EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

(E,E)-farnesol
all-(E)-farnesol

Supplier Sponsors

Name:(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
CAS Number: 106-28-5Picture of molecule3D/inchi
FDA UNII:X23PI60R17
Nikkaji Web:J5.049K
Beilstein Number:1763926
MDL:MFCD00002918
XlogP3-AA:4.80 (est)
Molecular Weight:222.37142000
Formula:C15 H26 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 97.00 to 100.00 sum of isomers
Food Chemicals Codex Listed: No
Specific Gravity:0.88400 to 0.88900 @ 25.00 °C.
Pounds per Gallon - (est).: 7.356 to 7.397
Refractive Index:1.48700 to 1.49400 @ 20.00 °C.
Boiling Point: 283.00 to 284.00 °C. @ 760.00 mm Hg
Boiling Point: 137.00 °C. @ 3.00 mm Hg
Vapor Pressure:0.000370 mm/Hg @ 25.00 °C. (est)
Vapor Density:>1 ( Air = 1 )
Flash Point: 230.00 °F. TCC ( 110.00 °C. )
logP (o/w): 5.314 (est)
Soluble in:
 alcohol
 water, 1.287 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: floral
Odor Strength:low
muguet floral sweet lily waxy
Odor Description:at 100.00 %. mild muguet floral sweet lily waxy
Odor and/or flavor descriptions from others (if found).
Bedoukian Research
(e,e)-FARNESOL ≥97.0% (sum of isomers), FCC, Kosher
Odor Description:subtle, green, floral
Used in rose and other floral compositions.
Taste Description:green
Can be used as a fresh note in sour, tart fruits such as kiwi, carambola (star fruit) and green apples.
 
Cosmetic Information:
None found
 
Suppliers:
Bedoukian Research
(e,e)-FARNESOL
≥97.0% (sum of isomers), FCC, Kosher
Odor: subtle, green, floral
Use: Used in rose and other floral compositions.
Flavor: green
Can be used as a fresh note in sour, tart fruits such as kiwi, carambola (star fruit) and green apples.
BOC Sciences
For experimental / research use only.
(E,E)-FARNESOL 97+% FCC
Penta International
TRANS, TRANS-FARNESOL
Santa Cruz Biotechnology
For experimental / research use only.
trans,trans-Farnesol
Sigma-Aldrich: Aldrich
For experimental / research use only.
trans,trans-Farnesol 96%
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 6000 mg/kg
THERAP
27,893,1972

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
27,893,1972

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:  0.08 % (1)
Category 2:  0.11 %
Category 3:  0.40 %
Category 4:  1.20 %
Category 5:  0.60 %
Category 6:  2.00 % (1)
Category 7:  0.20 %
Category 8:  2.00 %
Category 9:  5.00 %
Category 10:  2.50 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for (E,E)-farnesol flavor usage levels up to:
  2.0000 ppm in the finished product.
 
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):106-28-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :445070
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
Chemidplus:0000106285
RTECS:JR4979000 for cas# 106-28-5
 
References:
 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):445070
Pubchem (sid):135024870
Flavornet:106-28-5
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C01126
HMDB (The Human Metabolome Database):Search
FooDB:FDB014516
YMDB (Yeast Metabolome Database):YMDB00404
Export Tariff Code:2905.22.0000
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•biomite active ingredient 0.1670% farnesol, 0.4170% nerolidol, 0.4170% 3,7-dimethyl-6-octen-1-ol, 0.4170% geraniol •stirrup - m active ingredient 0.9720% farnesol, 0.7880% nerolidol
 
Potential Blenders and core components note
For Odor
aldehydic
adoxal (Givaudan)
FL/FR
citronellyl oxyacetaldehyde
FL/FR
9-
decenal
FL/FR
lily pentanal
FR
mandarine undecenal
FL/FR
muguet undecadienal
FR
nonanal (aldehyde C-9)
FL/FR
(Z)-8-
undecenal
FR
animal
para-
cresyl isobutyrate
FL/FR
para-
cresyl phenyl acetate
FL/FR
balsamic
linalyl cinnamate
FL/FR
citrus
benzyl anthranilate
FR
citronellyl nitrile
FR
citrus ocimenol
FR
(Z)-4-
decenal
FL/FR
myrmac aldehyde
FR
tetrahydromyrcenol
FR
10-
undecen-1-ol
FL/FR
floral
alpha-
amyl cinnamaldehyde dimethyl acetal
FL/FR
alpha-
butyl cinnamaldehyde
FL/FR
4-iso
butyl cyclohexane propanal
FR
citronellyl ethoxalate
FR
corps popinal
FR
para-
cresyl propionaldehyde
CS
cumin carbinol
FR
cuminyl acetaldehyde
FL/FR
cyclamen aldehyde / methyl anthranilate schiff's base
FR
cyclamen homoaldehyde
FR
cyclohexyl ethyl alcohol
FL/FR
cyclohexyl propanol
FR
2-
decalinol
FR
2,5-
dimethyl-2-indan methanol
FR
4-
ethyl cyclohexane propanal
FR
ethyl linalyl acetal
FR
floral butanal
FR
floral pyranol
FR
floral specialty
FR
freesia acetate
FR
gardenia decalone
FR
hawthorn ethanol
FR
(Z)-4-
hepten-2-yl salicylate
FR
hexyl 2-furoate
FL/FR
hydroxycitronellal
FL/FR
hydroxycitronellal / methyl anthranilate schiff's base
FR
hydroxycitronellal diethyl acetal
FL/FR
hydroxycitronellal dimethyl acetal
FL/FR
hydroxycitronellal distillation residue distillates
FR
hydroxycitronellal nitrile
FR
hydroxycitronellal propylene glycol acetal
FL/FR
hydroxycitronellal residue
FR
hydroxycitronellol
FL/FR
jasimia
FR
leerall
FR
leerall / methyl anthranilate schiff's base
FR
calla
lily fragrance
FR
lily of the valley specialty
FR
lily propanol
FR
lilyall
FR
lilyall / methyl anthranilate schiff's base
FR
lilyall substitute
FR
linalyl benzoate
FL/FR
linalyl propionate
FL/FR
linden blossom fragrance
FR
linden blossom specialty
FR
magnolia cyclohexanol
FR
magnolia decadienal
FR
methoxycitronellal
FR
methyl citronellate
FL/FR
4-
methyl cyclohexane propanal
FR
2-
methyl octanal
FL/FR
1-
methyl-3-(2-methyl propyl) cyclohexanol
FR
3-
methyl-6-ethyl-5-octen-1-ol
FR
muguet butanal
FR
muguet butanol
FR
muguet carbaldehyde
FR
muguet carbinol
FL/FR
muguet carboxaldehyde
FR
muguet ethanol
FR
muguet nitrile
FR
muguet octadienol
FR
muguet propanol
FR
muguet shiseol
FL/FR
muguet specialty
FR
3-
nonanon-1-yl acetate
FL/FR
octahydro-4,7-methano-1H-indene-5-acetaldehyde
FR
octahydro-4,7-methano-1H-indene-5-acetaldehyde + 6-methyl-octahydro-4,7-methano-indene-5-carbaldehyd
FR
phenethyl hexanoate
FL/FR
phenyl glycol diacetate
FR
4-
propyl cyclohexane propanal
FR
alpha-
terpinyl anthranilate
FL/FR
tetrahydrolinalool
FL/FR
ylang ylang flower oil
FL/FR
fruity
methyl heptanoate
FL/FR
green
heptyl formate
FL/FR
phenyl acetaldehyde diethyl acetal
FL/FR
phenyl hexyl acetate
FR
herbal
dimethyl benzyl carbinyl formate
FL/FR
marine
ozone propanal
FR
waxy
ethyl laurate
FL/FR
hexadecanol
FL/FR
woody
hydroxycitronellal diisotridecyl acetal
FR
For Flavor
No flavor group found for these
alpha-
amyl cinnamaldehyde dimethyl acetal
FL/FR
9-
decenal
FL/FR
dimethyl benzyl carbinyl formate
FL/FR
hydroxycitronellal propylene glycol acetal
FL/FR
mandarine undecenal
FL/FR
2-
methyl octanal
FL/FR
phenyl acetaldehyde diethyl acetal
FL/FR
alpha-
terpinyl anthranilate
FL/FR
10-
undecen-1-ol
FL/FR
alpha-
butyl cinnamaldehyde
FL/FR
aldehydic
aldehydic
nonanal (aldehyde C-9)
FL/FR
aromatic
para-
cresyl isobutyrate
FL/FR
citrus
citronellyl oxyacetaldehyde
FL/FR
(Z)-4-
decenal
FL/FR
fatty
heptyl formate
FL/FR
floral
linalyl benzoate
FL/FR
methyl citronellate
FL/FR
muguet carbinol
FL/FR
muguet shiseol
FL/FR
tetrahydrolinalool
FL/FR
ylang ylang flower oil
FL/FR
fruity
linalyl cinnamate
FL/FR
methyl heptanoate
FL/FR
3-
nonanon-1-yl acetate
FL/FR
green
cuminyl acetaldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
hexyl 2-furoate
FL/FR
herbal
linalyl propionate
FL/FR
melon
hydroxycitronellal diethyl acetal
FL/FR
phenolic
para-
cresyl phenyl acetate
FL/FR
powdery
hydroxycitronellol
FL/FR
waxy
adoxal (Givaudan)
FL/FR
ethyl laurate
FL/FR
hexadecanol
FL/FR
hydroxycitronellal
FL/FR
hydroxycitronellal dimethyl acetal
FL/FR
phenethyl hexanoate
FL/FR
 
Potential Uses:
FRaldehydic
FRfloral
FRlily
FRlily of the valley
 waxy
 
Occurrence (nature, food, other):note
 ambrette seed concrete @ 2.16%
Data GC Search Trop Picture
 ambrette seed oil @ 3.50%
Data GC Search Trop Picture
 boronia absolute @ 0.08%
Data GC Search Trop Picture
 cabocla flower oil brazil @ 0.50%
Data GC Search Trop Picture
 champaca concrete @ 0.20%
Data GC Search Trop Picture
 cinnamon ceylon cinnamon leaf
Search Trop Picture
 clove bud oil @ 1.08%
Data GC Search Trop Picture
 clove leaf oil @ 0.61%
Data GC Search Trop Picture
 clove stem oil india @ 0.69%
Data GC Search Trop Picture
 couroupita guianensis aubl. flower oil brazil @ 16.10%
Data GC Search Trop Picture
 curry fruit oil india @ <0.05%
Data GC Search Trop Picture
 curry leaf oil india @ 0.20%
Data GC Search Trop Picture
 geranium rose-scented oil (pelargonium spp.) cuba @ 0.20%
Data GC Search Trop Picture
 ginger root oil CO2 extract @ 0.88%
Data GC Search Trop Picture
 guava leaf oil cuba @ 0.20%
Data GC Search Trop Picture
 jasmin absolute china (from concrete) @ 0.09%
Data GC Search Trop Picture
 jasmin sambac absolute egypt @ 1.30%
Data GC Search Trop Picture
 palmarosa oil @ 1.90%
Data GC Search Trop Picture
 rose oil otto bulgaria @ 1.98%
Data GC Search Trop Picture
 skimmia laureola oil @ 0.7%
Data GC Search Trop Picture
 thevetia peruviana (pers.) k. schum. flower oil brazil @ 0.10%
Data GC Search Trop Picture
 ylang ylang oil @ 0.84%
Data GC Search Trop Picture
 ylang ylang oil CO2 extract @ 1.39%
Data GC Search Trop Picture
 
Synonyms:
2,6-di-trans-farnesol
2,6,10-dodecatrien-1-ol, 3,7,11-trimethyl-, (2E,6E)-
2,6,10-dodecatrien-1-ol, 3,7,11-trimethyl-, (E,E)-
(2-trans,6-trans)-farnesol
(2E,6E)-farnesol
(E,E)-2,6-farnesol
(E)-farnesol
2-trans,6-trans-farnesol
all-(E)-farnesol
all-trans-farnesol
trans, trans-farnesol
trans,trans-farnesol
(2E,6E)-3,7,11-trimethyl-1-dodeca-2,6,10-trienol
(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
(E,E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
trans,trans-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
(2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trien-1-ol
3,7,11-trimethyldodeca-2-trans,6-trans,10-trien-1-ol
(2-trans,6-trans)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
 

Articles:

PubMed:Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed:Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed:Essential oil composition and antimicrobial activities of two closely related species, Alpinia mutica Roxb. and Alpinia latilabris Ridl., from Peninsular Malaysia.
PubMed:Gold(I) as an artificial cyclase: short stereodivergent syntheses of (-)-epiglobulol and (-)-4β,7α- and (-)-4α,7α-aromadendranediols.
PubMed:Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models.
PubMed:[Tobacco--once a medicinal plant. Does it contain substances with medicinal properties?].
PubMed:Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
PubMed:Chemical composition and in vitro antimicrobial and antioxidant activities of Citrus aurantium l. flowers essential oil (Neroli oil).
PubMed:Characterization of essential oil from Citrus aurantium L. flowers: antimicrobial and antioxidant activities.
PubMed:Determination of E,E-farnesol in Makgeolli (rice wine) using dynamic headspace sampling and stir bar sorptive extraction coupled with gas chromatography-mass spectrometry.
PubMed:Study of trans-trans farnesol effect on hyphae formation by Yarrowia lipolytica.
PubMed:β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells.
PubMed:Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli.
PubMed:Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens.
PubMed:Specific involvement of two amino acid residues in cis-nerolidol binding to odorant-binding protein 5 AlinOBP5 in the alfalfa plant bug, Adelphocoris lineolatus (Goeze).
PubMed:A convergent stereocontrolled total synthesis of (-)-terpestacin.
PubMed:Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils.
PubMed:Quorum sensing activity in Ophiostoma ulmi: effects of fusel oils and branched chain amino acids on yeast-mycelial dimorphism.
PubMed:Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis).
PubMed:Effect of exogenous administration of Candida albicans autoregulatory alcohols in a murine model of hematogenously disseminated candidiasis.
PubMed:Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed:Drimenol: A versatile synthon for compounds with trans-drimane skeleton.
PubMed:Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms.
PubMed:Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.
PubMed:Application of a multidimensional gas chromatography system with simultaneous mass spectrometric and flame ionization detection to the analysis of sandalwood oil.
PubMed:Variation in volatile leaf oils of eleven eucalyptus species harvested from korbous arboreta (Tunisia).
PubMed:The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species.
PubMed:Candida species extracellular alcohols: production and effect in sessile cells.
PubMed:Production of geranylgeraniol on overexpression of a prenyl diphosphate synthase fusion gene in Saccharomyces cerevisiae.
PubMed:Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem.
PubMed:Determination of the volatile composition in essential oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by gas chromatography/mass spectrometry (GC/MS).
PubMed:Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography.
PubMed:Flowerhead volatile oil composition of soilless culture-grown Chrysanthemum balsamita L.
PubMed:Quantification approach for assessment of sparkling wine volatiles from different soils, ripening stages, and varieties by stir bar sorptive extraction with liquid desorption.
PubMed:Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols.
PubMed:Optimisation of stir bar sorptive extraction and liquid desorption combined with large volume injection-gas chromatography-quadrupole mass spectrometry for the determination of volatile compounds in wines.
PubMed:Synthesis of cordiaquinones B, C, J, and K on the basis of a bioinspired approach and the revision of the relative stereochemistry of cordiaquinone C.
PubMed:Secretion of E,E-farnesol and biofilm formation in eight different Candida species.
PubMed:Morphogenesis control in Candida albicans and Candida dubliniensis through signaling molecules produced by planktonic and biofilm cells.
PubMed:Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry.
PubMed:The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes.
PubMed:Analysis of the essential oil of Grindelia discoidea.
PubMed:Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways.
PubMed:Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design.
PubMed:Determination of terpenes in tequila by solid phase microextraction-gas chromatography-mass spectrometry.
PubMed:A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol.
PubMed:Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke.
PubMed:Volatile constituents of redblush grapefruit (Citrus paradisi) and pummelo (Citrus grandis) peel essential oils from Kenya.
PubMed:Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog.
PubMed:Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum.
PubMed:Responses to sex pheromone and plant odours by olfactory receptor neurons housed in sensilla auricillica of the codling moth, Cydia pomonella (Lepidoptera: Tortricidae).
PubMed:Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
PubMed:Comprehensive two-dimensional gas chromatography with flame ionization and time-of-flight mass spectrometry detection: qualitative and quantitative analysis of West Australian sandalwood oil.
PubMed:Farnesol-DMPC phase behaviour: a (2)H-NMR study.
PubMed:Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs.
PubMed:Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants.
PubMed:The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
PubMed:Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor.
PubMed:African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol.
PubMed:Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
PubMed:Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol.
PubMed:Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed:Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin.
PubMed:Synthesis and biological evaluation of the geometric farnesylated analogues of the a-factor mating peptide of Saccharomyces cerevisiae.
PubMed:Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability.
PubMed:Sex pheromone mimicry in the early spider orchid (ophrys sphegodes): patterns of hydrocarbons as the key mechanism for pollination by sexual deception.
PubMed:Farnesyl anthranilate suppresses the growth, in vitro and in vivo, of murine B16 melanomas.
PubMed:Pleiotropic effects of statins in atherosclerosis and diabetes.
PubMed:Comparison of headspace techniques for sampling volatile natural products in a dynamic system.
PubMed:Direct vascular effects of HMG-CoA reductase inhibitors.
PubMed:Studies on the Synthesis of Elegan-Type Linear Diterpenes: The Efficient Total Syntheses of Eleganolone, Eleganolone Acetate, Elegandiol, Eleganonal, and Epoxyeleganolone
PubMed:Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells.
PubMed:Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.
PubMed:Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation.
PubMed:Male sex pheromone of a giant danaine butterfly,Idea leuconoe.
PubMed:Identification and characterization of geranylgeraniol kinase and geranylgeranyl phosphate kinase from the Archaebacterium Sulfolobus acidocaldarius.
PubMed:Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine.
PubMed:Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: effect of phosphatidylcholine.
PubMed:Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture.
PubMed:Requirement for isoprenoid-dependent posttranslational modifications in the cell-cycle progression of human breast-cancer cells.
PubMed:Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol.
PubMed:Chemical analysis of temporal gland secretions collected from an Asian bull elephant during a four-month musth episode.
PubMed:The conformation of dolichol.
PubMed:Chemosensory responses in two species of elephants to constituents of temporal gland secretion and musth urine.
PubMed:Odor mimetism? : Key substances inOphrys lutea-Andrena pollination relationship (Orchidaceae: Andrenidae).
PubMed:Total synthesis of chain-length-uniform dolichyl phosphates and their fitness to accept hexoses in the enzymatic formation of lipoglycans.
PubMed:Constituents of temporal gland secretion of the African elephant,Loxodonta africana.
PubMed:The Nasonov pheromone of the honeybeeApis mellifera L. (Hymenoptera, Apidae). Part II. Bioassay of the components using foragers.
PubMed:Photosynthetic pigments of green sulfur bacteria. The esterifying alcohols of bacteriochlorophylls c from Chlorobium limicola.
PubMed:Levels of short-chain fatty acids and of abscisic acid in water-stressed and non-stressed leaves and their effects on stomata in epidermal strips and excised leaves.
PubMed:Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes.
PubMed:Comparison between Biosynthesis of ent-Kaurene in Germinating Tomato Seeds and Cell Suspension Cultures of Tomato and Tobacco.
PubMed:Detection and preliminary identification of endogenous antitranspirants in water-stressed Sorghum plants.
PubMed:Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata.
PubMed:All-trans-farnesol: a naturally occurring antitranspirant?
PubMed:Synthesis of cecropia juvenile hormone from trans,trans-farnesol.
PubMed:Lipid metabolism in helminth parasites--VI. Synthesis of 2-cis,6-trans farnesol by Hymenolepis diminuta (Cestoda).
 
Notes:
Flavouring ingredient Farnesol is a natural organic compound which is an acyclic sesquiterpene alcohol found as a colorless liquid. It is insoluble in water, but miscible with oils. It is the building block of most, and possibly all, acyclic sesquiterpenoids and is an important starting compound for organic synthesis. [Wikipedia]
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