EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

(±)-N,N-dimethyl menthyl succinamide
(1R,2S,5R)-N,N-dimethyl menthyl succinamide

Supplier Sponsors

Name:[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl] 4-(dimethylamino)-4-oxo-butanoate
CAS Number: 544714-08-1Picture of molecule3D/inchi
FDA UNII:8O850QYR5T
XlogP3-AA:3.00 (est)
Molecular Weight:282.42750000
Formula:C16 H30 N2 O2
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
Register name to be changed to (1R,2S,5R) N,NDimethyl menthyl succinamide.
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:1602 (+/-)-N,N-dimethyl menthyl succinamide
FLAVIS Number:16.092 (Old)
DG SANTE Food Flavourings:16.092 (1R,2S,5R)-N,N-dimethyl menthyl succinamide
FEMA Number:4230 (+/-)-N,N-dimethyl menthyl succinamide
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: (+/-)-N,N-DIMETHYL MENTHYL SUCCINAMIDE
 
Physical Properties:
Appearance:yellow to orange clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.96500 to 0.97500 @ 25.00 °C.
Pounds per Gallon - (est).: 8.030 to 8.113
Refractive Index:1.52200 to 1.53000 @ 20.00 °C.
Boiling Point: 380.00 °C. @ 760.00 mm Hg
Acid Value: 3.00 max. KOH/g
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 3.633 (est)
Soluble in:
 alcohol
 water, slightly
 water, 13.96 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Description:cool minty
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Axsyn
For experimental / research use only.
N,N-DIMETHYLMENTHYLSUCCINAMIDE
Parchem
(±)-N,N-Dimethyl Menthyl Succinamide
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for (±)-N,N-dimethyl menthyl succinamide usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 61.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 88.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 15000 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 100.00000300.00000
beverages(alcoholic): 100.00000300.00000
breakfast cereal: --
cheese: --
chewing gum: 4000.000008000.00000
condiments / relishes: --
confectionery froastings: 400.000001000.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: 20.0000050.00000
gelatins / puddings: 20.00000100.00000
granulated sugar: --
gravies: --
hard candy: 800.000002000.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 100.00000500.00000
snack foods: 30.00000200.00000
soft candy: 800.000002000.00000
soups: --
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 0.400004.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 0.400004.00000
Edible ices, including sherbet and sorbet (03.0): 0.400004.00000
Processed fruit (04.1): --
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 40.00000400.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): 4.0000040.00000
Meat and meat products, including poultry and game (08.0): 0.400004.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 0.400004.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 0.400004.00000
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 40.00000400.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 40.00000400.00000
Ready-to-eat savouries (15.0): 0.400004.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 0.400004.00000
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 86, (FGE.86)[1] - Consideration of aliphatic and aromatic amines and amides evaluated by JECFA (65th meeting) - Scientific Opinion of the Panel on Food Additives - Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 86, Revision 1 (FGE.86Rev1): Consideration of aliphatic and aromatic amines and amides evaluated by JECFA (65th meeting)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 86, Revision 2 (FGE.86Rev2): Consideration of aliphatic and arylalkyl amines and amides evaluated by JECFA (65th meeting)
View page or View pdf

EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :71049629
National Institute of Allergy and Infectious Diseases:Data
[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl] 4-(dimethylamino)-4-oxo-butanoate
Chemidplus:0544714081
 
References:
Leffingwell:Chirality or Article
 [(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl] 4-(dimethylamino)-4-oxo-butanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):71049629
Pubchem (sid):163642448
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):HMDB32236
FooDB:FDB009318
ChemSpider:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
camel grass oil
FR
cyclopentanone
FL/FR
laevo-mono
menthyl glutarate
FL/FR
laevo-
menthyl methyl ether
FL/FR
pinocarvone
FL/FR
aldehydic
aldehydic
iso
butyraldehyde
FL/FR
anisic
estragole
FL/FR
camphoreous
dextro-
camphor
FL/FR
camphor tree bark oil
FL/FR
herbal ethanone
FR
thujyl alcohol
FL/FR
citrus
ocimene quintoxide
FL/FR
earthy
3-
octanol
FL/FR
patchouli cyclohexanol
FR
floral
citronellal diisotridecyl acetal
FR
cyclohexyl ethyl acetate
FL/FR
cyclohexyl propanol
FR
2-
decalinol
FR
dihydrocarvyl acetate
FL/FR
2',4'-
dimethyl acetophenone
FL/FR
earthy indane
FR
floral methanol
FR
geranium oil china
FL/FR
menthadienyl formate
FR
muguet butanol
FR
ylang ylang flower oil CO2 extract
FL/FR
ylang ylang flower oil I
FL/FR
ylang ylang flower oil II
FL/FR
ylang ylang flower oil III
FL/FR
fruity
2-
cyclopentyl cyclopentanone
FL/FR
lilac lactone
FL/FR
green
geranium absolute
FL/FR
thiogeraniol
FL/FR
herbal
barosma betulina leaf oil
FL/FR
1,4-
cineole
FL/FR
dehydroxylinalool oxide
FL/FR
iso
dihydrolavandulol
FR
(Z)-iso
dihydrolavandulyl acetate
FR
herbal undecanol
FR
hyssop oil
FL/FR
para-
menthane-3,8-diol
FL/FR
myrtenol
FL/FR
perillaldehyde
FL/FR
pine hexanol
FR
D-(+)-alpha-
pinene
FL/FR
piperitone
FL/FR
rosemary absolute
FL/FR
rosemary oil morocco
FL/FR
sabinene hydrate
FL/FR
viridiflorol
FL/FR
licorice
sweet
basil oleoresin
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro,laevo-
menthol
FL/FR
laevo-
menthol
FL/FR
dextro-neo
menthol
FL/FR
(±)-iso
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
menthyl acetate
FL/FR
menthyl acetate racemic
FL/FR
peppermint cyclohexanone
FL/FR
dextro-
piperitone
FL/FR
minty
agathosma crenulata leaf oil
FL/FR
laevo-
carveol
FL/FR
laevo-
carvone
FL/FR
carvone
FL/FR
carvyl propionate
FL/FR
cyclohexanone
FR
dihydrocarveol
FL/FR
diosphenol
FL/FR
bitter
fennel seed oil
FR
mentha longifolia oil
FR
dextro-2,8-para-
menthadien-1-ol
FL/FR
trans-para-2,8-1-
menthadienol
FL/FR
trans-para-
menthan-2-one
FL/FR
homo
menthol
FL/FR
(-)-
menthone
FL/FR
menthoxypropane diol
FL/FR
homo
menthyl acetate
FL/FR
2-
methyl cyclohexanone
FL/FR
pennyroyal oil
FL/FR
peppermint oil CO2 extract
FL/FR
peppermint oil idaho
FL/FR
peppermint oil terpeneless
FL/FR
beta-
phellandrene
FL/FR
piperitenone
FL/FR
laevo-
piperitone
FL/FR
iso
propyl tiglate
FL/FR
(-)-iso
pulegol
FL/FR
(R)-(+)-
pulegone
FR
iso
pulegone
FL/FR
iso
pulegyl formate
FL/FR
spearmint absolute
FL/FR
spearmint oil america
FL/FR
spearmint oil terpeneless
FL/FR
tetrahydrocarvone
FL/FR
wintergreen oil
FL/FR
WS-23
FL/FR
spicy
N,N-
diethyl octanamide
FR
laevo-
verbenone
FL/FR
sulfurous
buchu mercaptan
FL/FR
thujonic
armoise oil
FR
tropical
beta-
cyclocitral
FL/FR
woody
para-tert-
butyl cyclohexanone
FR
For Flavor
No flavor group found for these
laevo-
carveol
FL/FR
carvone
FL/FR
carvyl propionate
FL/FR
cyclopentanone
FL/FR
2-
cyclopentyl cyclopentanone
FL/FR
2',4'-
dimethyl acetophenone
FL/FR
diosphenol
FL/FR
lilac lactone
FL/FR
limonen-10-yl acetate
FL
dextro-2,8-para-
menthadien-1-ol
FL/FR
cis+trans-para-1(7)8-
menthadien-2-yl acetate
FL
trans-para-2,8-1-
menthadienol
FL/FR
para-
menthane-3,8-diol
FL/FR
3-laevo-
menthoxy-2-methyl propane-1,2-diol
FL
menthoxypropane diol
FL/FR
menthyl acetate racemic
FL/FR
laevo-mono
menthyl glutarate
FL/FR
laevo-
menthyl methyl ether
FL/FR
menthyl propylene glycol carbonate
FL
2-
methyl cyclohexanone
FL/FR
beta-
phellandrene
FL/FR
(Z,Z)-
photocitral A
FL
D-(+)-alpha-
pinene
FL/FR
pinocarvone
FL/FR
piperitenone
FL/FR
piperitenone oxide
FL
iso
pulegone
FL/FR
iso
pulegyl formate
FL/FR
laevo-
verbenone
FL/FR
viridiflorol
FL/FR
thujyl alcohol
FL/FR
aldehydic
aldehydic
iso
butyraldehyde
FL/FR
camphoreous
camphor tree bark oil
FL/FR
coffee
2-iso
propyl pyrazine
FL
cooling
1,4-
cineole
FL/FR
dextro,laevo-
menthol
FL/FR
laevo-
menthol
FL/FR
menthyl acetate
FL/FR
homo
menthyl acetate
FL/FR
sabinene hydrate
FL/FR
WS-5
FL
floral
dihydrocarvyl acetate
FL/FR
geranium oil china
FL/FR
ylang ylang flower oil CO2 extract
FL/FR
ylang ylang flower oil I
FL/FR
ylang ylang flower oil II
FL/FR
ylang ylang flower oil III
FL/FR
green
cyclohexyl ethyl acetate
FL/FR
dihydrocarveol
FL/FR
geranium absolute
FL/FR
ocimene quintoxide
FL/FR
iso
propyl tiglate
FL/FR
herbal
2-
acetoxy-1,8-cineole
FL
barosma betulina leaf oil
FL/FR
hyssop oil
FL/FR
rosemary absolute
FL/FR
rosemary oil morocco
FL/FR
licorice
sweet
basil oleoresin
FL/FR
estragole
FL/FR
meaty
2-
methyl 3-(methyl thio) furan
FL
medicinal
dextro-
camphor
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil terpeneless
FL/FR
dextro-neo
menthol
FL/FR
(±)-
menthol
FL/FR
peppermint cyclohexanone
FL/FR
minty
agathosma crenulata leaf oil
FL/FR
laevo-
carvone
FL/FR
trans-para-
menthan-2-one
FL/FR
homo
menthol
FL/FR
(-)-
menthone
FL/FR
(±)-iso
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
myrtenol
FL/FR
pennyroyal oil
FL/FR
peppermint oil CO2 extract
FL/FR
peppermint oil idaho
FL/FR
peppermint oil terpeneless
FL/FR
dextro-
piperitone
FL/FR
laevo-
piperitone
FL/FR
piperitone
FL/FR
(-)-iso
pulegol
FL/FR
spearmint absolute
FL/FR
spearmint oil america
FL/FR
spearmint oil terpeneless
FL/FR
tetrahydrocarvone
FL/FR
thiogeraniol
FL/FR
wintergreen oil
FL/FR
WS-23
FL/FR
musty
3-
octanol
FL/FR
spicy
perillaldehyde
FL/FR
sulfurous
buchu mercaptan
FL/FR
tropical
beta-
cyclocitral
FL/FR
woody
dehydroxylinalool oxide
FL/FR
 
Potential Uses:
 fruit
FLmint
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 butanoic acid, 4-(dimethylamino)-4-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(+/-)-N,N-dimethyl menthyl succinamide
(1R,2S,5R)-N,N-dimethyl menthyl succinamide
N,N-dimethyl menthyl succinamide
N,N-dimethyl N'-(3-menthyl) succinamide
4-(dimethylamino-4-oxo-butanioc acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
4-(dimethylamino)-4-oxo-butanoic acid [1R-(1a,2b,5a)]-5-methyl-2-(1-methylethyl)cyclohexyl ester
N,N-dimethylmenthylsuccinamide
[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl] 4-(dimethylamino)-4-oxo-butanoate
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-(dimethylamino)-4-oxobutanoate
 
 
Notes:
Used as a food additive [EAFUS]
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy