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cubeb oil
essential oil obtained from the unripe fermented ripe fruits of the tailed pepper, piper cubeba l., piperaceae

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Flavor Demo Formulas
Name:piper cubeba fruit oil
CAS Number: 8007-87-2
FDA UNII:HDE20IN4M5
CoE Number:131
Also Contains:cinnamomum cassia leaf extract
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm: CUBEB, OIL (PIPER CUBEBA L. F.)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
 
Physical Properties:
Appearance:pale yellow to bluish green clear liquid (est)
Food Chemicals Codex Listed: No
Optical Rotation:-12.00 to -43.00
Acid Value: 2.00 max. KOH/g
Flash Point: 180.00 °F. TCC ( 82.22 °C. )
Soluble in:
 alcohol
 water, 4.581 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: spicy
Odor Strength:medium ,
recommend smelling in a 10.00 % solution or less
Substantivity:268 hour(s) at 100.00 %
fresh spicy bois de rose herbal smoky
Odor Description:at 10.00 % in dipropylene glycol. fresh spicy bois de rose herbal smokey
Luebke, William tgsc, (1986)
Odor sample from: Bush Boake Allen Inc
Flavor Type: spicy
">cubeb
Taste Description: cubeb
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Berjé
Cubeb Oil
Happening at Berje
Blue Pacific Flavors
Cubeb Oil
Bristol Botanicals
Cubebs essential oil Piper cubeba, Indonesia
Ernesto Ventós
CUBEB OIL 851 INDESSO
Odor: MINT- LIKE, SPICY
Hermitage Oils
Cubeb Essential Oil
Odor: characteristic
Use: Adam Michael has this to say “Indonesian cubeb, distilled from the unripe berries from the fruit tree. The smell is warming with similarities to black pepper and similar therapeutic uses as well. Diluted down heavily in carrier oil, cubeb can be considered useful for treating flatulence, aiding digestion and easing general muscle aches. The natural chemistry comprises mainly of alpha- & beta cubebene, cubebol, alpha-copaene, delta-cadinene, sabinene.”
The Vault
Jiangyin Healthway
Cubeb Oil
New functional food ingredients
Liberty Natural Products
CUBEB INDONESIA
Lluch Essence
CUBEB OIL
Moellhausen
CUBEB EO
Odor: citric, fresh, characteristic of orange peel
Flavor: terpenic, aromatic, spicy, pepper note
Noble Molecular Research
For experimental / research use only.
Cubeb Oil
Penta International
CUBEB OIL FCC, NATURAL, Kosher
Reincke & Fichtner
Cubeb Oil organic + NOP
Reincke & Fichtner
Cubeb Oil
Ultra International
Cubeb Oil
Crop Calendar
White Lotus Aromatics
Cubeb essential oil
Odor: fresh, warm spicy-peppery, camphoraceous bouquet with dry woody undertone
Use: In natural perfumes used in culinary bases, spice accords, incense bouquets, apothecary blends.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for cubeb oil usage levels up to:
  1.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -4.60000
beverages(nonalcoholic): -2.40000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -33.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.25000
fruit ices: -0.25000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -1.80000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 25.0000030.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):8007-87-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
piper cubeba fruit oil
Chemidplus:0008007872
 
References:
 piper cubeba fruit oil
Canada Domestic Sub. List:8007-87-2
Pubchem (sid):135274884
 
Other Information:
FDA Everything Added to Food in the United States (EAFUS):View
Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
 
Potential Blenders and core components note
For Odor
No odor group found for these
para-
menth-1-en-9-al
FL/FR
aldehydic
aldehydic
agrumen nitrile
FR
balsamic
amyris wood oil
FL/FR
cheesy
2-
heptanone
FL/FR
earthy
3-
octen-2-one
FL/FR
octyl phenyl acetate
FL/FR
floral
bois de rose oil brazil
FL/FR
coranol (Firmenich)
FR
coriander seed oil
FL/FR
dihydrojasmone
FL/FR
dihydrolinalool
FL/FR
3,6-
dimethyl-3-octanol
FL/FR
ethyl linalool
FR
ethyl linalyl acetal
FR
ethyl linalyl acetate
FR
ethyl linalyl ether
FL/FR
ho leaf oil
FR
ho wood oil
FR
dextro-
linalool
FL/FR
linalool
FL/FR
laevo-
linalool
FL/FR
linalool oxide
FL/FR
linalyl anthranilate
FL/FR
terpinyl isobutyrate
FL/FR
tetrahydrolinalool
FL/FR
fruity
perillyl acetate
FL/FR
green
sec-
butyl-3-methyl but-2-ene thioate
FL/FR
carrot leaf oil (daucus carota ssp.maximus)
FR
privet dioxane
FR
herbal
carvacryl methyl ether
FL/FR
coriander oleoresin
FL/FR
coriander seed absolute
FL/FR
dehydroxylinalool oxide
FL/FR
herbal acetal
FR
lavender specialty
FR
1-para-
menthen-9-yl acetate
FL/FR
T-
muurolol
FL/FR
3-
nonanol
FL/FR
3-
octanon-1-ol
FL/FR
curled
parsley seed oil
FL/FR
saffron indenone
FL/FR
safranal
FL/FR
thymyl methyl ether
FL/FR
leathery
black
tea leaf absolute
FL/FR
minty
betula lenta bark oil america
FL/FR
spicy
anona squamosa leaf oil
FR
iso
butyl (E,E)-2,4-decadienamide
FL/FR
carrot weed oil
FL/FR
carvacryl ethyl ether
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
cubeb oil CO2 extract (piper cubeba)
FL/FR
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
ginger oleoresin africa
FL/FR
origanum majorana oil
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
woody
cedrela wood oil
FR
louro brasileiro wood oil
FR
patchouli absolute
FR
xanthoxylum alatum roxb. oil
FR
For Flavor
No flavor group found for these
iso
butyl (E,E)-2,4-decadienamide
FL/FR
sec-
butyl-3-methyl but-2-ene thioate
FL/FR
carvacryl ethyl ether
FL/FR
carvacryl methyl ether
FL/FR
2,4-
dimethyl anisole
FL
ethyl linalyl ether
FL/FR
dextro-
linalool
FL/FR
para-
menth-1-en-9-al
FL/FR
T-
muurolol
FL/FR
3-
nonanol
FL/FR
3-
octanon-1-ol
FL/FR
octyl phenyl acetate
FL/FR
terpinyl isobutyrate
FL/FR
hexyl 3-mercaptobutanoate
FL
berry
berry
perillyl acetate
FL/FR
cheesy
2-
heptanone
FL/FR
citrus
linalool
FL/FR
laevo-
linalool
FL/FR
creamy
3-
octen-2-one
FL/FR
floral
bois de rose oil brazil
FL/FR
dihydrojasmone
FL/FR
dihydrolinalool
FL/FR
linalyl anthranilate
FL/FR
tetrahydrolinalool
FL/FR
fruity
1-para-
menthen-9-yl acetate
FL/FR
green
carrot weed oil
FL/FR
coriander oleoresin
FL/FR
linalool oxide
FL/FR
herbal
coriander seed absolute
FL/FR
coriander seed oil
FL/FR
3,6-
dimethyl-3-octanol
FL/FR
origanum majorana oil
FL/FR
curled
parsley seed oil
FL/FR
saffron indenone
FL/FR
minty
betula lenta bark oil america
FL/FR
musty
thymyl methyl ether
FL/FR
peppery
cubeb distillates
FL
spicy
cinnamaldehyde dimethyl acetal
FL/FR
cubeb fruit
FL
cubeb oil CO2 extract (piper cubeba)
FL/FR
cubeb oleoresin
FL
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
ginger oleoresin africa
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
tea
black
tea leaf absolute
FL/FR
woody
amyris wood oil
FL/FR
dehydroxylinalool oxide
FL/FR
safranal
FL/FR
 
Potential Uses:
FRcarnation dianthus oeillet
 pepper
FL/FRpepper tree
FRspice
FRwoody
 
Occurrence (nature, food, other):note
 cubeb
Search Trop Picture
 
Synonyms:
 cubeb EO
 cubeb oil
 cubeb oil FCC
 essential oil obtained from the unripe fermented ripe fruits of the tailed pepper, piper cubeba l., piperaceae
 piper cubeba fruit oil
 

Articles:

PubMed:Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives.
PubMed:Evaluation of lignan (-)-cubebin extracted from Piper cubeba on human colon adenocarcinoma cells (HT29).
PubMed:Cytotoxic activity of Piper cubeba extract in breast cancer cell lines.
PubMed:Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model.
PubMed:Biological activities of Zingiber officinale (Zingiberaceae) and Piper cubeba (Piperaceae) essential oils against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae).
PubMed:In vitro antiparasitic activity and chemical composition of the essential oil obtained from the fruits of Piper cubeba.
PubMed:Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
PubMed:A comparative study of the modulatory effects of (-)-cubebin on the mutagenicity/recombinogenicity induced by different chemical agents.
PubMed:The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta.
PubMed:Mutagenicity and antimutagenicity of (-)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays.
PubMed:Nephroprotective effect of Kabab chini (Piper cubeba) in gentamycin-induced nephrotoxicity.
PubMed:Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
PubMed:Identification of ambiguous cubeb fruit by DART-MS-based fingerprinting combined with principal component analysis.
PubMed:Essential and toxic elements in three Pakistan's medicinal fruits (Punica granatum, Ziziphus jujuba and Piper cubeba) analysed by INAA.
PubMed:In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni.
PubMed:Radical scavenging ability of some compounds isolated from Piper cubeba towards free radicals.
PubMed:Was the famous astronomer Copernicus also a nephrologist.
PubMed:The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster.
PubMed:Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts.
PubMed:Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh.
PubMed:Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties.
PubMed:Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth?
PubMed:Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens.
PubMed:(-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats.
PubMed:Effect of some medicinal plants on plasma antioxidant system and lipid levels in rats.
PubMed:Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition.
PubMed:Potent CYP3A4 inhibitory constituents of Piper cubeba.
PubMed:Enzymatic and non-enzymatic antioxidants in selected Piper species.
PubMed:Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis angulata and Rosa hybrida.
PubMed:Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.
PubMed:[Constituents of Aristolochia triangularis].
PubMed:Comparison of vegetative anatomy of piperales. I. Juvenile xylem of twigs.
PubMed:The occurrence of mature fruits of Piper cubeba in recently imported cubeb.
PubMed:The problem of foreign botanicals.
 
Notes:
Steam distilled from the unripe, dried, crushed fruit of Piper Cubeba cultivated in Sunda Islands and Ceylon. tsca definition 2008: extractives and their physically modified derivatives. piper cubeba, piperaceae.
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