EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro,laevo-muscone
3-methyl-1-cyclopentadecanone

Supplier Sponsors

Fragrance Demo Formulas
Name:3-methylcyclopentadecan-1-one
CAS Number: 541-91-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-795-8
FDA UNII:5JO79R7S9R
Nikkaji Web:J6.397E
MDL:MFCD00211114
CoE Number:11135
XlogP3-AA:6.20 (est)
Molecular Weight:238.41430000
Formula:C16 H30 O
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
JECFA name: 3-Methyl-1-cyclopentadecanone.
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1402 3-methyl-1-cyclopentadecanone
FEMA Number:3434 3-methyl-1-cyclopentadecanone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):541-91-3 ; 3-METHYL-1-CYCLOPENTADECANONE
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.91800 to 0.92500 @ 25.00 °C.
Pounds per Gallon - (est).: 7.639 to 7.697
Refractive Index:1.47700 to 1.48100 @ 20.00 °C.
Melting Point: 8.60 °C. @ 760.00 mm Hg
Boiling Point: 320.00 to 329.00 °C. @ 760.00 mm Hg
Boiling Point: 130.00 °C. @ 0.50 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.000176 mmHg @ 25.00 °C. (est)
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 6.100 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 water, very slightly
 water, 0.2213 mg/L @ 25 °C (est)
Stability:
 APC: -
 candle: traces - 0.5%
 detergent: traces - 0.5%
 fine fragrances: 0.1 - 2%
 shampoo: traces - 0.5%
 shower gel: traces - 0.5%
 soap: traces - 0.5%
 softener: traces - 0.5%
 
Organoleptic Properties:
Odor Type: musk
Odor Strength:high ,
recommend smelling in a 10.00 % solution or less
Substantivity:400 hour(s) at 100.00 %
sweet musk animal powdery fatty natural
Odor Description:at 10.00 % in dipropylene glycol. sweet musk animal powdery fatty natural
Luebke, William tgsc, (1986)
Odor sample from: Firmenich Inc.
sweet floral musk soapy
Odor Description:at 0.20 %. sweet fragrant perfume, musky with floral and soapy shaving cream like nuances.
Mosciano, Gerard, (2009)
Flavor Type: musk
sweet musk floral soapy woody bitter
Taste Description: at 1.00 ppm. sweet, musk like, perfume, soapy with woody and bitter nuances
Mosciano, Gerard, (2009)
Odor and/or flavor descriptions from others (if found).
Firmenich
MUSCONE
Odor Description:A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
It can be used to give elegant and warm animal notes and adds lift and diffusion to any perfume. Important for the reconstitution of natural musk.
Pell Wall Perfumes
Muscone
Odor Description:Musk, powdery, soft, animalic. Exalting. Fixative
According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”.
IFF
Muscor
Odor Description:Soft, sweet, musky with animalic tonalities
Perfumery Laboratory
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich)
Odor Description:trong aroma of Thonky musk, which has good diffusion
Takasago
l-Muscone
Odor Description:musk animal powdery
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
A.C.S. International
Muscone
Odor: sweet musk floral woody soapy
Operational Capabilities
Augustus Oils
Muscone
Services
Azelis UK
MUSCONE
Services
BOC Sciences
For experimental / research use only.
Muscone >98%
Coompo
For experimental / research use only.
Muscone from Plants ≥98%
Ernesto Ventós
MUSCONE FIRMENICH 962195
Odor: VERY SOFT, SWEET, MUSKY
Fine Fragrances Pvt Ltd
Muscone
Firmenich
MUSCONE
Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
Use: It can be used to give elegant and warm animal notes and adds lift and diffusion to any perfume. Important for the reconstitution of natural musk.
IFF
Muscor
Odor: Soft, sweet, musky with animalic tonalities
Indukern F&F
MUSCONE
Odor: SMOOTH, SWEET, MUSK
Liaison Carbone
MUSCONE LAEVO 954117
M&U International
Muscone
Moellhausen
MUSCONE
Odor: musky, slightly fruity, erogenic
Pell Wall Perfumes
Muscone
Odor: Musk, powdery, soft, animalic. Exalting. Fixative
Use: According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”.
Penta International
3-METHYL-1-CYCLOPENTADECANONE
Perfumer Supply House
L-Muscone (Takasago) – for a limited time
Odor: The key component of musk, this synthetic version has a sweet, powdery, animalic aroma
Perfumery Laboratory
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich)
Odor: trong aroma of Thonky musk, which has good diffusion
Prodasynth
MUSCONE
(> 95%)
Odor: SOFT, SWEET, MUSKY
Santa Cruz Biotechnology
For experimental / research use only.
Muscone ≥98%
Takasago
l-Muscone
Odor: musk animal powdery
The Fragrance Museum
TCI AMERICA
For experimental / research use only.
Muscone >97.0%(GC)
Vigon International
Muscone
Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
30 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 [sex: M,F] > 5000 mg/kg
(Oh et al., 1997)

intravenous-mouse LD50 152 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.

intraperitoneal-mouse LD50 270 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.

oral-rat LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for dextro,laevo-muscone usage levels up to:
  2.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.37 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.009 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 8
 average usual ppmaverage maximum ppm
baked goods: -0.05000
beverages(nonalcoholic): -0.03000
beverages(alcoholic): -0.02000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: -0.05000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.03000
fruit ices: -0.03000
gelatins / puddings: -0.02000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

EPI System: View
NLM Hazardous Substances Data Bank:Search
Cancer Citations:Search
Toxicology Citations:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):541-91-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10947
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
3-methylcyclopentadecan-1-one
Chemidplus:0000541913
RTECS:GY0950000 for cas# 541-91-3
 
References:
Leffingwell:Chirality or Article
 3-methylcyclopentadecan-1-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:541-91-3
Pubchem (cid):10947
Pubchem (sid):134976141
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB34181
FooDB:FDB012473
Export Tariff Code:2914.29.5000
Haz-Map:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
the dried, unopened pouches of commerce are distinguished by the following names: tonquin, blue skin, yunnann, sawko, cabardin, nepal, & assam. good quality pouches contain approx 70% musk, while less valuable ones contain as little as 40% musk. musk
 
Potential Blenders and core components note
For Odor
aldehydic
citronellyl oxyacetaldehyde
FL/FR
9-
decenal
FL/FR
dodecanal (aldehyde C-12 lauric)
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
amber
ambergris naphthol
FR
ambrette seed oil
FL/FR
alpha-
ambrinol
FL/FR
ambrinol
FR
ambroxan
FL/FR
angelica root oil
FL/FR
cistus ladaniferus resinoid
FR
animal
animal carbolactone
FR
animal specialty
FR
iso
butyl quinoline
FR
iso
butyl quinoline
FR
para-
cresyl caprylate
FL/FR
musk indenofuran
FR
procavia capensis excrete absolute
FR
anisic
para-
anisaldehyde
FL/FR
balsamic
iso
amyl benzoate
FL/FR
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzophenone
FR
benzyl cinnamate
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
cinnamyl alcohol
FL/FR
clover nitrile
FR
ethyl cinnamate
FL/FR
fir balsam absolute
FR
methyl cinnamate
FL/FR
3-
phenyl propyl alcohol
FL/FR
berry
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
caramellic
ethyl maltol
FL/FR
citrus
bergamot oil
FL/FR
grapefruit pentanol
FR
blood
orange oil italy
FL/FR
earthy
muscogene
FR
fatty
decanol
FL/FR
floral
alpha-
amyl cinnamaldehyde
FL/FR
iso
amyl salicylate
FL/FR
benzyl acetate
FL/FR
bois de rose oil brazil
FL/FR
iso
butyl salicylate
FL/FR
citronellol
FL/FR
coriander seed oil
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
alpha-
damascone
FL/FR
9-
decen-1-ol
FL/FR
dimethyl benzyl carbinol
FL/FR
ethyl phenyl acetate
FL/FR
floral pyranol
FR
gardenia oxide
FR
geraniol
FL/FR
heliotropin
FL/FR
heliotropyl diethyl acetal
FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hyacinth ether
FR
hydroxycitronellal
FL/FR
(Z)-
jasmone
FL/FR
leerall
FR
lilyall
FR
laevo-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
para-
methyl acetophenone
FL/FR
methyl dihydrojasmonate
FL/FR
muguet carboxaldehyde
FR
muguet octadienol
FR
nerol
FL/FR
nerolidol
FL/FR
nonanol
FL/FR
ocean propanal
FL/FR
orris pyridine 25% IPM
FR
peony alcohol
FR
phenethyl alcohol
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl phenyl acetate
FL/FR
phenethyl propionate
FL/FR
phenethyl salicylate
FL/FR
rhodinol
FL/FR
rose butanoate
FL/FR
tetrahydrolinalool
FL/FR
violet methyl carbonate
FR
fresh
10-
undecen-1-yl acetate
FL/FR
fruity
allyl amyl glycolate
FR
benzyl propionate
FL/FR
beta-
damascone
FL/FR
gamma-
decalactone
FL/FR
green acetate
FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl benzoate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-
leaf acetal
FL/FR
melon nonenoate
FL/FR
valerian rhizome oil CO2 extract china
FL/FR
violet leaf absolute
FL/FR
hay
beeswax absolute
FL/FR
hay absolute
FR
herbal
clary sage oil france
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
linalyl acetate
FL/FR
valerian rhizome oil
FL/FR
valerian rhizome oil china
FL/FR
honey
methyl phenyl acetate
FL/FR
melon
watermelon ketone
FR
mossy
oakmoss absolute
FL/FR
veramoss (IFF)
FR
musk
(Z)-
ambrettolide
FL/FR
(3alpha,5alpha)-
androst-16-en-3-ol
FR
cyclohexadecanone
FR
ethylene dodecanoate
FR
exaltone (Firmenich)
FR
juniper muscone
FR
delta-
muscenone
FR
(R)-
muscone
FR
musk amberol
FR
musk cyclopentenyl propionate
FR
musk dimethyl indane
FL/FR
musk indane
FR
musk nonane
FR
(Z)-
musk pentane
FR
musk tetralin
FR
musk tibetene (Givaudan)
CS
musk xylol
CS
omega-
pentadecalactone
FL/FR
polvolide (Soda)
FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
powdery
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
spicy
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
methyl isoeugenol
FL/FR
terpenic
frankincense oil
FL/FR
alpha-
terpineol
FL/FR
tonka
coumarin
FR
tonka bean absolute
FR
vanilla
ethyl vanillin
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decyl acetate
FL/FR
1-
dodecanol
FL/FR
ethyl laurate
FL/FR
1-
undecanol
FL/FR
woody
amber carbinol
FR
cistus twig/leaf oil
FL/FR
guaiacwood oil
FL/FR
gurjun balsam oil
FR
longifolene
FL/FR
methyl cedryl ketone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
santall
FR
tobacarol (IFF)
FR
vetiver oil haiti
FL/FR
woody acetate
FR
(Z)-
woody amylene
FR
woody propanol
FR
For Flavor
No flavor group found for these
(Z)-
ambrettolide
FL/FR
9-
decenal
FL/FR
beta-
damascone
FL/FR
aldehydic
aldehydic
1-
undecanol
FL/FR
amber
ambrette seed oil
FL/FR
alpha-
ambrinol
FL/FR
animal
para-
cresyl caprylate
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
butyl cinnamate
FL/FR
ethyl cinnamate
FL/FR
berry
raspberry ketone
FL/FR
raspberry ketone acetate
FL/FR
raspberry ketone methyl ether
FL/FR
brown
beeswax absolute
FL/FR
caramellic
ethyl maltol
FL/FR
cherry
heliotropin
FL/FR
citrus
bergamot oil
FL/FR
citronellyl oxyacetaldehyde
FL/FR
laevo-
linalool
FL/FR
linalool
FL/FR
nerol
FL/FR
blood
orange oil italy
FL/FR
alpha-
terpineol
FL/FR
cooling
iso
butyl salicylate
FL/FR
creamy
para-
anisaldehyde
FL/FR
para-
methyl acetophenone
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
fatty
(Z)-3-
hexen-1-yl benzoate
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
bois de rose oil brazil
FL/FR
citronellol
FL/FR
geraniol
FL/FR
linalyl acetate
FL/FR
methyl dihydrojasmonate
FL/FR
methyl phenyl acetate
FL/FR
ocean propanal
FL/FR
phenethyl alcohol
FL/FR
phenethyl propionate
FL/FR
rhodinol
FL/FR
tetrahydrolinalool
FL/FR
fruity
iso
amyl benzoate
FL/FR
para-
anisyl acetate
FL/FR
para-
anisyl alcohol
FL/FR
benzyl acetate
FL/FR
benzyl propionate
FL/FR
alpha-
damascone
FL/FR
gamma-
decalactone
FL/FR
rose butanoate
FL/FR
valerian rhizome oil
FL/FR
valerian rhizome oil china
FL/FR
valerian rhizome oil CO2 extract china
FL/FR
greasy
10-
undecen-1-yl acetate
FL/FR
green
iso
amyl salicylate
FL/FR
angelica root oil
FL/FR
cinnamyl alcohol
FL/FR
cyclamen aldehyde
FL/FR
cyclohexyl ethyl alcohol
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
(Z)-
leaf acetal
FL/FR
linalool oxide
FL/FR
melon nonenoate
FL/FR
nerolidol
FL/FR
oakmoss absolute
FL/FR
violet leaf absolute
FL/FR
herbal
clary sage oil france
FL/FR
coriander seed oil
FL/FR
daucus carota fruit oil
FL/FR
lavender absolute bulgaria
FL/FR
honey
ethyl phenyl acetate
FL/FR
phenethyl isobutyrate
FL/FR
phenethyl phenyl acetate
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
phenethyl salicylate
FL/FR
musk
musk dimethyl indane
FL/FR
powdery
beta-
naphthyl ethyl ether
FL/FR
roasted
acer spicatum bark extract
FL
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
1-
dodecanol
FL/FR
spicy
benzyl cinnamate
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
methyl cinnamate
FL/FR
methyl isoeugenol
FL/FR
3-
phenyl propyl alcohol
FL/FR
tropical
alpha-
amyl cinnamaldehyde
FL/FR
vanilla
ethyl vanillin
FL/FR
omega-
pentadecalactone
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanillyl acetate
FL/FR
waxy
decanol
FL/FR
9-
decen-1-ol
FL/FR
decyl acetate
FL/FR
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
nonanol
FL/FR
woody
ambroxan
FL/FR
amyris wood oil
FL/FR
cistus twig/leaf oil
FL/FR
frankincense oil
FL/FR
guaiacwood oil
FL/FR
(Z)-
jasmone
FL/FR
longifolene
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
vetiver oil haiti
FL/FR
 
Potential Uses:
FRacacia
FRamber
FRambergris
FRambrette oil replacer
FL/FRangelica
FRanimal
FRautumn
FRazalea
FRbalsam
FRbark
FRbayberry
FRbeeswax absolute replacer
FRboronia
FRbouquet
FRcabreuva wood
FRcassia blossom
FRcedar
FRcedar forest
FRchampaca
FLchocolate cacao
FRchypre
FL/FRcistus
FRcivet
 clean
FRclover
FRcolonia
FRcountry meadow
FRcyclamen
FRdaffodil
FRdaphne
FRdogwood
 dusty
 fantasy blends
FRfern
FRfig
FRfir balsam
FRfir needle oil replacer
 fixer
FRfloral
FRflouve
FRflouve blossom
FRfoliage
FRfrangipani plumeria
FRfreesia
FRgenet
FRginger white ginger
FL/FRguaiacwood
FRgurjun balsam
FRhawthorn
FRhay new mown hay
FRheather
FRherbal
FRhinoki oil replacer
FRhollyberry
FRhugonia
FL/FRimmortelle
FRincense
FRkiwi blossom
FRlabdanum
FRlavender
FRleather
FRlily
FRlily of the valley
FRlotus
FRmillefleurs
FRmimosa
FRmoss
FRmusk
 muskrat
FRnarcissus
FRoakwood
FRocean sea
FRorange blossom
FRorchid
FRoriental
FRpansy
FRpassion blossom
FRpatchouli
FRpetunia
FRphlox
FRpine
FRpine forest
FRpoppy
FRpowder
FRprivet blossom
FRrain
FRreseda
FRrose
FRrose d'orient
FRrose red rose
FRrose tea rose
FRrose white rose
 rose wild rose
FRsandalwood
FRsoapy sandalwood moss
FRspice
FRspring rain
FRstephanotis
FRsweet grass
 timber
FRtobacco
FRtonka bean
FRtulip
FRvanilla
FRwisteria
FRwoodruff
FRwoody
 
Occurrence (nature, food, other):note
 musk natural
Search PMC Picture
 
Synonyms:
 cyclopentadecanone, 3-methyl-
3-methyl cyclopentadecan-1-one
3-methyl cyclopentadecanone
 methyl exaltone
3-methyl-1-cyclopentadecanone
3-methyl-cyclopentadecanone
3-methylcyclopentadecan-1-one
3-methylcyclopentadecanone
 methylexaltone
 moschus ketone
dextro,laevo-muscone
DL-muscone
 muscone (Firmenich)
 muscor (IFF)
 muskone
 

Articles:

Info:Muscone
PubMed:Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy.
PubMed:Beneficial effects of muscone on cardiac remodeling in a mouse model of myocardial infarction.
PubMed:Chinese herbs and their active ingredients for activating xue (blood) promote the proliferation and differentiation of neural stem cells and mesenchymal stem cells.
PubMed:Neuroprotective effect of muscone on glutamate-induced apoptosis in PC12 cells via antioxidant and Ca(2+) antagonism.
PubMed:Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors.
PubMed:Anti-inflammatory effects of 4-methylcyclopentadecanone on edema models in mice.
PubMed:Effects of Qishe Pill, a compound traditional Chinese herbal medicine, on cervical radiculopathy: study protocol for a randomized controlled trial.
PubMed:Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model.
PubMed:Metabolomic strategy for studying the intervention and the synergistic effects of the shexiang baoxin pill for treating myocardial infarction in rats.
PubMed:Fast and direct quantification of underivatized muscone by ultra performance liquid chromatography coupled with evaporative light scattering detection.
PubMed:[Effect of borneol on intestinal absorption of muscone in rats].
PubMed:[Analysis of muscone from serum and cerebrospinal fluid of rabbits after intragastric administration of tongqiao huoxue granules].
PubMed:[Determination method of muscone in rat intestinal perfusate by GC-MS/MS and its intestinal absorption kinetic characteristics in rats].
PubMed:Muscone exerts neuroprotection in an experimental model of stroke via inhibition of the fas pathway.
PubMed:Efficient macrocyclization by a novel oxy-oxonia-Cope reaction: synthesis and olfactory properties of new macrocyclic musks.
PubMed:Protective effects of muscone on ischemia-reperfusion injury in cardiac myocytes.
PubMed:Fragrance material review on 3-methyl-1-cyclopentadecanone.
PubMed:Catalytic asymmetric Michael reactions of α,β-unsaturated ketones with sulfonyl-containing nucleophiles: chiral synthesis of (R)-muscone and (S)-celery ketone.
PubMed:Dynamic octopus amphiphiles as powerful activators of DNA transporters: differential fragrance sensing and beyond.
PubMed:Synthesis of omega-hydroxy carboxylic acids and alpha,omega-dimethyl ketones using alpha,omega-diols as alkylating agents.
PubMed:(+)-(R,Z)-5-Muscenone and (-)-(R)-muscone by enantioselective aldol reaction and Grob fragmentation.
PubMed:[Protective effects and machanism of muskone on pheochromocytoma cell injure induced by glutamate].
PubMed:Muscone protects vertebral end-plate degeneration by antiinflammatory property.
PubMed:Efficient formation of ring structures utilizing multisite activation by indium catalysis.
PubMed:Comparison of the therapeutic effects of different compositions of muskone in the treatment of experimental myocardial infarct in rats and analgesia in mice.
PubMed:Synthesis of l-muscone by asymmetric methylation via enol esters.
PubMed:Synthetic applications of enantioselective protonation and case study for (S)-alpha-damascone.
PubMed:A three-carbon (n+1+2) ring expansion method for the synthesis of macrocyclic enones. Application to muscone synthesis.
PubMed:[Effects of series of Muskone on heart hemodynamics and myocardial consumption of oxygen in experimental dogs].
PubMed:[Study on therapeutic effects of series of muskone on myocardial infarction canines].
PubMed:Enantioselective intramolecular aldol addition/dehydration reaction of a macrocyclic diketone: synthesis of the musk odorants (R)-muscone and (R,Z)-5-muscenone.
PubMed:[Study on comparative pharmacology of series of Muskone].
PubMed:Normal-phase chiral liquid chromatography-mass spectrometry of non-UV-active compounds: applications for pharmaceutically relevant racemates.
PubMed:[Determination of muscone in Xingnaojing injection by gas chromatography with solid phase microextraction].
PubMed:CpRu(PN) complex-catalyzed isomerization of allylic alcohols and its application to the asymmetric synthesis of muscone.
PubMed:Ti-crossed-Claisen condensation between carboxylic esters and acid chlorides or acids: a highly selective and general method for the preparation of various beta-keto esters.
PubMed:[Study of diffusion of muscone in different inclusion complexes and liposome through mouse (correction of rat) skin in vitro].
PubMed:Characterization of allegedly musk-containing medicinal products in Taiwan.
PubMed:[An experimental study on distribution of musk into the brain through blood brain barrier].
PubMed:Solid-phase extraction of L-muscone from aqueous samples with Amberlite XAD-4 for gas chromatographic assay.
PubMed:Psychological effects of musky compounds: comparison of androstadienone with androstenol and muscone.
PubMed:Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.
PubMed:Synthesis of (R)- and (S)- muscone.
PubMed:Solid phase synthesis of complex natural products and libraries thereof.
PubMed:Enantioselectivity of the musk odor sensation.
PubMed:[Quantitative analysis of muscone in shexiang baoxin pills by gas chromatography].
PubMed:[Pharmacokinetics of muscone in rats, rabbits and dogs].
PubMed:[Determination of major volatile components in suhexiang wan (storax pill) using analytical supercritical fluid extraction (SFE)].
PubMed:[A preliminary research on the quality of musk].
PubMed:Characterization of liver microsomal cytochrome P450 from rats treated with muscone (3-methylcyclopentadecanone).
PubMed:[Analysis of musk rheumatic oil by GC/FTIR].
PubMed:[Method of analysis for musk, artificially bred musk and original musk by HPLC].
PubMed:Induction of cytochrome P-450 and related drug-oxidizing activities in muscone (3-methylcyclopentadecanone)-treated rats.
PubMed:[Determination of muscone contents in Chinese drug preparations containing Moschus by the TLC scanning method].
PubMed:Musk deer (Moschus moschiferus): Reinvestigation of main lipid components from preputial gland secretion.
PubMed:Pharmacological properties of musk.
PubMed:Induction of rat liver microsomal cytochrome P-450 by muscone (3-methylcyclopentadecanone).
PubMed:[Mass spectrography analysis on the components of a substance obtained from the male musk-rat].
PubMed:[Quantitative analysis of muscone in musk by GC].
PubMed:[The analysis of synthetic muscone (DL-3-methylcyclopentadecanone) and its impurities (author's transl)].
PubMed:Insect and mammalian pheromones.
PubMed:Many-membered carbon rings; a new synthesis of civetone and dl-muscone.
PubMed:[Not Available].
 
Notes:
Incredible fixer. Flavouring ingredient Muscone is an organic compound that is the primary contributor to the odor of musk.
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy