EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

leerall
lyral (IFF)

Sponsors

Fragrance Demo Formulas
Name:4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
CAS Number: 31906-04-4Picture of molecule3D/inchi
Other:56493-02-8
ECHA EINECS - REACH Pre-Reg:250-863-4
FDA UNII:QUE43B9Z2Q
Nikkaji Web:J68.877K
Beilstein Number:2046455
MDL:MFCD00019423
XlogP3-AA:1.70 (est)
Molecular Weight:210.31674000
Formula:C13 H22 O2
NMR Predictor:Predict (works with chrome or firefox)
Also(can) Contains:3,4-leerall 20.00% to 34.00%
Category:fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless to pale yellow clear viscous liquid (est)
Assay: 97.00 to 100.00 sum of isomers
Food Chemicals Codex Listed: No
Specific Gravity:0.98900 to 0.99700 @ 25.00 °C.
Pounds per Gallon - (est).: 8.229 to 8.296
Refractive Index:1.48600 to 1.49300 @ 20.00 °C.
Boiling Point: 318.65 °C. @ 760.00 mm Hg (est)
Acid Value: 5.00 max. KOH/g
Vapor Pressure:0.000029 mm/Hg @ 25.00 °C. (est)
Flash Point: 200.00 °F. TCC ( 93.33 °C. )
logP (o/w): 2.080
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 water, very slightly
 water, 184.6 mg/L @ 25 °C (est)
Insoluble in:
 paraffin oil
 water
Stability:
 alcoholic fine fragrance, good
 alcoholic lotion
 antiperspirant, good
 deo stick
 detergent perborate
 fabric softener, good
 hard surface cleaner
 liquid detergent
 shampoo
 soap, good
 
Organoleptic Properties:
Odor Type: floral
Odor Strength:medium
Substantivity:400 hour(s) at 100.00 %
floral muguet cyclamen rhubarb woody
Odor Description:at 100.00 %. floral muguet cyclamen rhubarb woody
Luebke, William tgsc, (1986)
Odor sample from: International Flavors & Fragrances Inc.
Odor and/or flavor descriptions from others (if found).
IFF
Lyral®
Odor Description:Soft delicate floral, lily, cyclamen, lilac note reminiscent of hydrocycitronellal
Extraordinary tenacity and diffusivity. A powerful blending agent giving richness throughout all dryout phases of a perfume composition.
Takasago
Kovanol ≥98%
Odor Description:Sweet and floral
Used in floral fragrances, mainly muguet accords. Unique as a fine light flower tone that is extremely long lasting.
Indukern F&F
LYRAL
Odor Description:FLORAL, ALDEHYDIC, SWEET, LILAC
PerfumersWorld
Lyral
Odor Description:soft delicate floral lily cyclamen note hydroxycitronellal delicately sweet-light-floral
Blends-well-with - Resinoids Styrax
Pell Wall Perfumes
Lyral
Odor Description:Floral-muguet, aldehydic, powdery
Arctander writes very enthusiastically about this material: “Lyral was at first believed to be of fixative value only, e. g. in high-class soap perfumes, etc. But it was soon discovered that Lyral has a floral volume which, when properly ‘cultivated’ by the creative perfumer, often outperforms Hydrocitronellal and any other floral chemical or combination of chemicals, its application is therefore continuously expanding from the single floral Muguet to become the ‘must’ in cosmetic fragrances where tenacity and sweet-powdery, stable terminal notes are called for. It blends excellently with the Ionones and with the conventional resinoids (Styrax, Tolu, Peru, etc. ) and it may either accompany Hydroxycitronellal or substitute it.
IFF
Lyral® Tocopherol
Odor Description:Soft delicate floral, lily, cyclamen, lilac note reminiscent of hydrocycitronellal
Extraordinary tenacity and diffusivity. A powerful blending agent giving richness throughout all dryout phases of a perfume composition.
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
perfuming agents
 
Suppliers:
A.C.S. International
Lydoucal
Operational Capabilities
Associate Allied Chemicals
Lyral
About
Azelis UK
LYRAL
Services
Berjé
Lyral™
Happening at Berje
CG Herbals
Lyral
Odor: Lilac flower-like
Ernesto Ventós
LYRAL IFF
Odor: FLORAL, MUGUET, ALDEHYDIC, WOODY
Foreverest Resources
Lyral 98%
Odor: characteristic
Use: Lyral is a mixture of isomer, appears liquid with floral olfactive, has impression of Lily of the valley. It applied as fragrance ingredient in the formula of perfume, soaps, household cleaners and personal cares.
Global Essence
Lyral
IFF
Lyral® Tocopherol
Odor: Soft delicate floral, lily, cyclamen, lilac note reminiscent of hydrocycitronellal
Use: Extraordinary tenacity and diffusivity. A powerful blending agent giving richness throughout all dryout phases of a perfume composition.
IFF
Lyral®
Odor: Soft delicate floral, lily, cyclamen, lilac note reminiscent of hydrocycitronellal
Use: Extraordinary tenacity and diffusivity. A powerful blending agent giving richness throughout all dryout phases of a perfume composition.
Indenta Group
Lyral
Indukern F&F
LYRAL EXTRA
Odor: FLORAL, MUGUET, ALDEHYDIC, WOODY
Indukern F&F
LYRAL
Odor: FLORAL, ALDEHYDIC, SWEET, LILAC
Jiangyin Healthway
New Suzuran aldehyde
New functional food ingredients
Keva
CYCLOHEXAL
Kun Shan P&A
Lyral
Lluch Essence
LYRAL
M&U International
LYRAL
Moellhausen
KOVANOL
Odor: floreal, cyclamen, reminiscence of hydroxycitronellal
O'Laughlin Industries
KOVYRAL
OQEMA
Lanyral
PCW France
Lysinal
Steps to a fragranced product
Pell Wall Perfumes
Lyral Replacer
Odor: characteristic
Use: This blend by Pell Wall is designed to act as a general purpose replacement for Lyral. It is based on a replacer designed by an IFF perfumer, further developed by Pell Wall adding ingredients from other manufacturers. This base does not contain any ingredients that are restricted under the 48th amendment of the IFRA standards nor anything that needs to be declared on labels under the EU Cosmetics Regulations in force as at June 2016.
Pell Wall Perfumes
Lyral
Odor: Floral-muguet, aldehydic, powdery
Use: Arctander writes very enthusiastically about this material: “Lyral was at first believed to be of fixative value only, e. g. in high-class soap perfumes, etc. But it was soon discovered that Lyral has a floral volume which, when properly ‘cultivated’ by the creative perfumer, often outperforms Hydrocitronellal and any other floral chemical or combination of chemicals, its application is therefore continuously expanding from the single floral Muguet to become the ‘must’ in cosmetic fragrances where tenacity and sweet-powdery, stable terminal notes are called for. It blends excellently with the Ionones and with the conventional resinoids (Styrax, Tolu, Peru, etc. ) and it may either accompany Hydroxycitronellal or substitute it.
Penta International
4-(4-HYDROXY-4-METHYLPENTYL)-3-CYCLOHEXENE-1-CARBOXALDEHYE
PerfumersWorld
Lyral
Odor: soft delicate floral lily cyclamen note hydroxycitronellal delicately sweet-light-floral
Use: Blends-well-with - Resinoids Styrax
Perfumery Laboratory
LIRAL® IFF (LYRAL® IFF)
Odor: Soft, delicate fragrance of lily of the valley, cyclamen, lilac
Phoenix Aromas & Essential Oils
Lyral
Reincke & Fichtner
4-(4-Hydroxy-4-methyl Pentyl)-3-cyclohexene-1-carboxaldehyde
Santa Cruz Biotechnology
For experimental / research use only.
4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (mixture of isomers) ≥97%
Sigma-Aldrich
For experimental / research use only.
4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde mixture of isomers, analytical standard
Takasago
Kovanol
≥98%
Odor: Sweet and floral
Use: Used in floral fragrances, mainly muguet accords. Unique as a fine light flower tone that is extremely long lasting.
The Fragrance Museum
Taytonn
Lyral®
The Good Scents Company
leerall
Odor: floral muguet cyclamen rhubarb woody
The John D. Walsh Company
Lyral
The Lermond Company
Lyral
The Perfumers Apprentice
Lyral - Leerall
Odor: A soft delicate floral lily, cyclamen note, reminiscent of muguet
Use: Extraordinary tenacity and diffusivity. A powerful blending agent giving richness throughout all dryout phases of a perfume composition.
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
GHS Label elements, including precautionary statements
 
