Articles:
| None found yet. Try the PubMed Search. |
Notes:
None found
| Name: | 4-hydroxy-2,5-dimethylfuran-3-one solution | |
| CAS Number: | 3658-77-3 |  3D/inchi
|
| % from: | 20.00% | |
| ECHA EINECS - REACH Pre-Reg: | 222-908-8 | |
| Nikkaji Web: | J13.291H | |
| Beilstein Number: | 1281357 | |
| MDL: | MFCD00010706 | |
| FEMA Number: | 3174 | |
| CoE Number: | 536 | |
| XlogP3-AA: | 0.70 (est) | |
| Molecular Weight: | 128.12736000 | |
| Formula: | C6 H8 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| Also(can) Contains: | dipropylene glycol 80.00% | |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
| JECFA Food Flavoring: | 1446 4-hydroxy-2,5-dimethyl-3(2H)-furanone solution |
| Flavis Number: | 13.010 (Old) |
| DG SANTE Food Flavourings: | 13.010 4-hydroxy-2,5-dimethylfuran-3(2H)-one solution |
| FEMA Number: | 3174 4-hydroxy-2,5-dimethyl-3(2H)-furanone solution |
Physical Properties:
| Appearance: | colorless to pale yellow clear oily liquid (est) |
| Assay: | 19.00 to 21.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.01900 to 1.02100 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 8.479 to 8.496 |
| Refractive Index: | 1.43000 to 1.45000 @ 20.00 °C. |
| Flash Point: | 200.00 °F. TCC ( 93.33 °C. ) |
| logP (o/w): | 0.340 |
| Shelf Life: | 12.00 month(s) or longer if stored properly. |
| Storage: | store under nitrogen. |
| Storage: | refrigerate in tightly sealed containers. store under nitrogen. |
| Soluble in: | |
| alcohol | |
| propylene glycol | |
| water, slightly | |
| water, 1.85e+004 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: | caramellic |
| Odor Strength: | high |
| Odor Description: at 100.00 %. | sweet cotton candy strawberry sugar |
| Substantivity: | 400 Hour(s) |
Cosmetic Information:
| None found |
Safety Information:
| Most important hazard(s): | |
| Xn - Harmful. | |
|
R 22 - Harmful if swallowed. S 36 - Wear suitable protective clothing. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 1608 mg/kg CHYCDW 22,85,1988 | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| Recommendation for strawberry furanone 20% dpg usage levels up to: | |||
| 5.0000 % in the fragrance concentrate. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 4 | |||
| Click here to view publication 4 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 10.00000 | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | - | 60.00000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 5.00000 | |
| fruit ices: | - | 5.00000 | |
| gelatins / puddings: | - | 5.00000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 10.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| List of apha, beta-Unsaturated Aldehydes and Ketones representative of FGE.19 substances for Genotoxicity Testing [1] - Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf | |
| Flavouring Group Evaluation 220: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 220, Revision 1 (FGE.220Rev1): alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 99 (FGE.99): Consideration of furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings) View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Env. Mutagen Info. Center: | Search |
| NLM Developmental and Reproductive Toxicity: | Search |
| EPA Substance Registry Services (TSCA): | 3658-77-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 19309 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 4-hydroxy-2,5-dimethylfuran-3-one solution | |
| Chemidplus: | 0003658773 |
| RTECS: | LU3990000 for cas# 3658-77-3 |
References:
| 4-hydroxy-2,5-dimethylfuran-3-one solution | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 3658-77-3 |
| Pubchem (cid): | 19309 |
| Pubchem (sid): | 134985325 |
| Flavornet: | 3658-77-3 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2009 |
| (IUPAC): | Atomic Weights of the Elements 2009 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Everything Added to Food in the United States (EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C20717 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2914.70.9000 |
| ChemSpider: | View |
| Wikipedia: | View |
| RSC Learn Chemistry: | View |
Potential Blenders and core components note
Potential Uses:
| almond toasted almond | FL | |
| beeswax absolute replacer | FR | |
| blackberry | FR | |
| blossom tropical blossom | ||
| blueberry | FR | |
| boysenberry | FR | |
| bread | FL | |
| butterscotch | FR | |
| cake | FL | |
| cappuccino | FL | |
| caramel | FL | |
| cassia | FR | |
| cereal | FL | |
| cherry | FR | |
| chocolate cacao | FL | |
| chocolate cocoa | FL | |
| coconut | FR | |
| coconut tropical coconut | FR | |
| coffee | FR | |
| cookie | FL | |
| cotton candy | FR | |
| currant | FR | |
| date | FR | |
| fantasy blends | ||
| fig | FR | |
| filbert | FR | |
| fir balsam | FR | |
| fruit | FR | |
| fruit jam | ||
| fruit punch | FL | |
| fruit tropical fruit | FL | |
| gingerbread | FR | |
| gooseberry | FR | |
| graham cracker | FR | |
| grape | FR | |
| guava | FR | |
| hay new mown hay | FR | |
| hibiscus | FR | |
| honey | FR | |
| huckleberry | FR | |
| loganberry | FR | |
| malt | FR | |
| mango | FR | |
| mango flower | FR | |
| maple | FR | |
| marshmallow | FL | |
| melon | FR | |
| molasses | FL | |
| nut | FL | |
| passion blossom | FR | |
| passion fruit | FR | |
| pina colada | FR | |
| pineapple | FR | |
| popcorn | FR | |
| praline | FL | |
| pumpkin pie | FR | |
| quince | FR | |
| raspberry | FR | |
| rum butter | FL | |
| strawberry | FR | |
| strawberry jam | ||
| sugar brown sugar | FL | |
| tobacco | FR | |
| toffee | FR | |
| tropical | FL | |
| valerian | FL/FR | |
| vanilla | FR |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| carmelan (Elan) | |
| dimethyl hydroxyfuranone solution | |
| 2,5- | dimethyl-4-hydroxy-3(2H)-furanone solution |
| furaneol 15% in PG | |
| furaneol 20% in ethyl alcohol | |
| furaneol 20% in PG | |
| furaneol solution | |
| furanone 10% in ETOH natural | |
| furanone 10% in PG natural | |
| furanone 10% in PG synthetic | |
| furanone 12% in ETOH natural | |
| furanone 12% in PG synthetic | |
| furanone 15% in ETOH natural | |
| furanone 15% in PG natural | |
| furanone 15% in PG synthetic | |
| furanone 15% in triacetin (OS) natural | |
| furanone 20% ETOH synthetic | |
| furanone 20% in ETOH natural | |
| furanone 20% in PG natural | |
| furanone 20% in PG synthetic | |
| furanone 25% in ETOH natural | |
| furanone 25% in PG natural | |
| furanone 25% in PG synthetic | |
| furanone 3% in vegetable oil synthetic | |
| 4- | hydroxy 2.5.dimethyl 3(2H) furanone 20% in ethanol, natural |
| 4- | hydroxy 2.5.dimethyl 3(2H) furanone 20% in PG, natural |
| hydroxy-2,5-dimethyl-3(2H) furanone natural 15% in P.G. | |
| hydroxy-2,5-dimethyl-3(2H) furanone natural 20% in P.G. | |
| hydroxy-2,5-dimethyl-3(2H)-furanone 20% in P.G. | |
| 4- | hydroxy-2,5-dimethyl-3(2H)-furanone solution |
| 4- | hydroxy-2,5-dimethyl-3(2H)furanone 15% in PG |
| 4- | hydroxy-2,5-dimethyl-3(2H)furanone 20% in PG |
| 4- | hydroxy-2,5-dimethylfuran-3(2H)-one solution |
| 4- | hydroxy-2,5-dimethylfuran-3-one solution |
| pineapple compound solution | |
| pineapple ketone solution | |
| strawberry furanone 1% dpg | |
| strawberry furanone 10% dpg | |
| strawberry furanone 15% in ethanol (natural) | |
| strawberry furanone 15% in PG (natural) | |
| strawberry furanone 20% DPG | |
| strawberry furanone 20% in D.A. natural | |
| strawberry furanone 20% in PG | |
| strawberry furanone 20% in PG natural | |
| strawberry furanone natural 15% in ethyl alcohol | |
| strawberry furanone natural 15% in PG | |
| strawberry furanone natural 20% in ethyl alcohol | |
| strawberry furanone natural 25% in ethyl alcohol | |
| strawberry furanone natural 25% in PG | |
| strawberry furanone solution | |
| walnut furanone solution |