potent bell pepper odourant; binds to cow olfactory mucosa homogenate.
  • Advanced Biotech
  • Apiscent Labs
    • Apiscent Labs, LLC
      Delivery of Quality
      Custom manufacturer and international supplier of fine ingredients.
      We believe inspired chemistry enriches lives. That's why our team is guided by a mission to provide fine ingredients to the worldwide pharmaceutical, flavor and fragrance markets with a primary focus on the manufacturing of value-added, research-based molecules. We're innovative problem solvers committed to excellence at every phase. Our work builds the foundation for our clients' continued success.
      Email: Info
      Email: Carl Sheeley
      Email: Customer Service
      Voice: +1 (414) 744 3993
      Fax: +1 (414) 744 7111
      2 METHOXY 3 ISOBUTYLPYRAZINE (2-Isobutyl-3-methoxypyrazine)
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
      Mr. Guo86-10-68418739
      10001 2-isobutyl-3-methoxypyrazine
  • DeLong Chemicals America
    • DeLong Chemicals America
      Custom Manufacturing
      Supplier of aroma chemicals, pharmaceutical and specialty chemical intermediates.
      DeLong Chemicals America, LLC is an extension of Shijiazhuang Lida Chemical Co, Ltd to North America, a leading supplier and manufacturer of aroma chemicals, serving the industries of food, tobacco and perfume, while also providing intermediates, custom synthesis and custom manufacturing for pharmaceutical and specialty chemical industries.
      US Email: Customer Service
      US Email: Sales
      US Voice: (203) 271-9017
      New products
      9870 2-Isobutyl-3-methoxypyrazine
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      Email: Information
      US Voice: 845-341-2100
      US Fax: 845-341-2121
      2-methoxy 3-isobutyl pyrazine
  • Frutarom
    • Frutarom Ltd
      Discover Our Passion
      Your preferred partner for flavour and fragrance success.
      At Frutarom, we take pride in our expertise and knowledge of Flavour & Fragrance Ingredients and our thorough understanding of the needs of Flavourists, Perfumers and Food Technologists. Working closely with our customers we have a strong track record of providing unique solutions to fulfil requirements.
      US Email: Info- USA
      Email: Info - UK
      Voice: +44 (0) 1429 863 222
      US Voice: +1 513 870 4900
      Products List: View
      I0930-0 2-ISOBUTYL-3(5/6)-METHOXYPYRAZINE ≥99.00% (sum of isomers), NI, Kosher
      Suggested Uses: Coffee, Galbanum, Vegetables
  • Hermitage Oils
    • Hermitage Oils
      Perfumery and Aromatherapy materials since 1979
      Hermitage Oils, the true home of essential oils!
      Hermitage Oils offers a selection of Absolutes, Essential Oils, Natural Isolates, Aroma Chemicals, CO2 Extracts, Ethanol Tinctures, and Extraits by Enfleurage.
      Email: Info
      Email: Sales
      The Vault
      Galbanum Pyrazine
      As with all pyrazines this is used in tiny traces – galbanum pyrazine at 0.1% in DPG is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum. This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile. Even at this dilution this is a very strong that can enhance or contribute green notes give great diffusion and a very natural effect
  • Indukern F&F
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. We warmly welcome your inquiries, come witness our solemn commitment for yourself.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
  • Pell Wall Perfumes
    • Pell Wall Perfumes
      Hand-made fragrances
      Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock.
      Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home. If you’re looking for something even more exclusive our bespoke fragrance design service could be what you’re looking for: we design custom fragrances for individuals, other perfume brands, hotels, corporations and organisations.
      Email: Info
      Email: Sales
      Voice: +44 1630 652546
      Mobile+44 7792 580511
      Galbanum Pyrazine
      As with all pyrazines this is used in tiny traces – Galbanum Pyrazine at 0.1% in DPG is is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum. This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile. Even at this dilution this is a very strong material that can enhance or contribute to green notes, give great diffusion and a very natural effect.
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      13-22400 2-METHOXY-3-ISOBUTYLPYRAZINE, Kosher
  • Phoenix Aromas & Essential Oils
    • Phoenix Aromas & Essential Oils, Inc.
      EXCEPTIONAL Flavor and Fragrance Ingredients.
      Phoenix sources the finest flavor and fragrance ingredients for its customers.
      Phoenix Aromas & Essential Oils LLC was founded in 1994, grounded in a simple set of core values: provide top-quality products, cost-effective pricing and personalized attention to all our customers. After two decades, we remain committed to those values. With extensive market knowledge of our products, we anticipate, as opposed to merely react, to industry challenges. You can rely on us for all your flavor and fragrance ingredient needs. Customers benefit from Phoenix's long-standing relationships with experienced and reputable growers, processors and manufacturers in key global locations, who are committed to sustainability and green programs. With a strategically located 80,000 sq-ft facility, customers can rely on Phoenix to deliver quality products on time, and cost-effectively.
      Email: EU Info
      US Email: Info
      US Email: Sales
      Voice: +44(0) 208 532 1022
      Fax: +44(0) 208 532 1023
      US Voice: 201-784-6100
      US Fax: 201-784-8566
      Global Reach
      Pyrazine, 2-Methoxy-3-Isobutyl
  • Pyrazine Specialties
  • Robinson Brothers
    • Robinson Brothers Limited
      Providing Excellence in Chemistry
      Award-winning UK chemical manufacturer of chemical intermediates and high-impact aroma chemicals.
      Based in the UK, Robinson Brothers is an award-winning chemical manufacturer of chemical intermediates and high-impact aroma chemicals. Robinson Brothers serve many industry sectors across the globe, include: flavour/fragrance, pharmaceutical, agrochemical and material sciences. Our team of Chemists are experts in custom synthesis, contract manufacture and process optimisation.
      Email: Info
      Email: Sales
      Voice: +44 (0)121 553 2451
      Fax: +44 (0)121 500 5183
      Products List: View
      PZ0250 2-isoButyl-3-methoxypyrazine F&F
  • Sigma-Aldrich
    • Sigma-Aldrich
      Complete Supply Chain
      The perfect blend of products and services that bring your creativity to life.
      Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
      Email: Information
      US Email: Sales
      US Voice: 800-244-1173
      US Fax: 800-368-4661
      Certified Food Grade Products
      W313203 2-Isobutyl-3-methoxypyrazine, ≥99%, FG
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
      Fax: 0512-57570299
      H0026 2-Methoxy-3-isobutyl Pyrazine
  • Taytonn
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
      Email: Info
      Email: Sales
      Voice: + 65 - 6861 8113
      Fax: + 65 - 6861 8115
  • Treatt
    • Treatt PLC
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
      2-IsoButyl-3-methoxypyrazine Halal, Kosher

      Used at very low levels in green vegetable flavours: 0.0005-0.05ppm, and in galbanum substitutes.
  • Ernesto Ventós
  • Vigon International
    • Vigon International, Inc.
      Passion for Simplicity
      Manufacturer and supplier of high quality flavor and fragrance ingredients.
      The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
      US Email: Sales
      US Voice: 570-476-6300
      US Fax: 570-476-1110
      Products List: View
      505003 isoButyl-2 Methoxy-3 Pyrazine
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas
2-methoxy-3-(2-methylpropyl)pyrazine (Click)
CAS Number: 24683-00-9
ECHA EINECS - REACH Pre-Reg: 246-402-1
Nikkaji Web: J126.472I
MDL: MFCD00006128
CoE Number: 11338
XlogP3: 2.60 (est)
Molecular Weight: 166.22378000
Formula: C9 H14 N2 O
BioActivity Summary: listing
NMR Predictor: Predict
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 792  2-isobutyl-3-methoxypyrazine
Flavis Number: 14.043 (Old)
DG SANTE Food Flavourings: 14.043  2-isobutyl-3-methoxypyrazine
FEMA Number: 3132  2-isobutyl-3-methoxypyrazine
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.99250 to 1.00250 @  25.00 °C.
Pounds per Gallon - (est).: 8.259 to  8.342
Refractive Index: 1.48900 to 1.49700 @  20.00 °C.
Boiling Point: 214.00 to  215.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.273000 mm/Hg @ 25.00 °C. (est)
Vapor Density: 5.7 ( Air = 1 )
Flash Point: 176.00 °F. TCC ( 80.00 °C. )
logP (o/w): 2.547 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: green
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 pea green pea  pepper bell pepper  green  galbanum  
Odor Description:
at 0.10 % in dipropylene glycol. 
green pea green bell pepper green pea galbanum
 green  pepper bell pepper  pea green pea  galbanum  
Taste Description:
green bell pepper green pea galbanum
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Advanced Biotech
Anhui Haibei
2-isoButyl-3-methoxy Pyrazine
Anhui Haibei
2-isobutyl-3(5/6) methoxy pyrazine
Odor: Green bell pepper green pea galbanum
Apiscent Labs
2 METHOXY 3 ISOBUTYLPYRAZINE (2-Isobutyl-3-methoxypyrazine)
Odor: Coffee, green pepper
Beijing Lys Chemicals
Citrus and Allied Essences
2-isoButyl-3-Methoxy Pyrazine
Market Report
DeLong Chemicals America
Diffusions Aromatiques
Ernesto Ventós
2-methoxy 3-isobutyl pyrazine
≥99.00% (sum of isomers), NI, Kosher
Odor: Earthy, Galbanum, Green, Green Pea, Pepper.
Use: Suggested Uses: Coffee, Galbanum, Vegetables
Hermitage Oils
Galbanum Pyrazine
Odor: characteristic
Use: As with all pyrazines this is used in tiny traces ľ galbanum pyrazine at 0.1% in DPG is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum. This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile. Even at this dilution this is a very strong that can enhance or contribute green notes give great diffusion and a very natural effect
The Vault
Indukern F&F
Jiangyin Healthway
2-Methoxy-3-isobutyl pyrazine
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-Methoxy-3-isobutyl pyrazine, Kosherk
Lluch Essence
M&U International
Odor: green, pepper
Flavor: strong green note
Pearlchem Corporation
2-Methoxy-3-isobutyl Pyrazine
Pell Wall Perfumes
Galbanum Pyrazine
Odor: bell-pepper, peas, galbanum, natural, nutty, roasted
Use: As with all pyrazines this is used in tiny traces ľ Galbanum Pyrazine at 0.1% in DPG is is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum. This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile. Even at this dilution this is a very strong material that can enhance or contribute to green notes, give great diffusion and a very natural effect.
Penta International
Phoenix Aromas & Essential Oils
Pyrazine, 2-Methoxy-3-Isobutyl
Pyrazine Specialties
also named commonly as 2-Isobutyl-3-Methoxypyrazine
Reincke & Fichtner
Robinson Brothers
2-isoButyl-3-methoxypyrazine F&F
Santa Cruz Biotechnology
For experimental / research use only.
2-isoButyl-3-methoxypyrazine ≥97%
2-Isobutyl-3-methoxypyrazine, ≥99%, FG
Odor: green; vegetable; pepper
Certified Food Grade Products
Sunaux International
2-Methoxy-3-isobutyl Pyrazine
Odor: Earthy, Galbanum, Green, Peppery
For experimental / research use only.
2-isoButyl-3-methoxypyrazine >97.0%(GC)(T)
Tengzhou Jitian Aroma Chemiclal
2-Methoxy -3 - isobutyl pyrazine
Halal, Kosher
Odor: Green pea, green bell-pepper-like
Flavor: Green pea, green bell-pepper-like
Used at very low levels in green vegetable flavours: 0.0005-0.05ppm, and in galbanum substitutes.
Vigon International
isoButyl-2 Methoxy-3 Pyrazine
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
gavage-mouse LD50  2000 mg/kg
(Quest International, 1983a)

gavage-rat LD50  > 4000 mg/kg
(Roure Inc., 1974)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for 2-isobutyl-3-methoxypyrazine usage levels up to:
  0.1000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 1.60 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 1.00 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
Click here to view publication 4
 average usual ppmaverage maximum ppm
baked goods: -0.05000
beverages(nonalcoholic): -0.05000
beverages(alcoholic): --
breakfast cereal: -0.05000
cheese: --
chewing gum: -0.05000
condiments / relishes: -0.05000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.05000
fruit ices: -0.05000
gelatins / puddings: -0.05000
granulated sugar: --
gravies: -0.05000
hard candy: -0.05000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -0.05000
milk products: -0.05000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -0.05000
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
View page or View pdf
Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species
View page or View pdf
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 24683-00-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 32594
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0024683009
Synonyms   Articles   Notes   Search   Top
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 24683-00-9
Pubchem (cid): 32594
Pubchem (sid): 134994257
Flavornet: 24683-00-9
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): HMDB31860
YMDB (Yeast Metabolome Database): YMDB01586
Export Tariff Code: 2933.99.9701
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 acetaldehyde ethyl phenethyl acetalFL/FR
green algae absoluteFL/FR
 allyl amyl glycolateFR
isoamyl benzoateFL/FR
 amyris wood oilFL/FR
 animal carbolactoneFR
 anise seed oil colombiaFL/FR
para-anisyl alcoholFL/FR
 ocimum basilicum herb oilFL/FR
 pimenta acris leaf oilFL/FR
 bean pyrazineFL/FR
siam benzoin resinoidFL/FR
 benzyl alcoholFL/FR
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
 bois de rose oil brazilFL/FR
isobutyl hexanoateFL/FR
 butyl isovalerateFL/FR
S-sec-butyl thioisovalerateFL/FR
 camphor tree bark oilFL/FR
 carum carvi fruit oilFL/FR
 daucus carota fruit oilFL/FR
 thuja occidentalis leaf oilFL/FR
 cinnamyl alcoholFL/FR
 cistus twig/leaf oilFL/FR
 citronellyl acetateFL/FR
 citrus carbaldehydeFR
 clary sage oil franceFL/FR
 clover nitrileFR
 cortex pyridineFL/FR
 costus root oilFL
 costus valerolactoneFR
 cotinus coggygria branch/leaf oilFL/FR
para-cresyl caprylateFL/FR
 cubeb oilFL/FR
 cumin seed oilFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
 decanal (aldehyde C-10)FL/FR
 decyl acetateFL/FR
para-dimethyl hydroquinoneFL/FR
 dodecanal (aldehyde C-12 lauric)FL/FR
 ethyl (Z)-3-hexenoateFL/FR
 ethyl 2-cyclohexyl propionateFR
 ethyl laurateFL/FR
 fir balsam absoluteFR
 fir needle oil siberiaFL/FR
 floral pyranolFR
 flouve absoluteFR
 frankincense oilFL/FR
 galbanum decatrieneFL/FR
 galbascone (IFF)FR
 galbanum oil terpenelessFL/FR
 galbanum oleoresinFL/FR
cis-galbanum oxathianeFL/FR
 galbanum oxyacetateFR
 galbanum resinoidFL/FR
 geranyl acetateFL/FR
(E)-geranyl acetoneFL/FR
 geranyl isobutyrateFL/FR
 grapefruit pentanolFR
 green acetateFR
 green pea pyrazineFL
 heliotropyl diethyl acetalFR
 fleuramone (IFF)FR
2-heptyl tetrahydrofuranFR
(Z)-3-hexen-1-yl benzoateFL/FR
(Z)-3-hexen-1-yl propionateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
 hexyl 2-furoateFL/FR
 hexyl 2-methyl butyrateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 hexyl tiglateFL/FR
 hyacinth etherFR
2,4-ivy carbaldehydeFL/FR
 juniperus communis fruit oilFL/FR
 lavender absolute bulgariaFL/FR
(Z)-leaf acetalFL/FR
 leafy oximeFR
 linalool oxideFL/FR
 levisticum officinale root oilFL/FR
 melon heptenalFL/FR
 melon nonenoateFL/FR
2-methoxy-3-propyl pyrazineFL
 methyl dihydrojasmonateFL/FR
 methyl heptine carbonateFL/FR
 methyl octine carbonateFL/FR
 mimosa absolute franceFL/FR
 muguet carboxaldehydeFR
 muguet octadienolFR
 myrtenyl isobutyrate 
 narcissus flower absoluteFR
 neryl acetateFL/FR
 oakmoss absoluteFL/FR
 ocean propanalFL/FR
 orris pyridine 25% IPMFR
 patchouli ethanoneFR
black pepper oilFL/FR
 phenethyl acetateFL/FR
 phenethyl salicylateFL/FR
 phenyl acetaldehydeFL/FR
 phenyl acetaldehyde dimethyl acetalFL/FR
 phenyl acetic acidFL/FR
3-phenyl propionaldehydeFL/FR
3-phenyl propyl alcoholFL/FR
 pineapple heptadienone 10%FR
 propyl 2,4-decadienoateFL/FR
isopropyl 3-methyl thiocrotonateFL/FR
isopropyl thioisovalerateFL/FR
 raspberry ketone methyl etherFL/FR
 reseda acetalFR
 rhubarb undecaneFR
 shoyu pyrazineFL/FR
 sorbyl isobutyrateFL/FR
 spruce needle oil canadaFL/FR
 strawberry furanoneFL/FR
 styralyl acetateFL/FR
 tobacarol (IFF)FR
 tonka bean absoluteFR
2-tropical oxathianeFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
 veramoss (IFF)FR
 vetiver oil haitiFL/FR
 violet dienyneFR
 violet methyl carbonateFR
 watermelon ketoneFR
 woody acetateFR
(Z)-woody amyleneFR
 woody propanolFR
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 apple crabapple 
 ash mountain ash 
 boxwood blossom 
 champaca champakFR
 cherry wildFL
 cloudberry bakeapple 
 daffodil narcissusFR
 earth humusFR
 eglantine sweet briarFR
 fern fougereFR
 fir needle pine needleFL/FR
 forest pine forestFR
 fresh & cleanFR
 grass sweetFR
 green grassFR
 green leafFR
 hops houblonFL/FR
 hyacinth jacintheFR
 jonquil narcissus jonquillaFR
 muguet lily of the valleyFR
 narcissus narcisseFR
 oakmoss mousse de chene mossFR
 ocean sea 
 orange bitterFL/FR
 pea green pea 
 pepper greenFL
 privet blossom 
 rain springFR
 reseda mignonetteFR
 rose geraniumFR
 strawberry leaf 
 tea greenFR
 tomato leafFR
 wormwood absinthiumFL/FR
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Natural Occurrence in: note
 bean green bean
GRIN Trop Picture
 citrus nobilis lour. var. microcarpa hassk.
GRIN Trop Picture
 galbanum oil
GRIN Trop Picture
 parsnip root
 pea green pea
 pepper bell pepper green pepper
 potato products
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isobutyl methoxypyrazine
2-isobutyl-3-methoxy pyrazine
 galbanum pyrazine
2-methoxy 3 iso butyl pyrazine
2 methoxy 3 isobutylpyrazine (2-isobutyl-3-methoxypyrazine)
2-methoxy 3-isobutyl pyrazine
2-methoxy-3-(2-methyl propyl) pyrazine
2-methoxy-3-isobutyl pyrazine
2-methoxy-3-isobutyl pyrazine 1% DPG
2-methoxy-3(6)-isobutyl pyrazine
2-2-methyl propyl-3-methoxypyrazine
 pyrazine, 2-isobutyl-3-methoxy-
 pyrazine, 2-methoxy-3-(2-methylpropyl)-
 pyrazine, 2-methoxy-3-isobutyl
Synonyms   Articles   Notes   Search   Top
PubMed: Key aroma compounds in roasted in-shell peanuts.
PubMed: Comparison of the key aroma compounds in organically grown, raw West-African peanuts (Arachis hypogaea) and in ground, pan-roasted meal produced thereof.
PubMed: Growth behavior of off-flavor-forming microorganisms in apple juice.
PubMed: Odor thresholds of microbially induced off-flavor compounds in apple juice.
PubMed: Effect of cultivar and storage time on the volatile flavor components of baked potato.
PubMed: Characteristic aroma components of British Farmhouse Cheddar cheese.
PubMed: Solid-phase microextraction method development for headspace analysis of volatile flavor compounds.
PubMed: Electrochemical detection of the 2-isobutyl-3-methoxypyrazine model odorant based on odorant-binding proteins: The proof of concept.
PubMed: Dynamics of odorant binding to thin aqueous films of rat-OBP3.
PubMed: Identification of a specific olfactory receptor for 2-isobutyl-3-methoxypyrazine.
PubMed: Selectable one-dimensional or two-dimensional gas chromatography-olfactometry/mass spectrometry with preparative fraction collection for analysis of ultra-trace amounts of odor compounds.
PubMed: A systematic study on spatial and seasonal patterns of eight taste and odor compounds with relation to various biotic and abiotic parameters in Gonghu Bay of Lake Taihu, China.
PubMed: Following in their footprints: cuticular hydrocarbons as overwintering aggregation site markers in Hippodamia convergens.
PubMed: Simultaneous determination of ten taste and odor compounds in drinking water by solid-phase microextraction combined with gas chromatography-mass spectrometry.
PubMed: A methyltransferase essential for the methoxypyrazine-derived flavour of wine.
PubMed: The role of semiochemicals in short-range location of aggregation sites in Adalia bipunctata (Coleoptera, Coccinellidae).
PubMed: Defensive allomones function as aggregation pheromones in diapausing Ladybird Beetles, Hippodamia convergens.
PubMed: Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a major grape-derived aroma compound impacting wine quality.
PubMed: Detection and quantification of natural contaminants of wine by gas chromatography-differential ion mobility spectrometry (GC-DMS).
PubMed: Key aroma compounds in roasted in-shell peanuts.
PubMed: Behavior of 3-isobutyl-2-hydroxypyrazine (IBHP), a key intermediate in 3-isobutyl-2-methoxypyrazine (IBMP) metabolism, in ripening wine grapes.
PubMed: Classification of grape berries according to diameter and total soluble solids to study the effect of light and temperature on methoxypyrazine, glutathione, and hydroxycinnamate evolution during ripening of Sauvignon blanc (Vitis vinifera L.).
PubMed: Fruit ripening in Vitis vinifera: light intensity before and not during ripening determines the concentration of 2-methoxy-3-isobutylpyrazine in Cabernet Sauvignon berries.
PubMed: Occurrence of dissolved and particle-bound taste and odor compounds in Swiss lake waters.
PubMed: Accurate analysis of trace earthy-musty odorants in water by headspace solid phase microextraction gas chromatography-mass spectrometry.
PubMed: The effect of pyrazine odor on body weight and the weight of various organs in chicks (Gallus gallus domesticus).
PubMed: Simultaneous determination of eight common odors in natural water body using automatic purge and trap coupled to gas chromatography with mass spectrometry.
PubMed: Purification and characterization of two odorant-binding proteins from nasal tissue of rabbit and pig.
PubMed: Development of a mixed-mode solid phase extraction method and further gas chromatography mass spectrometry for the analysis of 3-alkyl-2-methoxypyrazines in wine.
PubMed: 2-Methoxy-3-isobutylpyrazine in grape berries and its dependence on genotype.
PubMed: Effect of enzyme activity and frozen storage on jalape├▒o pepper volatiles by selected ion flow tube-mass spectrometry.
PubMed: Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein.
PubMed: Long-timescale molecular-dynamics simulations of the major urinary protein provide atomistic interpretations of the unusual thermodynamics of ligand binding.
PubMed: Identification of alkyl-methoxypyrazines as the malodorous compounds in water supplies from Northwest Spain.
PubMed: Automated trace determination of earthy-musty odorous compounds in water samples by on-line purge-and-trap-gas chromatography-mass spectrometry.
PubMed: Why has porcine VEG protein unusually high stability and suppressed binding ability?
PubMed: Three odorant-binding proteins from rabbit nasal mucosa.
PubMed: Multiple types and forms of odorant-binding proteins in the Old-World porcupine Hystrix cristata.
PubMed: Ligand-binding properties and structural characterization of a novel rat odorant-binding protein variant.
PubMed: Odorant-binding proteins of the mouse.
PubMed: Purification and characterisation of an odorant-binding protein from cow nasal tissue.
PubMed: Survey of 3-alkyl-2-methoxypyrazine content of South African Sauvignon blanc wines using a novel LC-APCI-MS/MS method.
PubMed: Rapid measurement of 3-alkyl-2-methoxypyrazine content of winegrapes to predict levels in resultant wines.
PubMed: Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry.
PubMed: Structural basis of the broad specificity of a general odorant-binding protein from honeybee.
PubMed: Odor thresholds of microbially induced off-flavor compounds in apple juice.
PubMed: The molecular basis for wine grape quality--a volatile subject.
PubMed: Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water.
PubMed: Removal of earthy-musty odorants in drinking water by powdered activated carbon.
PubMed: Effect of cultivar and storage time on the volatile flavor components of baked potato.
PubMed: The determination of six taste and odour compounds in water using Ambersorb 572 and high resolution mass spectrometry.
PubMed: Odorant and pheromone binding by aphrodisin, a hamster aphrodisiac protein.
PubMed: Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes.
PubMed: Quantitative determination of 2-methoxy-3-isobutylpyrazine in red wines and grapes of Bordeaux using a stable isotope dilution assay.
PubMed: Membrane receptor for odour-binding proteins.
PubMed: Odorant-sensitive adenylate cyclase: rapid, potent activation and desensitization in primary olfactory neuronal cultures.
PubMed: Activation by odorants of a multistate cation channel from olfactory cilia.
PubMed: The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.
PubMed: Isolation and characterization of an olfactory receptor protein for odorant pyrazines.
PubMed: A survey of seasonal temperatures and vineyard altitude influences on 2-methoxy-3-isobutylpyrazine, C13-norisoprenoids, and the sensory profile of Brazilian Cabernet Sauvignon wines.
PubMed: Determination of characteristic odorants from Harmonia axyridis beetles using in vivo solid-phase microextraction and multidimensional gas chromatography-mass spectrometry-olfactometry.
PubMed: Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding.
PubMed: Influence of vine training and sunlight exposure on the 3-alkyl-2-methoxypyrazines content in musts and wines from the Vitis vinifera variety cabernet sauvignon.
PubMed: Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein.
PubMed: Absolute configuration of 2-sec-butyl-4,5-dihydrothiazole in male mouse urine.
PubMed: Characteristic aroma components of British Farmhouse Cheddar cheese.
PubMed: Solid-phase microextraction method development for headspace analysis of volatile flavor compounds.
PubMed: Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation.
PubMed: Conformational stability and binding properties of porcine odorant binding protein.
PubMed: Subtypes of odorant-binding proteins--heterologous expression and ligand binding.
PubMed: Lipocalins of boar salivary glands binding odours and pheromones.
PubMed: Isolation of two odorant-binding proteins from mouse nasal tissue.
PubMed: Ligand binding characteristics of homologous rat and mouse urinary proteins and pyrazine-binding protein of calf.
PubMed: Ultrastructural characteristics of sustentacular cells in control and odorant-treated olfactory mucosae of the salamander.
PubMed: Odorant stimulation of secretory and neural processes in the salamander olfactory mucosa.
PubMed: Immunocytochemical localization of pyrazine-binding protein in bovine nasal mucosa.
PubMed: Occurrence of a pyrazine binding protein in the nasal mucosa of some vertebrates.
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Picture of molecule
Soluble in:
 water, 229.6 mg/L @ 25 °C (est)
 stable in most media
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