sucralose
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(2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol (Click)
CAS Number: 56038-13-2
ECHA EC Number: 259-952-2
FDA UNII: 96K6UQ3ZD4
Beilstein Number: 3654410
MDL: MFCD03648615
XlogP3: -1.50 (est)
Molecular Weight: 397.63303000
Formula: C12 H19 Cl3 O8
BioActivity Summary: listing
NMR Predictor: Predict
Category: sweeteners, flavor enhancers
 
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JECFA Food Additive: Sucralose
GSFA Codex: Sucralose (Trichlorogalactosucrose) (955).
FDA Mainterm: SUCRALOSE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.831 Sucralose.
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 130.00 °C. @ 760.00 mm Hg
Boiling Point: 669.43 °C. @ 760.00 mm Hg (est)
Flash Point: 678.00 °F. TCC ( 358.70 °C. ) (est)
logP (o/w): 0.229 (est)
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Organoleptic Properties:
Taste Description:
sweet
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
Aceto
Sucralose FCC
Anhui Haibei
Sucralose
Atlantic Chemicals
Sucralose
Carbosynth
Sucralose
For experimental / research use only.
CellMark AB
Sucralose
Flavorchem
Sucralose
Foodchem International
Compound Sweetener
Foodchem International
Sucralose
Graham Chemical
Sucralose
Kraft Chemical
Sucralose
Prinova
Sucralose FCC
Qingdao Dacon Trading
Sucralose
Tate & Lyle
SPLENDA® Sucralose
The Ingredient House
RightSweet™ Sucralose
Flavor: Intense sweet taste - approx. 600 times sweeter than sucrose
Viachem
Sucralose – Powder and Liquid
Flavor: sweet
Sucralose, C12H19Cl3O8, is a zero-calorie high-intensity, non-nutritive sweetener. Sucralose is approximately 600 times as sweet as sucrose (table sugar), twice as sweet as saccharin, and 3.3 times as sweet as aspartame. It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a longer shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste, stability, and safety. Sucralose is typically added to foods in very small quantities. It can be found in more than 4,500 food and beverage products and is used because it is a no-calorie sweetener, does not promote dental cavities, and is safe for consumption by diabetics. Sucralose is used as a replacement for, or in combination with, other artificial or natural sweeteners such as aspartame, acesulfame potassium (Ace-K) or high-fructose corn syrup. Sucralose is used in products such as candy, breakfast bars and soft drinks. It is also used in canned fruits wherein water and sucralose take the place of much higher calorie corn syrup based additives.
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
  Not determined
Dermal Toxicity:
  Not determined
Inhalation Toxicity:
  Not determined
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Safety in Use Information:
Category: sweeteners, flavor enhancers
Recommendation for sucralose usage levels up to:
 not for fragrance use.
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Safety References:
EPI System: View
Chemicalize.org: Calculate predicted properties
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
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Carcinogenic Potency Database: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA ACToR: Toxicology Data
National Institute of Allergy and Infectious Diseases: Data
 (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
Chemidplus: 0056038132
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References:
 (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 71485
Pubchem (sid): 135029485
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
aqueous solutions
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Natural Occurrence in: note
 not found in nature
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Synonyms:
(2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
 splenda
4,1',6'-trichloro-4,1',6'-trideoxy-galacto-sucrose
 trichlorogalactosucrose
 trichlorosucrose
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click on the picture(s) below to
interact with the 3D model
Picture of molecule
Soluble in:
 water, 2.275e+004 mg/L @ 25 °C (est)
 alcohol
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