cinnamon bark oil (cinnamomum zeylanicum) india
volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
 
Notes:
Use with Caution and in only very small quantites. Will irritate skin. To reduce the irritating affects of the oil blend with Eugenol (Clove oil) 50/50. Steam distilled from the dried inner bark of Cinnamomum spp.. Europe and U.S.A. oils are the best. The color of this oily liquid is pale yellow to dark yellow. The odor is strong warm spicy sweet dry powdery dusty cinnamon. tsca definition 2008: extractives and their physically modified derivatives. cinnamomum zeylanicum, lauraceae.
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Name: cinnamomum verum bark oil
CAS Number: 8015-91-6 
CoE Number: 133
Also Contains: cinnamomum verum bark extract ceylon
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
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US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 2291  cinnamon bark oil (cinnamomum zeylanicum) india
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Appearance: dark yellow clear oily liquid (est)
Food Chemicals Codex Listed: No
Flash Point: 160.00 °F. TCC ( 71.11 °C. )
Soluble in:
 alcohol
 water, 2150 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 cream
 hair spray
 lipstick
 lotion
 powder
 soap
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Organoleptic Properties:
Odor Type: spicy
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 sweet  cinnamyl  spicy  warm  woody  aromatic  
Odor Description:
at 10.00 % in dipropylene glycol. 
sweet cinnamic spicy warm woody aromatic
 cinnamon  spicy  woody  warm  fruity  
Taste Description:
cinnamon spicy woody warm heat slightly fruity
Substantivity: 372 Hour(s)
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
perfuming agents
tonic
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Suppliers:
Artiste
Cinnamon Bark Oil
Ultra International
Cinnamon Oil
Crop Calendar
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Safety Information:
European information :
Most important hazard(s):
Xn - Harmful.
R 21 - Harmful in contact with skin.
R 36/38 - Irritating to skin and eyes.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37 - Wear suitable protective clothing and gloves.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  2650 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Sensitization
IFRA fragrance material specification:
 The prime allergen is Cinnamic aldehyde. The concentration of Cinnamic aldehyde in the finished cosmetic product should not exceed 0.1%.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
eugenol Max. Found: <6.00 % and Reason: Sensitization
benzaldehyde Max. Found: <0.20 % and Reason: Sensitization
benzyl benzoate Max. Found: <2.00 % and Reason: Sensitization
(E)-cinnamyl alcohol Max. Found: <8.90 % and Reason: Sensitization
(E)-cinnamaldehyde Max. Found: <90.00 % and Reason: Sensitization
Recommendation for cinnamon bark oil (cinnamomum zeylanicum) india usage levels up to:
  8.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -110.00000
beverages(nonalcoholic): -5.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -620.00000
condiments / relishes: -25.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -18.00000
fruit ices: -18.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -80.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -50.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 8015-91-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 cinnamomum verum bark oil
Chemidplus: 0008015916
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References:
 cinnamomum verum bark oil
Canada Domestic Sub. List: 8015-91-6
Pubchem (sid): 135346120
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.29.6000
 Typical G.C.
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: CINNAMOMUM OILS (INCLUDING CINNAMON AND CASSIA)
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Potential Blenders and core components note
 
For Odor
aldehydic
2-methyl undecanal (aldehyde C-12 mna)FL/FR
amber
 cistus ladaniferus resinoidFR
anisic
para-anisaldehydeFL/FR
ortho-anisaldehydeFL/FR
balsamic
isoamyl benzoateFL/FR
 amyris wood oilFL/FR
siam benzoin resinoidFL/FR
 benzyl cinnamateFL/FR
 benzyl salicylateFL/FR
 cinnamyl alcoholFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 opoponax absolute (balsamodendron kafal)FL/FR
3-phenyl propyl acetateFL/FR
 cycloteneFL/FR
chocolate
isoamyl phenyl acetateFL/FR
citrus
blood orange oil italyFL/FR
coconut
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
floral
 acetophenoneFL/FR
alpha-amyl cinnamaldehydeFL/FR
 benzyl acetateFL/FR
 bois de rose oil brazilFL/FR
 coriander seed oilFL/FR
 ethyl phenyl acetateFL/FR
 floral pyranolFR
 heliotropinFL/FR
 ocean propanalFL/FR
 orris rhizome absolute (iris pallida)FL/FR
 palmarosa oilFL/FR
 tetrahydrolinaloolFL/FR
fruity
 benzyl propionateFL/FR
gamma-decalactoneFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
herbal
 canarium luzonicum oilFL/FR
 carum carvi fruit oilFL/FR
 costmary oil (chrysanthemum balsamita)FR
 rosemary oil spainFL/FR
minty
 peppermint oil idahoFL/FR
mossy
 veramoss (IFF)FR
 canella bark oilFR
 cassia bark oil chinaFL/FR
 cassia bark oleoresinFL/FR
 cassia leaf oilFL/FR
 cinnamaldehydeFL/FR
 cinnamaldehyde / methyl anthranilate schiff's baseFR
 cinnamaldehyde ethylene glycol acetalFL/FR
 cinnamon acroleinFL/FR
 cinnamyl nitrileFR
 clove bud oilFL/FR
isoeugenyl acetateFL/FR
para-methoxycinnamaldehydeFL/FR
ortho-methoxycinnamaldehydeFL/FR
para-methyl cinnamaldehydeFL/FR
alpha-methyl cinnamaldehydeFL/FR
 methyl heptadienoneFL/FR
 myrtenalFL/FR
terpenic
 juniperus communis fruit oilFL/FR
tonka
 tonka bean absoluteFR
vanilla
 ethyl vanillinFL/FR
 vanillinFL/FR
woody
 guaiacwood oilFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 santallFR
 woody acetateFR
 
For Flavor
 
No flavor group found for these
2-furfurylidene butyraldehydeFL
para-methyl cinnamaldehydeFL/FR
anisic
ortho-anisaldehydeFL/FR
balsamic
siam benzoin resinoidFL/FR
 benzyl salicylateFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 opoponax absolute (balsamodendron kafal)FL/FR
3-phenyl propyl acetateFL/FR
caramellic
 caramel furanoneFL
 cycloteneFL/FR
cherry
para-methoxycinnamaldehydeFL/FR
citrus
blood orange oil italyFL/FR
corn chip
2-acetyl-2-thiazolineFL
creamy
para-anisaldehydeFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
floral
isoamyl phenyl acetateFL/FR
 bois de rose oil brazilFL/FR
 ocean propanalFL/FR
 palmarosa oilFL/FR
 tetrahydrolinaloolFL/FR
fruity
isoamyl benzoateFL/FR
 benzyl acetateFL/FR
 benzyl propionateFL/FR
gamma-decalactoneFL/FR
 heliotropinFL/FR
green
 canarium luzonicum oilFL/FR
 cinnamyl alcoholFL/FR
 methyl heptadienoneFL/FR
herbal
 carum carvi fruit oilFL/FR
 coriander seed oilFL/FR
 rosemary oil spainFL/FR
honey
 ethyl phenyl acetateFL/FR
minty
 myrtenalFL/FR
 peppermint oil idahoFL/FR
powdery
 acetophenoneFL/FR
spicy
 benzyl cinnamateFL/FR
 benzylidene acetoneFL
 cassia bark oil chinaFL/FR
 cassia bark oleoresinFL/FR
 cassia leaf oilFL/FR
 cinnamaldehydeFL/FR
 cinnamaldehyde ethylene glycol acetalFL/FR
 cinnamon acroleinFL/FR
 clove bud oilFL/FR
isoeugenyl acetateFL/FR
ortho-methoxycinnamaldehydeFL/FR
alpha-methyl cinnamaldehydeFL/FR
sweet
 orris rhizome absolute (iris pallida)FL/FR
terpenic
 juniperus communis fruit oilFL/FR
tropical
alpha-amyl cinnamaldehydeFL/FR
vanilla
 ethyl vanillinFL/FR
 vanillinFL/FR
waxy
2-methyl undecanal (aldehyde C-12 mna)FL/FR
woody
 amyris wood oilFL/FR
 guaiacwood oilFL/FR
 patchouli oilFL/FR
 
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Potential Uses:
 allspiceFR
 almondFR
 alpine bouquet 
 amberFR
 appleFR
 balsamFR
 bayberryFR
 benzoin 
 blue dream 
 bouquetFR
 carnation dianthus oeilletFR
 cassiaFR
 cherry blossomFR
 chypreFR
 cinnamonFR
 forest pine forestFR
 fruitFR
 gingerbreadFR
 grass sweetFR
 herbalFR
 huile de mille fleurs 
 jockey club 
 lycheeFR
 mimosaFR
 muskFR
 orientalFR
 orris irisFR
 patchouliFR
 pina coladaFR
 pineFR
 powderFR
 pumpkin pieFR
 roseFR
 rose dog roseFR
 sandalwoodFR
 shalimar 
 spiceFR
 vanillaFR
 verbenaFR
 vetiverFR
 wallflowerFR
 windsor soap 
 woodyFR
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Occurrence (nature, food, other): note
 cinnamon ceylon cinnamon
Search Trop  Picture
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Synonyms:
 cinnamomum verum bark oil india
 cinnamomum zeylanicum bark oil india
 cinnamon bark oil (cinnamomum zeylanicum) india
 volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
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Articles:
PubMed: Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
PubMed: Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep 3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
PubMed: Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo.
PubMed: Invitro Anti-mycotic Activity of Hydro Alcoholic Extracts of Some Indian Medicinal Plants against Fluconazole Resistant Candida albicans.
PubMed: Anthelmintic activity of trans-cinnamaldehyde and A- and B-type proanthocyanidins derived from cinnamon (Cinnamomum verum).
PubMed: Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria.
PubMed: Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.
PubMed: Authentication of true cinnamon (Cinnamon verum) utilising direct analysis in real time (DART)-QToF-MS.
PubMed: Antibacterial Mode of Action of Cinnamomum verum Bark Essential Oil, Alone and in Combination with Piperacillin, Against a Multi-Drug-Resistant Escherichia coli Strain.
PubMed: Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria.
PubMed: Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States.
PubMed: Assessment of coumarin levels in ground cinnamon available in the Czech retail market.
PubMed: Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro.
PubMed: Functional and ultrastructural changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Cinnamomum verum essential oil.
PubMed: Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics.
PubMed: From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark.
PubMed: Does the taste matter? Taste and medicinal perceptions associated with five selected herbal drugs among three ethnic groups in West Yorkshire, Northern England.
PubMed: Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat.
PubMed: Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume.
PubMed: Anti-oxidant effects of cinnamon (Cinnamomum verum) bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat diet.
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