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cinnamomum cassia bark extract
extract obtained from the dried bark of the chinese cinnamon, cinnamomum cassia (l.), lauraceae

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Name:cinnamomum cassia blume bark extract
CAS Number: 84961-46-6
ECHA EC Number:284-635-0
Category:cosmetic, flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number:2257 cassia bark extract
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor Type: spicy
Odor Strength:medium
cassia cinnamon
Odor Description:at 100.00 %. cassia
Flavor Type: spicy
cassia cinnamon
Taste Description: cassia
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
masking agents
oral care agents
 
Suppliers:
Bio-Botanica®
Cinnamon Bark Cinnamomum Cassia Bark Extract
Bio-Botanica®
Cinnamon, FE – 5029
Carrubba
cinnamon cassia extract
Robertet
CANNELLE éCORCES CHINE
Pur & Nat
Solabia
SEBUSTOP®
Odor: characteristic
Use: Because of its high tannin, essential oils and saponin content, Sebustop® provides an ideal treatment for short-term reduction of excess sebum, cleansing and purifying the skin, revealing its radiance.
Vigon International
Cinnamon Co2 Extract
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic, flavor and fragrance agents
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -10.00000
beverages(nonalcoholic): -310.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -10.00000
fruit ices: -10.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -10.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
ClinicalTrials.gov:search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
cinnamomum cassia blume bark extract
Chemidplus:0084961466
 
References:
 cinnamomum cassia blume bark extract
Pubchem (sid):135310975
 
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:1302.19.0000
MedlinePlusSupp:View
Wikipedia:View
 
Potential Blenders and core components note
For Odor
balsamic
cinnamyl cinnamate
FL/FR
cinnamyl formate
FL/FR
linalyl cinnamate
FL/FR
peru balsam oil
FL/FR
peru balsam resinoid
FL/FR
2-
phenoxyethyl formate
FR
3-
phenyl propyl alcohol
FL/FR
citrus
citronitrile (Symrise)
FR
floral
3-
phenyl propionic acid
FL/FR
3-
phenyl propyl formate
FL/FR
fruity
para-
tolualdehyde
FL/FR
green
3-
hexenal
FL/FR
sorbyl isobutyrate
FL/FR
honey
methyl hydrocinnamate
FL/FR
phenolic
2'-
hydroxyacetophenone
FL/FR
spicy
allspice berry absolute
FL/FR
allspice leaf oil
FL/FR
allspice leaf oil terpeneless
FL/FR
allspice oil
FL/FR
allspice oleoresin
FL/FR
apple spice fragrance
FR
canella bark oil
FR
cassia bark concrete
FR
saigon
cassia bark oil
FL/FR
cassia bark oil china
FL/FR
cassia bark oil CO2 extract
FL/FR
cassia bark oil indonesia
FL/FR
cassia bark oil replacer
FL/FR
cassia bark oleoresin
FL/FR
cassia fragrance
FR
cassia leaf oil
FL/FR
cassia oil terpenes
FR
(E)-
cinnamaldehyde
FL/FR
cinnamaldehyde
FL/FR
(Z)-
cinnamaldehyde
FL/FR
cinnamaldehyde / methyl anthranilate schiff's base
FR
cinnamaldehyde diethyl acetal
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
cinnamaldehyde ethylene glycol acetal
FL/FR
cinnamaldehyde propylene glycol acetal
FL/FR
cinnamomum cassia bark absolute
FL/FR
cinnamomum cassia leaf extract
FR
cinnamomum cassia oil
FL/FR
cinnamomum cassia tincture
FL/FR
cinnamomum verum bark extract ceylon
FL/FR
cinnamomum verum water
FL/FR
cinnamomum zeylanicum bark powder
CS
cinnamomum zeylanicum leaf extract ceylon
FR
cinnamon acrolein
FL/FR
cinnamon bark oil
FL/FR
cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR
cinnamon bark oil (cinnamomum zeylanicum) sri lauka
FL/FR
cinnamon bark oil ceylon
FL/FR
cinnamon bark oil CO2 extract
FL/FR
cinnamon bark oil replacer
FR
cinnamon cookie fragrance
FR
cinnamon fragrance
FR
cinnamon fruit oil india
FR
cinnamon infusions
FL/FR
cinnamon leaf oil ceylon
FL/FR
cinnamon leaf oil replacer
FR
cinnamon oleoresin ceylon
FL/FR
cinnamon twig oil india
FL/FR
cinnamyl acetate
FL/FR
cinnamyl nitrile
FR
(E)-
cinnamyl nitrile
FR
croton eluteria bark oil
FL/FR
eugenol
FL/FR
3-(2-
furyl) acrolein
FL/FR
para-
methoxy-alpha-methyl cinnamaldehyde
FL/FR
ortho-
methoxycinnamaldehyde
FL/FR
(E)-para-
methoxycinnamaldehyde
FL/FR
para-
methoxycinnamaldehyde
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
methyl eugenol
FR
methyl heptadienone
FL/FR
alpha-
methyl-(E)-cinnamaldehyde
FL/FR
myrtenal
FL/FR
spicy acetoacetate
FL/FR
woody
cyperus root oil (cyperus scariosus)
FR
For Flavor
No flavor group found for these
2-
furfurylidene butyraldehyde
FL
3-(2-
furyl) acrolein
FL/FR
para-
methoxy-alpha-methyl cinnamaldehyde
FL/FR
(E)-para-
methoxycinnamaldehyde
FL/FR
methyl hydrocinnamate
FL/FR
3-
phenyl propionic acid
FL/FR
3-
phenyl propyl formate
FL/FR
sorbyl isobutyrate
FL/FR
balsamic
balsamic
peru balsam oil
FL/FR
peru balsam resinoid
FL/FR
cherry
para-
methoxycinnamaldehyde
FL/FR
cookie
cinnamon sugar
cookie flavor
FL
creamy
dihydrocoumarin
FL
fruity
linalyl cinnamate
FL/FR
green
3-
hexenal
FL/FR
methyl heptadienone
FL/FR
minty
myrtenal
FL/FR
(1R)-(-)-
myrtenal
FL
naphthyl
2'-
hydroxyacetophenone
FL/FR
nutty
furfural acetone
FL
spicy
allspice berry absolute
FL/FR
allspice flavor
FL
allspice leaf oil
FL/FR
allspice leaf oil terpeneless
FL/FR
allspice oil
FL/FR
allspice oleoresin
FL/FR
apple cinnamon french toast flavor
FL
benzylidene acetone
FL
blueberry cinnamon crumble flavor
FL
saigon
cassia bark oil
FL/FR
cassia bark oil china
FL/FR
cassia bark oil CO2 extract
FL/FR
cassia bark oil indonesia
FL/FR
cassia bark oil replacer
FL/FR
cassia bark oleoresin
FL/FR
cassia flavor
FL
cassia leaf oil
FL/FR
chocolate cinnamon hazelnut flavor
FL
(E)-
cinnamaldehyde
FL/FR
(Z)-
cinnamaldehyde
FL/FR
cinnamaldehyde
FL/FR
cinnamaldehyde diethyl acetal
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
cinnamaldehyde ethylene glycol acetal
FL/FR
cinnamaldehyde propylene glycol acetal
FL/FR
cinnamomum burmannii extract padang or batavia
FL
cinnamomum cassia bark absolute
FL/FR
cinnamomum cassia bark powder
FL
cinnamomum cassia oil
FL/FR
cinnamomum cassia tincture
FL/FR
saigon
cinnamomum loureirii bark extract
FL
cinnamomum verum bark extract ceylon
FL/FR
cinnamomum verum water
FL/FR
cinnamon
FL
cinnamon acrolein
FL/FR
cinnamon bark oil
FL/FR
cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR
cinnamon bark oil (cinnamomum zeylanicum) sri lauka
FL/FR
cinnamon bark oil ceylon
FL/FR
cinnamon bark oil CO2 extract
FL/FR
cinnamon butter pecan flavor
FL
toasted
cinnamon cashew flavor
FL
cinnamon flavor
FL
red hot
cinnamon flavor
FL
cinnamon hazelnut cappuccino flavor
FL
cinnamon hazelnut cream flavor
FL
cinnamon infusions
FL/FR
cinnamon leaf oil ceylon
FL/FR
cinnamon nut butter rum flavor
FL
cinnamon nut cream flavor
FL
cinnamon oleoresin ceylon
FL/FR
toasted
cinnamon pecan flavor
FL
cinnamon powder
FL
cinnamon twig oil india
FL/FR
cinnamyl acetate
FL/FR
cinnamyl cinnamate
FL/FR
cinnamyl formate
FL/FR
croton eluteria bark oil
FL/FR
eugenol
FL/FR
ortho-
methoxycinnamaldehyde
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
alpha-
methyl-(E)-cinnamaldehyde
FL/FR
3-
phenyl propyl alcohol
FL/FR
spicy acetoacetate
FL/FR
cinnamon
tea flavor
FL
para-
tolualdehyde
FL/FR
 
Potential Uses:
 baisers du printemps
 buckingham flowers
 couronne de fleurs
 fiori d'italia
 fleurs des champs
 hair conditioning
 huntsman's nosegay
 oral care agents
FRrose dog rose
FRrose white rose
FRwallflower
FRwintergreen
 yacht club
 
Occurrence (nature, food, other):note
 cassia
Search Trop Picture
 
Synonyms:
 camphorina cassia bark extract
 cannelle écorces bark extract
 cassia bark extract
 cinnamomum aromaticum bark extract
 cinnamomum longifolium bark extract
 cinnamomum medium bark extract
 cinnamomum nitidum bark extract
 cinnamon cassia bark extract
 extract obtained from the dried bark of the chinese cinnamon, cinnamomum cassia (l.), lauraceae
 laurus cassia bark extract
 persea cassia bark extract
 

Articles:

PubMed:Agrimonia pilosa Ledeb., Cinnamomum cassia Blume, and Lonicera japonica Thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats.
PubMed:Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) Can Ameliorate Cyclophosphamide-induced Ongoing Bladder Overactivity and Acidic Adenosine Triphosphate Solution-induced Hyperactivity on Rats Prestimulated Bladder.
PubMed:Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells.
PubMed:Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway.
PubMed:In Vitro Antiviral Activity of Cinnamomum cassia and Its Nanoparticles Against H7N3 Influenza A Virus.
PubMed:Cinnamomum cassia: an implication of serotonin reuptake inhibition in animal models of depression.
PubMed:Cinnamon and its Components Suppress Vascular Smooth Muscle Cell Proliferation by Up-Regulating Cyclin-Dependent Kinase Inhibitors.
PubMed:Essential Oils, Silver Nanoparticles and Propolis as Alternative Agents Against Fluconazole Resistant Candida albicans, Candida glabrata and Candida krusei Clinical Isolates.
PubMed:Anti-diabetic nephropathy compounds from Cinnamomum cassia.
PubMed:Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala.
PubMed:Cinnamomum cassia bark produced by solid-state fermentation with Phellinus baumii has the potential to alleviate atopic dermatitis-related symptoms.
PubMed:A new phenolic glycoside from the barks of Cinnamomum cassia.
PubMed:Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia.
PubMed:Traditional formula, modern application: chinese medicine formula sini tang improves early ventricular remodeling and cardiac function after myocardial infarction in rats.
PubMed:Effect of Cinnamomum cassia methanol extract and sildenafil on arginase and sexual function of young male Wistar rats.
PubMed:Evaluation of the in vitro anti-hyperglycemic effect of Cinnamomum cassia derived phenolic phytochemicals, via carbohydrate hydrolyzing enzyme inhibition.
PubMed:Interaction of gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice.
PubMed:Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer.
PubMed:Identification of compounds from the water soluble extract of Cinnamomum cassia barks and their inhibitory effects against high-glucose-induced mesangial cells.
PubMed:A novel concept for detoxification: complexation between aconitine and liquiritin in a Chinese herbal formula ('Sini Tang').
PubMed:Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling.
PubMed:Fumigant toxicity of plant essential oils against Camptomyia corticalis (Diptera: Cecidomyiidae).
PubMed:Antioxidant activity of various parts of Cinnamomum cassia extracted with different extraction methods.
PubMed:Bioactive A-type proanthocyanidins from Cinnamomum cassia.
PubMed:Differential antiproliferation effect of 2'-benzoyloxycinnamaldehyde in K-ras-transformed cells via downregulation of thiol antioxidants.
PubMed:2'-Hydroxycinnamaldehyde targets low-density lipoprotein receptor-related protein-1 to inhibit lipopolysaccharide-induced microglial activation.
PubMed:Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks.
PubMed:Platelet anti-aggregation activities of compounds from Cinnamomum cassia.
PubMed:Anti-inflammatory activities of essential oils and their constituents from different provenances of indigenous cinnamon (Cinnamomum osmophloeum) leaves.
PubMed:The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells.
PubMed:Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1.
PubMed:Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential.
PubMed:Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells.
PubMed:Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways.
PubMed:Cinnamic acid, from the bark of Cinnamomum cassia, regulates glucose transport via activation of GLUT4 on L6 myotubes in a phosphatidylinositol 3-kinase-independent manner.
PubMed:[Analysis on the chemical compositions of the volatile oil from ultramicro-powder and common grinding powder of Cinnamomum cassia].
PubMed:Quality assessment of cortex cinnamomi by HPLC chemical fingerprint, principle component analysis and cluster analysis.
PubMed:Apoptosis induction of 2'-hydroxycinnamaldehyde as a proteasome inhibitor is associated with ER stress and mitochondrial perturbation in cancer cells.
PubMed:Nematicidal Activity of Cassia and Cinnamon Oil Compounds and Related Compounds toward Bursaphelenchus xylophilus (Nematoda: Parasitaphelenchidae).
PubMed:Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells.
PubMed:Repellency of Cinnamomum cassia bark compounds and cream containing cassia oil to Aedes aegypti (Diptera: Culicidae) under laboratory and indoor conditions.
PubMed:In vitro efficacy of 75 essential oils against Aspergillus niger.
PubMed:Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat.
PubMed:Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume.
PubMed:Delayed occurrence of H-ras12V-induced hepatocellular carcinoma with long-term treatment with cinnamaldehydes.
PubMed:Effects of cassia oil on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver.
PubMed:Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and in vitro.
PubMed:Authentication and quantitative analysis on the chemical profile of cassia bark (cortex cinnamomi) by high-pressure liquid chromatography.
PubMed:Inhibitory effect of 2'-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kappa B activation in RAW 264.7 cells.
PubMed:Inhibition of Trypanosoma cruzi by plant extracts used in Chinese medicine.
PubMed:Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia.
PubMed:[Isolation of genomic DNA from Cinnamomum cassia Presl].
PubMed:Repellency of aromatic medicinal plant extracts and a steam distillate to Aedes aegypti.
PubMed:Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma.
PubMed:Antioxidant activity of Cinnamomum cassia.
PubMed:Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells.
PubMed:Measurement of plasma procyanidin B-2 and procyanidin B-3 levels after oral administration in rat.
PubMed:[Comparison studies on chemical constituents of essential oil from Ramulus Cinnamomi and Cortex Cinnamomi by GC-MS].
PubMed:Inhibitory activity of Cinnamomum cassia bark-derived component against rat lens aldose reductase.
PubMed:Suppression effect of Cinnamomum cassia bark-derived component on nitric oxide synthase.
PubMed:Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties.
PubMed:Growth-Inhibiting Effects of Cinnamomum cassia Bark-Derived Materials on Human Intestinal Bacteria.
PubMed:A survey of some Indian medicinal plants for anti-human immunodeficiency virus (HIV) activity.
PubMed:Extract prepared from the bark of Cinnamomum cassia Blume prevents glutamate-induced neuronal death in cultured cerebellar granule cells.
PubMed:Insecticidal and fumigant activities of Cinnamomum cassia bark-derived materials against Mechoris ursulus (Coleoptera: attelabidae).
PubMed:Synthesis and in vitro cytotoxicity of cinnamaldehydes to human solid tumor cells.
PubMed:Cinnamaldehyde inhibits lymphocyte proliferation and modulates T-cell differentiation.
PubMed:2'-Hydroxycinnamaldehyde from stem bark of Cinnamomum cassia.
PubMed:Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas.
PubMed:A reticuloendothelial system-activating arabinoxylan from the bark of Cinnamomum cassia.
PubMed:Antiulcerogenic compounds isolated from Chinese cinnamon.
PubMed:Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats.
PubMed:[Pharmacological studies of Cinnamomum cassia bark. Part I. Effects on the blood and cardiovascular system (author's transl)].
 
Notes:
Use with Caution and in only very small quantites.
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