methyl salicylate
 
Notes:
Blend with the benzoates to remove the harshness. used in over-the-counter liniments, ointments, lotions for relief of musculoskeletal aches and pains; has hemolytic effect on human & sheep erythrocytes. Present in white wine, tea, porcini mushroom Boletus edulis, Bourbon vanilla, clary sage, red sage and fruits incl. cherry, apple, raspberry, papaya and plum. Found in leaves of Gaultheria procumbens (wintergreen). Flavouring agent
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas    Flavor Demo Formulas
methyl 2-hydroxybenzoate (Click)
CAS Number: 119-36-8Picture of molecule
Other: 648434-07-5
ECHA EINECS - REACH Pre-Reg: 204-317-7
FDA UNII:LAV5U5022Y
Nikkaji Web: J2.915G
Beilstein Number: 0971516
MDL: MFCD00002214
FEMA Number: 2745
CoE Number: 433
XlogP3: 2.30 (est)
Molecular Weight: 152.14936000
Formula: C8 H8 O3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: ADI: 0-0.5 (JECFA, 1968).
Category: cosmetic, flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
JECFA Food Flavoring: 899  methyl salicylate
Flavis Number: 09.749 (Old)
DG SANTE Food Flavourings: 09.749  methyl salicylate
DG SANTE Food Contact Materials: methyl salicylate
FEMA Number: 2745  methyl salicylate
FDA Mainterm: METHYL SALICYLATE
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1010 Acrylic and modified acrylic plastics, semirigid and rigid.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to pink clear liquid (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.18000 to 1.18500 @  25.00 °C.
Pounds per Gallon - (est).: 9.819 to  9.860
Refractive Index: 1.53500 to 1.53800 @  20.00 °C.
Melting Point: -8.00 to  -7.00 °C. @ 760.00 mm Hg
Boiling Point: 222.00 to  224.00 °C. @ 760.00 mm Hg
Boiling Point: 132.00 to  133.00 °C. @ 50.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 0.034300 mm/Hg @ 25.00 °C.
Vapor Density: 5.26 ( Air = 1 )
Flash Point: 205.00 °F. TCC ( 96.00 °C. )
logP (o/w): 2.550
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 dipropylene glycol
 kerosene
 paraffin oil
 water, 700 mg/L @ 30 °C (exp)
Insoluble in:
 water
Stability:
 non-discoloring in most media
Similar Items: note
allyl salicylate
amyl salicylate
isoamyl salicylate
benzyl salicylate
bornyl salicylate
butyl salicylate
isobutyl salicylate
cinnamyl salicylate
ortho-cresyl salicylate
para-cresyl salicylate
cyclohexyl salicylate
decyl salicylate
2-ethyl hexyl salicylate
ethyl salicylate
heptyl salicylate
(Z)-3-hexen-1-yl salicylate
hexyl salicylate
menthyl salicylate
homomenthyl salicylate
2-methyl butyl salicylate
octyl salicylate
phenethyl salicylate
3-phenyl propyl salicylate
phenyl salicylate
prenyl salicylate
propyl salicylate
isopropyl salicylate
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: minty
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
Odor Description:
at 10.00 % in dipropylene glycol. 
wintergreen mint
Substantivity: 8 Hour(s)
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: denaturants
masking agents
perfuming agents
soothing agents
Synonyms   Articles   Notes   Search   Top
Safety Information:
Most important hazard(s):
Xn - Harmful.
  R 22 - Harmful if swallowed.
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
Human Experience: 8 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
  gavage-mouse LD50  [sex: M] 1390 mg/kg
(Ohsumi et al., 1984)

gavage-rat LD50  1250 mg/kg
(Giroux et al., 1954b)

oral-rat LD50  [sex: M,F] M:3049.00 F:2642 mg/kg
(Givaudan Corporation, 1982)

gavage-rat LD50  [sex: M,F] 887 mg/kg
(Jenner et al., 1964)

oral-rat LD50  1220 mg/kg
(Nivikov et al., 1994)

oral-mouse LD50  [sex: M] 1110 mg/kg
(Davison et al., 1961)

gavage-guinea pig LD50  [sex: M,F] 1060 mg/kg
(Jenner et al., 1964)

gavage-mouse LD50  [sex: M,F] 1440 mg/kg
(NTP, 1984a)

oral-woman LDLo  355 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: COMA
American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.

oral-rat LD50  887 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

oral-rabbit LD50  1300 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.

oral-mouse LD50  1110 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 207, 1961.

unreported-man LDLo  522 mg/kg
"Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.

oral-man LDLo  1329 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA BLOOD: HEMORRHAGE
Clinical Toxicology. Vol. 6, Pg. 189, 1973.

oral-man LDLo  101 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.

oral-human LDLo  506 mg/kg
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 961, 1989.

oral-guinea pig LD50  700 mg/kg
"Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1897, 1963.

oral-dog LD50  2100 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.

oral-child LDLo  700 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

oral-child LDLo  228 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Journal of Diseases of Children. Vol. 69, Pg. 37, 1945.

Dermal Toxicity:
  subcutaneous-dog LDLo 2250 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.

subcutaneous-guinea pig LDLo 1500 mg/kg
FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 63, 1967.

subcutaneous-rabbit LDLo 4250 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.

Inhalation Toxicity:
  Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: cosmetic, flavor and fragrance agents
maximum skin levels for fine fragrances:
  0.2900 %  and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2002)
Recommendation for methyl salicylate usage levels up to:
  10.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics:
  0.1300 %
Dermal Systemic Exposure in Cosmetic Products:
 0.0034 mg/kg/day (IFRA, 2002)
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 410.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 44000.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -54.00000
beverages(nonalcoholic): -59.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -8400.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -27.00000
fruit ices: -27.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -840.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009)
View page or View pdf
Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 119-36-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 4133
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 3082
WGK Germany:1
 methyl 2-hydroxybenzoate
Chemidplus: 0000119368
EPA/NOAA CAMEO:hazardous materials
RTECS: 119-36-8
Synonyms   Articles   Notes   Search   Top
References:
 methyl 2-hydroxybenzoate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 119-36-8
Pubchem (cid): 4133
Pubchem (sid): 134974376
Flavornet: 119-36-8
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C12305
HMDB (The Human Metabolome Database): HMDB34172
FooDB: FDB012459
YMDB (Yeast Metabolome Database): YMDB01370
Export Tariff Code: 2918.23.0000
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VCF-Online: VCF Volatile Compounds in Food
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RSC Learn Chemistry: View
Formulations/Preparations:
•usp: liniment, compound: menthol 4.5 g, camphor oil rectified 25 ml, olive or peanut oil 30 ml, methyl salicylate to make 100 ml. ointment, compound: methyl salicylate 10 ml, menthol 10 g, white wax 5 g, hydrous wool fat to make 100 g. •usp: spirit, phenolated (podiatry): liquefied phenol 1 ml, methyl salicylate 3 ml, compound myrcia spirit 25 ml, alcohol rubbing compound to make 100 ml. •grades: technical; usp; fcc.
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 mentha longifolia oil 
 camel grass oilFR
 cyclopentanoneFL/FR
 eucarvone 
 lippia alnifolia schau. leaf oil brazil 
laevo-monomenthyl glutarateFL/FR
laevo-menthyl methyl etherFL/FR
 pinocarvoneFL/FR
 satureja viminea oil costa rica 
 umbellulone 
aldehydic
 dodecanal (aldehyde C-12 lauric)FL/FR
animal
para-cresyl phenyl acetateFL/FR
anisic
para-anisaldehydeFL/FR
 dihydroanetholFL/FR
 estragoleFL/FR
balsamic
isoamyl benzoateFL/FR
 benzyl salicylateFL/FR
isobornyl acetateFL/FR
laevo-bornyl acetateFL/FR
isobornyl formateFL/FR
 cinnamyl alcoholFL/FR
 guaiacyl phenyl acetateFL/FR
 methyl cinnamateFL/FR
 nonyl benzoate 
 opoponax absolute (balsamodendron kafal)FL/FR
3-phenyl propyl alcoholFL/FR
camphoreous
dextro-camphorFL/FR
 camphor tree bark oilFL/FR
 herbal ethanoneFR
 thujyl alcoholFL/FR
caramellic
 ethyl maltolFL/FR
citrus
 ocimene quintoxideFL/FR
sweet orange peel oil c.p. brazilFL/FR
earthy
3-octanolFL/FR
 patchouli cyclohexanolFR
fatty
 decanolFL/FR
floral
alpha-amyl cinnamaldehydeFL/FR
isoamyl salicylateFL/FR
 amyl salicylateFL/FR
 benzyl acetateFL/FR
 bois de rose oil brazilFL/FR
isobutyl salicylateFL/FR
 citronellal diisotridecyl acetalFR
 coriander seed oilFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl acetateFL/FR
 cyclohexyl propanolFR
2-decalinolFR
 dihydrocarvyl acetateFL/FR
2',4'-dimethyl acetophenoneFL/FR
 earthy indaneFR
 floral methanolFR
 geraniolFL/FR
 geranium oil chinaFL/FR
 heliotropinFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 ho leaf oilFR
 hydroxycitronellalFL/FR
laevo-linaloolFL/FR
 linaloolFL/FR
 linalool oxideFL/FR
 menthadienyl formateFR
 muguet butanolFR
 ocean propanalFL/FR
 phenethyl acetateFL/FR
 phenethyl salicylateFL/FR
 rose butanoateFL/FR
 tetrahydrolinaloolFL/FR
 ylang ylang flower oil IIIFL/FR
fruity
 benzyl propionateFL/FR
3-benzyl-4-heptanoneFL/FR
2-cyclopentyl cyclopentanoneFL/FR
gamma-decalactoneFL/FR
 diethyl malonateFL/FR
 ethyl heptanoateFL/FR
 green acetateFR
 lilac lactoneFL/FR
 raspberry ketone methyl etherFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
green
 geranium absoluteFL/FR
(Z)-3-hexen-1-yl acetateFL/FR
(Z)-leaf acetalFL/FR
 thiogeraniolFL/FR
 artemisyl ketoneFL/FR
 barosma betulina leaf oilFL/FR
 carum carvi fruit oilFL/FR
1,4-cineoleFL/FR
 costmary oil (chrysanthemum balsamita)FR
2-cyclohexyl cyclohexanoneFR
 dehydroxylinalool oxideFL/FR
isodihydrolavandulolFR
(Z)-isodihydrolavandulyl acetateFR
2,10-epoxypinaneFR
 herbal undecanolFR
 hyssop oilFL/FR
 linalyl acetateFL/FR
para-menthane-3,8-diolFL/FR
 myrtenolFL/FR
 nopyl acetateFR
3-octyl acetateFL/FR
laevo-perillaldehydeFL/FR
 perillaldehydeFL/FR
 pine hexanolFR
D-(+)-alpha-pineneFL/FR
 piperitoneFL/FR
 rosemary absoluteFL/FR
 rosemary oil moroccoFL/FR
 sabinene hydrateFL/FR
common tansy flower oilFR
common tansy flower oil dutchFR
 viridiflorolFL/FR
licorice
sweet basil oleoresinFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil indiaFL/FR
 cornmint oil terpenelessFL/FR
(±)-mentholFL/FR
dextro,laevo-mentholFL/FR
dextro-neomentholFL/FR
laevo-mentholFL/FR
(±)-isomenthoneFL/FR
laevo-menthyl acetateFL/FR
 menthyl acetateFL/FR
 menthyl acetate racemicFL/FR
 peppermint cyclohexanoneFL/FR
dextro-piperitoneFL/FR
isopulegyl acetateFL/FR
minty
 agathosma crenulata oilFL/FR
 betula lenta bark oil americaFL/FR
 camphene hydrate 
laevo-carveolFL/FR
laevo-carvoneFL/FR
 carvoneFL/FR
cis-carvone-5,6-oxideFL/FR
 carvyl propionateFL/FR
beta-cyclocitralFL/FR
 cyclohexanoneFR
 dihydrocarveolFL/FR
 diosphenolFL/FR
 ethyl benzoateFL/FR
 ethyl salicylateFL/FR
bitter fennel seed oilFR
 gaultheria procumbens leaf extractFL/FR
dextro-2,8-para-menthadien-1-olFL/FR
trans-para-2,8-1-menthadienolFL/FR
trans-para-menthan-2-oneFL/FR
homomentholFL/FR
(-)-menthoneFL/FR
 menthoxypropane diolFL/FR
homomenthyl acetateFL/FR
2-methyl cyclohexanoneFL/FR
 pennyroyal oilFL/FR
 pennyroyal oil cubaFL/FR
 pennyroyal oil spainFL/FR
 pennyroyal oil uruguayFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil idahoFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil russiaFL/FR
 peppermint oil terpenelessFL/FR
beta-phellandreneFL/FR
 piperitenoneFL/FR
laevo-piperitoneFL/FR
isopropyl tiglateFL/FR
(-)-isopulegolFL/FR
(R)-(+)-pulegoneFL/FR
isopulegoneFL/FR
isopulegyl formateFL/FR
 spearmint absoluteFL/FR
 spearmint oil americaFL/FR
 spearmint oil terpenelessFL/FR
 tetrahydrocarvoneFL/FR
 vanillin menthoxypropane diol acetalFL/FR
 wintergreen oilFL/FR
 WS-23FL/FR
naphthyl
ortho-methyl anisoleFL/FR
pine
 plectranthus glandulosus hook f. leaf oil cameroon 
smoky
2,6-dimethoxyphenolFL/FR
spicy
 benzyl isoeugenolFL/FR
isobutyraldehydeFL/FR
 carvacrolFL/FR
 cassia bark oil chinaFL/FR
 cinnamon bark oil ceylonFL/FR
 clove bud oilFL/FR
 clove bud oleoresinFL/FR
N,N-diethyl octanamideFR
 eugenolFL/FR
alpha-methyl cinnamaldehydeFL/FR
 pimenta acris leaf oilFL/FR
laevo-verbenoneFL/FR
sulfurous
 buchu mercaptanFL/FR
 grapefruit menthaneFL/FR
sweet
 vanilla bean absolute (vanilla planifolia)FL/FR
terpenic
alpha-terpineolFL/FR
thujonic
 armoise oilFR
common tansy oil canadaFR
tonka
 coumarinFR
vanilla
 ethyl vanillinFL/FR
 vanillyl acetateFL/FR
waxy
1-dodecanolFL/FR
woody
para-tert-butyl cyclohexanoneFR
 gurjun balsam oilFR
 patchouli ethanolFR
 patchouli ethanoneFR
 patchouli hexanolFR
cis-2-pinanolFR
 santallFR
(Z)-woody amyleneFR
 
For Flavor
 
No flavor group found for these
 artemisyl ketoneFL/FR
laevo-bornyl acetateFL/FR
isobutyraldehydeFL/FR
 camphene hydrate 
laevo-carveolFL/FR
 carvoneFL/FR
cis-carvone-5,6-oxideFL/FR
 carvyl propionateFL/FR
beta-cyclocitralFL/FR
 cyclohexyl ethyl acetateFL/FR
 cyclopentanoneFL/FR
2-cyclopentyl cyclopentanoneFL/FR
2',4'-dimethyl acetophenoneFL/FR
(±)-N,N-dimethyl menthyl succinamideFL
 diosphenolFL/FR
 eucarvone 
 lilac lactoneFL/FR
 limonen-10-yl acetateFL
 lippia alnifolia schau. leaf oil brazil 
 mentha longifolia oil 
dextro-2,8-para-menthadien-1-olFL/FR
cis+trans-para-1(7)8-menthadien-2-yl acetateFL
trans-para-2,8-1-menthadienolFL/FR
para-menthane-3,8-diolFL/FR
homomentholFL/FR
3-laevo-menthoxy-2-methyl propane-1,2-diolFL
 menthoxypropane diolFL/FR
 menthyl acetate racemicFL/FR
laevo-monomenthyl glutarateFL/FR
laevo-menthyl methyl etherFL/FR
 menthyl propylene glycol carbonateFL
2-methyl cyclohexanoneFL/FR
 nonyl benzoate 
beta-phellandreneFL/FR
 phenethyl salicylateFL/FR
(Z,Z)-photocitral AFL
D-(+)-alpha-pineneFL/FR
 pinocarvoneFL/FR
 piperitenoneFL/FR
 piperitenone oxideFL
laevo-piperitoneFL/FR
dextro-piperitoneFL/FR
 piperitoneFL/FR
 plectranthus glandulosus hook f. leaf oil cameroon 
(-)-isopulegolFL/FR
isopulegoneFL/FR
isopulegyl formateFL/FR
 satureja viminea oil costa rica 
 umbellulone 
 vanillin menthoxypropane diol acetalFL/FR
laevo-verbenoneFL/FR
 viridiflorolFL/FR
 menthyl methyl lactateFL
 thujyl alcoholFL/FR
aldehydic
 decanolFL/FR
alliaceous
 benzyl mercaptanFL
aromatic
 amyl salicylateFL/FR
 benzyl isoeugenolFL/FR
para-cresyl phenyl acetateFL/FR
laevo-perillaldehydeFL/FR
balsamic
 benzyl salicylateFL/FR
 opoponax absolute (balsamodendron kafal)FL/FR
berry
 raspberry ketone methyl etherFL/FR
camphoreous
 camphor tree bark oilFL/FR
ortho-methyl anisoleFL/FR
caramellic
 ethyl maltolFL/FR
cherry
 heliotropinFL/FR
citrus
laevo-linaloolFL/FR
 linaloolFL/FR
sweet orange peel oil c.p. brazilFL/FR
alpha-terpineolFL/FR
coffee
2-isopropyl pyrazineFL
cooling
isobutyl salicylateFL/FR
1,4-cineoleFL/FR
laevo-mentholFL/FR
dextro,laevo-mentholFL/FR
homomenthyl acetateFL/FR
 menthyl acetateFL/FR
 sabinene hydrateFL/FR
 WS-5FL
creamy
para-anisaldehydeFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
floral
 bois de rose oil brazilFL/FR
 dihydrocarvyl acetateFL/FR
 geraniolFL/FR
 geranium oil chinaFL/FR
 linalyl acetateFL/FR
 ocean propanalFL/FR
 tetrahydrolinaloolFL/FR
 ylang ylang flower oil IIIFL/FR
fruity
isoamyl benzoateFL/FR
 benzyl acetateFL/FR
 benzyl propionateFL/FR
3-benzyl-4-heptanoneFL/FR
gamma-decalactoneFL/FR
 diethyl malonateFL/FR
 ethyl heptanoateFL/FR
 rose butanoateFL/FR
green
isoamyl salicylateFL/FR
 cinnamyl alcoholFL/FR
 cyclamen aldehydeFL/FR
 dihydrocarveolFL/FR
 geranium absoluteFL/FR
(Z)-3-hexen-1-yl acetateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
(Z)-leaf acetalFL/FR
 linalool oxideFL/FR
 ocimene quintoxideFL/FR
3-octyl acetateFL/FR
isopropyl tiglateFL/FR
herbal
2-acetoxy-1,8-cineoleFL
 barosma betulina leaf oilFL/FR
 carum carvi fruit oilFL/FR
 coriander seed oilFL/FR
 dihydroanetholFL/FR
 hyssop oilFL/FR
 rosemary absoluteFL/FR
 rosemary oil moroccoFL/FR
honey
 phenethyl acetateFL/FR
licorice
sweet basil oleoresinFL/FR
 estragoleFL/FR
meaty
2-methyl 3-(methyl thio) furanFL
medicinal
dextro-camphorFL/FR
2,6-dimethoxyphenolFL/FR
 ethyl benzoateFL/FR
mentholic
 cornmint oilFL/FR
 cornmint oil terpenelessFL/FR
(±)-mentholFL/FR
dextro-neomentholFL/FR
 peppermint cyclohexanoneFL/FR
minty
 agathosma crenulata oilFL/FR
 betula lenta bark oil americaFL/FR
laevo-carvoneFL/FR
 cornmint oil indiaFL/FR
 ethyl salicylateFL/FR
 gaultheria procumbens leaf extractFL/FR
trans-para-menthan-2-oneFL/FR
(-)-menthoneFL/FR
(±)-isomenthoneFL/FR
laevo-menthyl acetateFL/FR
 myrtenolFL/FR
 pennyroyal oilFL/FR
 pennyroyal oil cubaFL/FR
 pennyroyal oil spainFL/FR
 pennyroyal oil uruguayFL/FR
 peppermint oil CO2 extractFL/FR
 peppermint oil idahoFL/FR
 peppermint oil mongoliaFL/FR
 peppermint oil russiaFL/FR
 peppermint oil terpenelessFL/FR
(R)-(+)-pulegoneFL/FR
 spearmint absoluteFL/FR
 spearmint oil americaFL/FR
 spearmint oil terpenelessFL/FR
 teaberry flavorFL
 tetrahydrocarvoneFL/FR
 thiogeraniolFL/FR
 wintergreen flavorFL
 wintergreen oilFL/FR
 WS-23FL/FR
musty
3-octanolFL/FR
phenolic
 guaiacyl phenyl acetateFL/FR
soapy
 dodecanal (aldehyde C-12 lauric)FL/FR
1-dodecanolFL/FR
spicy
 carvacrolFL/FR
 cassia bark oil chinaFL/FR
 cinnamon bark oil ceylonFL/FR
 clove bud oilFL/FR
 clove bud oleoresinFL/FR
 eugenolFL/FR
4-methyl biphenylFL
alpha-methyl cinnamaldehydeFL/FR
 methyl cinnamateFL/FR
 perillaldehydeFL/FR
3-phenyl propyl alcoholFL/FR
 pimenta acris leaf oilFL/FR
sulfurous
 buchu mercaptanFL/FR
 grapefruit menthaneFL/FR
sweet
 vanilla bean absolute (vanilla planifolia)FL/FR
tropical
alpha-amyl cinnamaldehydeFL/FR
vanilla
 ethyl vanillinFL/FR
 vanillyl acetateFL/FR
waxy
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
woody
isobornyl acetateFL/FR
isobornyl formateFL/FR
 dehydroxylinalool oxideFL/FR
isopulegyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 acacia cassie farnesianaFR
 alpine bouquet 
 appleFR
 apricotFR
 birch beerFL
 blackberryFR
 blueberryFR
 boxwoodberry 
 bubble gumFR
 carnation dianthus oeilletFR
 cassiaFR
 cassia blossom 
 cassis black currant budFL/FR
 castoreumFR
 cherryFR
 chypreFR
 cloveFR
 cornmintFL/FR
 crabapple blossomFR
 cranberryFR
 currantFR
 dateFR
 fern fougereFR
 gardeniaFR
 gooseberryFR
 grapeFR
 grenadineFL
 hay new mown hay foin coupeFR
 herbalFR
 huckleberry bilberryFR
 hyssopFL/FR
 jasminFR
 leather russianFR
 licoriceFR
 magnoliaFR
 meadowsweet spiraeaFR
 mimosaFR
 mintFR
 mulberryFR
 orientalFR
 peachFR
 peppermintFR
 raspberryFR
 reseda mignonetteFR
 root beerFR
 rueFL/FR
 sarsaparillaFL
 sassafrasFR
 spearmintFR
 spiceFR
 spicewood 
 strawberryFR
 tea greenFR
 tomatoFL
 tuberoseFR
 valerianFL/FR
 wallflowerFR
 wintergreenFR
 wormwood absinthiumFL/FR
 ylang ylangFR
 zibeline 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 bilberry fruit
Search Trop  Picture
 bilberry fruit juice
Search Trop  Picture
 cassia bark
Search Trop  Picture
 cassie absolute @ 94.40%
Data  GC  Search Trop  Picture
 champaca absolute (michelia alba dc.) @ 0.02%
Data  GC  Search Trop  Picture
 champaca concrete @ 0.15%
Data  GC  Search Trop  Picture
 cherry sour cherry plant
Search Trop  Picture
 clove bud
Search Trop  Picture
 clove fruit
Search Trop  Picture
 corn leaf
Search Trop  Picture
 couroupita guianensis aubl. flower oil brazil @ 0.50%
Data  GC  Search Trop  Picture
 currant black currant fruit
Search Trop  Picture
 currant black currant leaf
Search Trop  Picture
 currant red currant fruit
Search Trop  Picture
 dialium guineense wild.fruit oil france @ 4.90%
Data  GC  Search Trop  Picture
 elder black elder flower oil
Search Trop  Picture
 elder black elder leaf oil
Search Trop  Picture
 fig leaf
Search Trop  Picture
 grape concord grape
Search  Picture
 hyacinthus orientalis absolute @ 0.04-0.07%
Data  GC  Search Trop  Picture
 hyssop shoot
Search Trop  Picture
 laurel leaf oil turkey @ trace%
Data  GC  Search Trop  Picture
 levisticum officinale seed oil @ 0.11%
Data  GC  Search Trop  Picture
 mandarin
Search Trop  Picture
 oat seed
Search Trop  Picture
 orange
Search Trop  Picture
 orthodon dianthera maxim. oil vietnam @ trace%
Data  GC  Search Trop  Picture
 papaya fruit
Search Trop  Picture
 peach fruit
Search Trop  Picture
 petitgrain mandarin oil @ trace%
Data  GC  Search Trop  Picture
 pimento berry oil @ trace%
Data  GC  Search Trop  Picture
 plum fruit
Search  Picture
 plumcot fruit
Search  Picture
 raspberry red raspberry fruit
Search Trop  Picture
 roselle calyx
Search Trop  Picture
 rue oil
Search Trop  Picture
 sage clary sage
Search Trop  Picture
 spearmint oil
Search Trop  Picture
 stachys recta l. oil serbia @ 0.20%
Data  GC  Search Trop  Picture
 strawberry wild strawberry fruit
Search Trop  Picture
 tamarind fruit
Search Trop  Picture
 tamarind seed
Search Trop  Picture
 tea leaf
Search Trop  Picture
 tomato
Search Trop  Picture
 tomato fruit
Search Trop  Picture
 vanilla
Search  Picture
 wine white wine
Search  Picture
 wintergreen leaf
Search Trop  Picture
 ylang ylang oil @ 0.29%
Data  GC  Search Trop  Picture
 ylang ylang oil CO2 extract @ 0.04%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 benzoic acid, 2-hydroxy-, methyl ester
synthetic sweet birch oil
 birch-me
2-carbomethoxyphenol
 hewedolor
2-hydroxybenzoic acid methyl ester
o-hydroxybenzoic acid methyl ester
ortho-hydroxybenzoic acid methyl ester
 linsal
2-(methoxycarbonyl) phenol
2-(methoxycarbonyl)phenol
 methyl 2-hydroxybenzoate
 methyl o-hydroxybenzoate
 methyl ortho-hydroxybenzoate
 methyl salicylate (+)
 methyl salicylate BP
 methyl salicylate extra pure
 methyl salicylate FCC
 methyl salicylate fractions
 methyl salicylate low phenol
 methyl salicylate natural
 methyl salicylate NF FCC
 methyl salicylate NF grade
 methyl salicylate synthetic
 methyl salicylate synthetic NF/FCC
 methyl salicylate USP
 methylsalicylate
 metsal liniment
 rheumabal
 rhodiaflor
 salicylic acid methyl ester
synthetic teaberry oil
synthetic wintergreen oil
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Postharvest biology and technology of pomegranate.
PubMed: Fractionation and identification of minor and aroma-active constituents in Kangra orthodox black tea.
PubMed: Role of internal atmosphere on fruit ripening and storability-a review.
PubMed: Inoculation of the nonlegume Capsicum annuum L. with Rhizobium strains. 2. Changes in sterols, triterpenes, fatty acids, and volatile compounds.
PubMed: Efficient scavenging of β-carotene radical cations by antiinflammatory salicylates.
PubMed: New chemical constituents from Oryza sativa straw and their algicidal activities against blue-green algae.
PubMed: Static liquid permeation cell method for determining the migration parameters of low molecular weight organic compounds in polyethylene terephthalate.
PubMed: Apple volatiles synergize the response of codling moth to pear ester.
PubMed: Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test.
PubMed: Profiling of volatile compounds of Phyllostachys pubescens shoots in Taiwan.
PubMed: What happens if people start drinking mouthwash as surrogate alcohol? A quantitative risk assessment.
PubMed: Volatiles from apple trees infested with light brown apple moth larvae attract the parasitoid Dolichogenidia tasmanica.
PubMed: Hull split and damaged almond volatiles attract male and female navel orangeworm moths.
PubMed: Sequence comparisons of odorant receptors among tortricid moths reveal different rates of molecular evolution among family members.
PubMed: The estrogenic potential of salicylate esters and their possible risks in foods and cosmetics.
PubMed: Methyl salicylate-induced arginine catabolism is associated with up-regulation of polyamine and nitric oxide levels and improves chilling tolerance in cherry tomato fruit.
PubMed: Vicia faba Hypersensitivity and ASA Intolerance in a Farmer: A Case Report.
PubMed: Methyl salicylate attracts natural enemies and reduces populations of soybean aphids (Hemiptera: Aphididae) in soybean agroecosystems.
PubMed: Evaluation of genotype and environment effects on taste and aroma flavor components of Spanish fresh tomato varieties.
PubMed: Leaf volatile emissions of Betula pendula during autumn coloration and leaf fall.
PubMed: Effect of methyl salicylate-based lures on beneficial and pest arthropods in strawberry.
PubMed: Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study.
PubMed: Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products.
PubMed: Elicitation of pharmacologically active substances in an intact medical plant.
PubMed: Odorant receptors from the light brown apple moth (Epiphyas postvittana) recognize important volatile compounds produced by plants.
PubMed: Oriented responses of grapevine moth larvae Lobesia botrana to volatiles from host plants and an artificial diet on a locomotion compensator.
PubMed: Field-testing of synthetic herbivore-induced plant volatiles as attractants for beneficial insects.
PubMed: Repellency of an over-the-counter essential oil product in China against workers of red imported fire ants.
PubMed: The use of a semiochemical bait to enhance exposure of Amblyomma variegatum (Acari: Ixodidae) to Metarhizium anisopliae (Ascomycota: Hypocreales).
PubMed: Floral attractants for the female soybean looper, Thysanoplusia orichalcea (Lepidoptera: Noctuidae).
PubMed: Predatory mite attraction to herbivore-induced plant odors is not a consequence of attraction to individual herbivore-induced plant volatiles.
PubMed: Fragrance material review on methyl salicylate.
PubMed: First report of an attractant for a tumbling flower beetle (Coleoptera: Mordellidae).
PubMed: Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds.
PubMed: Antifungal activities of major tea leaf volatile constituents toward Colletorichum camelliae Massea.
PubMed: Salicylate activity. 2. Potentiation of atrazine.
PubMed: Salicylate activity. 1. Protection of plants from paraquat injury.
PubMed: Stable isotope characterization of the ortho-oxygenated phenylpropanoids: coumarin and melilotol.
PubMed: Effects of cyclamen mite (Phytonemus pallidus) and leaf beetle (Galerucella tenella) damage on volatile emission from strawberry (Fragaria x ananassa Duch.) plants and orientation of predatory mites (Neoseiulus cucumeris, N. californicus, and Euseius finlandicus).
PubMed: The involvement of volatile infochemicals from spider mites and from food-plants in prey location of the generalist predatory mite Neoseiulus californicus.
PubMed: Natural abundance 2H-ERETIC-NMR authentication of the origin of methyl salicylate.
PubMed: Effect of volatile constituents from Securidaca longepedunculata on insect pests of stored grain.
PubMed: Hydrolysis of glycosidically bound volatiles from apple leaves (Cv. Anna) by Aspergillus niger beta-glucosidase affects the behavior of codling moth (Cydia pomonella L.).
PubMed: Contaminants and levels of occurrence in washed and shredded poly(ethylene terephthalate) from curbside collection. Part 1: Extraction conditions.
PubMed: Ovicidal and adulticidal effects of Eugenia caryophyllata bud and leaf oil compounds on Pediculus capitis.
PubMed: Aerosolized essential oils and individual natural product compounds as brown treesnake repellents.
PubMed: Composition of the volatiles from intact and mechanically pierced tea aphid-tea shoot complexes and their attraction to natural enemies of the tea aphid.
PubMed: Plant odor analysis of apple: antennal response of codling moth females to apple volatiles during phenological development.
PubMed: Analysis of glycosidically bound aroma precursors in tea leaves. 1. Qualitative and quantitative analyses of glycosides with aglycons as aroma compounds.
PubMed: (Z)-3-hexenyl and trans-linalool 3,7-oxide beta-primeverosides isolated as aroma precursors from leaves of a green tea cultivar.
PubMed: Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals.
PubMed: Local lymph node activation and IgE responses in brown Norway and Wistar rats after dermal application of sensitizing and non-sensitizing chemicals.
PubMed: Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate to retinol (vitamin A) during percutaneous absorption.
PubMed: Drugs in the food supply.
PubMed: Evaluation of safety for food additives: An illustration involving the influence of methyl salicylate on rat reproduction.
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