delta-elemene
(1S,2R)-(-)-2-isopropenyl-1-vinyl-p-menth-3-ene
 
Notes:
None found
Synonyms   Articles   Notes   Search
(3S,4R)-4-ethenyl-4-methyl-1-propan-2-yl-3-prop-1-en-2-ylcyclohexene (Click)
CAS Number: 20307-84-0Picture of molecule
CoE Number: 10996
XlogP3-AA: 5.30 (est)
Molecular Weight: 204.35628000
Formula: C15 H24
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: CASrn in Register refers to the (3R,4R)-isomer.
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Flavis Number: 01.039 (Old)
DG SANTE Food Flavourings: 01.039  delta-elemene
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.85600 to 0.86200 @  25.00 °C.
Pounds per Gallon - (est).: 7.123 to  7.173
Refractive Index: 1.48000 to 1.48600 @  20.00 °C.
Boiling Point: 254.00 to  255.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 107.00 °C. @ 10.00 mm Hg
Vapor Pressure: 0.028000 mm/Hg @ 25.00 °C. (est)
Flash Point: 211.00 °F. TCC ( 99.50 °C. ) (est)
logP (o/w): 6.446 (est)
Soluble in:
 water, 0.01368 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: herbal
Odor Strength: medium
 sweet  herbal  lavender  woody  
Odor Description:
at 100.00 %. 
sweet herbal woody
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for delta-elemene usage levels up to:
  3.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3900 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 7.0000035.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 5.0000025.00000
Edible ices, including sherbet and sorbet (03.0): 10.0000050.00000
Processed fruit (04.1): 7.0000035.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 10.0000050.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 4.0000025.00000
Bakery wares (07.0): 10.0000050.00000
Meat and meat products, including poultry and game (08.0): 2.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.0000010.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.0000025.00000
Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 5.0000025.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
Ready-to-eat savouries (15.0): 20.00000100.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 25, (FGE.25)[1] - Aliphatic and aromatic hydrocarbons from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 78 (FGE.78)[1] - Consideration of Aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25 - Scientific Opinion of the Panel on Food Additives,Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 25Rev1: Aliphatic and aromatic hydrocarbons from chemical group 31
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 78, Revision 1 (FGE.78Rev1): Consideration of aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25Rev2
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 25, Revision 2 (FGE.25Rev2): Aliphatic and aromatic hydrocarbons from chemical group 31
View page or View pdf
Scientific opinion on Flavouring Group Evaluation 25, Revision 3 (FGE.25Rev3): Aliphatic hydrocarbons from chemical group 31
View page or View pdf
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 12004383
National Institute of Allergy and Infectious Diseases: Data
 (3S,4R)-4-ethenyl-4-methyl-1-propan-2-yl-3-prop-1-en-2-ylcyclohexene
Chemidplus: 0020307840
Synonyms   Articles   Notes   Search   Top
References:
 (3S,4R)-4-ethenyl-4-methyl-1-propan-2-yl-3-prop-1-en-2-ylcyclohexene
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 12004383
Pubchem (sid): 135045775
Flavornet: 20307-84-0
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FooDB: FDB006578
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 angelica root oil @ 0.42%
Data  GC  Search Trop  Picture
 anise seed
Search Trop  Picture
 baccharis coridifolia oil argentina @ 0.10%
Data  GC  Search Trop  Picture
 basil oil CO2 sweet @ trace%
Data  GC  Search Trop  Picture
 basil oil sweet @ trace%
Data  GC  Search Trop  Picture
 bergamot oil @ 0.000-0.007%
Data  GC  Search Trop  Picture
 boronia absolute @ 0.01%
Data  GC  Search Trop  Picture
 cajuput oil vietnam @ trace%
Data  GC  Search Trop  Picture
 calamus leaf oil @ 0.21%
Data  GC  Search Trop  Picture
 calamus root oil mongolia @ 0.50%
Data  GC  Search Trop  Picture
 cananga leaf oil @ 1.1%
Data  GC  Search Trop  Picture
 cassis bud oil @ trace-0.24%
Data  GC  Search Trop  Picture
 cedrela wood oil @ 0.44%
Data  GC  Search Trop  Picture
 chamomile oil morocco @ 0.70%
Data  GC  Search Trop  Picture
 citronella oil ceylon @ 0.03%
Data  GC  Search Trop  Picture
 citronella oil china @ 0.01%
Data  GC  Search Trop  Picture
 citronella oil java @ 0.01%
Data  GC  Search Trop  Picture
 clary sage oil spain @ trace%
Data  GC  Search Trop  Picture
 croton cajucara benth. leaf oil brazil @ 0.30%
Data  GC  Search Trop  Picture
 croton flavens l. (welensali) leaf oil curacao @ 0.30%
Data  GC  Search Trop  Picture
 cubeb oil @ 0.10%
Data  GC  Search Trop  Picture
 curcuma amada roxb. rhizome oil india @ 0.20%
Data  GC  Search Trop  Picture
 curry wood leaf oil australia @ 0.40%
Data  GC  Search Trop  Picture
 ginger root oil china @ 0.10%
Data  GC  Search Trop  Picture
 ginger root oil CO2 extract australia @ 0.23%
Data  GC  Search Trop  Picture
 guava leaf oil cuba @ trace%
Data  GC  Search Trop  Picture
 guava oil
Search Trop  Picture
 jambu flower oil brazil @ 0.30%
Data  GC  Search Trop  Picture
 kachur oil @ 0.20%
Data  GC  Search Trop  Picture
 lavender oil france @ trace%
Data  GC  Search Trop  Picture
 lime oil distilled mexico @ 0.06%
Data  GC  Search Trop  Picture
 lime oil distilled peru @ 0.05%
Data  GC  Search Trop  Picture
 lime oil expressed florida @ 0.1%
Data  GC  Search Trop  Picture
 mandarin fruit
Search Trop  Picture
 mandarin fruit juice - trace amount
Search  Picture
 mandarin oil uruguay @ 0.01%
Data  GC  Search Trop  Picture
 marjoram oil sweet cuba @ trace%
Data  GC  Search Trop  Picture
 marjoram oil sweet cyprus @ trace-0.20%
Data  GC  Search Trop  Picture
 marjoram oil sweet turkey @ 0.03-0.04%
Data  GC  Search Trop  Picture
 marsypianthes chamaedrys (vahl) kuntze oil brazil @ 2.50%
Data  GC  Search Trop  Picture
 mikan peel oil @ trace%
Data  GC  Search Trop  Picture
 mikania cordata (burm. f.) b.l. robinson var. cordata leaf oil france @ 0.50%
Data  GC  Search Trop  Picture
 ocimum gratissimum l. oil brazil @ 0.17%
Data  GC  Search Trop  Picture
 orange peel oil bitter china @ 0.01%
Data  GC  Search Trop  Picture
 patchouli oil china @ 0.04%
Data  GC  Search Trop  Picture
 pepper black pepper fruit
Search Trop  Picture
 pepper black pepper fruit oil
Search Trop  Picture
 pepper oil black india @ 0.10%
Data  GC  Search Trop  Picture
 phlomis fruticosa l. flower oil greece @ 0.20%
Data  GC  Search Trop  Picture
 phoebe oil brazil @ 0.06%
Data  GC  Search Trop  Picture
 piper cernum vell. var. cernum yuncker leaf oil brazil @ 0.20%
Data  GC  Search Trop  Picture
 polyalthia australis (benth.) jessup leaf oil australia @ 0.40%
Data  GC  Search Trop  Picture
 ravintsara leaf oil @ 0.55%%
Data  GC  Search  Picture
 salvia atropatana bunge oil iran @ 1.10%
Data  GC  Search Trop  Picture
 savin oil @ 0.36%
Data  GC  Search Trop  Picture
 sideritis montana l. oil bulgaria @ 5.60%
Data  GC  Search Trop  Picture
 sideritis scardica l. oil bulgaria @ 0.80%
Data  GC  Search Trop  Picture
 sideritis syriaca l. oil bulgaria @ 1.50%
Data  GC  Search Trop  Picture
 tagete oil CO2 extract @ 3.00%
Data  GC  Search Trop  Picture
 valerian root oil @ 0.2-2.9%
Data  GC  Search Trop  Picture
 valerian root oil CO2 extract china @ 0.08%
Data  GC  Search Trop  Picture
 vassoura oil @ 0.40%
Data  GC  Search Trop  Picture
 yarrow oil @ 0.10%
Data  GC  Search Trop  Picture
 ylang ylang oil CO2 extract @ 0.02%
Data  GC  Search Trop  Picture
 yuzu peel oil c.p. @ 0.01-0.02%
Data  GC  Search Trop  Picture
 yuzu peel oil CO2 extract @ 0.01-0.02%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
1,3,6-elematriene
(3S,4R)-4-ethenyl-4-methyl-1-propan-2-yl-3-prop-1-en-2-ylcyclohexene
(3R-(E))-4-ethenyl-4-methyl-3-(1-methyl ethenyl)-1-(1-methyl ethyl) cyclohexene
(3R-trans)-4-ethenyl-4-methyl-3-(1-methyl ethenyl)-1-(1-methyl ethyl) cyclohexene
(1S,2R)-(-)-2-isopropenyl-1-vinyl-p-menth-3-ene
(1S,2R)-(-)-2-isopropenyl-1-vinyl-para-menth-3-ene
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Chemical compositions and antimicrobial activity of the essential oils of Hornstedtia havilandii (Zingiberaceae).
PubMed: Combined analysis of the root bark oil of Cleistopholis glauca by chromatographic and spectroscopic techniques.
PubMed: Chemical composition of essential oils from the leaves and stem barks of Vietnamese species of Polyalthia harmandiiPolyalthia jucunda and Polyalthia thorelii.
PubMed: Constituents of essential oils from the leaves, stem barks and resins of Canarium parvum Leen., and Canarium tramdenanum Dai et Yakovl. (Burseracea) grown in Vietnam.
PubMed: Comparative analysis of the essential oil composition of Murraya paniculata and M. exotica.
PubMed: Essential oils composition of croton species from the Amazon.
PubMed: Quantitative Analysis and Discrimination of Steamed and Non-Steamed Rhizomes of Curcuma wenyujin by GC-MS and HPLC.
PubMed: Chemical composition and antimicrobial activity of three essential oils from Curcuma wenyujin.
PubMed: Chemical composition and anti-Trypanosoma cruzi activity of essential oils obtained from leaves of Xylopia frutescens and X. laevigata (Annonaceae).
PubMed: Analysis of Cleistopholis patens leaf and trunk bark oils using combined GC- flame ionisation detection, GC-retention index, GC-MS and (13) C-NMR.
PubMed: Essential oils from five species of Annonaceae from Vietnam.
PubMed: Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations.
PubMed: Antimicrobial activity of selected essential oils against cariogenic bacteria.
PubMed: Antifungal and antibacterial activity of the essential oil of Chamaecyparis lawsoniana from Spain.
PubMed: Study on the volatile oil contents of Annona glabra L., Annona squamosa L., Annona muricata L. and Annona reticulata L., from Vietnam.
PubMed: Chemical composition of the essential oils of Centaurea formanekii and C. orphanidea ssp. thessala, growing wild in Greece.
PubMed: Chemical composition and biological activities of the essential oils from Duguetia lanceolata St. Hil. barks.
PubMed: Furanodiene induces endoplasmic reticulum stress and presents antiproliferative activities in lung cancer cells.
PubMed: Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review.
PubMed: Differences in the volatile compositions of ginseng species (Panax sp.).
PubMed: Composition and antioxidant capacity of the essential oil of leaves of Vitex megapotamica (Sprengel) Moldenke.
PubMed: Natural product studies of U.S. endangered plants: volatile components of Lindera melissifolia (Lauraceae) repel mosquitoes and ticks.
PubMed: Volatiles from Magnolia grandiflora flowers: comparative analysis by simultaneous distillation-extraction and solid phase microextraction.
PubMed: The leaf essential oils of five Vietnamese Desmos species (Annonaceae).
PubMed: Chemical and biological analyses of the essential oils and main constituents of Piper species.
PubMed: Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by δ-elemene.
PubMed: Fractionation of volatile constituents from curcuma rhizome by preparative gas chromatography.
PubMed: California Lomatiums, Part X. Comparison of composition of the hydrodistilled oils from two subspecies of Lomatium mohavense.
PubMed: Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed: B-cell lymphoma-2 over-expression protects δ-elemene-induced apoptosis in human lung carcinoma mucoepidermoid cells via a nuclear factor kappa B-related pathway.
PubMed: Lysosomal membrane permeabilization contributes to elemene emulsion-induced apoptosis in A549 cells.
PubMed: The compositions of volatiles and aroma-active compounds in dried omija fruits (Schisandra chinensis Baillon) according to the cultivation areas.
PubMed: Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis.
PubMed: Comparative volatile oil composition of four Ocimum species from northern India.
PubMed: Chemical composition and antibacterial activity of the essential oil of Drimys granadensis L.f. leaves from Colombia.
PubMed: Essential oil composition of Vismia macrophylla leaves (Guttiferae).
PubMed: Caryophyllene oxide-rich essential oils of Lithuanian Artemisia campestris ssp. campestris and their toxicity.
PubMed: Phytochemical investigation of Verbesina turbacensis Kunth: trypanosome cysteine protease inhibition by (-)-bornyl esters.
PubMed: Essential oils from two Lantana species with antimycobacterial activity.
PubMed: Cell apoptosis induced by delta-elemene in colorectal adenocarcinoma cells via a mitochondrial-mediated pathway.
PubMed: Essential oil composition from two species of Piperaceae family grown in Colombia.
PubMed: Antiatherogenic activity of Dendropanax morbifera essential oil in rats.
PubMed: Seasonal variation and bioactivity in the leaf oil of Liriodendron tulipifera growing in Huntsville, Alabama.
PubMed: GC-MS analysis and antimicrobial activity of essential oil of Stachys cretica subsp. smyrnaea.
PubMed: Essential oil compositions of three Lantana species from Monteverde, Costa Rica.
PubMed: Antiulcerogenic and anti-inflammatory activities of the essential oil from Pterodon emarginatus seeds.
PubMed: Synthesis and in vitro anti-proliferative activity of beta-elemene monosubstituted derivatives in HeLa cells mediated through arrest of cell cycle at the G1 phase.
PubMed: Chemical constituents and larvicidal property of the essential oil of Blumea mollis (D. Don) Merr. against Culex quinquefasciatus.
PubMed: Antiectoparasitic activity of the gum resin, gum haggar, from the East African plant, Commiphora holtziana.
PubMed: Bioactivity and chemical composition of the leaf essential oils of Zanthoxylum rhoifolium and Zanthoxylum setulosum from Monteverde, Costa Rica.
PubMed: Volatile components from the roots of Solanum pseudocapsicum.
PubMed: [Extraction and identification of volatile constituents in the flowers of Aglaia odorata Lour].
PubMed: The volatile constituents analysis of Eremostachys macrophylla Montbr. & Auch. from Iran.
PubMed: Effect of delta-elemene on Hela cell lines by apoptosis induction.
PubMed: Optimization of GC-MS conditions based on resolution and stability of analytes for simultaneous determination of nine sesquiterpenoids in three species of Curcuma rhizomes.
PubMed: [Radiosensitization of beta-elemene on VX2 carcinoma transplanted on kidney in rabbits in vivo].
PubMed: [Analysis of volatile constituents in leaves of three cypress species by gas chromatography/mass spectrometry].
PubMed: Determination of Teucrium chamaedrys volatiles by using direct thermal desorption-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
PubMed: Antioxidant and biocidal activities of Carum nigrum (seed) essential oil, oleoresin, and their selected components.
PubMed: Headspace solid-phase microextraction-gas chromatography--mass spectrometry analysis of the volatile compounds of Evodia species fruits.
PubMed: Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry.
PubMed: Analysis of leaf surface sesquiterpenes in potato varieties.
PubMed: Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection.
PubMed: Application of multidimensional gas chromatography to the enantioselective characterisation of the essential oil of Eupatorium buniifolium Hooker et Arnott.
PubMed: Isogermacrene A, a proposed intermediate in sesquiterpene biosynthesis.
PubMed: Chemical composition and in vitro antimicrobial activities of the essential oils from endemic Psiadia species growing in mauritius.
PubMed: Volatile constituents and key odorants in leaves, buds, flowers, and fruits of Laurus nobilis L.
PubMed: Interspecific variation in terpenoid composition of defensive secretions of European Reticulitermes termites.
PubMed: Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction-gas chromatography, solid-phase microextraction-gas chromatography-mass spectrometry and olfactometry.
PubMed: Germacrene A is a product of the aristolochene synthase-mediated conversion of farnesylpyrophosphate to aristolochene.
PubMed: [Clinical study on treatment of 40 cases of malignant brain tumor by elemene emulsion injection].
PubMed: Chemical variability of the volatile metabolites from the Caribbean corals of the genus Gorgonia.
PubMed: (+)-Germacrene A biosynthesis . The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
PubMed: Volatile constituents of Origanum vulgare ssp. viride (syn. O. heracleoticum) from Iran.
PubMed: [Essential oil components in leaves and stems of Piper bisasperatum (Piperaceae)].
PubMed: Production of volatile sesquiterpenes by Fusarium sambucinum strains with different abilities to synthesize trichothecenes.
PubMed: Germacrene-C, precursor of delta-elemene.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2017 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy