ocimum basilicum leaf oil
sweet basil leaf oil
solvent for dyes in staining. tsca definition 2008: extractives and their physically modified derivatives. ocimum basilicum, labiatae.
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Name: ocimum basilicum l. herb oil
CAS Number: 8015-73-4 
MDL: MFCD00217166
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2119  sweet basil leaf oil
FDA Regulation:
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 water, 332.1 mg/L @ 25 °C (est)
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Organoleptic Properties:
Odor Type: licorice
Odor Strength: medium
 basil  herbal  tarragon  
Odor Description:
at 100.00 %. 
 basil  licorice  tarragon  
Taste Description:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
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Golden Frog Trading Manufacturing
Basil Leaf Oil
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  1400 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 867, 1973.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 867, 1973.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Sensitization
IFRA fragrance material specification:
 Linalool and natural products known to be rich in linalool, such as bois de rose, coriander or ho wood oil, should only be used when the level of peroxides is kept to the lowest practical level. It is recommended to add antioxidants at the time of production of the raw material. The addition of 0.1% BHT or alpha-tocopherol for example has shown great efficiency. The maximum peroxide level for products in use should be 20 mmol/l.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
estragol Max. Found: <92.00 % and Reason: Carcinogenicity
eugenol Max. Found: <4.00 % and Reason: Sensitization
methyl eugenol Max. Found: <6.00 % and Reason: Potential carcinogenic activity in animals
IFRA: View Standard
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -4.20000
beverages(nonalcoholic): -2.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -15.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -2.70000
fruit ices: -2.70000
gelatins / puddings: -0.01000
granulated sugar: --
gravies: --
hard candy: -6.20000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -24.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 8015-73-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 ocimum basilicum l. herb oil
Chemidplus: 0008015734
RTECS: CR3325000 for cas# 8015-73-4
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 ocimum basilicum l. herb oil
Canada Domestic Sub. List: 8015-73-4
Pubchem (sid): 135362711
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
 Typical G.C.
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
None Found
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Potential Uses:
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Occurrence (nature, food, other): note
 basil leaf
Search Trop  Picture
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sweet basil leaf oil
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PubMed: Oral supplementation of Ocimum basilicum has the potential to improves the locomotory, exploratory, anxiolytic behavior and learning in adult male albino mice.
PubMed: The effects of different UV-B radiation intensities on morphological and biochemical characteristics in Ocimum basilicum L.
PubMed: Variation in essential oil composition within individual leaves of sweet basil (Ocimum basilicum L.) is more affected by leaf position than by leaf age.
PubMed: Chemical composition and larvicidal activity of essential oil from Ocimum basilicum (L.) against Culex tritaeniorhynchus, Aedes albopictus and Anopheles subpictus (Diptera: Culicidae).
PubMed: Mosquitocidal and antiplasmodial activity of Senna occidentalis (Cassiae) and Ocimum basilicum (Lamiaceae) from Maruthamalai hills against Anopheles stephensi and Plasmodium falciparum.
PubMed: Stomatal density and metabolic determinants mediate salt stress adaptation and water use efficiency in basil (Ocimum basilicum L.).
PubMed: Effect of Methanolic Leaf Extract of Ocimum basilicum L. on Benzene-Induced Hematotoxicity in Mice.
PubMed: Photoprotection by foliar anthocyanins mitigates effects of boron toxicity in sweet basil (Ocimum basilicum).
PubMed: Aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats.
PubMed: Partial defoliation and hydraulic integration in Ocimum basilicum (Lamiaceae): testing a model for sectored xylem flow using ¹⁵N labeling.
PubMed: Characterisation of organic and conventional sweet basil leaves using chromatographic and flow-injection mass spectrometric (FIMS) fingerprints combined with principal component analysis.
PubMed: Effect of climate change on Alternaria leaf spot of rocket salad and black spot of basil under controlled environment.
PubMed: Phenylpropanoid biosynthesis in leaves and glandular trichomes of basil (Ocimum basilicum L.).
PubMed: Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh.
PubMed: Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis.
PubMed: Ocimum basilicum L.: phenolic profile and antioxidant-related activity.
PubMed: Somatic embryogenesis and plant regeneration from leaf callus of Ocimum basilicum L.
PubMed: Light suppresses sporulation and epidemics of Peronospora belbahrii.
PubMed: Epidermal coumaroyl anthocyanins protect sweet basil against excess light stress: multiple consequences of light attenuation.
PubMed: Evaluation of antileishmanial activity of South Indian medicinal plants against Leishmania donovani.
PubMed: Root internalization, transport and in-planta survival of Salmonella enterica serovar Newport in sweet basil.
PubMed: Anthocyanin inheritance and instability in purple basil (Ocimum basilicum L.).
PubMed: In vitro rosmarinic acid accumulation in sweet basil (Ocimum basilicum L.).
PubMed: Light reflected from colored mulches affects aroma and phenol content of sweet basil (Ocimum basilicum L.) leaves.
PubMed: Effects of three AM fungi on growth, distribution of glandular hairs, and essential oil production in Ocimum basilicum L. var. Genovese.
PubMed: Scale-up micropropagation of sweet basil (Ocimum basilicum L.) in an airlift bioreactor and accumulation of rosmarinic acid.
PubMed: Chemical characterization of basil (Ocimum basilicum L.) found in local accessions and used in traditional medicines in Iran.
PubMed: 4-coumarate: CoA ligase partitions metabolites for eugenol biosynthesis.
PubMed: Deployment of municipal solid wastes as a substitute growing medium component in marigold and basil seedlings production.
PubMed: In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum.
PubMed: Use of a common laboratory glassware detergent improves recovery of Cryptosporidium parvum and Cyclospora cayetanensis from lettuce, herbs and raspberries.
PubMed: Evaluation of the gastric antiulcerogenic effects of Solanum nigrum, Brassica oleracea and Ocimum basilicum in rats.
PubMed: Biosynthesis of estragole and methyl-eugenol in sweet basil (Ocimum basilicum L). Developmental and chemotypic association of allylphenol O-methyltransferase activities.
PubMed: The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil.
PubMed: Radioprotective effect of leaf extract of Indian medicinal plant Ocimum sanctum.
PubMed: Guard cell apoplastic photosynthate accumulation corresponds to a phloem-loading mechanism.
PubMed: Rapid staining method to detect and identify downy mildew (Peronospora belbahrii) in basil.
PubMed: Protection of cadmium chloride induced DNA damage by Lamiaceae plants.
PubMed: Interaction of Salmonella enterica with basil and other salad leaves.
PubMed: An investigation of the storage and biosynthesis of phenylpropenes in sweet basil.
PubMed: Characterization of geraniol synthase from the peltate glands of sweet basil.
PubMed: Antidiarrhoeal activities of Ocimum gratissimum (Lamiaceae).
PubMed: Antimelanoma and radioprotective activity of alcoholic aqueous extract of different species of Ocimum in C(57)BL mice.
PubMed: Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines.
PubMed: Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus.
PubMed: Phylogeny and evolution of basils and allies (Ocimeae, Labiatae) based on three plastid DNA regions.
PubMed: Enantiomeric composition of (3R)-(-)- and (3S)-(+)-linalool in various essential oils of Indian origin by enantioselective capillary gas chromatography-flame ionization and mass spectrometry detection methods.
PubMed: Folklore therapeutic indigenous plants in periodontal disorders in India (review, experimental and clinical approach).
PubMed: Activity of essential oils and individual components against acetyl- and butyrylcholinesterase.
PubMed: Study of ambient ozone phytotoxicity in Ukraine and ozone protective effect of some antioxidants.
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