2-acetyl-3,5-dimethyl pyrazine
Constit. of wood smoke and coffee aroma. Component of *FEMA 3327*
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
      Mr. Guo86-10-68418739
      10553 2-Acetyl-3,5(or 6)-dimethylpyrazine
  • Endeavour Specialty Chemicals
    • Endeavour Specialty Chemicals Ltd
      Expertise in Small to Medium Scale Chemical Manufacturing
      Endeavour Speciality Chemicals offers high-impact aroma chemicals, all produced at the highest standards of quality.
      Endeavour Speciality Chemical has 25 years' experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavour's products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site.
      Email: Info
      Email: Sales
      Voice: +44 (0)1327 310 079
      Fax: +44 (0)1327 310 701
      Speciality Chemical Product Groups
      PZ0200 2-Acetyl-3,5-dimethylpyrazine 99% F&F
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. We warmly welcome your inquiries, come witness our solemn commitment for yourself.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      H0038 2-ACETYL-3(5/6)-DIMETHYL PYRAZINE, Kosher
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      01-07600 2-ACETYL-3,5,6-DIMETHYL PYRAZINE, Kosher
  • Robinson Brothers
  • Sigma-Aldrich
    • Sigma-Aldrich
      Complete Supply Chain
      The perfect blend of products and services that bring your creativity to life.
      Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
      Email: Information
      US Email: Sales
      US Voice: 800-244-1173
      US Fax: 800-368-4661
      Certified Food Grade Products
      W332700 2-Acetyl-3,5(6)-dimethylpyrazine, mixture of isomers, ≥98%, FG
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
      Fax: 0512-57570299
      H0038 2-Acetyl-3(5/6)-dimethyl Pyrazine
  • Treatt
    • Treatt PLC
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
      2-Acetyl-3,5 (6)-Dimethyl- Halal, Kosher
Synonyms   Articles   Notes   Search
1-(3,5-dimethylpyrazin-2-yl)ethanone (Click)
CAS Number: 54300-08-2Picture of molecule
ECHA EINECS - REACH Pre-Reg: 259-076-0
Nikkaji Web: J266.851C
MDL: MFCD00055023
CoE Number: 11294
XlogP3-AA: 0.60 (est)
Molecular Weight: 150.18090000
Formula: C8 H10 N2 O
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: Mixture of positional isomers (2-Acetyl-3,5/6-dimethyl), 3,5-dimethyl (65-70 %) and 3,6-dimethyl (25-30 %) isomers (sum 95 %) (EFFA, 2010a). The JECFA evaluated 2-acetyl-3,(5 or 6)-dimethylpyrazine (mixture of two substancs with individual CASrn for each substance). Register CASrn to be changed/deleted.
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
JECFA Food Flavoring: 786  2-acetyl-3,5-dimethylpyrazine
Flavis Number: 14.055 (Old)
DG SANTE Food Flavourings: 14.055  2-acetyl-3,5-dimethylpyrazine
FEMA Number: 3327  2-acetyl-3,5-dimethylpyrazine
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: yellow semi-solid (est)
Assay: 97.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.07000 to 1.07500 @  25.00 °C.
Pounds per Gallon - (est).: 8.903 to  8.945
Refractive Index: 1.51000 to 1.52000 @  20.00 °C.
Boiling Point: 70.00 °C. @ 7.00 mm Hg
Vapor Pressure: 3.000000 mm/Hg @ 20.00 °C.
Flash Point: 195.00 °F. TCC ( 90.56 °C. )
logP (o/w): -0.139 (est)
Soluble in:
 water, 1.855e+004 mg/L @ 25 °C (est)
Insoluble in:
Similar Items: note
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: nutty
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 nutty  hazelnut roasted hazelnut  
Odor Description:
at 0.10 % in propylene glycol. 
nutty roasted hazelnut
 nutty  hazelnut roasted hazelnut  
Taste Description:
nutty roasted hazelnut
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Beijing Lys Chemicals
2-Acetyl-3,5(or 6)-dimethylpyrazine
For experimental / research use only.
Endeavour Specialty Chemicals
2-Acetyl-3,5-dimethylpyrazine 99% F&F
Speciality Chemical Product Groups
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-Acetyl-3,5(or6)-dimethyl pyrazine, Kosherk
M&U International
Penta International
Reincke & Fichtner
2-Acetyl-3,5(and 6)-dimethylpyrazine
Robinson Brothers
2-Acetyl-3,5-dimethylpyrazine F&F
2-Acetyl-3,5(6)-dimethylpyrazine, mixture of isomers, ≥98%, FG
Certified Food Grade Products
Sunaux International
2-Acetyl-3(5/6)-dimethyl Pyrazine
Tengzhou Jitian Aroma Chemiclal
2-Acetyl-3(5/6)-dimethyl pyrazine
2-Acetyl-3,5 (6)-Dimethyl-
Halal, Kosher
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for 2-acetyl-3,5-dimethyl pyrazine usage levels up to:
  0.1000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.97 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 1.00 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 6
Click here to view publication 6
 average usual ppmaverage maximum ppm
baked goods: -5.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: -5.00000
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.00000
fruit ices: -1.00000
gelatins / puddings: -1.00000
granulated sugar: --
gravies: -5.00000
hard candy: -5.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: -1.00000
meat products: -5.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -5.00000
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
View page or View pdf
EPI System: View
EPA Substance Registry Services (TSCA): 54300-08-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 104721
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0054300082
Synonyms   Articles   Notes   Search   Top
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 54300-08-2
Pubchem (cid): 104721
Pubchem (sid): 135062346
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): HMDB39999
FooDB: FDB019681
Export Tariff Code: 2933.99.9700
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
For Odor
No odor group found for these
 sulfuryl octanoateFL/FR
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 sulfuryl propionateFL/FR
2,5-dimethyl pyrazineFL/FR
2-methoxy-3-methyl pyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
 nonyl isovalerateFL/FR
2-heptyl furanFL/FR
 hazelnut pyrazineFL/FR
2-acetyl-3-methyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
3,5-cocoa pyrazineFL/FR
 filbert heptenoneFL/FR
2-methyl-3-pentenoic acidFL/FR
 nutty quinoxalineFL/FR
2-acetyl pyrazineFL/FR
2-acetyl thiazoleFL/FR
 furfuryl thioacetateFL/FR
For Flavor
No flavor group found for these
2-acetyl-3-methyl pyrazineFL/FR
2-isobutyl-3,5-(and 3,6)-dimethyl pyrazineFL/FR
 dimethyl dihydrocyclopentapyrazineFL
2,5-dimethyl thiazoleFL
4,5-dimethyl-2-ethyl thiazoleFL
 methyl 2-(methyl thio) acetateFL
2-methyl-3-pentenoic acidFL/FR
 nonyl isovalerateFL/FR
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 sulfuryl formateFL
 sulfuryl octanoateFL/FR
 sulfuryl propionateFL/FR
corn chip
2-acetyl thiazoleFL/FR
2-heptyl furanFL/FR
4,5-dimethyl thiazoleFL
2,5-dimethyl pyrazineFL/FR
 hazelnut pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
3,5-cocoa pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
2,5-diethyl-3-methyl pyrazineFL
 filbert heptenoneFL/FR
european hazelnut oleoresinFL
2-methoxy-3-methyl pyrazineFL/FR
 nutty quinoxalineFL/FR
2,4,5-trimethyl thiazoleFL/FR
2-acetyl pyrazineFL/FR
 furfuryl thioacetateFL/FR
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 nut hazelnutFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
Search  Picture
Search  Picture
 tea green tea
Search  Picture
Synonyms   Articles   Notes   Search   Top
2-acetyl-3,5,6-dimethyl pyrazine
1-(3,5-dimethyl pyrazin-2-yl)ethanone
1-(3,5-dimethyl pyrazinyl)ethan-1-one
1-(3,5-dimethyl pyrazinyl)ethanone
 ethanone, 1-(3,5-dimethyl-2-pyrazinyl)-
 ethanone, 1-(3,5-dimethylpyrazinyl)-
Synonyms   Articles   Notes   Search   Top
 None found yet.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2017 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy