PubMed: Variation in volatile leaf oils of 13 Eucalyptus species harvested from Souinet arboreta (Tunisia).
PubMed: Variations in essential oil, phenolic compounds, and antioxidant activity of tunisian cultivated Salvia officinalis L.
PubMed: Chemical composition and antimicrobial activity of the essential oils of Lavandula stoechas L. ssp. stoechas growing wild in Turkey.
PubMed: Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: ideal candidate for anti-cariogenic formulations.
PubMed: Chemical composition and antibacterial activity of essential oils of Eugenia species.
PubMed: Silvaglins and related 2,3-secodammarane derivatives - unusual types of triterpenes from Aglaia silvestris.
PubMed: [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood].
PubMed: Seasonal variation of the chemical constituents of the essential oil of Santolina etrusca from Italy.
PubMed: Composition of the essential oil of Salvia officinalis L. from various European countries.
PubMed: Volatile constituents of Vitex negundo leaves.
PubMed: Sesquiterpenes, limonoid and coumarin from the wood bark of Guarea guidonia.
PubMed: Chemical composition and antioxidant, antimicrobial, and antifungal activities of the essential oil of Achillea ligustica all.
PubMed: Bioactivity guided isolation of antifungal compounds from the liverwort Bazzania trilobata (L.) S.F. Gray.
PubMed: Essential oils from the leaves of three New Zealand species of Pseudopanax (Araliaceae).
PubMed: Effect of nitrogen concentration of the nutrient solution on the volatile constituents of leaves of Salvia fruticosa Mill. in solution culture.
PubMed: Dietary influences on terpenoids sequestered by the biological control agent Oxyops vitiosa: effect of plant volatiles from different Melaleuca quinquenervia chemotypes and laboratory host species.
PubMed: Phytotoxicity and volatile constituents from leaves of Callicarpa japonica Thunb.
PubMed: Antipredator defense of biological control agent Oxyops vitiosa is mediated by plant volatiles sequestered from the host plant Melaleuca quinquenervia.
PubMed: Organ- and season-dependent variation in the essential oil composition of Salvia officinalis L. cultivated at two different sites.
PubMed: Chemical, physical and antimicrobial properties of essential oils of Leptospermum scoparium and Kunzea ericoides.
PubMed: A New Norlupene from the Leaves of Melaleuca leucadendron
PubMed: Composition and antimicrobial activity of the essential oil of Cistus creticus subsp. eriocephalus.
PubMed: Sesquiterpene Glycosides from Calendula persica.
PubMed: [The ocurrence of Viridiflorol in Salvia officinalis.].
Synonyms   Articles   Notes   Search   Top
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Soluble in:
 water, 11.98 mg/L @ 25 °C (est)
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