rue oil
volatile oil distilled from the herb rue, ruta graveolens l., rutaceae

Sponsors

Name: ruta graveolens l. oil
CAS Number: 8014-29-7
FDA UNII: VDI0O08XRA
Also Contains: ruta graveolens herb extract
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1699 Oil of Rue View-review
FEMA Number: 2995 rue oil
FDA Mainterm: RUE, OIL (RUTA GRAVEOLENS L.)
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1699 Oil of rue.
 
Physical Properties:
Appearance: orange yellow clear liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
 water, 19.71 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: herbal
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 sharp herbal fruity orange acidic
Odor Description:
at 10.00 % in dipropylene glycol.
sharp herbal fruity orange acrid
Luebke, William tgsc, (1991)
Flavor Type: herbal
 rue
Taste Description:
rue
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
 
Suppliers:
Berjé
Rue Oil
Happening at Berje
Bontoux
RUE OIL
Bristol Botanicals
Rue essential oil Ruta graveolens, France
Ernesto Ventós
RUE OIL
Odor: HERBACEOUS, WILD
Flavor: SHARP, BURNING, ACRID TASTE
Hermitage Oils
Rue Essential Oil WILD CRAFTED
Odor: characteristic
Use: Adam Michael has this to say “Rue grows freely throughout Southern Europe and especially in the Mediterranean region. In this instance our material is wild grown in Spain. The plant itself is aesthetically pleasing on the eye, comprising of little lobe green shape leaves with a creamy white hue present in the spring and fading off by early summer. By summer we are greeted with clusters of small, rich yellow flowers, comprising of about 4-5 petals per flower.
The Vault
Indukern F&F
RUE OIL
Odor: HERBAL, FRUITY
Jiangyin Healthway
Rue Oil
New functional food ingredients
Liberty Natural Products
RUE SPAIN
Lluch Essence
RUE OIL
Penta International
RUE OIL, Kosher
Reincke & Fichtner
Rue Oil organic + NOP
Reincke & Fichtner
Rue Oil
The John D. Walsh Company
Rue Oil, Spanish
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975.

oral-mouse LD50 2070 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Phototoxicity
IFRA fragrance material specification:
 Where the bergapten (5-methoxypsoralen) content of all relevant oils present in a compound has been determined, it is recommended that for applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, the total level of bergapten in the consumer products should not exceed 0.0015% (15 ppm). This is equivalent to 0.0075% (75 ppm) in a fragrance compound used at 20% in the consumer product. Where the level of bergapten has not been determined by appropriate methods, the limits specified in the guidelines on individual oils should apply. In those cases, where such oils are used in combination with other phototoxic ingredients, the additive effect has to be taken into consideration and the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100.
IFRA: View Standard
limits in the finished product for - "leave on the skin contact":
  0.1500 % Restriction.
Recommendation for rue oil usage levels up to:
  2.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -3.30000
beverages(nonalcoholic): -1.20000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -1.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.30000
fruit ices: -1.30000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -4.10000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
ClinicalTrials.gov: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 8014-29-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 ruta graveolens l. oil
Chemidplus: 0008014297
 
References:
 ruta graveolens l. oil
Canada Domestic Sub. List: 8014-29-7
Pubchem (sid): 135297220
 
Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.29.6000
Typical G.C.
Wikipedia: View
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
 
