EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

butyroin
5-hydroxy-4-octanone

Supplier Sponsors

Name:5-hydroxyoctan-4-one
CAS Number: 496-77-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-830-4
FDA UNII:WG070EDJ4X
Nikkaji Web:J6.098D
MDL:MFCD00021928
CoE Number:2045
XlogP3-AA:1.40 (est)
Molecular Weight:144.21392000
Formula:C8 H16 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
JECFA evaluated 5-hydroxy-4-octanone (CASrn as in Register). CASrn in Register refers to the racemate.
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:416 5-hydroxy-4-octanone
FLAVIS Number:07.065 (Old)
DG SANTE Food Flavourings:07.065 5-hydroxyoctan-4-one
FEMA Number:2587 5-hydroxy-4-octanone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):496-77-5 ; 5-HYDROXY-4-OCTANONE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
 
Physical Properties:
Appearance:yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.92000 to 0.92300 @ 20.00 °C.
Pounds per Gallon - (est).: 7.664 to 7.689
Specific Gravity:0.90700 to 0.92300 @ 20.00 °C.
Pounds per Gallon - est.: 7.556 to 7.689
Refractive Index:1.43100 to 1.43300 @ 20.00 °C.
Refractive Index:1.42600 to 1.43200 @ 20.00 °C.
Boiling Point: 80.00 to 82.00 °C. @ 10.00 mm Hg
Boiling Point: 182.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.172000 mmHg @ 25.00 °C. (est)
Flash Point: 175.00 °F. TCC ( 79.44 °C. )
logP (o/w): 1.739 (est)
Soluble in:
 alcohol
 water, very slightly
 water, 1.119e+004 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: buttery
Odor Strength:high ,
recommend smelling in a 1.00 % solution or less
sweet pungent buttery nutty
Odor Description:at 1.00 % in dipropylene glycol. sweet pungent buttery nut
Flavor Type: buttery
buttery
Taste Description: buttery
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
5-Hydroxy-4-octanone
Frinton Laboratories
For experimental / research use only.
5-Hydroxy-4-octanone
Penta International
5-HYDROXY-4-OCTANONE, Kosher
Soda Aromatic
Butyroin
Synerzine
5-Hydroxy-4-octanone
TCI AMERICA
For experimental / research use only.
Butyroin >96.0%(GC)
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for butyroin usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -7.80000
beverages(nonalcoholic): 0.500005.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 1.0000020.00000
fruit ices: 1.0000020.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -10.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 11 (FGE.11): Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 11, Revision 1 (FGE.11Rev1) - Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

EPI System: View
Env. Mutagen Info. Center:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :219794
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
5-hydroxyoctan-4-one
Chemidplus:0000496775
 
References:
 5-hydroxyoctan-4-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:496-77-5
Pubchem (cid):219794
Pubchem (sid):135296180
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FooDB:FDB008108
Export Tariff Code:2914.40.9000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
butter starter distillates
FL/FR
sulfuryl octanoate
FL/FR
sulfuryl butyrate
FL/FR
sulfuryl decanoate
FL/FR
sulfuryl hexanoate
FL/FR
sulfuryl isobutyrate
FL/FR
sulfuryl propionate
FL/FR
valeraldehyde dibutyl acetal
FL/FR
valeraldehyde propylene glycol acetal
FL/FR
acidic
acidic
iso
butyric acid
FL/FR
2-
methyl butyric acid
FL/FR
aldehydic
acetyl nonyryl
FL/FR
balsamic
cinnamyl benzoate
FL/FR
propyl benzoate
FL/FR
bready
coffee furanone
FL/FR
buttery
acetoin
FL/FR
acetoin dimer
FL/FR
acetoin propylene glycol acetal
FL/FR
acetyl butyryl
FL/FR
acetyl isobutyryl
FL/FR
acetyl propionyl
FL/FR
butter oil CO2 extract
FL/FR
butyl butyryl lactate
FL/FR
iso
butyl lactate
FL/FR
butyl octanoate
FL/FR
2,3-
heptane dione
FL/FR
3,4-
hexane dione
FL/FR
camphoreous
bornyl isobutyrate
FL/FR
caramellic
alpha,alpha-
dimethyl anisyl acetone
FL/FR
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
cheesy
butyric acid
FL/FR
2-
methyl valeric acid
FL/FR
chocolate
chocolate pyrazine A
FL/FR
2,5-
dimethyl pyrazine
FL/FR
2-
methoxypyrazine
FL/FR
2-
methyl butyraldehyde
FL/FR
coconut
alpha-
angelica lactone
FL/FR
delta-
decalactone
FL/FR
gamma-
heptalactone
FL/FR
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
delta-
undecalactone
FL/FR
corn chip
popcorn pyrimidine
FL/FR
coumarinic
coumane
FL/FR
epsilon-
decalactone
FL/FR
creamy
waxy lactone
FL/FR
earthy
2-
ethyl-3-methoxypyrazine
FL/FR
fatty
butter esters
FL/FR
butyl undecylenate
FL/FR
coconut absolute
FL/FR
fermented
butyl laevo-lactate
FL/FR
valeraldehyde
FL/FR
floral
benzyl lactate
FL/FR
para-
cresyl laurate
FL/FR
jasmin pyranone
FL/FR
linalyl butyrate
FL/FR
fruity
acetoin acetate
FL/FR
allyl 2-ethyl butyrate
FL/FR
iso
amyl nonanoate
FL/FR
gamma-
decalactone
FL/FR
ethyl lactate
FL/FR
methyl valerate
FL/FR
3-
methyl-2-butenal
FL/FR
2-
nonanone
FL/FR
prenyl isobutyrate
FL/FR
sorbyl butyrate
FL/FR
tropical thiazole
FL/FR
green
(Z)-4-
heptenal
FL/FR
2-
heptyl furan
FL/FR
(Z)-3-
hexen-1-yl butyrate
FL/FR
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
(E,Z)-2,6-
nonadienal
FL/FR
tiglaldehyde
FL/FR
mushroom
1-
octen-3-yl butyrate
FL/FR
musty
2-
acetyl pyrrole
FL/FR
3-
acetyl-2,5-dimethyl furan
FL/FR
hazelnut pyrazine
FL/FR
menthofuran
FL/FR
naphthyl
ortho-
methyl anisole
FL/FR
para-
methyl anisole
FL/FR
nutty
3-
acetyl pyridine
FL/FR
2-
acetyl-3-ethyl pyrazine
FL/FR
2-
acetyl-3-methyl pyrazine
FL/FR
2-
acetyl-3,5-dimethyl pyrazine
FL/FR
2-
acetyl-5-methyl furan
FL/FR
3,5-
cocoa pyrazine
FL/FR
3,6-
cocoa pyrazine
FL/FR
2,3-
dimethyl pyrazine
FL/FR
4,5-
dimethyl-2-ethyl-3-thiazoline
FL/FR
2-
ethyl pyrazine
FL/FR
2-
ethyl-4-methyl thiazole
FL/FR
filbert heptenone
FL/FR
filbert pyrazine
FL/FR
2,6-
lutidine
FL/FR
2-
methyl pyrazine
FL/FR
5-
methyl quinoxaline
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
2-
methyl-3-(methyl thio) pyrazine
FL/FR
2-
methyl-3-ethoxypyrazine
FL/FR
2-
methyl-3-propyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
nutty quinoxaline
FL/FR
shoyu pyrazine
FL/FR
2,3,5,6-
tetramethyl pyrazine
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
vinyl sulfurol
FL/FR
oily
butter acids
FL/FR
popcorn
2-
acetyl pyrazine
FL/FR
2-
acetyl thiazole
FL/FR
soapy
ethyl undecanoate
FL/FR
sulfurous
benzothiazole
FL/FR
furfuryl thioacetate
FL/FR
tonka
whiskey lactone
FL/FR
tropical
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
waxy
2-
methyl heptanoic acid
FL/FR
delta-
tetradecalactone
FL/FR
woody
sandalwood oil
FL/FR
For Flavor
No flavor group found for these
acetyl acetaldehyde dimethyl acetal
FL
benzyl lactate
FL/FR
bornyl isobutyrate
FL/FR
butter nut rum flavor
FL
butyl octanoate
FL/FR
butyramide
FL
chocolate pyrazine A
FL/FR
chocolate pyrazine B
FL
cinnamyl benzoate
FL/FR
coumane
FL/FR
cyclohexyl methyl pyrazine
FL
6-
decenoic acid
FL
2,5-
diethyl thiazole
FL
2,5-
diethyl-4-methyl thiazole
FL
6,7-
dihydro-2,3-dimethyl-5H-cyclopentapyrazine
FL
alpha,alpha-
dimethyl anisyl acetone
FL/FR
dimethyl dihydrocyclopentapyrazine
FL
2,5-
dimethyl thiazole
FL
ethyl 2-hydroxy-2-methyl butyrate
FL/FR
2-
ethyl-3-methoxypyrazine
FL/FR
(Z+E)-5-
ethyl-4-methyl-2-(2-butyl) thiazoline
FL
(Z+E)-5-
ethyl-4-methyl-2-(2-methyl propyl) thiazoline
FL
3-(2-
furyl) acrolein
FL
(E,E)-2,4-
heptadien-1-ol
FL
2-
hexyl-5 or 6-keto-1,4-dioxane
FL
2-
methoxypyrazine
FL/FR
methyl 2-(methyl thio) acetate
FL
3-(
methyl thio) hexanal
FL
2-
methyl-3-(methyl thio) pyrazine
FL/FR
2-
methyl-3-ethoxypyrazine
FL/FR
peanut dithiazine
FL
prenyl isobutyrate
FL/FR
2-
propyl pyridine
FL
para-
salicylic acid
FL
sodium 4-methyl-2-oxovalerate
FL
sulfuryl butyrate
FL/FR
sulfuryl decanoate
FL/FR
sulfuryl hexanoate
FL/FR
sulfuryl isobutyrate
FL/FR
valeraldehyde propylene glycol acetal
FL/FR
5-
acetyl-2,3-dihydro-1,4-thiazine
FL
sulfuryl formate
FL
sulfuryl octanoate
FL/FR
sulfuryl propionate
FL/FR
valeraldehyde dibutyl acetal
FL/FR
acidic
acidic
iso
butyric acid
FL/FR
aldehydic
acetyl nonyryl
FL/FR
alliaceous
2-
methyl thioacetaldehyde
FL
3-
tetrahydrothiophenone
FL
tropical thiazole
FL/FR
bitter
glyceryl tributyrate
FL
bready
2-
propionyl thiazole
FL
burnt
2-
methyl quinoxaline
FL
buttery
acetoin propylene glycol acetal
FL/FR
bovolide
FL
butter cream frosting flavor
FL
butter enhancers
FL
butter flavor
FL
creamy
butter flavor
FL
sweet
butter flavor
FL
butter maple flavor
FL
butter nut vanilla flavor
FL
butter oil CO2 extract
FL/FR
butter pecan flavor
FL
butter praline flavor
FL
butter starter distillates
FL/FR
butter toffee flavor
FL
butter vanilla nut flavor
FL
iso
butyl lactate
FL/FR
butyl laevo-lactate
FL/FR
diacetyl
FL
ghee flavor
FL
2,3-
heptane dione
FL/FR
3,4-
hexane dione
FL/FR
2-
methyl valeric acid
FL/FR
(E)-2-
pentenoic acid
FL
camphoreous
ortho-
methyl anisole
FL/FR
caramellic
butter rum toffee flavor
FL
3-
methyl butyl 2-furyl butyrate
FL
cheesy
2-
nonanone
FL/FR
chocolate
chocolate butter cream flavor
FL
citrus
butter lemon orange flavor
FL
coconut
delta-
decalactone
FL/FR
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
coffee
difurfuryl ether
FL
2-
ethyl-4-methyl thiazole
FL/FR
2-iso
propyl pyrazine
FL
corn chip
2-
acetyl thiazole
FL/FR
2-
acetyl-2-thiazoline
FL
popcorn pyrimidine
FL/FR
creamy
acetoin
FL/FR
acetoin butyrate
FL
acetyl butyryl
FL/FR
acetyl ethyl carbinol
FL
acetyl isobutyryl
FL/FR
alpha-
angelica lactone
FL/FR
butter esters
FL/FR
butter fat enzyme modified with added butyric acid
FL
butyl butyryl lactate
FL/FR
5,5-
dibutyl dihydrofuran-2(3H)-one
FL
divanillin
FL
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
jasmin pyranone
FL/FR
delta-
undecalactone
FL/FR
waxy lactone
FL/FR
dairy
acetoin dimer
FL/FR
earthy
2-
methyl-3-propyl pyrazine
FL/FR
ethereal
allyl 2-ethyl butyrate
FL/FR
fatty
butter acids
FL/FR
coconut absolute
FL/FR
(E,E)-2,4-
decadienal
FL
diacetyl trimer
FL
2-
heptyl furan
FL/FR
(E,E)-2,4-
nonadienal
FL
(E,E)-2,4-
undecadienal
FL
fishy
4,5-
dimethyl thiazole
FL
floral
linalyl butyrate
FL/FR
fruity
acetoin acetate
FL/FR
acetyl isovaleryl
FL
gamma-
decalactone
FL/FR
ethyl lactate
FL/FR
2,4-
hexadien-1-ol
FL
2-
methyl butyric acid
FL/FR
methyl valerate
FL/FR
3-
methyl-2-butenal
FL/FR
propyl benzoate
FL/FR
sorbyl butyrate
FL/FR
tiglaldehyde
FL/FR
fusel
2-
methyl butyraldehyde
FL/FR
green
dihydroxyacetophenone (mixed isomers)
FL
2,5-
dimethyl thiophene
FL
(Z)-4-
heptenal
FL/FR
(Z)-3-
hexen-1-yl butyrate
FL/FR
4-
methyl thiazole
FL
2-
methyl-5-isopropyl pyrazine
FL
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
(E,Z)-2,6-
nonadienal
FL/FR
2-
vinyl pyrazine
FL
lactonic
gamma-
heptalactone
FL/FR
meaty
benzothiazole
FL/FR
mushroom
1-
octen-3-yl butyrate
FL/FR
musty
2,5-
dimethyl pyrazine
FL/FR
2-
ethoxythiazole
FL
hazelnut pyrazine
FL/FR
menthofuran
FL/FR
propionaldehyde
FL
shoyu pyrazine
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
naphthyl
para-
methyl anisole
FL/FR
nutty
3-
acetyl pyridine
FL/FR
2-
acetyl pyrrole
FL/FR
3-
acetyl-2,5-dimethyl furan
FL/FR
2-
acetyl-3-ethyl pyrazine
FL/FR
2-
acetyl-3-methyl pyrazine
FL/FR
2-
acetyl-3,5-dimethyl pyrazine
FL/FR
2-
acetyl-5-methyl furan
FL/FR
butter pecan cake flavor
FL
3,5-
cocoa pyrazine
FL/FR
3,6-
cocoa pyrazine
FL/FR
coffee furanone
FL/FR
3,5-
diethyl-2-methyl pyrazine
FL
2,5-
diethyl-3-methyl pyrazine
FL
2,3-
dimethyl pyrazine
FL/FR
4,5-
dimethyl-2-ethyl-3-thiazoline
FL/FR
2,4-
dimethyl-5-vinyl thiazole
FL
2-
ethyl pyrazine
FL/FR
1-
ethyl-2-acetyl pyrrole
FL
filbert heptenone
FL/FR
filbert pyrazine
FL/FR
european
hazelnut oleoresin
FL
2,6-
lutidine
FL/FR
2-
methyl pyrazine
FL/FR
5-
methyl quinoxaline
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
nutty quinoxaline
FL/FR
nutty thiazole
FL
peanut oxazole
FL
2,3,5,6-
tetramethyl pyrazine
FL/FR
vinyl sulfurol
FL/FR
popcorn
2-
propionyl-2-thiazoline
FL
roasted
2-
acetyl pyrazine
FL/FR
furfuryl thioacetate
FL/FR
sour
butyric acid
FL/FR
spicy
spiced
butter rum flavor
FL
cinnamon butter pecan flavor
FL
cinnamon nut butter rum flavor
FL
sweet
honey distillates
FL
vanilla butter nut flavor
FL
toasted
acetyl propionyl
FL/FR
waxy
butyl undecylenate
FL/FR
para-
cresyl laurate
FL/FR
epsilon-
decalactone
FL/FR
ethyl undecanoate
FL/FR
2-
methyl heptanoic acid
FL/FR
delta-
tetradecalactone
FL/FR
winey
iso
amyl nonanoate
FL/FR
5-
ethyl-2-methyl pyridine
FL
valeraldehyde
FL/FR
woody
sandalwood oil
FL/FR
whiskey lactone
FL/FR
 
Potential Uses:
FLbutter
FLchocolate
FLnut
FLpizza
FLpopcorn
 
Occurrence (nature, food, other):note
 cocoa
Search Trop Picture
 coconut fruit
Search Trop Picture
 tea leaf
Search Trop Picture
 
Synonyms:
5-hydroxy-4-octanone
5-hydroxyoctan-4-one
 octan-4-ol-5-one
5-octanol-4-one
4-octanone, 5-hydroxy-
 
 
Notes:
None found
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