EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

acesulfame potassium
potassium salt of 3,4-dihydro-6-methyl-1,2,3-oxathiazine-4-one-2,2-dioxide

Sponsors

CAS Number: 55589-62-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:259-715-3
FDA UNII:23OV73Q5G9
Nikkaji Web:J269.091H
MDL:MFCD00043833
Molecular Weight:201.24298000
Formula:C4 H4 K N O4 S
NMR Predictor:Predict (works with chrome or firefox)
Category:sweeteners, flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Additive: Acesulfame Potassium
GSFA Codex: Acesulfame potassium (950)
DG SANTE Food Additives:acesulfame K
FDA Mainterm: ACESULFAME POTASSIUM
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.800 Acesulfame potassium.
 
Physical Properties:
Appearance:white crystalline powder (exp)
Assay: 95.00 to 100.00
Heavey Metals:< 1 mg/kg Pb
Halogens:< 3 mg/kg F
Food Chemicals Codex Listed: No
Boiling Point: 332.00 to 334.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.000001 mm/Hg @ 25.00 °C. (est)
Flash Point: 311.00 °F. TCC ( 155.00 °C. )
logP (o/w): -0.310 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 alcohol, very slightly
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor Type: odorless
Odor Strength:none
Odor Description:at 100.00 %. odorless
Flavor Type: sweet
sweet sugar candy
Taste Description: sweet sugar candy
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
 
Suppliers:
AIDP
Acesulfame K Ace-k 99% - 101%
Anhui Haibei
Acesulfame-k
Anhui Jinghe
Acesulfame-k or Acesulfame Potassium
Atlantic Chemicals
Acesulfame-K
BOC Sciences
For experimental / research use only.
Acesulfame Potassium >98%
Odor: characteristic
Use: Acesulfame potassium is a non-nutritive sweetener.
ECSA Chemicals
Acesulfame-K
Company Profile
Foodchem International
Acesulfame-K
Graham Chemical
Acesulfame Potassium
Jiangyin Healthway
Acesulfame Potassium
New functional food ingredients
Kraft Chemical
Acesulfame K
Kunshan Sainty
Acesulfame K, Kosher
Norman, Fox & Co.
ACE-K
Northwestern Extract
Ace-K
OQEMA
Acesulfame K
Penta International
ACESULFAME K, Kosher, Halal
Prinova
Acesulfame Potassium
Qingdao Dacon Trading
Ace-K
Sigma-Aldrich
For experimental / research use only.
Acesulfame K for food analysis, ≥99.0%
Silver Fern Chemical
Acesulfame Potassium
Odor: characteristic
Use: Acesulfame potassium is primarily used in the food and beverage industry. It occasionally is used in personal care products such as toothpaste, as well as certain vitamins and supplements.
Sinofi Food Ingredients
Acesulfame Potassium
Flavor: characteristic
Sugar Substitutes, Chewing Gum, Dairy Products, Confections, Baking Food, Yogurt, Desserts, Alcoholic Beverages, Beverage Powder, Instant Coffee, Chai Tea, Gelatins, Puddings, Ice Cream, Cosmetics, Feed, Pharmaceutical.
TCI AMERICA
For experimental / research use only.
Acesulfame K >97.0%(T)
The Ingredient House
RightSweet Acesulfame K
Universal Preserv-A-Chem Inc.
ACESULFAME K (Potassium) FCC Kosher
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: sweeteners, flavor enhancers
Recommendation for acesulfame potassium usage levels up to:
 not for fragrance use.
 
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety of the proposed extension of use of acesulfame K (E 950) in foods for special medical purposes in young children
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23683747
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
potassium 6-methyl-2,2-dioxooxathiazin-4-olate
Chemidplus:0055589623
 
References:
 potassium 6-methyl-2,2-dioxooxathiazin-4-olate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:55589-62-3
Pubchem (cid):23683747
Pubchem (sid):135019383
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB33955
FooDB:FDB012173
Export Tariff Code:2934.99.9000
FDA Listing of Food Additive Status:View
Household Products:Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
acidic
cyclohexyl acetic acid
FL/FR
aldehydic
citronellyl oxyacetaldehyde
FL/FR
animal
para-
cresyl phenyl acetate
FL/FR
anisic
para-
anisyl phenyl acetate
FL/FR
balsamic
2-
acetyl furan
FL/FR
guaiacyl phenyl acetate
FL/FR
2-
phenyl propyl alcohol
FL/FR
buttery
acetoin
FL/FR
acetyl propionyl
FL/FR
3,4-
hexane dione
FL/FR
caramellic
2-iso
butyl-3-methyl pyrazine
FL/FR
2-oxo
butyric acid
FL/FR
caramel pentadione
FL/FR
coffee dione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
diethyl malate
FL/FR
alpha,alpha-
dimethyl anisyl acetone
FL/FR
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
ethyl cyclopentenolone
FL/FR
ethyl maltol
FL/FR
5-
ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR
fenugreek absolute
FL/FR
immortelle absolute
FL/FR
levulinic acid
FL/FR
maltol
FL/FR
maltyl isobutyrate
FL/FR
maltyl propionate
FL/FR
maple furanone
FL/FR
menthone lactone
FL/FR
5-
methyl furfural
FL/FR
iso
propenyl pyrazine
FL/FR
rosefuran
FL/FR
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
toffee furanone
FL/FR
chocolate
iso
amyl phenyl acetate
FL/FR
cocoa pentenal
FL/FR
tetrahydrofurfuryl phenyl acetate
FL/FR
coconut
gamma-
heptalactone
FL/FR
creamy
gamma-
butyrolactone
FL/FR
ethereal
ethyl 4-pentenoate
FL/FR
ethyl pyruvate
FL/FR
fatty
methyl (E)-2-hexenoate
FL/FR
fermented
ethyl (E)-2-crotonate
FL/FR
floral
cardamom absolute
FL/FR
citronellyl phenyl acetate
FL/FR
citronellyl valerate
FL/FR
beta-
damascenone
FL/FR
ethyl hydrocinnamate
FL/FR
ethyl phenyl acetate
FL/FR
geranyl phenyl acetate
FL/FR
heliotropyl acetone
FL/FR
hyacinth acetals
FL/FR
linalyl phenyl acetate
FL/FR
ortho-
methyl acetophenone
FL/FR
octyl isovalerate
FL/FR
bitter
orangeflower absolute morocco
FL/FR
phenethyl acetate
FL/FR
phenethyl anthranilate
FL/FR
phenethyl benzoate
FL/FR
phenethyl hexanoate
FL/FR
phenethyl phenyl acetate
FL/FR
phenethyl propionate
FL/FR
3-
phenyl propyl formate
FL/FR
iso
propyl anthranilate
FL/FR
iso
propyl phenyl acetate
FL/FR
rhodinyl phenyl acetate
FL/FR
rose absolute (rosa centifolia) morocco
FL/FR
tuberose absolute (from concrete)
FL/FR
tuberose absolute (from pommade)
FL/FR
fruity
allyl phenoxyacetate
FL/FR
cyclohexyl acetate
FL/FR
beta-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
(Z)-beta-
damascone
FL/FR
(E)-
ethyl tiglate
FL/FR
(Z)-3-
octen-1-yl propionate
FL/FR
osmanthus flower absolute
FL/FR
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
strawberry glycidate 2
FL/FR
tetrahydrofurfuryl acetate
FL/FR
green
iso
amyl 3-(2-furan) propionate
FL/FR
(E)-2-
hexen-1-yl phenyl acetate
FL/FR
(Z,Z)-3,6-
nonadien-1-ol