Potential Blenders and core components note
For Odor
acidic
2-
ethyl butyric acid
FL/FR
anisic
amyl furoate
FL/FR
caramellic
diethyl malate
FL/FR
ethereal
ethyl 4-pentenoate
FL/FR
fatty
2-
decen-1-ol
FL/FR
floral
iso
amyl angelate
FL/FR
alpha-
amyl cinnamaldehyde
FL/FR
benzyl acetone
FL/FR
butyl tiglate
FR
cassis cyclohexene
FR
dimethyl benzyl carbinyl butyrate
FL/FR
geranyl tiglate
FL/FR
jasmin absolute egypt (from concrete)
FL/FR
menthadienyl formate
FR
methyl benzyl acetate (mixed ortho-,meta-,para-)
FL/FR
nerolin fragarol
FL/FR
nonan-3-yl acetate
FL/FR
3-
nonanone
FL/FR
rose undecene
FR
fruity
para-
anisyl propionate
FL/FR
balsam specialty
FR
hexanal propylene glycol acetal
FL/FR
para-
menth-1-ene-9-ol
FL/FR
2-
methyl butyl isovalerate
FL/FR
methyl dimethyl anthranilate
FL/FR
2-
undecanone
FL/FR
2-
undecenal
FL/FR
green
butyl heptanoate
FL/FR
iso
butyl heptanoate
FL/FR
iso
butyl methyl ketone
FL/FR
dicyclopentadiene propionate
FR
herbal cyclohexane
FR
hexyl tiglate
FL/FR
magnolia flower oil CO2 extract
FL/FR
herbal
iso
amyl heptanoate
FL/FR
artemisia ludoviciana oil
FR
buchu mercaptan acetate
FL/FR
butyl levulinate
FL/FR
chamomile propionate
FR
chamomile valerate
FR
cuminyl acetate
FL/FR
dimethyl benzyl carbinyl crotonate
FL/FR
linalyl formate
FL/FR
linalyl octanoate
FL/FR
1-para-
menthen-9-yl acetate
FL/FR
methyl hexyl ether
FL/FR
(1S,5R)-
myrtenyl acetate
FL/FR
myrtle oil
FL/FR
3-
octanon-1-ol
FL/FR
rue oil cuba
FL/FR
ruta graveolens herb extract
FR
ruta graveolens herb tincture
FR
ruta graveolens leaf extract
FL/FR
tagete oil CO2 extract
FL/FR
tagete oil egypt
FL/FR
tagete oil rwanda
FL/FR
tagete oil south africa
FL/FR
tagete oil turkey
FL/FR
tagete oil zambia
FL/FR
tricyclodecenyl isobutyrate
FR
tricyclodecenyl propionate
FR
viridiflorol
FL/FR
medicinal
meta-
dimethyl hydroquinone
FL/FR
orris
orris capronate
FL/FR
woody
2-
decalinyl acetate
FR
patchouli absolute
FR
For Flavor
No flavor group found for these
iso
amyl angelate
FL/FR
amyl furoate
FL/FR
para-
anisyl propionate
FL/FR
benzyl methyl tiglate
FL
iso
butyl heptanoate
FL/FR
cuminyl acetate
FL/FR
diethyl malate
FL/FR
(±)-(cis+trans)-1,2-
dihydroperillaldehyde
FL
dimethyl benzyl carbinyl crotonate
FL/FR
ethyl 4-pentenoate
FL/FR
linalyl formate
FL/FR
magnolia flower oil CO2 extract
FL/FR
methyl benzyl acetate (mixed ortho-,meta-,para-)
FL/FR
methyl dimethyl anthranilate
FL/FR
nonan-3-yl acetate
FL/FR
3-
octanon-1-ol
FL/FR
viridiflorol
FL/FR
althaea officinalis root tincture
FL
acidic
acidic
2-
ethyl butyric acid
FL/FR
(E)-2-
hexenoic acid
FL
chemical
meta-
dimethyl hydroquinone
FL/FR
creamy
althaea officinalis root extract
FL
ethereal
methyl hexyl ether
FL/FR
floral
dimethyl benzyl carbinyl butyrate
FL/FR
geranyl tiglate
FL/FR
jasmin absolute egypt (from concrete)
FL/FR
fruity
benzyl acetone
FL/FR
buchu mercaptan acetate
FL/FR
butyl heptanoate
FL/FR
hexanal propylene glycol acetal
FL/FR
linalyl octanoate
FL/FR
1-para-
menthen-9-yl acetate
FL/FR
2-
methyl butyl isovalerate
FL/FR
nerolin fragarol
FL/FR
tagete oil CO2 extract
FL/FR
tagete oil rwanda
FL/FR
tagete oil south africa
FL/FR
tagete oil turkey
FL/FR
tagete oil zambia
FL/FR
green
iso
butyl methyl ketone
FL/FR
hexyl tiglate
FL/FR
3-
nonanone
FL/FR
herbal
iso
amyl heptanoate
FL/FR
butyl levulinate
FL/FR
para-
menth-1-ene-9-ol
FL/FR
rue herb
FL
rue oil cuba
FL/FR
ruta graveolens leaf extract
FL/FR
tagete oil egypt
FL/FR
orris
orris capronate
FL/FR
pungent
acetaldehyde
FL
sour
2,4-
dimethyl-2-pentenoic acid
FL
spicy
myrtle oil
FL/FR
tropical
alpha-
amyl cinnamaldehyde
FL/FR
waxy
2-
decen-1-ol
FL/FR
2-
undecanone
FL/FR
2-
undecenal
FL/FR
woody
(1S,5R)-
myrtenyl acetate
FL/FR
 
Potential Uses:
 citrusFR
 herbalFR
 
Occurrence (nature, food, other): note
 rue
Search Trop Picture
 
Synonyms:
 herb-of-grace oil
 rue oil
 rue oil, spanish
 ruta graveolens oil
 ruta hortensis oil
 volatile oil distilled from the herb rue, ruta graveolens l., rutaceae
 

Articles:

PubMed: [The fatty acid composition of Ruta graveolens seed oil and its byological activity].
PubMed: Identity and pharmacognosy of Ruta graveolens Linn.
PubMed: Chemical composition and antimicrobial activity of the essential oils from four Ruta species growing in Algeria.
PubMed: Repellent activity of plant-derived compounds against Amblyomma cajennense (Acari: Ixodidae) nymphs.
PubMed: In vitro antimicrobial activity of plants in Acute Otitis Externa.
PubMed: Potential allelochemicals from the essential oil of Ruta graveolens.
PubMed: Saprophytic and cycloheximide resistant fungi isolated from golden hamster.
PubMed: [The volatile oil of tissue cultures of Ruta graveolens L. I. The composition of the coil (author's transl)].
PubMed: [Volatile oil from Ruta graveolens L. II. Geijerene, principle component of the root oil].
PubMed: [The essential oil of Ruta graveolens L. I].
PubMed: [Investigations on the content of oil in various organs of Ruta graveolens L. subsp. hortensis (Miller) Gams. during 1 year of its growth].
 
Notes:
Rue Oil is steam distilled from freshly harvested, blooming or fruit bearing, wild growing plants of Ruta Montana, cultivated plants of Ruta Graveolens, or other species of Ruta. The plants are natives of the Mediterranean countries and they grow wild in Spain, Morocco, Corsica, Sardinia and Algeria. Cultivation also takes place in France and Spain, to a small degree in Italy and Yugoslavia. Spain is the largest producer of rue oil. tsca definition 2008: extractives and their physically modified derivatives. ruta graveolens, rutaceae.
 
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