Articles:
| None found yet. Try the PubMed Search. |
Notes:
Blends well with balsamic notes. Clary sage and citrus oils makes a nice amber cologne. Adds a honey miel sweet note to otto of rose fragrances.
a pine weevil antifeedant. Occurs in storax. Also present in many fruits, e.g. cherry, American cranberry, pineapple, blackberry and passion fruit
| Fragrance Demo Formulas Flavor Demo Formulas | ||
| Name: | ethyl 3-phenylprop-2-enoate | |
| CAS Number: | 103-36-6 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 203-104-6 | |
| FDA UNII: | C023P3M5JJ | |
| Beilstein Number: | 0775541 | |
| MDL: | MFCD00009189 | |
| FEMA Number: | 2430 | |
| CoE Number: | 323 | |
| XlogP3: | 3.00 (est) | |
| Molecular Weight: | 176.21504000 | |
| Formula: | C11 H12 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| Also(can) Contains: | ethyl (E)-cinnamate | |
| ethyl (Z)-cinnamate | ||
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 659 ethyl cinnamate |
| Flavis Number: | 09.730 (Old) |
| DG SANTE Food Flavourings: | 09.730 ethyl cinnamate |
| FEMA Number: | 2430 ethyl cinnamate |
| FDA Mainterm: | ETHYL CINNAMATE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
Physical Properties:
| Appearance: | colorless clear oily liquid (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 1.04500 to 1.04800 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 8.695 to 8.720 |
| Refractive Index: | 1.55900 to 1.56100 @ 20.00 °C. |
| Melting Point: | 6.00 to 7.50 °C. @ 760.00 mm Hg |
| Boiling Point: | 271.00 to 272.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 158.00 to 159.00 °C. @ 24.00 mm Hg |
| Acid Value: | 1.00 max. KOH/g |
| Vapor Pressure: | 0.003270 mmHg @ 25.00 °C. |
| Vapor Density: | 6.0 ( Air = 1 ) |
| Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w): | 2.990 |
| Shelf Life: | 24.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| alcohol | |
| fixed oils | |
| water, 160.6 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| glycerin | |
| Stability: | |
| non-discoloring in most media | |
| Similar Items: note | |
| allyl cinnamate | |
| amyl cinnamate | |
| isoamyl cinnamate | |
| benzyl cinnamate | |
| butyl cinnamate | |
| isobutyl cinnamate | |
| cinnamyl cinnamate | |
| citronellyl cinnamate | |
| cyclohexyl cinnamate | |
| ethyl alpha-acetyl cinnamate | |
| heptyl cinnamate | |
| (Z)-3-hexen-1-yl cinnamate | |
| hexyl cinnamate | |
| linalyl cinnamate | |
| methyl cinnamate | |
| octyl cinnamate | |
| phenethyl cinnamate | |
| 3-phenyl propyl cinnamate | |
| propyl cinnamate | |
| isopropyl cinnamate | |
| terpinyl cinnamate | |
| tetrahydrofurfuryl cinnamate | |
Organoleptic Properties:
| Odor Type: | balsamic |
| Odor Strength: | medium |
| Odor Description: at 100.00 %. | sweet balsam fruity spicy powdery berry plum |
| Substantivity: | 400 Hour(s) |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
perfuming agents uv absorbers |
Safety Information:
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Human Experience: | 4 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 4000 mg/kg Voprosy Pitaniya. Problems of Nutrition. Vol. 33(5), Pg. 48, 1974. oral-guinea pig LD50 4000 mg/kg Voprosy Pitaniya. Problems of Nutrition. Vol. 33(5), Pg. 48, 1974. oral-rat LD50 4000 mg/kg Voprosy Pitaniya. Problems of Nutrition. Vol. 33(5), Pg. 48, 1974. | |
| Dermal Toxicity: | |
|
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 719, 1974. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| maximum skin levels for fine fragrances: | |||
| 0.1300 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2001) | |||
| Recommendation for ethyl cinnamate usage levels up to: | |||
| 8.0000 % in the fragrance concentrate. | |||
| use level in formulae for use in cosmetics: | |||
| 0.0130 % | |||
| Dermal Systemic Exposure in Cosmetic Products: | |||
| 0.0003 mg/kg/day (IFRA, 2001) | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 89.00 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 70.00 (μg/capita/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 12.00000 | |
| beverages(nonalcoholic): | - | 4.10000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | 11.00000 | 40.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 8.80000 | |
| fruit ices: | - | 8.80000 | |
| gelatins / puddings: | - | 2.40000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 9.50000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of cinnamyl derivatives used as flavor ingredients.View pdf | |
| European Food Safety Athority(efsa): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 15 (FGE.15): Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Flavouring Group Evaluation 55 (FGE.55): Consideration of phenyl-substituted aliphatic alcohols and related aldehydes and esters evaluated by JECFA (63rd meeting) structurally related to phenethyl alcohol, aldehyde, esters and related phenylacetic acid esters evaluated by EFSA in FGE.14 (2005) and aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives evaluated by EFSA in FGE.15 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 15, Revision 1 (FGE.15Rev1) - Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 68 (FGE.68): Consideration of cinnamyl alcohol and related flavouring agents evaluated by JECFA (55th meeting) evaluated by EFSA in FGE.15Rev1 (2008) View page or View pdf | |
| Safety and efficacy of aryl-substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species View page or View pdf | |
| EPI System: | View |
| Env. Mutagen Info. Center: | Search |
| EPA Substance Registry Services (TSCA): | 103-36-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 7649 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| ethyl 3-phenylprop-2-enoate | |
| Chemidplus: | 0000103366 |
| RTECS: | GD9010000 for cas# 103-36-6 |
References:
| ethyl 3-phenylprop-2-enoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 103-36-6 |
| Pubchem (cid): | 7649 |
| Pubchem (sid): | 134972070 |
| Flavornet: | 103-36-6 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2009 |
| (IUPAC): | Atomic Weights of the Elements 2009 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Everything Added to Food in the United States (EAFUS): | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C06359 |
| HMDB (The Human Metabolome Database): | HMDB33834 |
| FooDB: | FDB012002 |
| YMDB (Yeast Metabolome Database): | YMDB01689 |
| Export Tariff Code: | 2916.39.7900 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| RSC Learn Chemistry: | View |
Potential Blenders and core components note
Potential Uses:
| almond | FR | |
| amber | FR | |
| apricot | FR | |
| balsam | FR | |
| benzoinett | FR | |
| berry | FR | |
| cherry | FR | |
| cherry blossom | FR | |
| chypre | FR | |
| cinnamon | FR | |
| clary sage oil replacer | FR | |
| currant | FR | |
| fern | FR | |
| fixer | ||
| floral | FR | |
| grape | FR | |
| guava | FR | |
| honey | FR | |
| jasmin | FR | |
| lavender | FR | |
| lavender flower | FL/FR | |
| narcissus | FR | |
| nut | FL | |
| oriental | FR | |
| passion fruit | FR | |
| peach | FR | |
| pear | FR | |
| plum | FR | |
| powder | FR | |
| raspberry | FR | |
| rose | FR | |
| spice | FR | |
| strawberry | FR | |
| vanilla | FR | |
| woody | FR |
Occurrence (nature, food, other): note
| cactus prickly pear Search Trop Picture | |
| cassia plant Search Trop Picture | |
| champaca concrete @ trace% Data GC Search Trop Picture | |
| cinnamon ceylon cinnamon bark Search Trop Picture | |
| cinnamon ceylon cinnamon leaf oil Search Trop Picture | |
| cinnamon ceylon cinnamon root bark Search Trop Picture | |
| clove plant Search Trop Picture | |
| corn silk Search Trop Picture | |
| currant fruit Search Picture | |
| guava fruit Search Trop Picture | |
| passion fruit Search Trop Picture | |
| peach fruit Search Trop Picture | |
| plum fruit Search Trop Picture | |
| strawberry wild strawberry fruit Search Trop Picture | |
| tamarind fruit Search Trop Picture | |
| tamarind seed Search Trop Picture | |
| tarragon plant Search Trop Picture | |
| wine red wine Search Picture | |
| wine white wine Search Picture |
Synonyms:
| cinnamic acid ethyl ester | |
| ethyl 3-phenyl acrylate | |
| ethyl 3-phenyl propenoate | |
| ethyl 3-phenyl-2-propenoate | |
| ethyl 3-phenylacrylate | |
| ethyl 3-phenylprop-2-enoate | |
| ethyl benzylidene acetate | |
| ethyl beta-phenyl acrylate | |
| nat. | ethyl cinnamate |
| ethyl cinnamate (natural) | |
| ethyl cinnamate FCC | |
| ethyl cinnamate natural | |
| ethyl phenyl acrylate | |
| 3- | phenyl-2-propenoic acid ethyl ester |
| 3- | phenyl-2-propenoic acid, ethyl ester |
| 3- | phenyl-acrylic acid, ethyl ester |
| 2- | propenoic acid, 3-phenyl-, ethyl ester |