FL/FR
phenyl acetaldehyde
FL/FR
hay
beeswax absolute
FL/FR
herbal
artemisyl ketone
FL/FR
butyl levulinate
FL/FR
matricaria chamomilla flower oil
FL/FR
wormwood oil america
FL/FR
wormwood oil america
FL/FR
wormwood oil cuba
FL/FR
wormwood oil cuba
FL/FR
wormwood oil italy
FL/FR
wormwood oil italy
FL/FR
wormwood oil poland
FL/FR
wormwood oil poland
FL/FR
honey
allyl phenyl acetate
FL/FR
butyl phenyl acetate
FL/FR
methyl hydrocinnamate
FL/FR
methyl phenyl acetate
FL/FR
phenethyl furoate
FL/FR
phenyl acetic acid
FL/FR
phenyl pyruvic acid
FL/FR
propyl phenyl acetate
FL/FR
melon
(Z)-6-
nonen-1-ol
FL/FR
musty
3-
acetyl-2,5-dimethyl furan
FL/FR
cocoa butenal
FL/FR
nutty
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
2,3-
dimethyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
phenolic
4-
methyl-2,6-dimethoxyphenol
FL/FR
spicy
cinnamaldehyde
FL/FR
iso
eugenyl phenyl acetate
FL/FR
eugenyl phenyl acetate
FL/FR
(E)-
tiglic acid
FL/FR
sweet
vanilla oleoresin bali
FL/FR
thujonic
cistus cyclohexanone
FL/FR
vanilla
ethyl vanillin
FL/FR
vanillyl isobutyrate
FL/FR
vanillyl isobutyrate
FL/FR
vegetable
tetrahydrofurfuryl alcohol
FL/FR
waxy
1-
dodecanol
FL/FR
methyl butyl phenyl acetate
FL/FR
woody
santalyl phenyl acetate
FL/FR
For Flavor
No flavor group found for these
1-
acetyl cyclohexyl acetate
FL
2-
acetyl-3,4,5,6-tetrahydropyridine
FL
allyl 2-furoate
FL
artemisyl ketone
FL/FR
benzyl disulfide
FL
cistus cyclohexanone
FL/FR
citronellyl valerate
FL/FR
diethyl malate
FL/FR
2,5-
diethyl tetrahydrofuran
FL
alpha,alpha-
dimethyl anisyl acetone
FL/FR
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
ethyl 4-pentenoate
FL/FR
ethyl hydrocinnamate
FL/FR
5-
ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR
eugenyl phenyl acetate
FL/FR
fig leaf absolute
FL
furfuryl acetone
FL
(E)-2-
hexen-1-yl phenyl acetate
FL/FR
linalyl phenyl acetate
FL/FR
mango furanone
FL
menthone lactone
FL/FR
methyl (E)-2-hexenoate
FL/FR
methyl hydrocinnamate
FL/FR
octyl isovalerate
FL/FR
osmanthus flower absolute
FL/FR
phenethyl furoate
FL/FR
3-
phenyl propyl formate
FL/FR
iso
propyl anthranilate
FL/FR
rosefuran
FL/FR
santalyl phenyl acetate
FL/FR
tetrahydrofurfuryl phenyl acetate
FL/FR
iso
amyl 3-(2-furan) propionate
FL/FR
beta-
damascone
FL/FR
acidic
acidic
levulinic acid
FL/FR
dextro,laevo-
tartaric acid
FL
anisic
para-
anisyl phenyl acetate
FL/FR
ortho-
methyl acetophenone
FL/FR
aromatic
hyacinth acetals
FL/FR
berry
heliotropyl acetone
FL/FR
brown
beeswax absolute
FL/FR
2-oxo
butyric acid
FL/FR
5-
methyl furfural
FL/FR
tetrahydrofurfuryl acetate
FL/FR
(E)-
tiglic acid
FL/FR
burnt
furfuryl alcohol
FL
iso
propenyl pyrazine
FL/FR
buttery
diacetyl
FL
3,4-
hexane dione
FL/FR
caramellic
caramel furanone
FL
caramel pentadione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
ethyl maltol
FL/FR
5-
ethyl-3,4,5,6-tetramethyl cyclohexen-2-one
FL
fenugreek absolute
FL/FR
maltol
FL/FR
maltyl propionate
FL/FR
maple furanone
FL/FR
3-
methyl butyl 2-furyl butyrate
FL
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
toffee furanone
FL/FR
citrus
citronellyl oxyacetaldehyde
FL/FR
coffee
coffee dione
FL/FR
2-
thiophene thiol
FL
creamy
acetoin
FL/FR
2-
propanoyl thiophene
FL
fatty
(E,E)-2,4-
undecadienal
FL
2,4-
undecadienal
FL
floral
iso
amyl phenyl acetate
FL/FR
cardamom absolute
FL/FR
citronellyl phenyl acetate
FL/FR
cocoa pentenal
FL/FR
geranyl phenyl acetate
FL/FR
methyl phenyl acetate
FL/FR
bitter
orangeflower absolute morocco
FL/FR
phenethyl anthranilate
FL/FR
phenethyl benzoate
FL/FR
phenethyl propionate
FL/FR
phenyl acetic acid
FL/FR
rose absolute (rosa centifolia) morocco
FL/FR
tuberose absolute (from concrete)
FL/FR
tuberose absolute (from pommade)
FL/FR
fruity
allyl phenoxyacetate
FL/FR
(Z)-beta-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
(E)-
ethyl tiglate
FL/FR
furfuryl valerate
FL
(Z)-3-
octen-1-yl propionate
FL/FR
2-
pentanoyl furan
FL
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
strawberry glycidate 2
FL/FR
green
2-iso
butyl-3-methyl pyrazine
FL/FR
cocoa butenal
FL/FR
(E)-3-
hexenoic acid
FL
immortelle absolute
FL/FR
2-
phenyl propyl alcohol
FL/FR
herbal
butyl levulinate
FL/FR
5-
hydroxymethyl furfural
FL
matricaria chamomilla flower oil
FL/FR
wormwood oil america
FL/FR
wormwood oil america
FL/FR
wormwood oil cuba
FL/FR
wormwood oil cuba
FL/FR
wormwood oil italy
FL/FR
wormwood oil italy
FL/FR
wormwood oil poland
FL/FR
wormwood oil poland
FL/FR
honey
allyl phenyl acetate
FL/FR
butyl phenyl acetate
FL/FR
ethyl phenyl acetate
FL/FR
phenethyl acetate
FL/FR
phenethyl phenyl acetate
FL/FR
phenyl acetaldehyde
FL/FR
propyl phenyl acetate
FL/FR
iso
propyl phenyl acetate
FL/FR
jammy
ethyl cyclopentenolone
FL/FR
maltyl isobutyrate
FL/FR
lactonic
gamma-
heptalactone
FL/FR
leafy
methyl butyl phenyl acetate
FL/FR
meaty
2-
mercaptomethyl pyrazine
FL
milky
gamma-
butyrolactone
FL/FR
musty
ethyl (E)-2-crotonate
FL/FR
nutty
2-
acetyl furan
FL/FR
3-
acetyl-2,5-dimethyl furan
FL/FR
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
3,5(6)-
cocoa pyrazine
FL
2,3-
dimethyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
peanut oxazole
FL
tetrahydrofurfuryl alcohol
FL/FR
phenolic
para-
cresyl phenyl acetate
FL/FR
guaiacyl phenyl acetate
FL/FR
4-
methyl-2,6-dimethoxyphenol
FL/FR
phenyl pyruvic acid
FL/FR
rummy
ethyl pyruvate
FL/FR
soapy
1-
dodecanol
FL/FR
solvent
cyclohexyl acetate
FL/FR
sour
2,4-
dimethyl-2-pentenoic acid
FL
spicy
cinnamaldehyde
FL/FR
iso
eugenyl phenyl acetate
FL/FR
sweet
alitame anhydrous
FL
aspartame
FL
aspartame-acesulfame salt
FL
caramel dione
FL
cyclohexyl acetic acid
FL/FR
dextro-
sorbitol
FL
thaumatin
FL
vanilla oleoresin bali
FL/FR
toasted
acetyl propionyl
FL/FR
vanilla
ethyl vanillin
FL/FR
vanillyl isobutyrate
FL/FR
vanillyl isobutyrate
FL/FR
waxy
furfuryl octanoate
FL
(Z,Z)-3,6-
nonadien-1-ol
FL/FR
(Z)-6-
nonen-1-ol
FL/FR
phenethyl hexanoate
FL/FR
rhodinyl phenyl acetate
FL/FR
woody
beta-
damascenone
FL/FR
 
Potential Uses:
 masking agents
 oral care agents
 sweetener
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ace K
 acesulfame K
 acesulfame potassium
6-methyl-1,2,3-oxathiazin-4 -one2,2-dioxidepotassiumsalt
6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt
6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide, potassium salt
6-methyl-1,2,3-oxathiazin-4(3H)-one2,2-dioxidepotassiumsalt
6-methyl-3H-1,2,3-oxathiazine-2,2,4-trione, potassium salt
1,2,3-oxathiazin-4-ol, 6-methyl-, 2,2-dioxide, potassium salt (1:1)
1,2,3-oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide, potassium salt
 potassium 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide
 potassium 6-methyl-2,2-dioxooxathiazin-4-olate
 potassium 6-methyl-4-oxo-4H-1,2,3-oxathiazin-3-ide 2,2-dioxide
 potassium acesulfame
 potassium salt of 3,4-dihydro-6-methyl-1,2,3-oxathiazine-4-one-2,2-dioxide
 potassium salt of 6-methyl-1,2,3-oxathiazine-4(3H)-one-2,2-dioxide
 

Articles:

PubMed:Spatial characteristics of professional tennis serves with implications for serving aces: A machine learning approach.
PubMed:Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans.
PubMed:[Development of a New Method for Determination of Sodium Saccharin and Acesulfame Potassium with the Aid of Coagulant].
PubMed:Nonnutritive Sweeteners in Breast Milk.
PubMed:[Association between non-nutritive sweeteners and obesity risk among university students in Latin America].
PubMed:Simultaneous determination of sweeteners in beverages by LC-MS/MS.
PubMed:[Consumption of carbonated beverages with nonnutritive sweeteners in Latin American university students].
PubMed:Acesulfame-K and pharmaceuticals as co-tracers of municipal wastewater in a receiving river.
PubMed:Quantification of acesulfame potassium in processed foods by quantitative 1H NMR.
PubMed:Allergic reaction caused by acesulfame potassium in foods.
PubMed:[Modification of fasting blood glucose in adults with diabetes mellitus type 2 after regular soda and diet soda intake in the State of Querétaro, Mexico].
PubMed:Precise measurement for the purity of amino acid and peptide using quantitative nuclear magnetic resonance.
PubMed:Sweet Taste-Sensing Receptors Expressed in Pancreatic ő≤-Cells: Sweet Molecules Act as Biased Agonists.
PubMed:Effects of three intense sweeteners on fat storage in the C. elegans model.
PubMed:[A rapid dialysis method for analysis of artificial sweeteners in food].
PubMed:[Comprehensive evaluation of palatability for commercial medicine by taste sensing system].
PubMed:A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides.
PubMed:Ingestion of bacterial lipopolysaccharide inhibits peripheral taste responses to sucrose in mice.
PubMed:Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors.
PubMed:Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice.
PubMed:Bitterness of the non-nutritive sweetener acesulfame potassium varies with polymorphisms in TAS2R9 and TAS2R31.
PubMed:Effect of sweeteners and hydrocolloids on quality attributes of reduced-calorie carrot juice.
PubMed:Lack of functionally active sweet taste receptors in the jejunum in vivo in the rat.
PubMed:Validation of the Korean Addenbrooke's Cognitive Examination for diagnosing Alzheimer's dementia and mild cognitive impairment in the Korean elderly.
PubMed:Bitterness prediction of H1-antihistamines and prediction of masking effects of artificial sweeteners using an electronic tongue.
PubMed:Effect of the artificial sweetener, acesulfame potassium, a sweet taste receptor agonist, on glucose uptake in small intestinal cell lines.
PubMed:Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors.
PubMed:Metabolic acidosis mimicking diabetic ketoacidosis after use of calorie-free mineral water.
PubMed:Angiotensin I-converting enzyme inhibitory proteins and peptides from the rhizomes of Zingiberaceae plants.
PubMed:Inhibitory activities of baicalin against renin and angiotensin-converting enzyme.
PubMed:[Simultaneous determination of six food additives in meat products by high performance liquid chromatography].
PubMed:Rational development of taste masked oral liquids guided by an electronic tongue.
PubMed:An electronic tongue: evaluation of the masking efficacy of sweetening and/or flavoring agents on the bitter taste of epinephrine.
PubMed:Inadequate toxicity tests of food additive acesulfame.
PubMed:General and persistent effects of high-intensity sweeteners on body weight gain and caloric compensation in rats.
PubMed:Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.
PubMed:NTP toxicology studies of acesulfame potassium (CAS No. 55589-62-3) in genetically modified (FVB Tg.AC Hemizygous) mice and carcinogenicity studies of acesulfame potassium in genetically modified [B6.129-Trp53(tm1Brd) (N5) Haploinsufficient] mice (feed studies)mice.
PubMed:Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2.
PubMed:Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives.
PubMed:Testing needed for acesulfame potassium, an artificial sweetener.
PubMed:Action mechanism of an angiotensin I-converting enzyme inhibitory peptide derived from chicken breast muscle.
PubMed:[Analysis of nine kinds of sweeteners in foods by LC/MS].
PubMed:Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20s proteasome inhibitor, clasto-lactacystin beta-lactone.
PubMed:Scope of the reductive aldol reaction: application to aromatic carbocycles and heterocycles.
PubMed:The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets.
PubMed:Determination of acesulfame and sucralose in oral electrolyte maintenance solution by liquid chromatography.
PubMed:[Simultaneous determination of various food additives by high performance liquid chromatography].
PubMed:Gustatory responses of the hamster Mesocricetus auratus to various compounds considered sweet by humans.
PubMed:Noncariogenic intense natural sweeteners.
PubMed:Gustatory neural coding in the monkey cortex: the quality of sweetness.
 
Notes:
ADI 15 mg/kg (1991). Intense-type sweetener permitted at 300-5500 ppm in foods. Sweetness approx. 200 x sucrose Acesulfame potassium is a calorie-free artificial sweetener, also known as Acesulfame K or Ace K (K being the symbol for potassium), and marketed under the trade names Sunett and Sweet One. In the European Union, it is known under the E number (additive code) E950. It was discovered accidentally in 1967 by German chemist Karl Clauss at Hoechst AG (now Nutrinova). In chemical structure, acesulfame potassium is the potassium salt of 6-methyl-1,2,3- oxathiazine-4(3H)-one 2,2-dioxide. It is a white crystalline powder with molecular formula C4H4KNO4S and a molecular weight of 201.24.
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