difurfuryl ether
2,2'-[oxybis(methylene)]bisfuran

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  BOC Sciences

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  Product(s):
  4437-22-3 Furan, 2,2'-(oxybis(methylene))bis-

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  Penta International Corporation

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  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  04-17625 DIFURFURYL ETHER

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  Taytonn ASCC Pte Ltd

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  We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
  Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
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  Product(s):
  Difurfuryl Ether

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  Qingdao Free Trade Zone United International Co Ltd

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  Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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  3018 Difurfuryl Ether

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  WholeChem, LLC

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  Product(s):
  Difurfuryl ether

Name: 2-(furan-2-ylmethoxymethyl)furan CAS Number: 4437-22-3 3D/inchi Other(deleted CASRN): 1801783-78-7 FDA UNII: 55L57OC81G Nikkaji Web: J102.641K Beilstein Number: 0156726 CoE Number: 10930 XlogP3-AA: 1.30 (est) Molecular Weight: 178.18730000 Formula: C10 H10 O3 NMR Predictor: Predict (works with chrome, Edge or firefox) Category: flavoring agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 1522 difurfuryl ether DG SANTE Food Flavourings: 13.061 difurfuryl ether FEMA Number: 3337 difurfuryl ether FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 4437-22-3 ; DIFURFURYL ETHER   Physical Properties: Appearance: colorless to yellow clear liquid (est) Assay: 97.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 1.50600 to 1.51200 @ 25.00 °C. Pounds per Gallon - (est).: 12.531 to 12.581 Refractive Index: 1.13800 to 1.14400 @ 20.00 °C. Boiling Point: 101.00 °C. @ 2.00 mm Hg Boiling Point: 88.00 to 89.00 °C. @ 1.00 mm Hg Acid Value: 1.00 max. KOH/g Vapor Pressure: 0.109000 mmHg @ 25.00 °C. (est) Flash Point: 222.00 °F. TCC ( 105.56 °C. ) logP (o/w): 1.797 (est) Soluble in:   alcohol   water, 711.3 mg/L @ 25 °C (est) Insoluble in:   water   Organoleptic Properties: Odor Type: coffee coffee nutty earthy Odor Description:at 0.10 % in propylene glycol. coffee nutty earthy Flavor Type: coffee coffee mushroom Taste Description: coffee mushroom-like Odor and/or flavor descriptions from others (if found). Taytonn ASCC Difurfuryl Ether Odor Description:Coffee, Earthy, Mushroom Taste Description:coffee   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. Furan, 2,2'-(oxybis(methylene))bis- Penta International DIFURFURYL ETHER Taytonn ASCC Difurfuryl Ether Odor: Coffee, Earthy, Mushroom United International Difurfuryl Ether WholeChem Difurfuryl ether   Safety Information: European information : Most important hazard(s): Xi - Irritant R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 210 mg/kg GASTROINTESTINAL: ULCERATION OR BLEEDING FROM DUODENUM GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 93, 1990. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavoring agents Recommendation for difurfuryl ether usage levels up to:   not for fragrance use.   Maximised Survey-derived Daily Intakes (MSDI-EU): 0.12 (μg/capita/day) Maximised Survey-derived Daily Intakes (MSDI-USA): 0.09 (μg/capita/day) Structure Class: II Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 6 Click here to view publication 6   average usual ppm average maximum ppm baked goods: - 1.00000 beverages(nonalcoholic): - - beverages(alcoholic): - - breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: - - fish products: - - frozen dairy: - - fruit ices: - - gelatins / puddings: - - granulated sugar: - - gravies: - 1.00000 hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - 1.00000 milk products: - - nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: - - soups: - 1.00000 sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf Statement on List of Representative Substances for Testing. The current Statement lays down a list of substances in sub-groups with representative substances for which additional data are required prior to their evaluation through the Procedure (Regulation (EC) No 1565/2000). View page or View pdf Scientific Opinion on Flavouring Group Evaluation 67 Revision 2 (FGE.67Rev2): Consideration of 28 furan-substituted compounds evaluated by JECFA at the 55th, 65th and 69th meetings (JECFA, 2001, 2006a, 2009b) View page or View pdf Scientific Opinion on Flavouring Group Evaluation 67, Revision 3 (FGE.67Rev3): consideration of 23 furan-substituted compounds evaluated by JECFA at the 55th, 65th, 69th and 86th meetings View page or View pdf EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):4437-22-3 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :263034 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 2-(furan-2-ylmethoxymethyl)furan Chemidplus:0004437223   References:   2-(furan-2-ylmethoxymethyl)furan NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 4437-22-3 Pubchem (cid): 263034 Pubchem (sid): 135263851   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View HMDB (The Human Metabolome Database): HMDB33248 FooDB: FDB011267 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View EFSA Update of results on the monitoring of furan levels in food: Read Report EFSA Previous report: Results on the monitoring of furan levels in food: Read Report EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report   Potential Blenders and core components note For Odor No odor group found for these sulfuryl octanoate FL/FR sulfuryl butyrate FL/FR sulfuryl decanoate FL/FR sulfuryl hexanoate FL/FR sulfuryl isobutyrate FL/FR sulfuryl propionate FL/FR alliaceous alliaceous methyl furfuryl disulfide FL/FR balsamic 2- acetyl furan FL/FR (E)- benzyl tiglate FL/FR caramellic coffee dione FL/FR cyclotene FL/FR fenugreek absolute FL/FR fenugreek oleoresin FL/FR iso propenyl pyrazine FL/FR chocolate cocoa hexenal FL/FR 2,6- dimethyl pyrazine FL/FR 2,4,5- trimethyl thiazole FL/FR cocoa 2- methyl butyraldehyde FL/FR coffee cichorium intybus root extract FL/FR cichorium intybus root solid extract FL/FR coffea arabica seed extract FL/FR roasted coffea arabica seed extract FL/FR coffea arabica seed oil FL/FR coffee absolute FL/FR arabica coffee bean butter FL/FR roasted arabica coffee bean essence FL/FR roasted coffee bean extract FL/FR roasted arabica coffee bean oil FL/FR roasted arabica coffee bean oil CO2 extract FL/FR coffee bean oil extract FL/FR coffee difuran FL/FR coffee resinoid FL/FR furfuryl mercaptan FL/FR 1- hydroxy-2-butanone FL/FR 2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR earthy benzyl tiglate FL/FR dibenzyl ether FL/FR 1- nonen-3-ol FL/FR nutty pyrazine FL/FR 3- octanol FL/FR 1- octen-3-ol FL/FR floral octyl acetate FL/FR 2- phenyl propionaldehyde dimethyl acetal FL/FR fruity tropical thiazole FL/FR green geranium thiazole FL/FR 2- heptyl furan FL/FR phenyl acetaldehyde dimethyl acetal FL/FR herbal thymyl methyl ether FL/FR medicinal 2,6- xylenol FL/FR musty 3- acetyl-2,5-dimethyl furan FL/FR hazelnut pyrazine FL/FR menthofuran FL/FR nutty 2- acetyl-3-ethyl pyrazine FL/FR 2- acetyl-3-methyl pyrazine FL/FR 3,5- cocoa pyrazine FL/FR 3,6- cocoa pyrazine FL/FR 2,3- dimethyl pyrazine FL/FR 4,5- dimethyl-2-ethyl-3-thiazoline FL/FR 2- ethyl-4-methyl thiazole FL/FR filbert heptenone FL/FR 2,6- lutidine FL/FR 5- methyl quinoxaline FL/FR 2- methyl thio-3,5 or 6-methyl pyrazine FL/FR nutty quinoxaline FL/FR 2,3,5,6- tetramethyl pyrazine FL/FR popcorn 2- acetyl pyrazine FL/FR sulfurous benzothiazole FL/FR furfuryl thioacetate FL/FR S- furfuryl thioformate FL/FR 2- methyl 5-(methyl thio) furan FL/FR O- methyl S-1-methoxyhexan-3-yl carbonothioate FL/FR vegetable 1- furfuryl pyrrole FL/FR mesityl oxide FL/FR tetrahydrofurfuryl alcohol FL/FR waxy 2- tridecanone FL/FR For Flavor No flavor group found for these benzyl tiglate FL/FR 6,7- dihydro-2,3-dimethyl-5H-cyclopentapyrazine FL dimethyl dihydrocyclopentapyrazine FL 6,7- dimethyl dihydrocyclopentapyrazine FL 2,5- dimethyl thiazole FL 2,5- dimethyl-3-thiofuroyl furan FL furfural diethyl acetal FL tris( methyl thio) methane FL 2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR 1,5- octadien-3-ol FL sulfuryl butyrate FL/FR sulfuryl decanoate FL/FR sulfuryl hexanoate FL/FR sulfuryl isobutyrate FL/FR sulfuryl formate FL sulfuryl octanoate FL/FR sulfuryl propionate FL/FR absinthe absinthe absinthe flavor FL alliaceous benzyl mercaptan FL dicyclohexyl disulfide FL tropical thiazole FL/FR balsamic (E)- benzyl tiglate FL/FR brown fenugreek oleoresin FL/FR 1- hydroxy-2-butanone FL/FR burnt furfuryl alcohol FL 1-(2- furfuryl thio) propanone FL 2- methyl quinoxaline FL iso propenyl pyrazine FL/FR 2,6- xylenol FL/FR caramellic caramel furanone FL cyclotene FL/FR fenugreek absolute FL/FR chocolate mocha cream flavor FL cocoa cocoa hexenal FL/FR coffee cappuccino flavor FL chicory flavor FL chicory root distillates FL chicory root essence FL roasted chicory root oil FL chicory tincture FL cichorium intybus root extract FL/FR cichorium intybus root solid extract FL/FR coffea arabica seed extract FL/FR roasted coffea arabica seed extract FL/FR coffea arabica seed oil FL/FR coffea canephora seed extract FL coffee absolute FL/FR arabica coffee bean butter FL/FR roasted coffee bean concentrate FL roasted robusta coffee bean essence FL roasted arabica coffee bean essence FL/FR roasted coffee bean essence FL dried roasted coffee bean extract FL roasted robusta coffee bean extract FL roasted coffee bean extract FL/FR roasted arabica coffee bean oil CO2 extract FL/FR coffee bean oil extract FL/FR coffee creme brulee flavor FL coffee difuran FL/FR coffee dione FL/FR coffee distillates FL espresso coffee distillates FL coffee enhancers FL espresso coffee essence FL espresso coffee extract FL coffee flavor FL irish coffee flavor FL dark roast coffee flavor FL espresso coffee flavor FL coffee liqueur flavor FL coffee pyrazine FL coffee resinoid FL/FR coffee royale flavor FL diisoamyl thiomalate FL 2,4- dimethyl thiazole FL 2- ethyl-4-methyl thiazole FL/FR furfuryl mercaptan FL/FR methyl furfuryl disulfide FL/FR methyl furfuryl mercaptopropionate FL 2- methyl-5-vinyl pyrazine FL 2-iso propyl pyrazine FL 2- thiophene thiol FL creamy acetyl ethyl carbinol FL dairy creme brulle coffee flavor FL earthy difurfuryl sulfide FL 1- nonen-3-ol FL/FR 1,8- octane dithiol FL 2- thienyl disulfide FL fatty 2- heptyl furan FL/FR 2- tridecanone FL/FR fishy 4,5- dimethyl thiazole FL fruity dibenzyl ether FL/FR furfuryl propionate FL 2- phenyl propionaldehyde dimethyl acetal FL/FR fusel 2- methyl butyraldehyde FL/FR green dihydroxyacetophenone (mixed isomers) FL 3,4- dimethoxystyrene FL geranium thiazole FL/FR 2- methyl-5-isopropyl pyrazine FL phenyl acetaldehyde dimethyl acetal FL/FR meaty benzothiazole FL/FR 2,6- dimethyl pyrazine FL/FR 3- mercapto-2-butanone FL 2- methyl 3-(methyl thio) furan FL mushroom 1- octen-3-ol FL/FR mustard furfuryl methyl ether FL musty 2- ethoxythiazole FL hazelnut pyrazine FL/FR menthofuran FL/FR 2- methyl 5-(methyl thio) furan FL/FR 3- octanol FL/FR thymyl methyl ether FL/FR nutty 2- acetyl furan FL/FR 3- acetyl-2,5-dimethyl furan FL/FR 2- acetyl-3-ethyl pyrazine FL/FR 2- acetyl-3-methyl pyrazine FL/FR 3,6- cocoa pyrazine FL/FR 3,5- cocoa pyrazine FL/FR 3,5(6)- cocoa pyrazine FL 2,3- dimethyl pyrazine FL/FR 4,5- dimethyl-2-ethyl-3-thiazoline FL/FR filbert heptenone FL/FR 2,6- lutidine FL/FR 5- methyl quinoxaline FL/FR 2- methyl thio-3,5 or 6-methyl pyrazine FL/FR nutty pyrazine FL/FR nutty quinoxaline FL/FR nutty thiazole FL tetrahydrofurfuryl alcohol FL/FR 2,3,5,6- tetramethyl pyrazine FL/FR 2,4,5- trimethyl thiazole FL/FR onion furfuryl isopropyl sulfide FL popcorn 2- propionyl-2-thiazoline FL potato mesityl oxide FL/FR roasted 2- acetyl pyrazine FL/FR roasted arabica coffee bean oil FL/FR ethyl 3-(furfuryl thio) propionate FL furfuryl thioacetate FL/FR O- methyl S-1-methoxyhexan-3-yl carbonothioate FL/FR spicy cinnamon hazelnut cappuccino flavor FL sulfurous butyl mercaptan FL ethyl methyl sulfide FL S- furfuryl thioformate FL/FR furfuryl thiopropionate FL 3- methyl-2-butane thiol FL 2- thienyl mercaptan FL vegetable 1- furfuryl pyrrole FL/FR waxy octyl 2-furoate FL octyl acetate FL/FR   Potential Uses: FL coffee FL nut   Occurrence (nature, food, other):note   chicory root oil @ 0.028% Data GC Search Trop Picture   coffee Search PMC Picture   Synonyms: 2,2'- difurfuryl ether 2,2'-(oxy dimethanediyl)difuran 2,2'-(oxy dimethylene) difuran 2,2'-(oxy dimethylene)difuran 2-( furan-2-ylmethoxymethyl) furan 2-( furan-2-ylmethoxymethyl)furan   furan, 2,2'-(oxydimethylene)di-   furan, 2,2'-[oxybis(methylene)]bis-   furan, 2,2prime-(oxybis(methylene))bis-   furfuryl ether 2,2'-(oxybis( methylene)) bisfuran 2,2'-(oxybis( methylene))bisfuran 2,2'-[oxybis( methylene)]bisfuran 2,2'-[oxybis( methylene)]difuran   Articles: Info:substances containing furan substitution US Patents:3,940,502 - Flavoring agent US Patents:Furfurylthioacetone

Notes: Flavouring ingredient