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perilla leaf oil
essential oil obtained from the leaves of the plant, perilla frutescens, labiatae

Sponsors

Name:perilla frutescens leaf oil
CAS Number: 68132-21-8
Also Contains:perilla frutescens leaf extract
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
FEMA Number:4013 perilla leaf oil
FDA Mainterm: PERILLA LEAF OIL
 
Physical Properties:
Appearance:pale yellow to yellow clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity:0.90900 to 0.92900 @ 20.00 °C.
Pounds per Gallon - (est).: 7.573 to 7.739
 
Organoleptic Properties:
Odor Type: herbal
Odor Strength:medium
herbal green spicy caraway apple tea
Odor Description:at 100.00 %. herbal green spicy caraway apple tea
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Berjé
Perilla Oil
Happening at Berje
Liberty Natural Products
PERILLA OIL GREEN
Penta International
PERILLA LEAF OIL, Kosher
Robertet
Shiso Ess. oil (for fragrance)
Robertet
Shiso Essential Oil Asia
Odor: Shiso scent is green, caraway, apple pip, producing a sensation of freshness and naturalness in perfumes
Use: Hydrodistillation of Japanese Perilla Nankin leaves.
Soda Aromatic
Perilla Leaf Oil
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2770 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 397, 1988.

oral-rat LDLo 5000 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 397, 1988.

Dermal Toxicity:
skin-guinea pig LDLo 5000 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 397, 1988.

skin-rabbit LDLo 5000 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 397, 1988.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
perillaldehyde Max. Found: <60.00 % and Reason: Sensitization
Recommendation for perilla leaf oil usage levels up to:
  6.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 20
 average usual ppmaverage maximum ppm
baked goods: 10.00000100.00000
beverages(nonalcoholic): 2.00000200.00000
beverages(alcoholic): 1.0000010.00000
breakfast cereal: --
cheese: --
chewing gum: 20.000002000.00000
condiments / relishes: --
confectionery froastings: 1.0000020.00000
egg products: --
fats / oils: 1.0000010.00000
fish products: --
frozen dairy: 2.00000200.00000
fruit ices: 2.00000200.00000
gelatins / puddings: 2.00000200.00000
granulated sugar: --
gravies: --
hard candy: 2.00000200.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: 5.00000100.00000
reconstituted vegetables: --
seasonings / flavors: 100.00000500.00000
snack foods: 1.00000100.00000
soft candy: 2.00000200.00000
soups: 1.00000100.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):68132-21-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
perilla frutescens leaf oil
Chemidplus:0068132218
 
References:
 perilla frutescens leaf oil
Canada Domestic Sub. List:68132-21-8
Pubchem (sid):199105
 
Other Information:
FDA Everything Added to Food in the United States (EAFUS):View
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
 
Potential Blenders and core components note
For Odor
aldehydic
agrumen nitrile
FR
animal
iso
butyl quinoline
FR
anisic
estragole
FL/FR
ocimum basilicum herb oil
FL/FR
ocimum basilicum herb oil egypt
FL/FR
ocimum basilicum leaf oil america
FL/FR
ocimum basilicum leaf oil CO2 extract
FL/FR
ocimum basilicum leaf oil india
FL/FR
balsamic
(E)-
cinnamyl alcohol
FL/FR
cinnamyl formate
FL/FR
guaiyl acetate
FL/FR
2-
phenyl propyl alcohol
FL/FR
christmas
pine fragrance
FR
caramellic
2-iso
butyl-3-methyl pyrazine
FL/FR
citrus
bergamot oil
FL/FR
bergamot oil bergaptene reduced italy
FL/FR
bergamot oil turkey
FL/FR
iso
decyl acetate
FR
ocimene quintoxide
FL/FR
earthy
geosmin
FL/FR
(S)-1-
octen-3-ol
FL/FR
ethereal
ethyl 4-pentenoate
FL/FR
fatty
(R)-gamma-
octalactone
FL/FR
2-
octenal
FL/FR
floral
cassis oxime 10%
FR
cassis specialty
FR
cilantro herb oil egypt
FL/FR
cymbopogon validus leaf oil
FR
dictamnus hispanicus oil
FR
dihydrocitronellyl ethyl ether
FR
dihydrorose oxide
FR
dimethyl benzyl carbinyl butyrate
FL/FR
2,4-
dimethyl-3-cyclohexene-1-methanol
FR
geranium oil
FL/FR
geranium oil bourbon
FL/FR
geranium oil egypt
FL/FR
heliotropyl diethyl acetal
FR
jonquil absolute
FR
jonquil absolute replacer
FR
linden flower absolute
FR
melaleuca ericifolia leaf oil
FR
ortho-
methoxybenzyl ethyl ether
FR
1-(2-
methyl allyl oxy)-2-methyl butane
FR
para-
methyl benzyl acetate
FL/FR
neryl formate
FL/FR
3-
nonanone
FL/FR
phenyl propyl phenyl acetate
FR
iso
phytol
FL/FR
prenyl salicylate
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR
rose pyran
FR
5-
tricyclodecenyl acetate
FR
fruity
3-
butyl bicyclo[3.2.1]-6-octen-2-one
FR
cinnamyl hexanoate
FL/FR
ethyl 2-ethyl acetoacetate
FL/FR
tropical indene
FR
fungal
jasmin nonane
FR
green
agrumen aldehyde
FR
birch leaf specialty
FR
iso
butyl heptanoate
FL/FR
iso
butyl methyl ketone
FL/FR
S-sec-
butyl thioisovalerate
FL/FR
carrot leaf oil (daucus carota ssp.maximus)
FR
chrysanthemum carbaldehyde
FR
heptanal (aldehyde C-7)
FL/FR
heptyl benzoate
FL/FR
3-
hexenyl 2-methyl butyrate
FL/FR
hop oil CO2 extract
FL/FR
english
ivy leaf absolute
FR
marigold pot absolute
FL/FR
6-
methyl-3-hepten-2-one
FL/FR
murraya koenigii leaf oil india
FL/FR
3-
propyl bicyclo(3.2.1)-6-octen-2-one
FR
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
terpinyl propionate
FL/FR
triplal / ethyl anthranilate schiff's base
FR
herbal
anethum graveolens herb oil
FL/FR
anethum graveolens herb tincture
FL/FR
anthemis nobilis flower extract
FL/FR
anthemis nobilis flower oil roman
FL/FR
apium graveolens seed oil
FL/FR
apium graveolens seed oil india
FL/FR
artemisia alba oil
FR
sweet
basil absolute
FL/FR
(+)-alpha-
campholenic aldehyde
FL/FR
carrot seed oil (daucus carota ssp. gummifer hook. fil.) spain
FR
carrot seed oil (daucus carota ssp. maximus (desf.) ball)
FR
wild
carrot seed oil terpeneless
FL/FR
celery ketone
FL/FR
chrysanthemum ketone
FR
clary sage absolute
FL/FR
coriander oleoresin
FL/FR
daucus carota fruit oil
FL/FR
dill seed oil CO2 extract indian
FL/FR
dill seed oil indian
FL/FR
dill weed oil cuba
FL/FR
dill weed oil reunion
FL/FR
dimethyl benzyl carbinyl formate
FL/FR
2-(2,4-
dimethyl-3-cyclohexene-1-yl)-4,4-dimethyl-1,3-oxathiane
FR
cis-
herbal cyclohexane
FR
herbal dioxane
FR
herbal heptane
FR
hop absolute
FL/FR
hop oil
FL/FR
lantana camara flower oil
FR
marigold oil mexico
FL/FR
melaleuca leucadendron var. cajuputi leaf oil
FL/FR
1-(2-
methyl allyl oxy) heptane
FR
(E)-6-
methyl-3-hepten-2-one
FL/FR
monarda fistulosa oil
FR
nonisyl formate
FR
1-
octen-3-yl acetate
FL/FR
oregano specialty
FR
origanum oil
FL/FR
origanum oil greece
FL/FR
curled
parsley seed oil
FL/FR
perillaldehyde
FL/FR
petroselinum crispum seed oil CO2 extract
FL/FR
phenyl acetaldehyde diisoamyl acetal
FR
prenyl senecioate
FL/FR
reseda absolute
FR
rosmarinus officinalis extract
FL/FR
rosmarinus officinalis tincture
FL/FR
tagete oil CO2 extract
FL/FR
tagete oil rwanda
FL/FR
theaspirane
FL/FR
thyme absolute
FL/FR
tricyclodecyl acetate
FR
viridiflorol
FL/FR
wormwood oil america
FL/FR
wormwood oil italy
FL/FR
wormwood oil poland
FL/FR
licorice
ocimum basilicum herb oil vietnam
FL/FR
ocimum basilicum leaf oil terpeneless
FL/FR
minty
(-)-
menthone
FL/FR
mossy
treemoss absolute
FR
soapy
methyl anthranilate / hexyl cinnamaldehyde schiff's base
FR
spicy
iso
butyl angelate
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
cumin seed absolute
FL/FR
cuminaldehyde
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
iso
cyclogeraniol (IFF)
FR
2-
octanol
FL/FR
origanum majorana oil
FL/FR
outdoors specialty
FR
spicy carbonate
FR
annus
wormwood oil vietnam
FL/FR
sulfurous
lychee mercaptan acetate
FL/FR
woody
cinnamyl tiglate
FL/FR
dalbergia sissoo leaf oil
FR
alpha-
farnesene
FL/FR
alpha-
farnesene isomer
FL/FR
verdoxan
FR
For Flavor
No flavor group found for these
4-
acetyl-2-isopropenyl pyridine
FL
iso
butyl heptanoate
FL/FR
4-
butyl thiazole
FL
S-sec-
butyl thioisovalerate
FL/FR
(E)-
cinnamyl alcohol
FL/FR
cinnamyl hexanoate
FL/FR
cinnamyl tiglate
FL/FR
dimethyl benzyl carbinyl formate
FL/FR
ethyl 4-pentenoate
FL/FR
fig leaf absolute
FL
guaiyl acetate
FL/FR
heptyl benzoate
FL/FR
(E,E)-2,4-
hexadien-1-ol
FL
melaleuca leucadendron var. cajuputi leaf oil
FL/FR
(E)-6-
methyl-3-hepten-2-one
FL/FR
6-
methyl-3-hepten-2-one
FL/FR
(R)-gamma-
octalactone
FL/FR
(S)-1-
octen-3-ol
FL/FR
2-
octenal
FL/FR
3-
octyl butyrate
FL
prenyl senecioate
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
4,4'-
thiobis-2-butanone
FL
ortho-
vinyl anisole
FL
viridiflorol
FL/FR
anisic
anisic
ocimum basilicum herb oil egypt
FL/FR
citrus
bergamot oil
FL/FR
bergamot oil bergaptene reduced italy
FL/FR
bergamot oil turkey
FL/FR
cooling
theaspirane
FL/FR
earthy
geosmin
FL/FR
ethereal
4-
hexen-3-one
FL
floral
dimethyl benzyl carbinyl butyrate
FL/FR
geranium oil
FL/FR
geranium oil bourbon
FL/FR
geranium oil egypt
FL/FR
fruity
ethyl 2-ethyl acetoacetate
FL/FR
para-
methyl benzyl acetate
FL/FR
(E,E)-
methyl sorbate
FL
neryl formate
FL/FR
tagete oil CO2 extract
FL/FR
tagete oil rwanda
FL/FR
green
anethum graveolens herb tincture
FL/FR
iso
butyl angelate
FL/FR
iso
butyl methyl ketone
FL/FR
2-iso
butyl-3-methyl pyrazine
FL/FR
(+)-alpha-
campholenic aldehyde
FL/FR
celery distillates
FL
celery ketone
FL/FR
clary sage absolute
FL/FR
coriander oleoresin
FL/FR
alpha-
farnesene
FL/FR
alpha-
farnesene isomer
FL/FR
heptanal (aldehyde C-7)
FL/FR
3-
hexenyl 2-methyl butyrate
FL/FR
marigold pot absolute
FL/FR
3-
nonanone
FL/FR
ocimene quintoxide
FL/FR
1-
octen-3-yl acetate
FL/FR
2-
phenyl propyl alcohol
FL/FR
terpinyl propionate
FL/FR
herbal
anethum graveolens herb oil
FL/FR
anthemis nobilis flower extract
FL/FR
anthemis nobilis flower oil roman
FL/FR
apium graveolens seed oil
FL/FR
apium graveolens seed oil india
FL/FR
sweet
basil absolute
FL/FR
wild
carrot seed oil terpeneless
FL/FR
celery seed oleoresin
FL
cilantro herb oil egypt
FL/FR
daucus carota fruit oil
FL/FR
dill weed oil cuba
FL/FR
dill weed oil reunion
FL/FR
hop absolute
FL/FR
hop oil
FL/FR
marigold oil mexico
FL/FR
ocimum basilicum herb oil
FL/FR
ocimum basilicum leaf oil america
FL/FR
ocimum basilicum leaf oil CO2 extract
FL/FR
ocimum basilicum leaf oil india
FL/FR
origanum majorana oil
FL/FR
origanum oil
FL/FR
origanum oil greece
FL/FR
curled
parsley seed oil
FL/FR
petroselinum crispum seed oil CO2 extract
FL/FR
prenyl salicylate
FL/FR
rosmarinus officinalis extract
FL/FR
rosmarinus officinalis tincture
FL/FR
thyme absolute
FL/FR
wormwood oil america
FL/FR
wormwood oil italy
FL/FR
wormwood oil poland
FL/FR
juicy
lychee mercaptan acetate
FL/FR
licorice
estragole
FL/FR
ocimum basilicum herb oil vietnam
FL/FR
ocimum basilicum leaf oil terpeneless
FL/FR
minty
(-)-
menthone
FL/FR
oily
iso
phytol
FL/FR
spicy
cinnamaldehyde dimethyl acetal
FL/FR
cinnamyl formate
FL/FR
cumin seed absolute
FL/FR
cuminaldehyde
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
dill seed oil CO2 extract indian
FL/FR
dill seed oil indian
FL/FR
hop oil CO2 extract
FL/FR
murraya koenigii leaf oil india
FL/FR
2-
octanol
FL/FR
perillaldehyde
FL/FR
annus
wormwood oil vietnam
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 perilla
Search Trop Picture
 
Synonyms:
 essential oil obtained from the leaves of the plant, perilla frutescens, labiatae
 ocimum frutescens leaf oil
 perilla frutescens leaf oil
 perilla frutescens var. frutescens leaf oil
 perilla leaf oil
 perilla ocymoides leaf oil
 salvia infuscata leaf oil
 shiso ess. oil (for fragrance) (Robertet)
 shiso essential oil asia (Robertet)
 shiso leaf oil
 

Articles:

PubMed:Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
PubMed:Synthesis of gold and silver nanoparticles using leaf extract of Perilla frutescens--a biogenic approach.
PubMed:Rosmarinic acid extract for antioxidant, antiallergic, and α-glucosidase inhibitory activities, isolated by supramolecular technique and solvent extraction from Perilla leaves.
PubMed:Perilla frutescens leaf extract inhibits mite major allergen Der p 2-induced gene expression of pro-allergic and pro-inflammatory cytokines in human bronchial epithelial cell BEAS-2B.
PubMed:Accumulation of PrLeg, a Perilla legumin protein in potato tuber results in enhanced level of sulphur-containing amino acids.
PubMed:Essential oil of Perilla frutescens-induced change in hippocampal expression of brain-derived neurotrophic factor in chronic unpredictable mild stress in mice.
PubMed:Perilla frutescens (L.) Britton: honeybee forage and preliminary results on the metabolic profiling by NMR spectroscopy.
PubMed:Nuclear Factor-κB: central regulator in ocular surface inflammation and diseases.
PubMed:Optimization of antibacterial activity of Perilla frutescens var. acuta leaf against Staphylococcus aureus using evolutionary operation factorial design technique.
PubMed:Controllable spectrum artificial sunlight source system using LEDs with 32 different peak wavelengths of 385-910 nm.
PubMed:Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions.
PubMed:Optimization of antibacterial activity of Perilla frutescens var. acuta leaf against Pseudomonas aeruginosa using the evolutionary operation-factorial design technique.
PubMed:Monoterpene engineering in a woody plant Eucalyptus camaldulensis using a limonene synthase cDNA.
PubMed:Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf.
PubMed:Perilla leaf, Perilla frutescens, induces apoptosis and G1 phase arrest in human leukemia HL-60 cells through the combinations of death receptor-mediated, mitochondrial, and endoplasmic reticulum stress-induced pathways.
PubMed:Antioxidant activities of polyphenols extracted from Perilla frutescens varieties.
PubMed:Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System.
PubMed:Rosmarinic acid from Perillae Herba produces an antidepressant-like effect in mice through cell proliferation in the hippocampus.
PubMed:Perilla frutescens var. frutescens in northern Laos.
PubMed:Growth inhibitory and apoptosis inducing effect of Perilla frutescens extract on human hepatoma HepG2 cells.
PubMed:Protective effect of aqueous extract of Perilla frutescens on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in rats.
PubMed:Anthocyanin and flavonoid production from Perilla frutescens: pilot plant scale processing including cross-flow microfiltration and reverse osmosis.
PubMed:Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse model.
PubMed:Limonene production in tobacco with Perilla limonene synthase cDNA.
PubMed:Inhibitory effect of Perilla leaf extract and luteolin on mouse skin tumor promotion.
PubMed:Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens.
PubMed:[Inhibition of antigen-specific T helper type 2 responses by Perilla frutescens extract].
PubMed:The effects of developmental stage and source leaf position on integration and sectorial patterns of carbohydrate movement in an annual plant, Perilla frutescens (Lamiaceae).
PubMed:Genetic analysis of essential oil variants in Perilla frutescens.
PubMed:Genetic Control of Peltate Glandular Trichome Formation in Perilla frutescens.
PubMed:An Intestinal Propulsion Promoting Substance from Perilla frutescens and Its Mechanism of Action.
PubMed:Separation and measurement of direct and indirect effects of light on stomata.
 
Notes:
an oil rich in alpha-linolenic acid. tsca definition 2008: extractives and their physically modified derivatives. perilla frutescens, var. crispa, labiatae.
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