white pepper oil
white piper nigrum fruit oil
tsca definition 2008: extractives and their physically modified derivatives. piper nigrum, labiatae.
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Fragrance Demo Formulas
Name: piper nigrum l. fruit oil white
CAS Number: 8006-82-4 
ECHA EC Number: 284-524-7
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 2851  white pepper oil
FDA Regulation:
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 water, 4.581 mg/L @ 25 °C (est)
Insoluble in:
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Organoleptic Properties:
Odor Type: spicy
Odor Strength: medium
Odor Description:
at 100.00 %. 
Taste Description:
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Cosmetic Information:
None found
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Bristol Botanicals
White Pepper essential oil Piper nigrum, India
Odor: Volatiles from the Essential Oil
Flavor: Spicy, peppery, fruity, terpenic, not hot
Lluch Essence
Plant Lipids
white Pepper Oil
Synthite Industries
White Pepper Oil
E-books and Brochures
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Safety Information:
European information :
Most important hazard(s):
Xn - Harmful.
R 10 - Flammable.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
R 65 - Harmful: may cause lung damage if swallowed.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 36 - Wear suitable protective clothing.
S 62 - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -0.60000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
NLM Hazardous Substances Data Bank: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 8006-82-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 piper nigrum l. fruit oil white
Chemidplus: 0008006824
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 piper nigrum l. fruit oil white
Canada Domestic Sub. List: 8006-82-4
Pubchem (sid): 135333140
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.29.6000
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
For Odor
 angelica seed oilFL/FR
 angelica seed oil CO2 extractFL/FR
bitter fennel seed oil spainFR
 amyris wood oilFL/FR
 copaiba balsam oilFL/FR
 hemlock western oil (tsuga heterophylla) canadaFR
 tolu balsam oilFL/FR
 canarium luzonicum gumFL/FR
 canarium luzonicum oilFL/FR
 elemi resinoidFL/FR
 atractylis root oilFR
 croton eluteria bark oilFL/FR
 ethyl vinyl ketoneFL/FR
 grains of paradise oilFL/FR
black pepper absoluteFL/FR
 pepper hexanoneFR
black pepper oilFL/FR
black pepper oleoresinFL/FR
 pepper tree berry oilFL/FR
 zvoulimba leaf oilFR
 juniperus communis fruit oilFL/FR
 guaiacwood oil 20% in gurjun balsam oilFR
 methyl vetivateFR
 sugi wood oilFR
For Flavor
No flavor group found for these
 grains of paradise oilFL/FR
 angelica seed oilFL/FR
 copaiba balsam oilFL/FR
 tolu balsam oilFL/FR
 canarium luzonicum gumFL/FR
 canarium luzonicum oilFL/FR
 elemi resinoidFL/FR
 angelica seed oil CO2 extractFL/FR
 croton eluteria bark oilFL/FR
 cubeb oleoresinFL
 ethyl vinyl ketoneFL/FR
black pepper absoluteFL/FR
black pepper oilFL/FR
black pepper oleoresinFL/FR
 pepper tree berry oilFL/FR
 juniperus communis fruit oilFL/FR
 amyris wood oilFL/FR
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Potential Uses:
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Occurrence (nature, food, other): note
 pepper black pepper seed
Search Trop  Picture
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white piper nigrum fruit oil
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Perfumer & Flavorist: Progress in Essential Oils
PubMed: The effect of olfactory stimuli on the balance ability of stroke patients.
PubMed: Antifungal activity and computational study of constituents from Piper divaricatum essential oil against Fusarium infection in black pepper.
PubMed: Anti-inflammatory, antinociceptive activity of an essential oil recipe consisting of the supercritical fluid CO2 extract of white pepper, long pepper, cinnamon, saffron and myrrh in vivo.
PubMed: The effectiveness of essential oils for patients with neck pain: a randomized controlled study.
PubMed: Essential Oils in Ginger, Hops, Cloves, and Pepper Flavored Beverages-A Review.
PubMed: Anti-biofilm, anti-hemolysis, and anti-virulence activities of black pepper, cananga, myrrh oils, and nerolidol against Staphylococcus aureus.
PubMed: Combined effects of gamma-irradiation and modified atmosphere packaging on quality of some spices.
PubMed: Isolation, characterization and identification of pericarp-degrading bacteria for the production of off-odour-free white pepper from fresh berries of Piper nigrum L.
PubMed: Antioxidative properties and inhibition of key enzymes relevant to type-2 diabetes and hypertension by essential oils from black pepper.
PubMed: An overview of the evidences of herbals for smoking cessation.
PubMed: [Dietary risk factors of undifferenced nasopharyngeal carcinoma : a case-control study].
PubMed: Black pepper and health claims: a comprehensive treatise.
PubMed: The effects of aromatherapy on nicotine craving on a U.S. campus: a small comparison study.
PubMed: Development of a stable isotope dilution LC-MS/MS method for the Alternaria toxins tentoxin, dihydrotentoxin, and isotentoxin.
PubMed: Efficacy of methyl nonyl ketone as an in-soil repellent for common voles (Microtus arvalis).
PubMed: The repelling effect of plant secondary metabolites on water voles, Arvicola amphibius.
PubMed: Black pepper essential oil to enhance intravenous catheter insertion in patients with poor vein visibility: a controlled study.
PubMed: Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension.
PubMed: Ghrelin, leptin and adiponectin as possible predictors of the hedonic value of odors.
PubMed: Piperine, active substance of black pepper, alleviates hypertension induced by NO synthase inhibition.
PubMed: [Antioxidant properties of essential oils].
PubMed: [Acupoint sticking therapy for treatment of bronchial asthma: a multicenter controlled randomized clinical trial].
PubMed: Chemistry and in vitro antioxidant activity of volatile oil and oleoresins of black pepper (Piper nigrum).
PubMed: Olfactory stimuli and enhanced postural stability in older adults.
PubMed: Growth inhibition of pathogenic bacteria and some yeasts by selected essential oils and survival of L. monocytogenes and C. albicans in apple-carrot juice.
PubMed: Repellence of plant essential oils to Dermanyssus gallinae and toxicity to the non-target invertebrate Tenebrio molitor.
PubMed: Toxicity of botanical formulations to nursery-infesting white grubs (Coleoptera: Scarabaeidae).
PubMed: Olfactory stimulation using black pepper oil facilitates oral feeding in pediatric patients receiving long-term enteral nutrition.
PubMed: Antioxidant activity of commonly consumed plant foods of India: contribution of their phenolic content.
PubMed: A randomized trial of olfactory stimulation using black pepper oil in older people with swallowing dysfunction.
PubMed: Persistency of larvicidal effects of plant oil extracts under different storage conditions.
PubMed: Effects of flavorings, storage conditions, and storage time on survival of Staphylococcus aureus in Sürk cheese.
PubMed: Characterization of peppercorn, pepper oil, and pepper oleoresin by vibrational spectroscopy methods.
PubMed: Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress.
PubMed: Effect of storage on the essential oil composition of Piper nigrum L. fruits of different ripening states.
PubMed: Effect of piperine, the active ingredient of black pepper, on intestinal secretion in mice.
PubMed: [Penetrating intraocular injuries caused by foreign bodies of organic origin] ].
PubMed: Effect of cinnamon, clove and some of their constituents on the Na(+)-K(+)-ATPase activity and alanine absorption in the rat jejunum.
PubMed: Effect of various essential oils on Callosobruchus maculatus (F.) (Coleoptera: Bruchidae).
PubMed: Degradation of the natural mutagenic compound safrole in spices by cooking and irradiation.
PubMed: Production of aflatoxin byAspergillus parasiticus and its control.
PubMed: Labial food challenge in children with food allergy.
PubMed: Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms.
PubMed: Modulatory effects of essential oils from spices on the formation of DNA adduct by aflatoxin B1 in vitro.
PubMed: Aflatoxin contamination in foods and foodstuffs in Tokyo: 1986-1990.
PubMed: Diet, living conditions and nasopharyngeal carcinoma in Tunisia--a case-control study.
PubMed: Organochlorine pesticide residues in different Indian cereals, pulses, spices, vegetables, fruits, milk, butter, Deshi ghee, and edible oils.
PubMed: Tumour reducing and anticarcinogenic activity of selected spices.
PubMed: Relaxant effects on tracheal and ileal smooth muscles of the guinea pig.
PubMed: Aspergillus parasiticus growth and aflatoxin production on black and white pepper and the inhibitory action of their chemical constituents.
PubMed: Collaborative study of a modified method for the extraction of light filth from ground white pepper, cardamon, celery seed, coriander, and ginger.
PubMed: Constituents of peppers: IV. The hydrocarbons of pepper essential oil.
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