EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

musk decanolide
cervolide (Givaudan)

Sponsors

Fragrance Demo Formulas
Name:1,6-dioxacycloheptadecan-7-one
CAS Number: 6707-60-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:229-755-6
FDA UNII:G6U2GR91JI
Nikkaji Web:J76.223G
Beilstein Number:0158802
MDL:MFCD00169821
XlogP3-AA:4.20 (est)
Molecular Weight:256.38576000
Formula:C15 H28 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless clear slightly viscous liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.97900 to 0.98700 @ 20.00 °C.
Pounds per Gallon - est.: 8.156 to 8.222
Boiling Point: 409.00 to 410.00 °C. @ 760.00 mm Hg
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 3.642 (est)
Soluble in:
 alcohol
 water, 1.433 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 detergent
 soap
 
Organoleptic Properties:
Odor Type: musk
Odor Strength:medium
Substantivity:92 hour(s) at 100.00 %
musk woody sweet waxy fruity
Odor Description:at 100.00 %. musk woody sweet brassylate fruity
Luebke, William tgsc, (1984)
Odor sample from: International Flavors & Fragrances Inc.
Odor and/or flavor descriptions from others (if found).
Givaudan
Cervolide
Odor Description:Musky, Powdery
Cervolide has a fine musk note, slightly fruity with a woody background.
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
1,6-Dioxacycloheptadecan-7-one
CG Herbals
Cervolide
Odor: ProfileFine musk note, slightly fruity with a woody background
Use: Extensively used in deodorants and fine fragrances at 2 to 10%. Also commonly employed to enhance other musks in toilet soaps and detergents at 1% dosage.
Diffusions Aromatiques
12 OXAHEXADECANOLIDE
Ernesto Ventós
MUSK 781 (CERVOLIDE)
Odor: SWEET,TENACIOUS,FRUITY MUSK,CLEAN
Givaudan
Cervolide
Odor: Musky, Powdery
Use: Cervolide has a fine musk note, slightly fruity with a woody background.
Keva
12-OHD
Odor: Musk, woody, sweet, fruity
Lluch Essence
CERVOLIDE
Moellhausen
MUSK 174
Penta International
12-OXAHEXADECANOLIDE
SRS Aromatics
12-oxaHEXADECANOLIDE
Odor: Musk, Woody, Sweet, Brassylate, Fruity
The John D. Walsh Company
Cervolide
Vigon International
Cervolide (12-oxa Hexadecanolide)
Odor: Musky, Powdery
 
Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 789, 1982.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 789, 1982.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: fragrance agents
Recommendation for musk decanolide usage levels up to:
  10.0000 % in the fragrance concentrate.
 
Recommendation for musk decanolide flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):6707-60-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23173
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
1,6-dioxacycloheptadecan-7-one
Chemidplus:0006707604
RTECS:EO2975000 for cas# 6707-60-4
 
References:
 1,6-dioxacycloheptadecan-7-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:6707-60-4
Pubchem (cid):23173
Pubchem (sid):134987063
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2932.29.6000
ChemSpider:View
 
Potential Blenders and core components note
For Odor
aldehydic
citrus carbaldehyde
FR
decanal (aldehyde C-10)
FL/FR
dodecanal (aldehyde C-12 lauric)
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
nonanal (aldehyde C-9)
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
amber
amber naphthofuran
FL/FR
amber oxepin
FR
ambrette seed absolute
FL/FR
ambroxan
FL/FR
ambroxide
FL/FR
angelica root oil
FL/FR
cistus ladaniferus resinoid
FR
(cis+trans)-6,6a,7,8,9,9a-
hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
FR
animal
musk indenofuran
FR
anise
sweet
fennel seed oil
FL/FR
anisic
ambrette seed oil
FL/FR
para-
anisaldehyde
FL/FR
balsamic
iso
amyl benzoate
FL/FR
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzophenone
FR
benzyl benzoate
FL/FR
benzyl cinnamate
FL/FR
benzyl salicylate
FL/FR
laevo-
borneol
FL/FR
iso
bornyl acetate
FL/FR
laevo-
bornyl acetate
FL/FR
brachyleana hutchinsii wood oil
FR
iso
butyl cinnamate
FL/FR
cinnamyl alcohol
FL/FR
clover nitrile
FR
ethyl cinnamate
FL/FR
fir balsam absolute
FR
methyl (E)-cinnamate
FL/FR
myrrh oil
FL/FR
peru balsam oil
FL/FR
3-
phenyl propyl alcohol
FL/FR
phenyl salicylate
FR
valerian rhizome absolute
FL/FR
berry
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
caramellic
ethyl maltol
FL/FR
chemical
iso
butyl formate
FL/FR
chocolate
iso
amyl phenyl acetate
FL/FR
citrus
blood
orange oil italy
FL/FR
coconut
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
gamma-
octalactone
FL/FR
earthy
(Z)-
linalool oxide (furanoid)
FL/FR
floral
alpha-
amyl cinnamaldehyde
FL/FR
iso
amyl salicylate
FL/FR
bois de rose oil brazil
FL/FR
citronellol
FL/FR
coriander seed oil
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
dimethyl anthranilate
FL/FR
dimethyl benzyl carbinol
FL/FR
dimethyl benzyl carbinyl butyrate
FL/FR
ethyl phenyl acetate
FL/FR
floral pyranol
FR
gardenia oxide
FR
geraniol
FL/FR
heliotropin
FL/FR
heliotropyl acetone
FL/FR
heliotropyl diethyl acetal
FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hyacinth ether
FR
hydroxycitronellal
FL/FR
beta-
ionone
FL/FR
leerall
FR
lilyall
FR
laevo-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
methyl dihydrojasmonate
FL/FR
2-
methyl naphthalene
FL/FR
mimosa absolute france
FL/FR
muguet octadienol
FR
nonanol
FL/FR
ocean propanal
FL/FR
bitter
orangeflower concrete morocco
FR
orris pyridine 25% IPM
FR
peony alcohol
FR
phenethyl acetate
FL/FR
phenethyl alcohol
FL/FR
phenethyl phenyl acetate
FL/FR
rhodinol
FL/FR
rose butanoate
FL/FR
rose undecene
FR
tea acetate
FR
tetrahydrolinalool
FL/FR
tuberose acetate
FR
violet methyl carbonate
FR
fruity
allyl amyl glycolate
FR
allyl cyclohexyl propionate
FL/FR
amyl hexanoate
FL/FR
iso
amyl hexanoate
FL/FR
artemisia pallens herb oil
FL/FR
cyclohexyl crotonate
FR
(E)-alpha-
damascone
FL/FR
(E)-beta-
damascone
FL/FR
(R)-gamma-
dodecalactone
FL/FR
menthyl isovalerate
FL/FR
2-
nonanone
FL/FR
iso
octyl acetate
FR
osmanthus flower absolute
FL/FR
iso
propenyl acetate
FL/FR
propyl butyrate
FL/FR
tropical indene
FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
acetaldehyde benzyl 2-methoxyethyl acetal
FL/FR
green carboxylate
FR
iso
green methanoindene
FR
(Z)-3-
hexen-1-yl acetate
FL/FR
3-
hexenyl 2-methyl butyrate
FL/FR
hexoxyacetaldehyde dimethyl acetal
FR
(Z)-
leaf acetal
FL/FR
melon nonenoate
FL/FR
methyl heptine carbonate
FL/FR
methyl octine carbonate
FL/FR
3-
phenyl propionaldehyde
FL/FR
rose leaf absolute (rosa centifolia)
FL/FR
violet leaf absolute
FL/FR
hay
hay absolute
FR
tobacco leaf absolute
FL/FR
herbal
carum carvi fruit oil
FL/FR
clary sage oil france
FL/FR
daucus carota fruit oil
FL/FR
delta-
elemene
FL/FR
lavender absolute bulgaria
FL/FR
linalyl acetate
FL/FR
marigold oil mexico
FL/FR
tea leaf absolute
FL/FR
honey
phenyl acetic acid
FL/FR
mentholic
iso
pulegyl acetate
FL/FR
mossy
oakmoss absolute
FL/FR
oriental specialty
FR
veramoss (IFF)
FR
musk
acetyl ethyl tetramethyl tetralin replacer
FR
musk indanone
FR
musty
ketoiso
phorone
FL/FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
opoponax
opoponax resinoid replacer
FR
powdery
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
spicy
allspice oil
FL/FR
benzyl isoeugenol
FL/FR
cassia bark oil china
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
2,5-
dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate
FR
iso
eugenyl acetate
FL/FR
ginger root absolute
FL/FR
grains of paradise oil
FL/FR
methyl heptadienone
FL/FR
methyl isoeugenol
FL/FR
nutmeg oil
FL/FR
black
pepper oil
FL/FR
pimenta acris leaf oil
FL/FR
sweet
vanilla oleoresin bourbon
FL/FR
terpenic
frankincense oil
FL/FR
alpha-
terpineol
FL/FR
thujonic
armoise oil
FR
tonka
coumarin
FR
tonka bean absolute
FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
iso
amyl decanoate
FL/FR
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
1-
undecanol
FL/FR
woody
agarwood oil (aetoxylon sympetalum)
FR
cabreuva wood oil
FR
cistus twig/leaf oil
FL/FR
guaiacwood oil
FL/FR
guaiacwood oil 20% in gurjun balsam oil
FR
gurjun balsam oil
FR
homalomena rubescens root oil
FR
methyl cedryl ketone
FL/FR
delta-
methyl ionone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
sandal pentenol
FL/FR
sandalwood oil
FL/FR
sandalwood oil CO2 extract
FL/FR
santall
FR
spikenard oil CO2 extract
FL/FR
spruce needle oil canada
FL/FR
tobacarol (IFF)
FR
vetiver oil haiti
FL/FR
woody acetate
FR
(Z)-
woody amylene
FR
woody propanol
FR
For Flavor
No flavor group found for these
acetaldehyde benzyl 2-methoxyethyl acetal
FL/FR
ambrette seed oil
FL/FR
ambroxide
FL/FR
cistus twig/leaf oil
FL/FR
(R)-gamma-
dodecalactone
FL/FR
delta-
elemene
FL/FR
grains of paradise oil
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
methyl (E)-cinnamate
FL/FR
delta-
methyl ionone
FL/FR
osmanthus flower absolute
FL/FR
sandal pentenol
FL/FR
spikenard oil CO2 extract
FL/FR
aldehydic
aldehydic
nonanal (aldehyde C-9)
FL/FR
1-
undecanol
FL/FR
amber
amber naphthofuran
FL/FR
anise
sweet
fennel seed oil
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl benzoate
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
ethyl cinnamate
FL/FR
myrrh oil
FL/FR
peru balsam oil
FL/FR
berry
heliotropyl acetone
FL/FR
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
camphoreous
laevo-
borneol
FL/FR
caramellic
ethyl maltol
FL/FR
cheesy
2-
nonanone
FL/FR
cherry
heliotropin
FL/FR
citrus
linalool
FL/FR
laevo-
linalool
FL/FR
blood
orange oil italy
FL/FR
ketoiso
phorone
FL/FR
alpha-
terpineol
FL/FR
coconut
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
creamy
para-
anisaldehyde
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
ethereal
iso
propenyl acetate
FL/FR
fatty
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
iso
amyl phenyl acetate
FL/FR
bois de rose oil brazil
FL/FR
citronellol
FL/FR
dimethyl benzyl carbinyl butyrate
FL/FR
geraniol
FL/FR
linalyl acetate
FL/FR
methyl dihydrojasmonate
FL/FR
ocean propanal
FL/FR
phenethyl alcohol
FL/FR
phenyl acetic acid
FL/FR
rhodinol
FL/FR
tetrahydrolinalool
FL/FR
fruity
allyl cyclohexyl propionate
FL/FR
iso
amyl benzoate
FL/FR
iso
amyl hexanoate
FL/FR
amyl hexanoate
FL/FR
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
artemisia pallens herb oil
FL/FR
(E)-beta-
damascone
FL/FR
(E)-alpha-
damascone
FL/FR
dimethyl anthranilate
FL/FR
menthyl isovalerate
FL/FR
propyl butyrate
FL/FR
rose butanoate
FL/FR
valerian rhizome absolute
FL/FR
grassy
tobacco leaf absolute
FL/FR
green
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
cinnamyl alcohol
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
3-
hexenyl 2-methyl butyrate
FL/FR
(Z)-
leaf acetal
FL/FR
linalool oxide
FL/FR
melon nonenoate
FL/FR
methyl heptadienone
FL/FR
methyl heptine carbonate
FL/FR
methyl octine carbonate
FL/FR
oakmoss absolute
FL/FR
3-
phenyl propionaldehyde
FL/FR
rose leaf absolute (rosa centifolia)
FL/FR
violet leaf absolute
FL/FR
herbal
carum carvi fruit oil
FL/FR
clary sage oil france
FL/FR
coriander seed oil
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
marigold oil mexico
FL/FR
honey
ethyl phenyl acetate
FL/FR
phenethyl acetate
FL/FR
phenethyl phenyl acetate
FL/FR
lactonic
gamma-
octalactone
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
oily
2-
methyl naphthalene
FL/FR
powdery
beta-
naphthyl ethyl ether
FL/FR
rummy
iso
butyl formate
FL/FR
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
1-
dodecanol
FL/FR
spicy
allspice oil
FL/FR
benzyl cinnamate
FL/FR
benzyl isoeugenol
FL/FR
cassia bark oil china
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
iso
eugenyl acetate
FL/FR
ginger root absolute
FL/FR
methyl isoeugenol
FL/FR
nutmeg oil
FL/FR
black
pepper oil
FL/FR
3-
phenyl propyl alcohol
FL/FR
pimenta acris leaf oil
FL/FR
sweet
vanilla oleoresin bourbon
FL/FR
tea
tea leaf absolute
FL/FR
tropical
alpha-
amyl cinnamaldehyde
FL/FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
iso
amyl decanoate
FL/FR
decanal (aldehyde C-10)
FL/FR
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
mimosa absolute france
FL/FR
nonanol
FL/FR
woody
ambrette seed absolute
FL/FR
ambroxan
FL/FR
amyris wood oil
FL/FR
iso
bornyl acetate
FL/FR
frankincense oil
FL/FR
guaiacwood oil
FL/FR
beta-
ionone
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
iso
pulegyl acetate
FL/FR
sandalwood oil
FL/FR
sandalwood oil CO2 extract
FL/FR
spruce needle oil canada
FL/FR
vetiver oil haiti
FL/FR
 
Potential Uses:
FRacacia
FRaldehydic
FRallspice
 alpine bouquet
FRamber
FRambreine
FRamyris
FRanimal
FRazalea
FRbalsam
FRbayberry
FRbeeswax absolute replacer
 burberry
FRcabreuva wood
FRcalamus oil replacer
FRcassia
 cassia blossom
FRcedar forest
FRchampaca
FRchristmas
FRchypre
FRcinnamon
 clean
 cloth clean cloths
FRcoronilla
FRcountry meadow
FL/FRcroton eluteria bark
FRcyclamen
FRdaffodil
 dahlia
FRdaisy
FRdaphne
 diffusion
FRdillenia
FRdogwood
 dusty
FRelder flower
 enhancer
FRevergreen
FRfern
FRfetes
FRfig
FRfloral
 flouve blossom
 foliage
FRforest
FRfrangipani plumeria
FRfresh outdoors
FRgardenia
FRginger white ginger
FL/FRguaiacwood
FRhay new mown hay
FRheather
FRherbal
 hugonia
FRincense
 intensifier
FRiris blossom
FRivy
FRlavender
FRleather
FRlily
FRlily of the valley
FRlinden flower
 liverwort
FRlotus
FRmagnolia
FRmango flower
FRmoss
FRmusk
FRmyrrh
 new car
 ocean sea
FRopoponax
FRoriental
FRpassion blossom
FRpatchouli
FRpeach blossom
FLpear prickly pear
 petal white petal
FRpetunia
FRphlox
FRpinion
 plum blossom
 poppy
FRpowder
 privet blossom
FRreseda
FRrhubarb
FRrose
FRrose d'orient
FRrose moss rose
FRrose white rose
FRsandalwood
FRspice
FRspring rain
FRsweet grass
FRtobacco
FRtonka bean
FRtulip
FL/FRvalerian
FRvanilla
FRwoodruff
FRwoody
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 cervolide (Givaudan)
2,7-dioxacycloheptadecan-1-one
1,6-dioxacycloheptadecan-17-one
1,6-dioxacycloheptadecan-7-one
12-oxahexadecan-16-olide
12-oxahexadecanolide
12-oxa-1,16-hexadecanolide
 hibiscolide
16-hydroxy-12-oxahexadecanoic acid omega-lactone
11-(4-hydroxybutoxy) undecanoic acid omicron-lactone
 musk 174
 musk 781 (IFF)
 musk decanolide
 undecanoic acid, 11-(4-hydroxybutoxy)-, .omicron.-lactone
 undecanoic acid, 11-(4-hydroxybutoxy)-, omicron-lactone
 
 
Notes:
None found
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