| Name: | 2-methyl-3-[(1R,2S,5S)-5-methyl-2-propan-2-ylcyclohexyl]oxypropane-1,2-diol |
| CAS Number: | 195863-84-4 |  3D/inchi
|
| Other(deleted CASRN): | 1448241-37-9 |
| FDA UNII: | 649M1Y2P72 |
| XlogP3-AA: | 2.40 (est) |
| Molecular Weight: | 244.37476000 |
| Formula: | C14 H28 O3 |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) |
| EFSA/JECFA Comments: |
| CASrn in Register refers to the (1R, 2S, 5S) isomer. Register name to be changed to (1R,2S,5S)-3-Menthoxy-2-methylpropane-1,2-diol. |
Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 99.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.97800 to 0.98400 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 8.138 to 8.188
|
| Refractive Index: | 1.46800 to 1.47400 @ 20.00 °C.
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| Boiling Point: | 124.00 °C. @ 0.40 mm Hg
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| Boiling Point: | 368.00 to 370.00 °C. @ 760.00 mm Hg
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| Acid Value: | 1.00 max. KOH/g
|
| Flash Point: | 353.00 °F. TCC ( 178.33 °C. )
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| logP (o/w): | 2.975 (est) |
| Soluble in: |
| | alcohol | | | water, slightly | | | water, 81.61 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Type: minty |
| cooling minty |
| Odor Description:at 100.00 %. cool minty |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for 3-laevo-menthoxy-2-methyl propane-1,2-diol usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 61.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 500.00 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 18 |
| Click here to view publication 18 |
| | average usual ppm | average maximum ppm |
| baked goods: | 100.00000 | 500.00000 |
| beverages(nonalcoholic): | 300.00000 | 500.00000 |
| beverages(alcoholic): | 300.00000 | 500.00000 |
| breakfast cereal: | 100.00000 | 500.00000 |
| cheese: | - | - |
| chewing gum: | 3000.00000 | 4000.00000 |
| condiments / relishes: | 25.00000 | 100.00000 |
| confectionery froastings: | 100.00000 | 500.00000 |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 100.00000 | 500.00000 |
| fruit ices: | 15.00000 | 50.00000 |
| gelatins / puddings: | 500.00000 | 1000.00000 |
| granulated sugar: | - | - |
| gravies: | 50.00000 | 200.00000 |
| hard candy: | 250.00000 | 500.00000 |
| imitation dairy: | 100.00000 | 500.00000 |
| instant coffee / tea: | 25.00000 | 100.00000 |
| jams / jellies: | 50.00000 | 250.00000 |
| meat products: | 10.00000 | 25.00000 |
| milk products: | 20.00000 | 50.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | 50.00000 | 150.00000 |
| processed vegetables: | 25.00000 | 100.00000 |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | 20.00000 | 100.00000 |
| soft candy: | 150.00000 | 500.00000 |
| soups: | 25.00000 | 100.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | 25.00000 | 100.00000 |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
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Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87.
View page or View pdf
|
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):195863-84-4 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :16734862 |
| National Institute of Allergy and Infectious Diseases:Data |
| 2-methyl-3-[(1R,2S,5S)-5-methyl-2-propan-2-ylcyclohexyl]oxypropane-1,2-diol |
| Chemidplus:0195863844 |
References:
| | 2-methyl-3-[(1R,2S,5S)-5-methyl-2-propan-2-ylcyclohexyl]oxypropane-1,2-diol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 16734862 |
| Pubchem (sid): | 135352621 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3-L- | menthoxy-2-methyl propan-1,2-diol | | 3-laevo- | menthoxy-2-methyl propan-1,2-diol | | 3-L- | menthoxy-2-methyl propane-1,2-diol | | (1R, 2S, 5S)-3- | menthoxy-2-methylpropane-1,2-diol | | 3-(L- | menthoxy)-2-methyl propane-1,2-diol | | 3-(laevo- | menthoxy)-2-methyl propane-1,2-diol | | 3-(L- | menthoxy)-2-methylpropane-1,2-diol | | | menthoxymethyl propane diol | | | menthoxymethylpropanediol | | L-2- | methyl-3-(5-methyl-2-(1-methyl ethyl) cyclohexyl)oxy-1,2-propane diol | | laevo-2- | methyl-3-(5-methyl-2-(1-methyl ethyl) cyclohexyl)oxy-1,2-propane diol | | 2- | methyl-3-[(1R,2S,5S)-5-methyl-2-propan-2-ylcyclohexyl]oxypropane-1,2-diol | | (L)-2- | methyl-3-[5-methyl-2-(1-methylethyl)cyclohexyl]oxy-1,2-propanediol | | 1,2- | propanediol, 2-methyl-3-[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]- |
Articles:
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