EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

amber naphthofuran
1,5,5,9-tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane

Sponsors

Fragrance Demo Formulas
Name:3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
CAS Number: 3738-00-9Picture of molecule3D/inchi
Other:193980-58-4
ECHA EINECS - REACH Pre-Reg:223-118-6
Nikkaji Web:J205.641K
CoE Number:10514
XlogP3-AA:4.70 (est)
Molecular Weight:236.39836000
Formula:C16 H28 O
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
Mixture of diastereoisomers (EFFA, 2010a).
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:1240 1,5,5,9-tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane
FLAVIS Number:13.072 (Old)
DG SANTE Food Flavourings:13.072 1,5,5,9-tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane
FEMA Number:3471 1,5,5,9-tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Appearance:colorless to pale yellow liquid to solid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 75.00 to 85.00 °C. @ 760.00 mm Hg
Boiling Point: 102.00 to 106.00 °C. @ 25.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.009000 mm/Hg @ 25.00 °C. (est)
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 5.256 (est)
Soluble in:
 alcohol
 water, slightly
 water, 2.436 mg/L @ 25 °C (est)
Stability:
 APC: traces - 1%
 candle: traces - 1%
 detergent: traces - 1%
 fine fragrances: 0.5 - 5%
 shampoo: traces - 0.5%
 shower gel: traces - 0.5%
 soap: traces - 0.5%
 softener: traces - 1%
Similar Items:note
(-)-dodecahydrotetramethyl naphthofuran
dodecahydrotetramethyl epoxynaphthoxepin
dodecahydrocyclododecafuran
 
Organoleptic Properties:
Odor Type: amber
Odor Strength:high ,
recommend smelling in a 10.00 % solution or less
Substantivity: > 400 hour(s) at 10.00 % in dipropylene glycol
dry woody amber ambergris musk sweet
Odor Description:at 10.00 % in dipropylene glycol. dry woody amber ambergris musk sweet
Luebke, William tgsc, (1986)
Odor sample from: Firmenich Inc.
Flavor Type: amber
amber woody old wood tobacco powdery dry ambergris animal
Taste Description: amber old wood tobacco powdery dry ambergris animal
Odor and/or flavor descriptions from others (if found).
Firmenich
AMBROX® DL
Odor Description:An elegant amber note with a rich woody character
This ingredient provides warmth, richness and elegance to all areas of perfumery from sheer florals to modern orientals. Due to its power, best effects can be achieved at lower dosages, however, higher levels are often used to provide performance and substantivity.
Firmenich
CETALOX®
Odor Description:An extremely powerful and elegant amber note
CETALOX® gives rich, elegant effects to all areas of perfumery from sheer florals to modern orientals. Enhanced richness, warmth and depth can be achieved at lower dosages while, at higher levels, it provides exceptional substantivity and performance.
Firmenich
CETALOX® LAEVO
Odor Description:An extremely powerful and elegant amber note, more ambery and sharper than CETALOX«
CETALOX® LAEVO gives rich, elegant effects to all areas of perfumery, from sheer florals to modern orientals. It is highly diffusive and brings a unique ambergris effect from top note to dry down.
IFF
Ambermor DL
Odor Description:Strong amber with dry and woody notes
IFF
Cetalor
Odor Description:One of the finest ambergris notes, powerful amber, woody odor, which gives rich, elegant effects to all kinds of perfumery
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Associate Allied Chemicals
Synambran
About
Azelis UK
AMBROX® DL
Services
Azelis UK
CETALOX
BOC Sciences
For experimental / research use only.
AMBROX DL 95%
Ernesto Ventós
AMBROTECH KAO
Ernesto Ventós
AMBROX DL FIRMENICH 909120
Odor: AMBERGRIS, WOODY
Ernesto Ventós
CETALOX FIRMENICH 922560
Odor: ELEGANT NOTE OF AMBAR
Firmenich
AMBROX® DL
Odor: An elegant amber note with a rich woody character
Use: This ingredient provides warmth, richness and elegance to all areas of perfumery from sheer florals to modern orientals. Due to its power, best effects can be achieved at lower dosages, however, higher levels are often used to provide performance and substantivity.
Firmenich
CETALOX® LAEVO
Firmenich
CETALOX®
Odor: An extremely powerful and elegant amber note
Use: CETALOX® gives rich, elegant effects to all areas of perfumery from sheer florals to modern orientals. Enhanced richness, warmth and depth can be achieved at lower dosages while, at higher levels, it provides exceptional substantivity and performance.
IFF
Ambermor DL
Odor: Strong amber with dry and woody notes
IFF
Cetalor
Odor: One of the finest ambergris notes, powerful amber, woody odor, which gives rich, elegant effects to all kinds of perfumery
Indukern F&F
AMBEROX DL
Odor: AMBER, WOODY
Indukern F&F
AMBROTECH
Odor: WOODY, SWEET
Liaison Carbone
CETALOX® 922560
Lluch Essence
AMBROX DL
Odor: WOODY, AMBER LIKE
Lluch Essence
CETALOX 96%
Moellhausen
AMBROX DL
Odor: strong amber-note, dry and woody notes
Penta International
AMBROX DL
Penta International
DODECAHYDRO-3a,6,6,9a-TETRAMETHYLNAPHTO-(2,1-b)-FURAN, Kosher
Perfumery Laboratory
Ambrox® DL 20% in Firmenich DPG (AMBROX® DL 20% DPG Firmenich)
Odor: Sweet, amber, musky aroma. It is amber naphthofuran
Perfumery Laboratory
TSETALOKS ™ F (CETALOX ™ F)
Odor: beautiful natural aroma components whale ambergris. Sweet, with hints of fresh wood. It has a long diffusion
The Perfumers Apprentice
Ambrox DL
Odor: dry woody amber ambergris musk sweet
The Perfumers Apprentice
Cetalox (F) (crystals)
Vigon International
Ambrox DL
Odor: AMBER, WOODY
Vigon International
Ambrox Super
Vigon International
Cetalox
Odor: AMBER.
 
Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for amber naphthofuran usage levels up to:
  5.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 1.20 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.10 (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 9
 average usual ppmaverage maximum ppm
baked goods: -0.01000
beverages(nonalcoholic): -0.01000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: -0.01000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.01000
fruit ices: -0.01000
gelatins / puddings: -0.01000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 33 (FGE.33)[1] - Six Tetrahydrofuran Derivatives from Chemical Groups 13, 14, 16 and 26 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010)
View page or View pdf

EPI System: View
EPA Substance Registry Services (TSCA):3738-00-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :107166
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
Chemidplus:0003738009
 
References:
Leffingwell:Chirality or Article
 3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:3738-00-9
Pubchem (cid):107166
Pubchem (sid):135063926
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2932.19.0000
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
For Odor
No odor group found for these
amber romance fragrance
FR
(Z)-iso
ambrettolide
FR
aldehydic
aldehydic
dodecanal (aldehyde C-12 lauric)
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
amber
(Z)-
abienol
FL/FR
acetoxymethyl isolongifolene
FR
amber acetate
FR
amber butanol
FR
amber cyclohexanol
FR
amber decane
FR
amber furan
FR
amber oxepin
FR
amber spirolene
FR
ambergris naphthol
FR
ambergris specialty
FR
ambrein
FR
ambrette seed absolute
FL/FR
ambrette seed oil CO2 extract
FL/FR
ambrette seed oil replacer
FR
alpha-
ambrinol
FL/FR
ambrinol
FR
ambroxan
FL/FR
ambroxide
FL/FR
angelica root oil
FL/FR
cistus ladaniferus absolute resin
FL/FR
cistus ladaniferus resinoid
FR
formoxymethyl isolongifolene
FR
(cis+trans)-6,6a,7,8,9,9a-
hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
FR
hydroxymethyl isolongifolene 50% in dpg
FR
labdanum absolute
FL/FR
labdanum oil
FL/FR
muscomer
FR
animal
animal carbolactone
FR
costus valerolactone
FR
indole
FL/FR
2-
methyl-4-(camphenyl-8) cyclohexanone
FR
musk indenofuran
FR
anisic
ambrette seed oil
FL/FR
balsamic
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
laevo-
borneol
FL/FR
brachyleana hutchinsii wood oil
FR
juniper berry concrete
FR
opoponax absolute (commiphora erythraea var. glabrescens engle)
FL/FR
opoponax resinoid (commiphora erythraea var. glabrescens engle)
FR
valerian rhizome absolute
FL/FR
berry
raspberry ketone
FL/FR
caramellic
ethyl maltol
FL/FR
immortelle absolute
FL/FR
maltol
FL/FR
citrus
bitter
orange peel oil
FL/FR
bitter
orange peel oil brazil
FL/FR
bitter
orange peel oil italy
FL/FR
coconut
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
gamma-
octalactone
FL/FR
earthy
(Z)-
linalool oxide (furanoid)
FL/FR
fatty
decanol
FL/FR
floral
acetophenone
FL/FR
amyl benzoate
FL/FR
iso
amyl salicylate
FL/FR
angel wings fragrance
FR
bois de rose oil brazil
FL/FR
boronia butenal
FR
iso
butyl salicylate
FL/FR
cyclamen aldehyde
FL/FR
dihydrojasmone
FL/FR
floral pyranol
FR
heliotropyl acetone
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
beta-
ionone
FL/FR
lilyall
FR
laevo-
linalool
FL/FR
methyl dihydrojasmonate
FL/FR
N-
methyl ionone
FR
alpha-iso
methyl ionone (50% min.)
FL/FR
methyl ionyl acetate
FL/FR
2-
methyl naphthalene
FL/FR
nerolidol
FL/FR
nonanol
FL/FR
ocean propanal
FL/FR
bitter
orangeflower concrete morocco
FR
phenethyl phenyl acetate
FL/FR
fruity
gamma-
decalactone
FL/FR
(R)-gamma-
dodecalactone
FL/FR
menthyl isovalerate
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
valeriana officinalis root extract
FL/FR
green
diphenyl oxide
FL/FR
galbanum oil
FL/FR
iso
green methanoindene
FR
methyl cyclocitrone (IFF)
FR
methyl heptine carbonate
FL/FR
(E,Z)-2,6-
nonadien-1-ol
FL/FR
rose leaf absolute (rosa centifolia)
FL/FR
violet leaf absolute
FL/FR
hay
beeswax absolute
FL/FR
herbal
(+)-alpha-
campholenic aldehyde
FL/FR
daucus carota fruit oil
FL/FR
delta-
elemene
FL/FR
herbal carene
FR
tea leaf absolute
FL/FR
melon
melon heptenal
FL/FR
(Z)-6-
nonenal
FL/FR
watermelon ketone
FR
mentholic
iso
pulegyl acetate
FL/FR
mossy
oriental specialty
FR
veramoss (IFF)
FR
musk
acetyl ethyl tetramethyl tetralin replacer
FR
dehydro beta-linalool
FL/FR
musk amberol
FR
musk decanolide
FR
musk dimethyl indane
FL/FR
musk indane
FR
musk indanone
FR
musk lactone
FR
musk methyl ketone
FR
6,7,8,9-
tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
FR
musty
ketoiso
phorone
FL/FR
opoponax
opoponax resinoid replacer
FR
spicy
cassia bark oil china
FL/FR
black
currant bud absolute
FL/FR
2,5-
dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate
FR
iso
eugenyl acetate
FL/FR
ginger root absolute
FL/FR
grains of paradise oil
FL/FR
methyl heptadienone
FL/FR
terpenic
angelica seed oil
FL/FR
frankincense oil
FL/FR
tonka
tonka bean absolute
FR
waxy
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
woody
acetyl cedrene
FR
agarwood oil (aetoxylon sympetalum)
FR
amber carbinol
FR
amber decatriene
FR
amber dioxane
FR
amber dodecane
FR
amber formate
FR
ambrene acetal
FR
cabreuva wood oil
FR
beta-
caryophyllene oxide
FL/FR
atlas
cedarwood absolute
FR
atlas
cedarwood oil
FR
cedrela wood oil
FR
alpha-
cedrene epoxide
FR
cedrenyl acetate
FR
cedryl acetate
FL/FR
cedryl methyl ether
FR
cistus ladaniferus gum
FR
cistus twig/leaf absolute
FR
cistus twig/leaf oil
FL/FR
guaiacwood oil
FL/FR
guaiacwood oil 20% in gurjun balsam oil
FR
gurjun balsam oil
FR
hinoki root oil
FR
homalomena rubescens root oil
FR
hydroxyambran
FR
labdanum concrete
FR
labdanum ethanone
FR
iso
longifolene epoxide
FR
iso
longifolene ketone
FR
para-
menth-3-en-1-ol
FL/FR
2-
methoxy-4-vinyl phenol
FL/FR
methyl 2,6,10-trimethyl cyclododeca-2,5,9-trienyl ketone
FR
methyl cedryl ketone
FL/FR
delta-
methyl ionone
FL/FR
methyl vetivate
FR
patchouli ethanone
FR
patchouli oil
FL/FR
sandal pentenol
FL/FR
sandalwood oil CO2 extract
FL/FR
sandalwood oil west australia (santalum spicata)
FR
santall
FR
sclareolide
FL/FR
spikenard oil CO2 extract
FL/FR
spruce needle oil canada
FL/FR
timber propanol
FR
tobacarol (IFF)
FR
tobacco nonene
FR
woody acetate
FR
woody cyclohexanone
FR
woody dioxolane
FR
woody dodecane
FR
woody ether
FR
woody nonane (ethoxy)
FR
For Flavor
No flavor group found for these
ambrette seed oil
FL/FR
ambroxide
FL/FR
amyl benzoate
FL/FR
cistus twig/leaf oil
FL/FR
dehydro beta-linalool
FL/FR
(R)-gamma-
dodecalactone
FL/FR
delta-
elemene
FL/FR
grains of paradise oil
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
para-
menth-3-en-1-ol
FL/FR
delta-
methyl ionone
FL/FR
sandal pentenol
FL/FR
spikenard oil CO2 extract
FL/FR
amber
amber
ambrette seed oil CO2 extract
FL/FR
alpha-
ambrinol
FL/FR
angelica seed oil
FL/FR
cistus ladaniferus absolute resin
FL/FR
labdanum absolute
FL/FR
labdanum oil
FL/FR
animal
indole
FL/FR
apple
(E,Z)-2,6-
nonadien-1-ol
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
opoponax absolute (commiphora erythraea var. glabrescens engle)
FL/FR
berry
heliotropyl acetone
FL/FR
raspberry ketone
FL/FR
brown
beeswax absolute
FL/FR
camphoreous
laevo-
borneol
FL/FR
caramellic
caramel furanone
FL
ethyl maltol
FL/FR
maltol
FL/FR
citrus
laevo-
linalool
FL/FR
bitter
orange peel oil
FL/FR
bitter
orange peel oil italy
FL/FR
ketoiso
phorone
FL/FR
coconut
gamma-
nonalactone (aldehyde C-18 (so-called))
FL/FR
cooling
iso
butyl salicylate
FL/FR
creamy
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
fatty
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
bois de rose oil brazil
FL/FR
dihydrojasmone
FL/FR
methyl dihydrojasmonate
FL/FR
alpha-iso
methyl ionone (50% min.)
FL/FR
ocean propanal
FL/FR
fruity
gamma-
decalactone
FL/FR
menthyl isovalerate
FL/FR
bitter
orange peel oil brazil
FL/FR
valerian rhizome absolute
FL/FR
valeriana officinalis root extract
FL/FR
green
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
(+)-alpha-
campholenic aldehyde
FL/FR
cyclamen aldehyde
FL/FR
diphenyl oxide
FL/FR
galbanum oil
FL/FR
immortelle absolute
FL/FR
melon heptenal
FL/FR
methyl heptadienone
FL/FR
methyl heptine carbonate
FL/FR
nerolidol
FL/FR
(Z)-6-
nonenal
FL/FR
iso
phorone
FL
rose leaf absolute (rosa centifolia)
FL/FR
violet leaf absolute
FL/FR
herbal
daucus carota fruit oil
FL/FR
honey
phenethyl phenyl acetate
FL/FR
lactonic
gamma-
octalactone
FL/FR
musk
musk dimethyl indane
FL/FR
oily
2-
methyl naphthalene
FL/FR
powdery
acetophenone
FL/FR
smoky
2-
methoxy-4-vinyl phenol
FL/FR
dextro-
xylose
FL
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
1-
dodecanol
FL/FR
spicy
cassia bark oil china
FL/FR
black
currant bud absolute
FL/FR
iso
eugenyl acetate
FL/FR
ginger root absolute
FL/FR
tea
tea leaf absolute
FL/FR
waxy
decanol
FL/FR
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
nonanol
FL/FR
woody
(Z)-
abienol
FL/FR
ambrette seed absolute
FL/FR
ambroxan
FL/FR
amyris wood oil
FL/FR
beta-
caryophyllene oxide
FL/FR
cedryl acetate
FL/FR
frankincense oil
FL/FR
guaiacwood oil
FL/FR
beta-
ionone
FL/FR
methyl cedryl ketone
FL/FR
methyl ionyl acetate
FL/FR
patchouli oil
FL/FR
iso
pulegyl acetate
FL/FR
sandalwood oil CO2 extract
FL/FR
sclareolide
FL/FR
spruce needle oil canada
FL/FR
 
Potential Uses:
FRagate
FRamber
FRambergris
FRambreine
FRambrette oil replacer
FRanimal
FRbaby powder
FRbalsam
FRbay rum
FRbayberry
FRblackberry
FRblue grass
FRblueberry
FRbouquet
FRcabreuva wood
FRcastoreum
FRcedar forest
FRchristmas
 cigar box
 cloth clean cloths
FRcoronilla
FRdeertongue absolute replacer
 dry
FRearth
 fantasy blends
FRfern
FRfir balsam
FRfloral
FL/FRguaiacwood
FRhabuba
FRhay new mown hay
FRheather
FRherbal
FRhollyberry
FRincense
FRjuniper berry
FRlabdanum
FRleather
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 ocean sea
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FLtea
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 tweed
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FRwoody
 
Occurrence (nature, food, other):note
 found in nature
 salvia sclarea oil greece @ 0.10%
Data GC Search Trop Picture
 
Synonyms:
 amber naphthofuran
 ambermor DL (IFF)
 amborl DL
 ambrox DL (Firmenich)
 ambrox super (Firmenich)
 cetalor (IFF)
 cetalox (Firmenich)
 cetalox laevo (Firmenich)
 dodecahydro-3a,6,6,9a-tetramethyl naphtho(2,1-beta)furan
 dodecahydro-3a,6,6,9a-tetramethylnaphtho(2,1-b)furan
 dodecahydro-3a,6,6,9a-tetramethylnaphto-(2,1-b)-furan
 dodecahydro-3a-,6,6,9a-tetramethyl(2,1beta)furan
 dodecahydrotetramethyl naphthofuran
 fixambrene
 naphtho(2,1-b)furan, dodecahydro-3a,6,6,9a-tetramethyl-
 naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-
 synambran
 tetramethyl dodecahydro-3a,6,6,9a-naphtho(2,1-b)furan
 tetramethyl perhydronaphthofurane
1,5,5,9-tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane
3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
1,6,10,10-tetramethyl-5-oxatricyclo[7.4.0.0<2,6>]tridecane
3a,6,6,9a-tetramethyl-dodecahydro-naphtho[2,1-b]furan
3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan
3a,6,6,9a-tetramethylperhydronaphtho[2,1-b]furan
 

Articles:

Info:Ambrox / Ambroxan
Google Patents:(+)-Ambrox, process for production thereof and use thereof
US Patents:8,222,200 - Organic compounds
PubMed:Toward a biosynthetic route to sclareol and amber odorants.
PubMed:A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate.
PubMed:Biotransformation of perfumery terpenoids, (-)-ambrox® by a fungal culture Macrophomina phaseolina and a plant cell suspension culture of Peganum harmala.
PubMed:Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.
PubMed:Communic acids: occurrence, properties and use as chirons for the synthesis of bioactive compounds.
PubMed:Isolation, chemical, and biotransformation routes of labdane-type diterpenes.
PubMed:Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products.
PubMed:Chiral decalins: preparation from oleanolic acid and application in the synthesis of (-)-9-epi-ambrox.
PubMed:Biotransformation of (-)-ambrox by cell suspension cultures of Actinidia deliciosa.
PubMed:Chiral proton donor reagents: tin tetrachloride--coordinated optically active binaphthol derivatives.
PubMed:Enantio- and diastereoselective stepwise cyclization of polyprenoids induced by chiral and achiral LBAs. A new entry to (-)-ambrox, (+)-podocarpa-8,11,13-triene diterpenoids, and (-)-tetracyclic polyprenoid of sedimentary origin.
PubMed:Oxidative metabolism of ambrox and sclareolide by Botrytis cinerea.
 
Notes:
Ambrox replacer.
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