Pictogramexclamation-mark.jpg
 
Signal word Warning
Hazard statement(s)
H302 - Harmful if swallowed
H316 - Causes mild skin irritation
H320 - Causes eye irritation
Precautionary statement(s)
P264 - Wash skin thouroughly after handling.
P270 - Do not eat, drink or smoke when using this product.
P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 - Rinse mouth.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-rat LD50 3250 ul/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: TREMOR
National Technical Information Service. Vol. OTS0535072

Dermal Toxicity:
skin-rabbit LD50 11300 ul/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
National Technical Information Service. Vol. OTS0535072

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: fragrance agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.02 % (1)
Category 2:  0.02 %
Category 3:  0.20 %
Category 4:  0.20 %
Category 5:  0.20 %
Category 6:  0.20 % (1)
Category 7:  0.02 %
Category 8:  0.20 %
Category 9:  0.20 %
Category 10:  0.20 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for leerall flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):31906-04-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91604
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:2
4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
Chemidplus:0031906044
RTECS:GW2850000 for cas# 31906-04-4
 
References:
 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:31906-04-4
Pubchem (cid):91604
Pubchem (sid):135048904
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2912.30.0000
Typical G.C.
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
aldehydic
citrus carbaldehyde
FR
decanal (aldehyde C-10)
FL/FR
dodecanal (aldehyde C-12 lauric)
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
nonanal (aldehyde C-9)
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
amber
ambroxan
FL/FR
angelica root oil
FL/FR
cistus ladaniferus resinoid
FR
animal
para-
cresyl caprylate
FL/FR
anise
anise seed oil
FL/FR
sweet
fennel seed oil
FL/FR
balsamic
iso
amyl benzoate
FL/FR
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzophenone
FR
benzyl cinnamate
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
cinnamyl alcohol
FL/FR
clover nitrile
FR
ethyl cinnamate
FL/FR
fir balsam absolute
FR
fir needle oil siberia
FL/FR
fir tree fragrance
FR
methyl (E)-cinnamate
FL/FR
3-
phenyl propyl alcohol
FL/FR
berry
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
buttery
acetoin
FL/FR
caramellic
strawberry furanone
FL/FR
citrus
bergamot oil bergaptene reduced italy
FL/FR
dihydromyrcenol
FL/FR
grapefruit oil c.p. california
FL/FR
grapefruit pentanol
FR
alpha-
methylene citronellal
FR
blood
orange oil italy
FL/FR
sweet
orange peel oil c.p. brazil
FL/FR
tangerine oil america
FL/FR
tetrahydromyrcenol
FR
coconut
gamma-
heptalactone
FL/FR
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
gamma-
octalactone
FL/FR
fatty
decanol
FL/FR
floral
alpha-
amyl cinnamaldehyde
FL/FR
iso
amyl salicylate
FL/FR
benzyl acetate
FL/FR
benzyl alcohol
FL/FR
bois de rose oil brazil
FL/FR
4-iso
butyl cyclohexane propanal
FR
cilantro herb oil egypt
FL/FR
citronellol
FL/FR
citronellyl acetate
FL/FR
coriander seed oil
FL/FR
corps popinal
FR
cuminyl acetaldehyde
FL/FR
cyclamen aldehyde
FL/FR
cyclamen homoaldehyde
FR
cyclohexyl ethyl alcohol
FL/FR
9-
decen-1-ol
FL/FR
dihydrojasmone
FL/FR
dimethyl anthranilate
FL/FR
dimethyl benzyl carbinol
FL/FR
dimethyl benzyl carbinyl acetate
FL/FR
dimethyl benzyl carbinyl butyrate
FL/FR
2,5-
dimethyl-2-indan methanol
FR
4-
ethyl cyclohexane propanal
FR
(E,E)-
farnesol
FL/FR
floral pyranol
FR
floral specialty
FR
gardenia oxide
FR
geraniol
FL/FR
geranium oil bourbon
FL/FR
geranyl acetate
FL/FR
heliotropin
FL/FR
heliotropyl acetate
FL/FR
heliotropyl acetone
FL/FR
heliotropyl diethyl acetal
FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
ho leaf oil
FR
hyacinth ether
FR
hydroxycitronellal
FL/FR
calla
lily fragrance
FR
lily of the valley specialty
FR
lilyall
FR
lilyall / methyl anthranilate schiff's base
FR
lilyall substitute
FR
laevo-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
magnolia cyclohexanol
FR
methoxycitronellal
FR
para-
methyl acetophenone
FL/FR
4-
methyl cyclohexane propanal
FR
methyl dihydrojasmonate
FL/FR
mimosa absolute france
FL/FR
muguet butanol
FR
muguet carboxaldehyde
FR
muguet ethanol
FR
muguet octadienol
FR
nerol
FL/FR
nerolidol
FL/FR
neryl acetate
FL/FR
nonanol
FL/FR
ocean propanal
FL/FR
octahydro-4,7-methano-1H-indene-5-acetaldehyde
FR
octahydro-4,7-methano-1H-indene-5-acetaldehyde + 6-methyl-octahydro-4,7-methano-indene-5-carbaldehyd
FR
orris pyridine 25% IPM
FR
peony alcohol
FR
petitgrain oil paraguay
FL/FR
phenethyl acetate
FL/FR
phenethyl alcohol
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl isovalerate
FL/FR
phenethyl phenyl acetate
FL/FR
phenethyl propionate
FL/FR
4-
propyl cyclohexane propanal
FR
rhodinol
FL/FR
rose butanoate
FL/FR
tetrahydrolinalool
FL/FR
violet methyl carbonate
FR
ylang ylang flower oil
FL/FR
fruity
allyl amyl glycolate
FR
allyl cyclohexyl propionate
FL/FR
benzyl propionate
FL/FR
2-
cyclopentyl cyclopentanone
FL/FR
(E)-alpha-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
gamma-
decalactone
FL/FR
dimethyl benzyl carbinyl isobutyrate
FR
(R)-gamma-
dodecalactone
FL/FR
green acetate
FR
methyl anthranilate
FL/FR
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
acetaldehyde ethyl phenethyl acetal
FL/FR
diphenyl oxide
FL/FR
galbanum oil
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl benzoate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
hexyl 2-methyl butyrate
FL/FR
hexyl tiglate
FL/FR
(Z)-
leaf acetal
FL/FR
melon nonenoate
FL/FR
methyl heptine carbonate
FL/FR
methyl octine carbonate
FL/FR
(Z)-5-
octen-1-ol
FL/FR
phenyl acetaldehyde
FL/FR
phenyl acetaldehyde dimethyl acetal
FL/FR
3-
phenyl propionaldehyde
FL/FR
styralyl acetate
FL/FR
violet leaf absolute
FL/FR
hay
beeswax absolute
FL/FR
hay absolute
FR
herbal
carum carvi fruit oil
FL/FR
clary sage oil france
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
linalyl acetate
FL/FR
nopyl acetate
FR
alpha-
terpinyl acetate
FL/FR
honey
methyl phenyl acetate
FL/FR
marine
green
algae absolute
FL/FR
melon
melon heptenal
FL/FR
watermelon ketone
FR
minty
spearmint oil america
FL/FR
mossy
oakmoss absolute
FL/FR
veramoss (IFF)
FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
powdery
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
spicy
benzyl isoeugenol
FL/FR
carnation absolute
FR
cassia bark oil china
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
elettaria cardamomum seed oil
FL/FR
eugenol
FL/FR
iso
eugenyl acetate
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
methyl isoeugenol
FL/FR
nutmeg oil
FL/FR
black
pepper oil
FL/FR
pimenta acris leaf oil
FL/FR
terpenic
frankincense oil
FL/FR
juniperus communis fruit oil
FL/FR
alpha-
terpineol
FL/FR
thujonic
armoise oil
FR
tonka
gamma-
hexalactone
FL/FR
tonka bean absolute
FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decyl acetate
FL/FR
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
1-
undecanol
FL/FR
woody
amber carbinol
FR
frankincense resinoid replacer
FR
guaiacwood oil
FL/FR
gurjun balsam oil
FR
methyl cedryl ketone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
santall
FR
spruce needle oil canada
FL/FR
tobacarol (IFF)
FR
vetiver oil haiti
FL/FR
woody acetate
FR
(Z)-
woody amylene
FR
For Flavor
No flavor group found for these
green
algae absolute
FL/FR
2-
cyclopentyl cyclopentanone
FL/FR
(R)-gamma-
dodecalactone
FL/FR
(E,E)-
farnesol
FL/FR
methyl (E)-cinnamate
FL/FR
aldehydic
aldehydic
nonanal (aldehyde C-9)
FL/FR
1-
undecanol
FL/FR
animal
para-
cresyl caprylate
FL/FR
anise
anise seed oil
FL/FR
sweet
fennel seed oil
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
ethyl cinnamate
FL/FR
fir needle oil siberia
FL/FR
berry
heliotropyl acetone
FL/FR
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
brown
beeswax absolute
FL/FR
caramellic
strawberry furanone
FL/FR
cherry
heliotropin
FL/FR
citrus
bergamot oil bergaptene reduced italy
FL/FR
grapefruit oil c.p. california
FL/FR
linalool
FL/FR
laevo-
linalool
FL/FR
nerol
FL/FR
blood
orange oil italy
FL/FR
sweet
orange peel oil c.p. brazil
FL/FR
petitgrain oil paraguay
FL/FR
tangerine oil america
FL/FR
alpha-
terpineol
FL/FR
coconut
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
creamy
acetoin
FL/FR
gamma-
hexalactone
FL/FR
para-
methyl acetophenone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
fatty
(Z)-3-
hexen-1-yl benzoate
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
bois de rose oil brazil
FL/FR
citronellol
FL/FR
citronellyl acetate
FL/FR
dihydrojasmone
FL/FR
dimethyl benzyl carbinyl acetate
FL/FR
dimethyl benzyl carbinyl butyrate
FL/FR
geraniol
FL/FR
geranium oil bourbon
FL/FR
heliotropyl acetate
FL/FR
linalyl acetate
FL/FR
methyl dihydrojasmonate
FL/FR
methyl phenyl acetate
FL/FR
neryl acetate
FL/FR
ocean propanal
FL/FR
phenethyl alcohol
FL/FR
phenethyl propionate
FL/FR
rhodinol
FL/FR
tetrahydrolinalool
FL/FR
ylang ylang flower oil
FL/FR
fruity
allyl cyclohexyl propionate
FL/FR
iso
amyl benzoate
FL/FR
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
benzyl acetate
FL/FR
benzyl alcohol
FL/FR
benzyl propionate
FL/FR
(E)-alpha-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
gamma-
decalactone
FL/FR
dimethyl anthranilate
FL/FR
methyl anthranilate
FL/FR
phenethyl isovalerate
FL/FR
rose butanoate
FL/FR
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
styralyl acetate
FL/FR
green
acetaldehyde ethyl phenethyl acetal
FL/FR
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
cinnamyl alcohol
FL/FR
cuminyl acetaldehyde
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
dihydromyrcenol
FL/FR
diphenyl oxide
FL/FR
galbanum oil
FL/FR
geranyl acetate
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
hexyl 2-methyl butyrate
FL/FR
hexyl tiglate
FL/FR
(Z)-
leaf acetal
FL/FR
linalool oxide
FL/FR
melon heptenal
FL/FR
melon nonenoate
FL/FR
methyl heptine carbonate
FL/FR
methyl octine carbonate
FL/FR
nerolidol
FL/FR
oakmoss absolute
FL/FR
(Z)-5-
octen-1-ol
FL/FR
phenyl acetaldehyde dimethyl acetal
FL/FR
3-
phenyl propionaldehyde
FL/FR
violet leaf absolute
FL/FR
herbal
carum carvi fruit oil
FL/FR
cilantro herb oil egypt
FL/FR
clary sage oil france
FL/FR
coriander seed oil
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
honey
phenethyl acetate
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl phenyl acetate
FL/FR
phenyl acetaldehyde
FL/FR
lactonic
gamma-
heptalactone
FL/FR
gamma-
octalactone
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
minty
spearmint oil america
FL/FR
powdery
beta-
naphthyl ethyl ether
FL/FR
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
1-
dodecanol
FL/FR
spicy
benzyl cinnamate
FL/FR
benzyl isoeugenol
FL/FR
cassia bark oil china
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
elettaria cardamomum seed oil
FL/FR
eugenol
FL/FR
iso
eugenyl acetate
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
methyl isoeugenol
FL/FR
nutmeg oil
FL/FR
black
pepper oil
FL/FR
3-
phenyl propyl alcohol
FL/FR
pimenta acris leaf oil
FL/FR
terpenic
juniperus communis fruit oil
FL/FR
tropical
alpha-
amyl cinnamaldehyde
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decanal (aldehyde C-10)
FL/FR
decanol
FL/FR
9-
decen-1-ol
FL/FR
decyl acetate
FL/FR
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
mimosa absolute france
FL/FR
nonanol
FL/FR
woody
ambroxan
FL/FR
amyris wood oil
FL/FR
iso
bornyl acetate
FL/FR
frankincense oil
FL/FR
guaiacwood oil
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
spruce needle oil canada
FL/FR
alpha-
terpinyl acetate
FL/FR
vetiver oil haiti
FL/FR
 
Potential Uses:
FRacacia
FRagrumen aldehyde
FRaldehydic
FRalmond
 almond blossom
 alpine bouquet
FRamber
FRambergris
FRambrette oil replacer
 angel
FL/FRangelica
FRanimal
FRapple
FRapple blossom
 apple crabapple
FRapple green apple
FRapple red apple
 ash mountain ash berry
FRbalsam
FRbanana
 bark
FRbay rum
FRbayberry
FRbergamot
FRblackberry
FRblueberry
 blueberry whortleberry red whortleberry
FRbois de rose
 botanical
FRbouquet
 boxwood blossom
FRboysenberry
 bramble arctic bramble blackberry
FRbubble gum
 burberry
FRbutterscotch
FRcalamus oil replacer
FLcaramel
FRcarnation
 cassia blossom
FRcedar
FRcedar forest
FRcherry
FRcherry blossom
FRchypre
FRcitrus
FRcivet
FRclematis
 cloth clean cloths
 cloudberry bakeapple
 clove blossom
FRclover
FRcolonia
FRcostus
FRcountry meadow
FRcrabapple blossom
FRcranberry
FRcucumber
FRcuracao
FRcurrant
FRcyclamen
FRdaffodil
FRdillenia
FReglantine
FRelder berry
FRelder flower
FRfagonia
 fantasy blends
FRfern
FRfetes
 fidji
FRfig
FRfir balsam
FRfir needle oil replacer
FRfloral
 florida breeze
 foliage
FRforest
FRfrangipani plumeria
FRfreesia
FRfresh outdoors
FRgalbanum
FRgardenia
FRgenet
FRgeranium
FRginger
FRginger white ginger
FL/FRgingergrass
FRgooseberry
FRgrape
FRgrapefruit
FRgreenhouse
FL/FRguaiacwood
FRguava
FRheather
FRherbal
FRhibiscus
FRhollyberry
FRhoneysuckle
FRhuckleberry
FRhyacinth
FRhydrangea
FRiris blossom
FRivy
FLjackfruit
FRjasmin
FRjonquil
 joop
FRjuniper berry
FRkewda
FRkiwi
 kiwi blossom
FRkumquat
FRlavandin
FRlavender
FRleather
FRlemon
FRlemongrass
FRlilac
FRlily
FRlily of the valley
FRlime
FL/FRlinaloe wood
FRlinden flower
FRloganberry
FRlotus
FRlychee
FRmagnolia
FRmango
FRmango flower
 melon watermelon muskmelon cantaloupe
 millefleurs
FRmimosa
FRmint
FRmulberry
FRmusk
FRnarcissus
FRneroli
 new car
 ocean sea
FRorange
FRorange blossom
FRorchid
FRpansy
FRpapaya
FRpassion blossom
FRpassion fruit
FRpeach
FRpeach blossom
FRpear
FRpear blossom
FLpear prickly pear
FRpeony
 pert plus
 petal flower petal
FL/FRpetitgrain bergamot petitgrain
FL/FRpetitgrain lime petitgrain
FRpetunia
FRphlox
FRpina colada
FRpineapple
FRplum
 plum blossom
 plum mirabille blossom
FRpomegranate
 poppy
FRpotpourri
FLpraline
 privet
 privet blossom
FRquince
FRraspberry
FRrhubarb
FRrose
FRrose tea rose
FRrose white rose
 rose wild rose
FRsaffron
FRsandalwood
FRscented stock
FRspice
FLstarfruit
FRstrawberry
FRsweet pea
FRtangerine
FLtea
 tide
FRtoffee
FLtropical
FRtuberose
FRtulip
FRvanilla
FRviolet
FRviolet leaf
FRwallflower
FRwintergreen
FRwisteria
FRwoody
FRyew
FRylang ylang
 
Occurrence (nature, food, other):note
 not found in nature
 salvia officinalis oil england @ 0.10%
Data GC Search Trop Picture
 
Synonyms:
 cyclohexal
3-cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-
3 and 4-(4-hydroxy-4-methyl pentyl) cyclohex-3-ene-1-carbaldehyde
4-(4-hydroxy-4-methyl pentyl) cyclohex-3-ene-1-carbaldehyde
3 and 4-(4-hydroxy-4-methyl pentyl)-3-cyclohexene-1-carboxaldehyde
4-(4-hydroxy-4-methyl pentyl)-3-cyclohexene-1-carboxaldehyde
4-(4-hydroxy-4-methylpentyl)-1-cyclohex-3-enecarboxaldehyde
4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbaldehyde
3 and 4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde
4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde
4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehye
4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene carbaldehyde
3 and 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
4-(4-hydroxy-4-methylpentyl)cyclohex-3-enecarbaldehyde
 hydroxyisohexyl 3-cyclohexene carboxaldehyde
4,4-hydroxymethyl pentyl cyclohexene carbaldehyde
 kovanol (Takasago)
 kovyral
 landolal
 lanyral
 leerall
 lydoucal (A.C.S. International)
 lyral (IFF)
 lysinal
 mugonal
 

Articles:

PubMed:Baseline series fragrance markers fail to predict contact allergy.
PubMed:Postnatal odorant exposure induces peripheral olfactory plasticity at the cellular level.
PubMed:Multicentre patch testing with fragrance mix II and hydroxyisohexyl 3-cyclohexene carboxaldehyde by the Swedish Contact Dermatitis Research Group.
PubMed:Application of Purpald® for determination of 3-cyclohexene-1-carboxaldehyde and hydroxyisohexyl 3-cyclohexene carboxaldehyde.
PubMed:Hydroxyisohexyl 3-cyclohexene carboxaldehyde (lyral) in patch test preparations under varied storage conditions.
PubMed:Categorization of fragrance contact allergens for prioritization of preventive measures: clinical and experimental data and consideration of structure-activity relationships.
PubMed:Risk factors associated with sensitization to hydroxyisohexyl 3-cyclohexene carboxaldehyde.
PubMed:Odorant responsiveness of embryonic mouse olfactory sensory neurons expressing the odorant receptors S1 or MOR23.
PubMed:Results of patch testing with fragrance mix 1, fragrance mix 2, and their ingredients, and Myroxylon pereirae and colophonium, over a 21-year period.
PubMed:Two fragrance chemicals may act as toxicants via TRPA1 stimulation rather than via direct mitochondrial action.
PubMed:Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: protection by antioxidants.
PubMed:Allergic contact dermatitis to fragrances: part 2.
PubMed:Prevalence of allergic contact dermatitis caused by hydroxyisohexyl 3-cyclohexene carboxaldehyde has not changed in Denmark.
PubMed:Is hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitization declining in central Europe?
PubMed:Patch tests with fragrance mix II and its components.
PubMed:An odor-specific threshold deficit implicates abnormal cAMP signaling in youths at clinical risk for psychosis.
PubMed:Contact allergy to the 26 specific fragrance ingredients to be declared on cosmetic products in accordance with the EU cosmetics directive.
PubMed:[Current contact allergens].
PubMed:Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens.
PubMed:Patch-testing with fragrance mix II.
PubMed:Can exposure limitations for well-known contact allergens be simplified? An analysis of dose-response patch test data.
PubMed:Deodorants are the leading cause of allergic contact dermatitis to fragrance ingredients.
PubMed:Fragrance allergens in 'specific' cosmetic products.
PubMed:Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) as allergen: experience from a contact dermatitis unit.
PubMed:Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy.
PubMed:Patch testing with fragrance mix II: results of the IVDK 2005-2008.
PubMed:Olfactory sensitivity for sperm-attractant aromatic aldehydes: a comparative study in human subjects and spider monkeys.
PubMed:Fragrance contact allergy: a 4-year retrospective study.
PubMed:Fragrance allergy: assessing the safety of washed fabrics.
PubMed:Determination of suspected allergens in cosmetic products by headspace-programmed temperature vaporization-fast gas chromatography-quadrupole mass spectrometry.
PubMed:A new IFRA Standard on the fragrance ingredient, hydroxyisohexyl 3-cyclohexene carboxaldehyde.
PubMed:Fragrance contact allergy in Iran.
PubMed:Clinical relevance of positive patch test reactions to the 26 EU-labelled fragrances.
PubMed:The dose-response relationship between the patch test and ROAT and the potential use for regulatory purposes.
PubMed:Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients.
PubMed:Expression patterns of odorant receptors and response properties of olfactory sensory neurons in aged mice.
PubMed:Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholds.
PubMed:Polyvalent type IV sensitizations to multiple fragrances and a skin protection cream in a metal worker.
PubMed:[Facial allergic contact dermatitis. Data from the IVDK and review of literature].
PubMed:An odor-specific threshold deficit implicates abnormal intracellular cyclic AMP signaling in schizophrenia.
PubMed:Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) is still a frequent allergen.
PubMed:Allergic contact dermatitis from lyral in an aerosol deodorant.
PubMed:Allergic contact dermatitis to a perfume containing lyral.
PubMed:Contact allergy in patients with rosacea: a clinic-based, prospective epidemiological study.
PubMed:Frequency of and trends in fragrance allergy over a 15-year period.
PubMed:Recommendation to include fragrance mix 2 and hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) in the European baseline patch test series.
PubMed:Fragrance ingredient labelling in products on sale in the U.K.
PubMed:High-performance liquid chromatographic method for the simultaneous determination of 24 fragrance allergens to study scented products.
PubMed:Selected important fragrance sensitizers in perfumes--current exposures.
PubMed:Patch test results with patients' own perfumes, deodorants and shaving lotions: results of the IVDK 1998-2002.
PubMed:Experimental elicitation with hydroxyisohexyl-3-cyclohexene carboxaldehyde-containing deodorants.
PubMed:[Sensitization to Lyral].
PubMed:Delayed-type hypersensitivity to fragrance materials in a select North American population.
PubMed:Odorant responses of olfactory sensory neurons expressing the odorant receptor MOR23: a patch clamp analysis in gene-targeted mice.
PubMed:Fragrance contact dermatitis in Korea: a joint study.
PubMed:Clinical update on contact allergy.
PubMed:Lyral: a fragrance allergen.
PubMed:Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products.
PubMed:Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix.
PubMed:Rosacea and contact allergy to cosmetics and topical medicaments--retrospective analysis of multicentre surveillance data 1995-2002.
PubMed:Cosmetic allergy: incidence, diagnosis, and management.
PubMed:[Allergy to cosmetics. I. Fragrances].
PubMed:Functional characterization of a mouse testicular olfactory receptor and its role in chemosensing and in regulation of sperm motility.
PubMed:The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands.
PubMed:Fragrance allergy in patients with hand eczema - a clinical study.
PubMed:Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen.
PubMed:[Epidemiologic surveillance of contact allergens. The "monitoring series" of IVDK (Information Network ofDermatologic Clinics for Detection and Scientific Evaluation of Contact Allergy].
PubMed:Cross-adaptation between olfactory responses induced by two subgroups of odorant molecules.
PubMed:Hydroxymethyl pentylcyclohexene- carboxaldehyde (Lyral) as a fragrance allergen in the UK.
PubMed:Principles and methodology for identification of fragrance allergens in consumer products.
PubMed:Further important sensitizers in patients sensitive to fragrances.
PubMed:Lyral has been included in the patch test standard series in Germany.
PubMed:Blocking adenylyl cyclase inhibits olfactory generator currents induced by "IP(3)-odors".
PubMed:Regulation of cutaneous allergic reaction by odorant inhalation.
PubMed:Lyral is an important sensitizer in patients sensitive to fragrances.
PubMed:Allergic contact dermatitis from the fragrance ingredient Lyral in underarm deodorant.
PubMed:Odorants selectively activate distinct G protein subtypes in olfactory cilia.
PubMed:Towards structural models of molecular recognition in olfactory receptors.
PubMed:Existence of multiple receptors in single neurons: responses of single bullfrog olfactory neurons to many cAMP-dependent and independent odorants.
PubMed:Patch testing with fragrances: results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes.
PubMed:Chemosensitivity of the osphradium of the pond snail Lymnaea stagnalis
PubMed:Allergic contact dermatitis from the synthetic fragrances Lyral and acetyl cedrene in separate underarm deodorant preparations.
PubMed:Molecular modeling of ligand-receptor interactions in the OR5 olfactory receptor.
PubMed:A quantitative in vitro assay for the evaluation of phototoxic potential of topically applied materials.
 
Notes:
Gives good body. waxy floral fruity accord: 0.05 - leerall 0.01 - aldehyde C-14 0.05 - aldehyde C18 10% 0.01 - musk gx 0.01 - raspberry ketone 10% 0.01 - aldehyde C-16 10%
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy