EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

laevo-carveol
carveol

Supplier Sponsors

Name:2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
CAS Number: 99-48-9Picture of molecule3D/inchi
Other(deleted CASRN):20307-86-2
ECHA EINECS - REACH Pre-Reg:202-757-4
FDA UNII: Search
Beilstein Number:1861032
MDL:MFCD00062993
CoE Number:2027
XlogP3-AA:2.10 (est)
Molecular Weight:152.23672000
Formula:C10 H16 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:381 carveol
DG SANTE Food Flavourings:02.062 carveol
FEMA Number:2247 carveol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):99-48-9 ; CARVEOL
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity:0.94700 to 0.95300 @ 25.00 °C.
Pounds per Gallon - (est).: 7.880 to 7.930
Refractive Index:1.49300 to 1.49700 @ 20.00 °C.
Boiling Point: 226.00 to 227.00 °C. @ 751.00 mm Hg
Vapor Pressure:0.011700 mmHg @ 25.00 °C. (est)
Flash Point: 209.00 °F. TCC ( 98.33 °C. )
logP (o/w): 3.120
Soluble in:
 alcohol
 water, 519.7 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: minty
Odor Strength:medium
Substantivity:51 hour(s) at 100.00 %
minty spearmint cooling green herbal caraway spicy
Odor Description:at 100.00 %. minty spearmint cooling green herbal caraway spicy
Luebke, William tgsc, (2021)
Odor sample from: Vigon International
Flavor Type: minty
minty green weedy herbal plastic spicy earthy mahogany
Taste Description: minty green weedy herbal plastic spicy earthy mahogany
Luebke, William tgsc, (2021)
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
ACS International
Carveol-L
Odor: spearmint caraway
Operational Capabilities
BOC Sciences
For experimental / research use only.
laevo-Carveol
ExtraSynthese
For experimental / research use only.
(-)-Carveol
Fleurchem
l-carveol natural
Frutarom
L-CARVEOL
KOSHER
Flavor: Minty, Caraway, Spearmint
CBD Offering
IFF
L-CARVEOL
KOSHER
Flavor: Minty, Caraway, Spearmint
M&U International
Laevo Carveol
Nippon Terpene Chemicals
l-Carveol 96% up
Penta International
L-CARVEOL FCC
Penta International
L-CARVEOL NATURAL
Penta International
L-CARVEOL
R C Treatt & Co Ltd
Carveol
Santa Cruz Biotechnology
For experimental / research use only.
Carveol ≥96%
Sigma-Aldrich
L-Carveol, mixture of cis and trans, ≥95%, FG
Odor: herbaceous; minty
Certified Food Grade Products
Synerzine
L-CARVEOL
Vigon International
Carveol Laevo FCC
Odor: Spearmint caraway
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 3000 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 1055, 1973.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 1055, 1973.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for laevo-carveol usage levels up to:
  4.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 9.50 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 140.00 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: 3.000005.00000
beverages(nonalcoholic): 1.5000013.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -3.00000
fruit ices: -3.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 3.0000039.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 212: alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19
View page or View pdf

Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 212 Revision 1 (FGE.212Rev1): alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19.
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 212 Revision 3 (FGE.212Rev3): a,ß-unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):99-48-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7438
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
Chemidplus:0000099489
EPA/NOAA CAMEO:hazardous materials
RTECS:OS8400000 for cas# 99-48-9
 
References:
Leffingwell:Chirality or Article
 2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:99-48-9
Pubchem (cid):7438
Pubchem (sid):134971745
Flavornet:99-48-9
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
UM BBD:Search
HMDB (The Human Metabolome Database):HMDB36083
FooDB:FDB014919
Export Tariff Code:2906.19.0000
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
para-
menth-1-en-9-al
FL/FR
aldehydic
aldehydic
agrumen nitrile
FR
cheesy
2-
heptanone
FL/FR
earthy
3-
octanol
FL/FR
3-
octen-2-one
FL/FR
floral
coriander seed oil
FL/FR
dihydrojasmone
FL/FR
fruity
perillyl acetate
FL/FR
green
carrot leaf oil (daucus carota ssp.maximus)
FR
3-
hepten-2-one
FL/FR
herbal
anethum graveolens herb oil
FL/FR
carum carvi fruit oil
FL/FR
coriander seed absolute
FL/FR
coriander seed concrete
FR
dehydroxylinalool oxide
FL/FR
dill seed oil CO2 extract indian
FL/FR
dill seed oil indian
FL/FR
3-
nonanol
FL/FR
curled
parsley seed oil
FL/FR
minty
betula lenta bark oil america
FL/FR
laevo-
carvone
FL/FR
dextro-
carvone
FL/FR
cis-
carvone-5,6-oxide
FL/FR
carvyl acetate
FL/FR
dihydrocarveol
FL/FR
dextro-
dihydrocarvone
FL/FR
trans-para-
menthan-2-one
FL/FR
spearmint absolute
FL/FR
spearmint oil america
FL/FR
spearmint oil terpeneless
FL/FR
tetrahydrocarvone
FL/FR
spicy
iso
butyl (E,E)-2,4-decadienamide
FL/FR
iso
butyl angelate
FL/FR
carrot weed oil
FL/FR
carvacryl ethyl ether
FL/FR
trans-
carveol
FL/FR
cis-
carveol
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
N,N-
diethyl octanamide
FR
ginger oleoresin africa
FL/FR
origanum majorana oil
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
4-iso
propyl-2-cyclohexenone
FL/FR
laevo-
verbenone
FL/FR
tonka
mint lactone
FL/FR
For Flavor
No flavor group found for these
iso
butyl (E,E)-2,4-decadienamide
FL/FR
carvacryl ethyl ether
FL/FR
cis-
carveol
FL/FR
trans-
carveol
FL/FR
2,4-
dimethyl anisole
FL
para-
menth-1-en-9-al
FL/FR
cis+trans-para-1(7)8-
menthadien-2-yl acetate
FL
3-
nonanol
FL/FR
4-iso
propyl-2-cyclohexenone
FL/FR
laevo-
verbenone
FL/FR
hexyl 3-mercaptobutanoate
FL
cheesy
cheesy
2-
heptanone
FL/FR
creamy
3-
hepten-2-one
FL/FR
mint lactone
FL/FR
3-
octen-2-one
FL/FR
floral
dihydrojasmone
FL/FR
green
iso
butyl angelate
FL/FR
carrot weed oil
FL/FR
dihydrocarveol
FL/FR
dextro-
dihydrocarvone
FL/FR
perillyl acetate
FL/FR
herbal
anethum graveolens herb oil
FL/FR
carum carvi fruit oil
FL/FR
coriander seed absolute
FL/FR
coriander seed oil
FL/FR
origanum majorana oil
FL/FR
curled
parsley seed oil
FL/FR
meaty
2-
methyl 3-(methyl thio) furan
FL
minty
betula lenta bark oil america
FL/FR
laevo-
carvone
FL/FR
dextro-
carvone
FL/FR
cis-
carvone-5,6-oxide
FL/FR
carvyl acetate
FL/FR
trans-para-
menthan-2-one
FL/FR
spearmint absolute
FL/FR
spearmint oil america
FL/FR
spearmint oil terpeneless
FL/FR
tetrahydrocarvone
FL/FR
musty
3-
octanol
FL/FR
spicy
cinnamaldehyde dimethyl acetal
FL/FR
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
dill seed oil CO2 extract indian
FL/FR
dill seed oil indian
FL/FR
ginger oleoresin africa
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
woody
dehydroxylinalool oxide
FL/FR
 
Potential Uses:
FL/FRcaraway seed
FL/FRdill weed
FRherbal
FRmint
FRspearmint
 
Occurrence (nature, food, other):note
 caraway oil
Search Trop Picture
 caraway plant
Search Trop Picture
 caraway seed
Search Trop Picture
 caraway seed oil
Search Trop Picture
 celery plant
Search Trop Picture
 celery seed oil CO2 extract india @ 0.01%
Data GC Search Trop Picture
 celery seed oil india @ 0.06%
Data GC Search Trop Picture
 cumin seed
Search Trop Picture
 cypress cone oil egypt @ 0.3%
Data GC Search Trop Picture
 dill leaf
Search Trop Picture
 grapefruit oil c.p. @ 0.05%
Data GC Search Trop Picture
 grapefruit oil c.p. @ 0.05%
Data GC Search Trop Picture
 grapefruit oil c.p. @ 0.05%
Data GC Search Trop Picture
 grapefruit oil c.p. italy @ 0.10%
Data GC Search Trop Picture
 grapefruit oil CO2 extract @ 0.03%
Data GC Search Trop Picture
 lemon oil
Search Trop Picture
 lemon petiole
Search Trop Picture
 mandarin
Search Trop Picture
 orange peel oil bitter china @ 0.05%
Data GC Search Trop Picture
 parsley leaf
Search Trop Picture
 peppermint oil
Search Trop Picture
 pimenta racemosa leaf oil lemon @ 0.12%
Data GC Search Trop Picture
 rugula herb
Search Trop Picture
 spearmint oil
Search Trop Picture
 zingiber officinale root oil china @ 0.05%
Data GC Search Trop Picture
 
Synonyms:
(1R,5R)-(-)-cis-carveol
(1R)-cis-carveol
L-carveol
L-carveol FCC
 carveol laevo FCC
L-carveol natural
2-cyclohexen-1-ol, 2-methyl-5-(1-methylethenyl)-, (1R-cis)-
2-cyclohexen-1-ol, 2-methyl-5-(1-methylethenyl)-, (1R,5R)-
p-mentha-1,8-dien-6-ol
p-mentha-1(6),8-dien-2-ol
para-mentha-1(6),8-dien-2-ol
L-p-mentha-6-8-dien-2-ol
laevo-para-mentha-6-8-dien-2-ol
p-mentha-6,8-dien-2-ol
para-mentha-6,8-dien-2-ol
6,8(9)-p-menthadien-2-ol
6,8(9)-para-menthadien-2-ol
1-methyl-4-isopropenyl-6-cyclohexen-2-ol
2-methyl-5-(1-methyl ethenyl)-2-cyclohexen-1-ol
2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol
(1R-cis)-2-methyl-5-(1-methylvinyl)cyclohex-2-en-1-ol
(1R-cis)-2-methyl-5-isopropenyl-2-cyclohexen-1-ol
2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
 
 
Notes:
prolongs tumor latency and decreases tumor yield. Present in oil of grapefruit (Citrus paradisi), mandarin (Citrus reticulata), blackcurrant berries, celery, black tea, dill, caraway seeds and lamb's lettuce. Flavouring agent
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