EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

delta-hexalactone
hexano-1,5-lactone

Supplier Sponsors

Name:6-methyloxan-2-one
CAS Number: 823-22-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:212-511-8
FDA UNII:C8456O4551
Nikkaji Web:J110.474H
MDL:MFCD00083574
CoE Number:641
XlogP3-AA:1.00 (est)
Molecular Weight:114.14410000
Formula:C6 H10 O2
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
JECFA evaluated delta-hexalactone (CASrn as in Register). Register CASrn refers to the racemate.
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:224 delta-hexalactone
FLAVIS Number:10.010 (Old)
DG SANTE Food Flavourings:10.010 hexano-1,5-lactone
FEMA Number:3167 delta-hexalactone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):823-22-3 ; DELTA-HEXALACTONE
 
Physical Properties:
Appearance:colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.04700 to 1.05300 @ 20.00 °C.
Pounds per Gallon - (est).: 8.722 to 8.772
Refractive Index:1.44900 to 1.45300 @ 20.00 °C.
Melting Point: 31.00 °C. @ 760.00 mm Hg
Boiling Point: 110.00 to 112.00 °C. @ 15.00 mm Hg
Boiling Point: 59.00 to 60.00 °C. @ 0.04 mm Hg
Vapor Pressure:0.145000 mmHg @ 25.00 °C. (est)
Flash Point: 225.00 °F. TCC ( 107.22 °C. )
logP (o/w): 0.431 (est)
Soluble in:
 alcohol
 ether
 water, 3.219e+004 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: herbal
Odor Strength:medium
creamy fruity coconut
Odor Description:at 100.00 %. creamy fruity coconut
Flavor Type: creamy
creamy spicy coconut
Taste Description: creamy spicy coconut
Odor and/or flavor descriptions from others (if found).
Firmenich
HEXALACTONE DELTA min. 98%, Kosher, Halal
Taste Description:Nice creamy, spicy and coconut notes
HEXALACTONE DELTA has the classic lactonic profile with a nice spicy nuance. It is widely used in butter, cream milk, nut and fruit flavors.
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
A.C.S. International
Hexalactone delta
Odor: sweet dry hay creamy fruity
Operational Capabilities
Azelis UK
HEXALACTONE DELTA
Services
BOC Sciences
For experimental / research use only.
delta-Hexalactone 95%
Carbosynth
For experimental / research use only.
delta-Hexalactone
De Monchy Aromatics
delta-Hexalactone
Diffusions Aromatiques
delta-HEXALACTONE
Ernesto Ventós
HEXALACTONE DELTA FIRMENICH 944631
Odor: CREAMY, FRUITY, COCONUT
Ernesto Ventós
HEXALACTONE GAMMA II
Ernesto Ventós
HEXALACTONE GAMMA
Firmenich
HEXALACTONE DELTA
min. 98%, Kosher, Halal
Flavor: Nice creamy, spicy and coconut notes
HEXALACTONE DELTA has the classic lactonic profile with a nice spicy nuance. It is widely used in butter, cream milk, nut and fruit flavors.
Indukern F&F
DELTA-HEXALACTONE
Odor: FRUITY, CACAO
Lluch Essence
delta-HEXALACTONE
Odor: FRUITY, COCOA
M&U International
delta-Hexalactone
Odowell Co.,ltd
Delta hexalactone
PURITY: 98%MIN.
Penta International
DELTA-HEXALACTONE
R C Treatt & Co Ltd
delta-Hexalactone
Sigma-Aldrich
d-Hexalactone, ≥98%, FG
Certified Food Grade Products
Soda Aromatic
delta-Hexalactone C-6
Soda Aromatic
delta-Hexalactone
Synerzine
delta-Hexalactone
TCI AMERICA
For experimental / research use only.
delta-Hexalactone >99.0%(GC)
Vigon International
Hexalactone Delta
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
gavage-rat LD50 13020 mg/kg
(Smyth et al., 1962)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for delta-hexalactone usage levels up to:
  4.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 320.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
 average usual ppmaverage maximum ppm
baked goods: -10.00000
beverages(nonalcoholic): -10.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: -10.00000
fish products: --
frozen dairy: -10.00000
fruit ices: -10.00000
gelatins / puddings: -10.00000
granulated sugar: --
gravies: --
hard candy: -10.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30
View page or View pdf

EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :13204
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
6-methyloxan-2-one
Chemidplus:0000823223
 
References:
 6-methyloxan-2-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:823-22-3
Pubchem (cid):13204
Pubchem (sid):134977956
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB00453
FooDB:FDB008077
Export Tariff Code:2932.20.5050
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
amber
angelica root oil
FL/FR
cistus ladaniferus resinoid
FL/FR
animal
animal carbolactone
FR
civet absolute
FL/FR
costus valerolactone
FR
anisic
para-
anisaldehyde
FL/FR
balsamic
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzyl cinnamate
FL/FR
benzyl salicylate
FL/FR
iso
butyl cinnamate
FL/FR
copaiba balsam oil
FL/FR
ethyl cinnamate
FL/FR
fir balsam absolute
FR
methyl cinnamate
FL/FR
peru balsam oil
FL/FR
tolu balsam
FL/FR
berry
raspberry ketone
FL/FR
buttery
acetoin
FL/FR
caramellic
ethyl maltol
FL/FR
immortelle absolute
FL/FR
cheesy
2-
heptanone
FL/FR
coconut
coconut decanone methyl
FR
coconut naphthalenone
FL/FR
delta-
decalactone
FL/FR
delta-2-
dodecenolactone
FL/FR
gamma-
heptalactone
FL/FR
delta-
heptalactone
FL/FR
delta-
nonalactone
FL/FR
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
gamma-
octalactone
FL/FR
delta-
octalactone
FL/FR
propyl octanoate
FL/FR
tetrahydrojasmone
FR
delta-
undecalactone
FL/FR
wine lactone
FL/FR
coumarinic
phthalide
FL/FR
creamy
butyl lactate
FL/FR
creamy lactone
FL/FR
fatty
(R)-gamma-
decalactone
FL/FR
(S)-gamma-
decalactone
FL/FR
floral
acetophenone
FL/FR
iso
amyl salicylate
FL/FR
iso
butyl salicylate
FL/FR
cananga oil
FL/FR
dihydrojasmone
FL/FR
dihydrojasmone lactone
FL/FR
floral pyranol
FR
heliotropin
FL/FR
heliotropyl acetone
FL/FR
heliotropyl diethyl acetal
FR
hexenyl cyclopentanone
FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
jasmin lactone (IFF)
FL/FR
jasmin pyranone
FL/FR
iso
jasmone
FL/FR
lavender oil
FL/FR
para-
methyl acetophenone
FL/FR
nerolidol
FL/FR
ocean propanal
FL/FR
orris rhizome absolute (iris pallida)
FL/FR
palmarosa oil
FL/FR
2-
pentyl cyclopentanone
FR
phenethyl phenyl acetate
FL/FR
fruity
amyl heptanoate
FL/FR
iso
amyl lactate
FL/FR
iso
amyl octanoate
FL/FR
benzaldehyde
FL/FR
gamma-
decalactone
FL/FR
4-
hydroxybenzyl alcohol
FL/FR
methyl (Z)-5-octenoate
FL/FR
iso
propyl octanoate
FL/FR
(R)-delta-
undecalactone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
2-
undecanone
FL/FR
green
alpha-
decalactone
FL/FR
diphenyl methane
FL/FR
galbanum oil
FL/FR
heptyl heptanoate
FL/FR
3-
phenyl propionaldehyde
FL/FR
hay
hay absolute
FR
herbal
apium graveolens seed oil india
FL/FR
abrialis
lavandin oil
FL/FR
linalyl acetate
FL/FR
origanum oil greece
FL/FR
melon
watermelon ketone
FR
mossy
oakmoss absolute
FL/FR
treemoss absolute
FR
veramoss (IFF)
FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
beta-
naphthyl methyl ether
FL/FR
oily
petal pyranone
FL/FR
powdery
para-
anisyl alcohol
FL/FR
soapy
ethyl undecanoate
FL/FR
spicy
benzyl isoeugenol
FL/FR
croton eluteria bark oil
FL/FR
cubeb oil
FL/FR
iso
eugenyl acetate
FL/FR
ginger root oil china
FL/FR
levisticum officinale root oil
FL/FR
methyl heptadienone
FL/FR
nutmeg oil
FL/FR
sweet
vanilla oleoresin bali
FL/FR
thujonic
armoise oil
FR
tonka
6-
amyl-alpha-pyrone
FL/FR
gamma-
hexalactone
FL/FR
7-
methyl coumarin
CS
mint lactone
FL/FR
tonka bean absolute
FR
whiskey lactone
FL/FR
tropical
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillin
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
waxy
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
ethyl octanoate
FL/FR
ethyl palmitate
FL/FR
methyl laurate
FL/FR
myristyl alcohol
FL/FR
2-
tridecanone
FL/FR
undecanoic acid
FL/FR
woody
guaiacwood oil
FL/FR
methyl cedryl ketone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
sandalwood oil
FL/FR
santall
FR
tobacarol (IFF)
FR
vetiver oil haiti
FL/FR
vetiverol
FL/FR
woody acetate
FR
(Z)-
woody amylene
FR
woody propanol
FR
For Flavor
No flavor group found for these
iso
amyl lactate
FL/FR
cistus ladaniferus resinoid
FL/FR
coconut naphthalenone
FL/FR
alpha-
decalactone
FL/FR
(S)-gamma-
decalactone
FL/FR
(R)-gamma-
decalactone
FL/FR
dimethyl benzofuranone
FL
delta-2-
dodecenolactone
FL/FR
3-
hydroxy-4-phenyl-2-butanone
FL
jasmin lactone (IFF)
FL/FR
massoia bark oil
FL
myristyl alcohol
FL/FR
4-
octen-3-one
FL
propyl octanoate
FL/FR
(R)-
tonka furanone
FL
(R)-delta-
undecalactone
FL/FR
wine lactone
FL/FR
animal
animal
civet absolute
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
iso
butyl cinnamate
FL/FR
copaiba balsam oil
FL/FR
ethyl cinnamate
FL/FR
peru balsam oil
FL/FR
tolu balsam
FL/FR
berry
heliotropyl acetone
FL/FR
raspberry ketone
FL/FR
caramellic
caramel furanone
FL
ethyl maltol
FL/FR
cheesy
2-
heptanone
FL/FR
methyl ketones
FL
cherry
heliotropin
FL/FR
coconut
delta-
decalactone
FL/FR
(R)-
massoia lactone
FL
6-
methyl coumarin
FL
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
delta-
octalactone
FL/FR
cooling
iso
butyl salicylate
FL/FR
coumarinic
phthalide
FL/FR
creamy
acetoin
FL/FR
6-
amyl-alpha-pyrone
FL/FR
para-
anisaldehyde
FL/FR
creamy lactone
FL/FR
5,5-
dibutyl dihydrofuran-2(3H)-one
FL
delta-
dodecalactone
FL/FR
glyceryl 5-hydroxydecanoate
FL/FR
glyceryl 5-hydroxydodecanoate
FL/FR
gamma-
hexalactone
FL/FR
jasmin pyranone
FL/FR
para-
methyl acetophenone
FL/FR
mint lactone
FL/FR
delta-
nonalactone
FL/FR
triacetin
FL
delta-
undecalactone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
dairy
butyl lactate
FL/FR
methyl (Z)-5-octenoate
FL/FR
fatty
2-
tridecanone
FL/FR
floral
cananga oil
FL/FR
dihydrojasmone
FL/FR
linalyl acetate
FL/FR
ocean propanal
FL/FR
fruity
acetyl isovaleryl
FL
amyl heptanoate
FL/FR
iso
amyl octanoate
FL/FR
para-
anisyl alcohol
FL/FR
benzaldehyde
FL/FR
gamma-
decalactone
FL/FR
4-
hydroxybenzyl alcohol
FL/FR
iso
propyl octanoate
FL/FR
grassy
palmarosa oil
FL/FR
green
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
diphenyl methane
FL/FR
galbanum oil
FL/FR
heptyl heptanoate
FL/FR
immortelle absolute
FL/FR
iso
jasmone
FL/FR
methyl heptadienone
FL/FR
nerolidol
FL/FR
oakmoss absolute
FL/FR
3-
phenyl propionaldehyde
FL/FR
herbal
apium graveolens seed oil india
FL/FR
abrialis
lavandin oil
FL/FR
lavender oil
FL/FR
origanum oil greece
FL/FR
honey
phenethyl phenyl acetate
FL/FR
lactonic
delta-
heptalactone
FL/FR
gamma-
heptalactone
FL/FR
gamma-
octalactone
FL/FR
naphthyl
beta-
naphthyl methyl ether
FL/FR
oily
petal pyranone
FL/FR
powdery
acetophenone
FL/FR
beta-
naphthyl ethyl ether
FL/FR
soapy
1-
dodecanol
FL/FR
spicy
benzyl cinnamate
FL/FR
benzyl isoeugenol
FL/FR
benzylidene acetone
FL
croton eluteria bark oil
FL/FR
cubeb oil
FL/FR
iso
eugenyl acetate
FL/FR
ginger root oil china
FL/FR
levisticum officinale root oil
FL/FR
methyl cinnamate
FL/FR
nutmeg oil
FL/FR
sweet
orris rhizome absolute (iris pallida)
FL/FR
vanilla oleoresin bali
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillin
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
waxy
dihydrojasmone lactone
FL/FR
ethyl laurate
FL/FR
ethyl octanoate
FL/FR
ethyl palmitate
FL/FR
ethyl undecanoate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
methyl laurate
FL/FR
undecanoic acid
FL/FR
2-
undecanone
FL/FR
woody
amyris wood oil
FL/FR
guaiacwood oil
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
sandalwood oil
FL/FR
vetiver oil haiti
FL/FR
vetiverol
FL/FR
whiskey lactone
FL/FR
 
Potential Uses:
FRacacia
FRaldehydic
FRallspice
FRalmond
FRamber
FRambrene
FRambrosia
FRangel essence
FRapricot
FRazalea
FRbaby powder
FRbalsam
FRbanana
FRbay rum
FRbayberry
FRbeeswax absolute replacer
FRblue grass
FRbubble gum
FRcarnation
FRcassia
FRcedar
FRcherry
FRcherry blossom
FLchocolate cocoa
FRchristmas
FRchypre
FRclover
FRcoconut
FRcoconut tropical coconut
FRcologne
FRcoronilla
FRcountry meadow
FRcrabapple blossom
FRdeertongue absolute replacer
FRelder flower
FRevergreen
FRfern
FRfetes
FRfir needle oil replacer
 fixer
FRfloral
FRfrangipani plumeria
FRfresh outdoors
FRgardenia
FRgingerbread
FRhawthorn
FRhay new mown hay
FRheliotrope
FRherbal
FRhoneysuckle
FL/FRimmortelle
FRjasmin
FRjuniper berry
FRlavender
FRleather russian leather
FRlemon
FRlime
FRmelon
FRmimosa
FRmint
FRmusk
FLnut
FRopoponax
FRorange blossom
FRorchid
FRoriental
FRpapaya
FRpassion blossom
FL/FRpennyroyal
FRpina colada
FRpine forest
FRpoppy red poppy
FRpowder
FRpumpkin pie
FRrain
FRsandalwood
FRsassafras
 softener
FRsweet grass
FRsweet pea
FRtobacco
FRtonka bean
FRtuberose
FL/FRvalerian
FRvanilla
FRviolet
FRwallflower
FRwisteria
FRwoodruff
FRwoody
FRylang ylang
 
Occurrence (nature, food, other):note
 butter
Search PMC Picture
 coconut oil
Search Trop Picture
 raspberry red raspberry fruit
Search Trop Picture
 strawberry wild strawberry fruit
Search Trop Picture
 tea
Search Trop Picture
 
Synonyms:
d-caprolactone
d-hexalactone
 hexalactone delta
delta-hexalactone FCC
 hexano-1,5-lactone
 hexanoic acid, 5-hydroxy-, d-lactone
d-hexanolactone
5-hexanolide
5-methyl-5-hydroxypentanoic acid lactone
5-methyl-d-valerolactone
d-methyl-d-valerolactone
5-methyl-delta-valerolactone
6-methyloxan-2-one
6-methyltetrahydro-2H-pyran-2-one
6-methylvalerolactone
2H-pyran-2-one, tetrahydro-6-methyl-
 tetrahydro-6-methyl-2H-pyran-2-one
 
 
Notes:
Isol. from coconut oil (Cocos nucifera), heated milk fat, butter, chicken fat and yoghurt. Also in various fruits e.g. papaya, pineapple, raspberry, strawberry and plums [DFC]
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy