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2-acetyl-3-ethyl pyrazine
1-(3-ethylpyrazin-2-yl)ethanone

Sponsors

Name:1-(3-ethylpyrazin-2-yl)ethanone
CAS Number: 32974-92-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:251-316-2
FDA UNII:AQ03N14XTL
Nikkaji Web:J319.481G
MDL:MFCD00038028
CoE Number:11293
XlogP3-AA:0.60 (est)
Molecular Weight:150.18090000
Formula:C8 H10 N2 O
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:785 2-acetyl-3-ethylpyrazine
FLAVIS Number:14.049 (Old)
DG SANTE Food Flavourings:14.049 2-acetyl-3-ethylpyrazine
FEMA Number:3250 2-acetyl-3-ethylpyrazine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: 2-ACETYL-3-ETHYLPYRAZINE
 
Physical Properties:
Appearance:pale yellow to yellow clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.07700 to 1.08100 @ 25.00 °C.
Pounds per Gallon - (est).: 8.962 to 8.995
Specific Gravity:1.06800 to 1.07900 @ 25.00 °C.
Pounds per Gallon - est.: 8.887 to 8.978
Refractive Index:1.51200 to 1.51600 @ 20.00 °C.
Boiling Point: 220.00 to 221.00 °C. @ 760.00 mm Hg
Boiling Point: 54.00 to 56.00 °C. @ 1.00 mm Hg
Vapor Pressure:0.026000 mm/Hg @ 25.00 °C. (est)
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 0.026 (est)
Soluble in:
 alcohol
 water
 water, 2.072e+004 mg/L @ 25 °C (est)
Similar Items:note
2-acetyl-6-ethyl pyrazine
 
Organoleptic Properties:
Odor Type: nutty
Odor Strength:high ,
recommend smelling in a 1.00 % solution or less
earthy potato chip nutty popcorn corn
Odor Description:at 1.00 % in propylene glycol. earthy potato chip nutty popcorn corn
earthy nutty musty potato corn
Odor Description:at 2.00 %. Earthy, nutty, musty, potato and corn-like
Mosciano, Gerard P&F 23, No. 3, 55, (1998)
Flavor Type: nutty
musty nutty cocoa peanut vegetable potato beany
Taste Description: at 2.00 ppm. Musty, nutty, cocoa and peanut, with a vegetative, potato and bean nuance
Mosciano, Gerard P&F 23, No. 3, 55, (1998)
Odor and/or flavor descriptions from others (if found).
Frutarom
2-ACETYL-3-ETHYLPYRAZINE
Odor Description:Earthy, Nutty, Potato, Roast
Suggested Uses: Chocolate, Cocoa, Coffee, Meat, Nut, Potato
Treatt
2-Acetyl-3-ethylpyrazine Halal, Kosher
Odor Description:Potato chip, nutty, popcorn, hazelnut, meaty notes
Pell Wall Perfumes
Chip Pyrazine
Odor Description:Earthy, nutty, musty, potato-chip, corn
Naturally present in cocoa, chocolate as well as cooked meats, this is a more versatile material than you might expect, and an ideal component of the dank, earthy accords that have become popular recently in the more adventurous fine fragrances.
 
Cosmetic Information:
None found
 
Suppliers:
Anhui Haibei
2-Acetyl-3-ethyl Pyrazine
Odor: Earthy potato chip nutty popcorn corn
Apiscent Labs
2 ACETYL-3-ETHYLPYRAZINE
Odor: Nutty
Beijing Lys Chemicals
2-Acetyl-3-ethylpyrazine
BOC Sciences
For experimental / research use only.
2-Acetyl-3-ethylpyrazine
Endeavour Specialty Chemicals
2-Acetyl-3-ethylpyrazine 99% F&F
Speciality Chemical Product Groups
Ernesto Ventós
2-ACETYL-3-ETHYLPYRAZINE
Odor: EARTHY, NUTTY, POTATO, ROAST
FCI SAS
2-ACETYL-3-ETHYLPYRAZINE
Frutarom
2-ACETYL-3-ETHYLPYRAZINE
Odor: Earthy, Nutty, Potato, Roast
Use: Suggested Uses: Chocolate, Cocoa, Coffee, Meat, Nut, Potato
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-Acetyl-3-ethyl pyrazine, Kosherk
M&U International
2-ACETYL-3-ETHYL PYRAZINE, Kosher
Pearlchem Corporation
2-Acetyl-3-ethyl Pyrazine
Pell Wall Perfumes
Chip Pyrazine
Odor: Earthy, nutty, musty, potato-chip, corn
Use: Naturally present in cocoa, chocolate as well as cooked meats, this is a more versatile material than you might expect, and an ideal component of the dank, earthy accords that have become popular recently in the more adventurous fine fragrances.
Penta International
2-ACETYL-3-ETHYL PYRAZINE, Kosher
Reincke & Fichtner
2-Acetyl-3-ethylpyrazine
Robinson Brothers
2-Acetyl-3-ethylpyrazine F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
2-Acetyl-3-ethylpyrazine
Sigma-Aldrich
2-Acetyl-3-ethylpyrazine, 98%, FG
Odor: oily; meaty; nutty; vegetable
Certified Food Grade Products
Sunaux International
2-Acetyl-3-ethyl Pyrazine
Synerzine
2-Acetyl-3-Ethylpyrazine
Taytonn
2-Acetyl-3-ethylpyrazine
Odor: Earthy, Nutty, Potatoes, Roast
TCI AMERICA
For experimental / research use only.
2-Acetyl-3-ethylpyrazine >98.0%(GC)
Tengzhou Jitian Aroma Chemiclal
2-Acetyl-3-ethyl Pyrazine
Tengzhou Xiang Yuan Aroma Chemicals
2-Acetyl-3-ethyl Pyrazine
Treatt
2-Acetyl-3-ethylpyrazine
Halal, Kosher
Odor: Potato chip, nutty, popcorn, hazelnut, meaty notes
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for 2-acetyl-3-ethyl pyrazine usage levels up to:
  0.2000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.73 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.10 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
 average usual ppmaverage maximum ppm
baked goods: -10.00000
beverages(nonalcoholic): -10.00000
beverages(alcoholic): --
breakfast cereal: -10.00000
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -10.00000
fruit ices: -10.00000
gelatins / puddings: -10.00000
granulated sugar: --
gravies: -10.00000
hard candy: -10.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: -10.00000
meat products: -10.00000
milk products: -10.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -10.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
View page or View pdf

Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species
View page or View pdf

EPI System: View
EPA Substance Registry Services (TSCA):32974-92-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :61918
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-(3-ethylpyrazin-2-yl)ethanone
Chemidplus:0032974928
 
References:
 1-(3-ethylpyrazin-2-yl)ethanone
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:32974-92-8
Pubchem (cid):61918
Pubchem (sid):135018349
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):HMDB29410
FooDB:FDB000499
Export Tariff Code:2933.99.8090
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
balsamic
amyl phenyl acetate
FL/FR
butyl cinnamate
FL/FR
prenyl benzoate
FL/FR
caramellic
geranyl crotonate
FR
chocolate
iso
amyl phenyl acetate
FL/FR
iso
butyl phenyl acetate
FL/FR
chocolate pyrazine A
FL/FR
cocoa hexenal
FL/FR
cocoa oleoresin
FL/FR
2,5-
dimethyl pyrazine
FL/FR
2,4,5-
trimethyl thiazole
FL/FR
corn chip
popcorn pyrimidine
FL/FR
earthy
2-
ethyl-3-methoxypyrazine
FL/FR
nutty pyrazine
FL/FR
floral
alpha-
amyl cinnamyl acetate
FL/FR
amyl salicylate
FL/FR
autumn carboxylate
FR
green
2-sec-
butyl-3-methoxypyrazine
FL/FR
geranium thiazole
FL/FR
herbal
acorn acetate
FR
tricyclodecenyl isobutyrate
FR
honey
butyl phenyl acetate
FL/FR
phenyl acetic acid
FL/FR
medicinal
quinoline
CS
musty
2-
acetyl pyrrole
FL/FR
3-
acetyl-2,5-dimethyl furan
FL/FR
cocoa butenal
FL/FR
hazelnut pyrazine
FL/FR
menthofuran
FL/FR
nutty
3-
acetyl pyridine
FL/FR
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
2-
acetyl-5-methyl furan
FL/FR
3,6-
cocoa pyrazine
FL/FR
4,5-
dimethyl-2-ethyl-3-thiazoline
FL/FR
2-
ethyl pyrazine
FL/FR
filbert pyrazine
FL/FR
2-
methyl pyrazine
FL/FR
5-
methyl quinoxaline
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
nutty quinoxaline
FL/FR
2,3,5,6-
tetramethyl pyrazine
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
vinyl sulfurol
FL/FR
popcorn
2-
acetyl pyrazine
FL/FR
2-
acetyl pyridine
FL/FR
2-
acetyl thiazole
FL/FR
sulfurous
dimethyl sulfide
FL/FR
vanilla
ethyl vanillin isobutyrate
FL/FR
vanillin
FL/FR
vanillyl isobutyrate
FL/FR
vegetable
mesityl oxide
FL/FR
methional
FL/FR
waxy
2-
tridecanone
FL/FR
woody
4-
hydroxybenzaldehyde
FL/FR
For Flavor
No flavor group found for these
2-
acetyl-5-methyl pyrazine
FL
2-
acetyl-6-methyl pyrazine
FL
amyl phenyl acetate
FL/FR
butyl cinnamate
FL/FR
chocolate pyrazine A
FL/FR
chocolate pyrazine B
FL
6,7-
dimethyl dihydrocyclopentapyrazine
FL
dimethyl dihydrocyclopentapyrazine
FL
ethyl dimethyl pyrazine
FL
2-
ethyl-3-methoxypyrazine
FL/FR
green pea pyrazine
FL
2-
methoxy-3-propyl pyrazine
FL
methyl 2-(methyl thio) acetate
FL
4-(
methyl thio) butanol
FL
prenyl benzoate
FL/FR
2-
propionyl pyrrole
FL
alliaceous
alliaceous
3-
mercapto-2-pentanone
FL
2-
methyl thioacetaldehyde
FL
ammoniacal
2-
methyl piperidine
FL
aromatic
amyl salicylate
FL/FR
bitter
methyl ethoxypyrazine
FL
paullinia cupana seed extract
FL
bready
2-
propionyl thiazole
FL
chocolate
cocoa oleoresin
FL/FR
cocoa propanal
FL
cocoa
iso
butyl phenyl acetate
FL/FR
butyraldehyde
FL
cocoa hexenal
FL/FR
2-
methyl furan
FL
coffee
difurfuryl ether
FL
corn
2-
acetyl pyridine
FL/FR
2-
acetyl thiazole
FL/FR
2-
acetyl-2-thiazoline
FL
popcorn pyrimidine
FL/FR
creamy
4-
hydroxybenzaldehyde
FL/FR
earthy
alpha-
amyl cinnamyl acetate
FL/FR
fatty
2-
tridecanone
FL/FR
floral
iso
amyl phenyl acetate
FL/FR
phenyl acetic acid
FL/FR
green
cocoa butenal
FL/FR
dihydroxyacetophenone (mixed isomers)
FL
geranium thiazole
FL/FR
2-
methyl-5-isopropyl pyrazine
FL
propylene glycol acetone ketal
FL
honey
butyl phenyl acetate
FL/FR
malty
yeast thiazoline
FL
milky
dextro,laevo-3-(
methyl thio) butanone
FL
musty
2,5-
dimethyl pyrazine
FL/FR
hazelnut pyrazine
FL/FR
menthofuran
FL/FR
propionaldehyde
FL
2,3,5-
trimethyl pyrazine
FL/FR
nutty
3-
acetyl pyridine
FL/FR
2-
acetyl pyrrole
FL/FR
3-
acetyl-2,5-dimethyl furan
FL/FR
2-
acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR
2-
acetyl-5-methyl furan
FL/FR
3,6-
cocoa pyrazine
FL/FR
4,5-
dimethyl-2-ethyl-3-thiazoline
FL/FR
2-
ethyl pyrazine
FL/FR
2-
ethyl-6-methyl pyrazine
FL
filbert pyrazine
FL/FR
2-
methyl pyrazine
FL/FR
5-
methyl quinoxaline
FL/FR
2-
methyl thio-3,5 or 6-methyl pyrazine
FL/FR
nutty cyclohexenone
FL/FR
nutty pyrazine
FL/FR
nutty quinoxaline
FL/FR
nutty thiazole
FL
peanut oxazole
FL
2,3,5,6-
tetramethyl pyrazine
FL/FR
2,4,5-
trimethyl thiazole
FL/FR
vinyl sulfurol
FL/FR
potato
mesityl oxide
FL/FR
roasted
2-
acetyl pyrazine
FL/FR
sulfurous
dimethyl sulfide
FL/FR
potato butanone
FL
tomato
methional
FL/FR
vanilla
ethyl vanillin isobutyrate
FL/FR
vanillin
FL/FR
vanillyl isobutyrate
FL/FR
vegetable
2-sec-
butyl-3-methoxypyrazine
FL/FR
potato butyraldehyde
FL
winey
5-
ethyl-2-methyl pyridine
FL
 
Potential Uses:
 chocolate cocoa
FLcoffee
FLnut
FLpeanut
FLpopcorn
FLpork
FLpotato chip
 
Occurrence (nature, food, other):note
 cocoa
Search Trop Picture
 pork cooked pork
Search PMC Picture
 pork liver
Search PMC Picture
 
Synonyms:
2-acetyl-3-ethyl-1,4-diazine
2-acetyl-3-ethylpyrazine
2 acetyl-3-ethylpyrazine
2-acetyl-3-ethylpyrazine 99%
 chip pyrazine
 ethanone, 1-(3-ethyl-2-pyrazinyl)-
 ethanone, 1-(3-ethylpyrazinyl)-
1-(3-ethyl pyrazinyl)ethan-1-one
3-ethyl-2-pyrazinyl methyl ketone
3-ethyl-2-pyrazinylmethyl ketone
1-(3-ethylpyrazin-2-yl)ethanone
1-(3-ethylpyrazinyl)ethan-1-one
 

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Notes:
Flavouring ingredient
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