EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

2-isobutyl thiazole
2-isobutylthiazole

Supplier Sponsors

Flavor Demo Formulas
Name:2-(2-methylpropyl)-1,3-thiazole
CAS Number: 18640-74-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:242-470-1
FDA UNII:7N03TDY75D
Nikkaji Web:J45.613F
MDL:MFCD00005334
CoE Number:11618
XlogP3-AA:2.60 (est)
Molecular Weight:141.23667000
Formula:C7 H11 N S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1034 2-isobutylthiazole
FLAVIS Number:15.013 (Old)
DG SANTE Food Flavourings:15.013 2-isobutylthiazole
FEMA Number:3134 2-isobutylthiazole
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.99500 to 0.99530 @ 25.00 °C.
Pounds per Gallon - (est).: 8.279 to 8.282
Specific Gravity:1.00000 to 1.00400 @ 20.00 °C.
Pounds per Gallon - est.: 8.331 to 8.364
Refractive Index:1.49400 to 1.49800 @ 20.00 °C.
Refractive Index:1.49000 to 1.49900 @ 20.00 °C.
Boiling Point: 174.00 to 180.00 °C. @ 760.00 mm Hg
Vapor Pressure:1.091000 mmHg @ 25.00 °C. (est)
Vapor Density:4.8 ( Air = 1 )
Flash Point: 135.00 °F. TCC ( 57.22 °C. )
logP (o/w): 1.715 (est)
Soluble in:
 alcohol
 water, 255.2 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 stable in most media
 
Organoleptic Properties:
Odor Type: green
Odor Strength:high ,
recommend smelling in a 0.10 % solution or less
Substantivity: > 1 hour(s) at 100.00 %
green wasabi privet tomato leaf earthy vegetable metallic
Odor Description:at 1.00 % in dipropylene glycol. green wasabi privet tomato leaf earthy vegetable metallic
Luebke, William tgsc, (2009)
Odor sample from: R C Treatt and Co Ltd
green vegetable musty waxy
Odor Description:Green, vegetable, musty with a waxy nuance
Mosciano, Gerard P&F 17, No. 4, 33, (1992)
Flavor Type: green
green vegetable tomato raw musty
Taste Description: at 2.00 ppm. Green, vegetable, tomato-like with raw musty nuances
Mosciano, Gerard P&F 17, No. 4, 33, (1992)
Odor and/or flavor descriptions from others (if found).
Frutarom
2-ISOBUTYLTHIAZOLE
Odor Description:Fresh, Green, Tomato, Vinous
Suggested Uses: Mushroom, Soft Fruits, Tomato, Tropical Fruits, Vegetables
Taste Description:green vegetable tomato raw musty
R C Treatt & Co Ltd
2-Isobutylthiazole Halal, Kosher
Odor Description:Green tomato leaf
Odor threshold in water: 2-3.5 ppb.
Taste Description:Green tomato
Effective in enhancing tomato juice at 25-50 ppb. Useful for enhancing Tomato flavor of condiments (e.g., Ketchup). This compound is essential to the flavor of Tomato. Normal use levels in finished consumer product: 0.02-1.0 ppm.
Pell Wall Perfumes
Isobutylthiazole
Odor Description:Green, tomato, earthy, vegetable, metallic. Extremely powerful
A very interesting material that, when sufficiently diluted gives an extremely realistic note of tomatoes with the addition of other components it can easily be pushed in the direction of ripe tomato fruits or that characteristic smell of the tomato plant itself.
Perfumery Laboratory
Tomato leaf thiazol 0.1% in DPG PFW (Tomato leaf thiazole 0.1% PFW)
Odor Description:Powerful, fresh, natural, tomato, earthy
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Advanced Biotech
2-ISOBUTYL THIAZOLE NATURAL
Advanced Biotech
2-ISOBUTYL THIAZOLE
Odor: Tomato leaf
Advanced Biotech
ISO BUTYL THIAZOLE 1% ETOH NATURAL
Advanced Biotech
ISOBUTYL THIAZOLE 1% WS NATURAL
Odor: Tomato leaf
Ambles Nature et Chimie
2-ISOBUTYL THIAZOLE
Anhui Suzhou Jinli Aromatic Chemicals
2-isoButyl Thiazole
Odor: tomato
Augustus Oils
2 Iso Butyl Thiazole
Services
Beijing Lys Chemicals
2-isoButylthiazole
BOC Sciences
For experimental / research use only.
2-isoButyl Thiazole 98%
Charkit Chemical
ISOBUTYLTHIAZOLE, 2- 1% IN DPG
Charkit Chemical
ISOBUTYLTHIAZOLE, 2- FEMA 3134
DeLong Chemicals America
2-Isobutylthiazole, Kosher
Endeavour Specialty Chemicals
2-Isobutylthiazole 97% F&F
Speciality Chemical Product Groups
Ernesto Ventós
2-isoBUTYLTHIAZOLE
Odor: TOMATO LEAVES, MUSHROOM, EARTHY
Frutarom
2-ISOBUTYLTHIAZOLE
Odor: Fresh, Green, Tomato, Vinous
Use: Suggested Uses: Mushroom, Soft Fruits, Tomato, Tropical Fruits, Vegetables
Indukern F&F
2-ISOBUTYL THIAZOLE
Odor: GREEN TOMATO LEAF, WOODY
Jiangyin Healthway
2-IsoButyl Thiazole
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-isoButyl thiazole, Kosherk
Kingchem Laboratories
2-ISOBUTYLTHIAZOLE
Odor: Tomato-like
Lluch Essence
2-isoBUTYL THIAZOLE
Odor: WOODY, TOMATO-LEAF NOTES
M&U International
2-isoBUTYL THIAZOLE, Kosher
Natural Advantage
Isobutylthiazole Nat, 1% in Neobee
Flavor: green, musky, tomato
Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries
Natural Advantage
Isobutylthiazole Nat, 1% in OH
Flavor: green, musky, tomato
Natural Advantage
Isobutylthiazole Nat, 1% in PG
Flavor: green, musky, tomato
Natural Advantage
Isobutylthiazole Nat, 10% in Triacetin Nat USOC
Flavor: green, musky, tomato
Natural Advantage
Isobutylthiazole Nat, 10% in Triacetin
Flavor: green, musky, tomato
Natural Advantage
Isobutylthiazole
Flavor: green, musky, tomato
PCW France
Thiazyl 1% DPG
Steps to a fragranced product
Pearlchem Corporation
2-isoButyl Thiazole
Pell Wall Perfumes
Isobutylthiazole
Odor: Green, tomato, earthy, vegetable, metallic. Extremely powerful
Use: A very interesting material that, when sufficiently diluted gives an extremely realistic note of tomatoes with the addition of other components it can easily be pushed in the direction of ripe tomato fruits or that characteristic smell of the tomato plant itself.
Penta International
2-ISOBUTYL THIAZOLE
Penta International
2-ISOBUTYLTHIAZOLE NATURAL
Perfumery Laboratory
Tomato leaf thiazol 0.1% in DPG PFW (Tomato leaf thiazole 0.1% PFW)
Odor: Powerful, fresh, natural, tomato, earthy
R C Treatt & Co Ltd
2-Isobutylthiazole 1% in DPG
Kosher
R C Treatt & Co Ltd
2-Isobutylthiazole
Halal, Kosher
Odor: Green tomato leaf
Use: Odor threshold in water: 2-3.5 ppb.
Flavor: Green tomato
Effective in enhancing tomato juice at 25-50 ppb. Useful for enhancing Tomato flavor of condiments (e.g., Ketchup). This compound is essential to the flavor of Tomato. Normal use levels in finished consumer product: 0.02-1.0 ppm.
Reincke & Fichtner
2-isoButylthiazole
Riverside Aromatics
2-isoBUTYLTHIAZOLE NATURAL 1% IN PG
Riverside Aromatics
2-isoBUTYLTHIAZOLE
Robinson Brothers
2-IsoButylthiazole F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
2-isoButylthiazole
Sigma-Aldrich
2-Isobutylthiazole, ≥99%, FG
Odor: green; vegetable
Certified Food Grade Products
SRS Aromatics
THIAZYL 1% DPG
Sunaux International
2-isoButyl Thiazole
Synerzine
2-isobutylthiazole
nick-named Tomato Leaf Thiazole
Synerzine
natural 2-isoButyl Thiazole
Taytonn
2-isoButylthiazole
Odor: Vinous, Green, Fresh, Tomato
TCI AMERICA
For experimental / research use only.
2-isoButylthiazole >97.0%(GC)
Tengzhou Jitian Aroma Chemiclal
2-isoButyl Thiazole
Tengzhou Xiang Yuan Aroma Chemicals
2-isoButyl Thiazole
The John D. Walsh Company
Thiazyl 1% in DPG
Tianjin Danjun International
2-Isobutylthiazole
Vigon International
Isobutyl-2 Thiazole
Odor: GREEN, NUTTY
WholeChem
2-Isobutyl thiazole
Wujiang CIYUN Flavor & Fragrance
2-isoButyl Thiazole ≥98.0%
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
Recommendation for 2-isobutyl thiazole usage levels up to:
  0.0800 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 3.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.40 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
 average usual ppmaverage maximum ppm
baked goods: -1.00000
beverages(nonalcoholic): -1.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.00000
fruit ices: -1.00000
gelatins / puddings: -1.00000
granulated sugar: --
gravies: -1.00000
hard candy: -1.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -1.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: -1.00000
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -1.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 21: Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29. Miscellaneous substances from chemical group 30. (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 76, (FGE.76)[1] - Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29, miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 21, Revision 1 (FGE.21Rev1): Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 Miscellaneous substances from chemical group 30
View page or View pdf

Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 76, Revision 1 (FGE.76Rev1): Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21Rev3
View page or View pdf

Safety and efficacy of thiazoles, thiophene and thiazoline belonging to chemical group 29 when used as flavourings for all animal species
View page or View pdf

EPI System: View
EPA Substance Registry Services (TSCA):18640-74-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :62725
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1993
WGK Germany:3
2-(2-methylpropyl)-1,3-thiazole
Chemidplus:0018640749
RTECS:XJ5103412 for cas# 18640-74-9
 
References:
 2-(2-methylpropyl)-1,3-thiazole
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:18640-74-9
Pubchem (cid):62725
Pubchem (sid):135021306
Flavornet:18640-74-9
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB31862
FooDB:FDB008546
YMDB (Yeast Metabolome Database):YMDB01585
Export Tariff Code:2934.10.0090
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
alliaceous
dibutyl sulfide
FL/FR
dipropyl disulfide
FL/FR
amber
amber furan
FR
balsamic
tetrahydrofurfuryl cinnamate
FL/FR
caramellic
2-iso
butyl-3-methyl pyrazine
FL/FR
cheesy
S-(
methyl thio) butyrate
FL/FR
chocolate
2,4,5-
trimethyl thiazole
FL/FR
citrus
methyl heptenone
FL/FR
petitgrain combava oil
FR
coumarinic
phthalide
FL/FR
ethereal
2-
methyl valeraldehyde
FL/FR
fatty
2-
nonenal
FL/FR
(E)-2-
octenal
FL/FR
floral
allyl anthranilate
FL/FR
geranium dihydropyran
FR
methyl dihydrojasmonate
FL/FR
bitter
orangeflower absolute morocco
FL/FR
petitgrain lemon oil
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR
laevo-
rose oxide
FL/FR
(Z)-
rose oxide
FL/FR
fruity
2-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-ol
FL/FR
hexyl acetate
FL/FR
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR
iso
butyl methyl ketone
FL/FR
cortex pyridine
FL/FR
cumin acetaldehyde
FL/FR
3,5,6-neo
cyclocitral
FR
diphenyl oxide
FL/FR
galbanum decatriene
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
geranium thiazole
FL/FR
1-
hepten-3-ol
FL/FR
heptyl cinnamate
FL/FR
3-
hexen-1-ol
FL/FR
(Z)-2-
hexen-1-ol
FL/FR
(Z)-4-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl benzoate
FL/FR
(Z)-3-
hexen-1-yl lactate
FL/FR
(Z)-3-
hexen-1-yl methyl carbonate
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
3-
hexenal
FL/FR
hexoxyacetaldehyde dimethyl acetal
FR
hexyl heptanoate
FL/FR
(Z)-
leaf acetal
FL/FR
leafy acetal
FL/FR
leafy oxime
FR
methyl heptine carbonate
FL/FR
narcissus flower absolute
FR
nerol oxide
FL/FR
(Z,Z)-3,6-
nonadien-1-ol
FL/FR
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR
(Z)-5-
octen-1-yl propionate
FL/FR
1-
penten-3-ol
FL/FR
2-
pentenal
FL/FR
(E)-2-
pentenal
FL/FR
phenoxyacetaldehyde 50% in benzyl alcohol
FR
3-
phenyl propionaldehyde
FL/FR
iso
propyl phenyl propionaldehyde
FR
rose leaf absolute (rosa centifolia)
FL/FR
styralyl acetate
FL/FR
herbal
anthemis nobilis flower oil roman
FL/FR
sweet
basil absolute
FL/FR
3-
butylidene phthalide
FL/FR
iso
dihydrolavandulal
FL/FR
herbal heptane
FR
rosemary oleoresin
FL/FR
minty
iso
pulegyl formate
FL/FR
musty
cocoa butenal
FL/FR
nutty
shoyu pyrazine
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
pine
plectranthus glandulosus hook f. leaf oil cameroon
FR
sulfurous
dimethyl sulfide
FL/FR
ethyl methyl mercaptopropionate
FL/FR
methyl 3-(methyl thio) propionate
FL/FR
3-(
methyl thio) hexanol
FL/FR
tomato
tomato essence
FL/FR
tomato specialty
FR
vegetable
methional
FL/FR
woody
alpha-
farnesene
FL/FR
alpha-
farnesene isomer
FL/FR
yeasty
2-
octen-4-one
FL/FR
For Flavor
No flavor group found for these
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
allyl anthranilate
FL/FR
2-
ethyl-4,5-dimethyl oxazole
FL
heptyl cinnamate
FL/FR
3-
hexen-1-ol
FL/FR
2-
hexenal
FL
(E)-2-
hexenal
FL
hexyl heptanoate
FL/FR
3-
methyl-3-pentanol
FL
2-
pentenal
FL/FR
iso
pulegyl formate
FL/FR
tetrahydrofurfuryl cinnamate
FL/FR
alliaceous
alliaceous
allyl thiopropionate
FL
dipropyl disulfide
FL/FR
aromatic
leafy acetal
FL/FR
celery
3-
butylidene phthalide
FL/FR
citrus
petitgrain lemon oil
FL/FR
coumarinic
phthalide
FL/FR
creamy
gamma-
undecalactone (aldehyde C-14 (so-called))
FL/FR
fatty
(Z)-3-
hexen-1-yl benzoate
FL/FR
1-
methyl thio-3-octanone
FL
2-
nonenal
FL/FR
(E)-2-
octenal
FL/FR
fermented
methyl thio isovalerate
FL
floral
methyl dihydrojasmonate
FL/FR
bitter
orangeflower absolute morocco
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR
laevo-
rose oxide
FL/FR
fruity
2,4-
hexadien-1-ol
FL
2-
hexen-1-ol
FL/FR
hexyl acetate
FL/FR
styralyl acetate
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR
iso
butyl methyl ketone
FL/FR
2-iso
butyl-3-methyl pyrazine
FL/FR
cocoa butenal
FL/FR
cortex pyridine
FL/FR
cumin acetaldehyde
FL/FR
dibutyl sulfide
FL/FR
dihydroxyacetophenone (mixed isomers)
FL
diphenyl oxide
FL/FR
alpha-
farnesene
FL/FR
alpha-
farnesene isomer
FL/FR
galbanum decatriene
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
geranium thiazole
FL/FR
1-
hepten-3-ol
FL/FR
(Z)-2-
hexen-1-ol
FL/FR
(Z)-4-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl lactate
FL/FR
(Z)-3-
hexen-1-yl methyl carbonate
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
3-
hexenal
FL/FR
2-
hexyl pyridine
FL
horseradish oil
FL
(Z)-
leaf acetal
FL/FR
methyl heptenone
FL/FR
methyl heptine carbonate
FL/FR
4-
methyl thiazole
FL
nerol oxide
FL/FR
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR
(Z)-5-
octen-1-yl propionate
FL/FR
4-
penten-1-yl acetate
FL
1-
penten-3-ol
FL/FR
(E)-2-
pentenal
FL/FR
3-
phenyl propionaldehyde
FL/FR
propylene glycol acetone ketal
FL
rose leaf absolute (rosa centifolia)
FL/FR
(Z)-
rose oxide
FL/FR
herbal
anthemis nobilis flower oil roman
FL/FR
sweet
basil absolute
FL/FR
iso
dihydrolavandulal
FL/FR
rosemary oleoresin
FL/FR
metallic
2,5-
dihydroxy-1,4-dithiane
FL
3-(
methyl thio) hexanol
FL/FR
musty
S-(
methyl thio) butyrate
FL/FR
shoyu pyrazine
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
nutty
2,4,5-
trimethyl thiazole
FL/FR
onion
methyl propyl disulfide
FL
sulfurous
dimethyl sulfide
FL/FR
ethyl methyl mercaptopropionate
FL/FR
ethyl methyl sulfide
FL
potato butanone
FL
tomato
methional
FL/FR
tomato essence
FL/FR
vegetable
methyl 3-(methyl thio) propionate
FL/FR
2-
methyl valeraldehyde
FL/FR
2-
octen-4-one
FL/FR
potato butyraldehyde
FL
radish isothiocyanate
FL
waxy
(Z,Z)-3,6-
nonadien-1-ol
FL/FR
 
Potential Uses:
FRapricot
FRearth
FRfloral
FRfungus
FRgreen
 leaf
FRmusk
FRpeach
FLtomato
FRtomato leaf
FLvegetable
 vine
 
Occurrence (nature, food, other):note
 cantaloupe fruit
Search Trop Picture
 tomato
Search Trop Picture
 
Synonyms:
2-isobutyl-1,3-thiazole
isobutyl-2 thiazole
2-isobutylthiazole
isobutylthiazole
2-(2-methyl propyl) thiazole
2-(2-methylpropyl)-1,3-thiazole
2-(2-methylpropyl)thiazole
 thiazole, 2-(2-methylpropyl)-
 thiazole, 2-isobutyl-
 thiazyl (PFW)
 thiazyl 1% DPG (PFW)
 thiazyl 1% in DPG (PFW)
 tomato leaf thiazole
 

Articles:

PubMed:Impact of different distribution scenarios and recommended storage conditions on flavor related quality attributes in ripening fresh tomatoes.
PubMed:Dynamics of odorant binding to thin aqueous films of rat-OBP3.
PubMed:Flavor release of the tomato flavor enhancer, 2-isobutylthiazole, from whey protein stabilized model dressings.
PubMed:Population pharmacokinetic model for a novel oral hypoglycemic formed in vivo: comparing the use of active metabolite data alone versus using data of upstream and downstream metabolites.
PubMed:Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.
PubMed:Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells.
PubMed:P2Y2 receptor-Gq/11 signaling at lipid rafts is required for UTP-induced cell migration in NG 108-15 cells.
PubMed:Comparison of tomatillo and tomato volatile compounds in the headspace by selected ion flow tube mass spectrometry (SIFT-MS).
PubMed:The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor.
PubMed:Studies on the aroma of five fresh tomato cultivars and the precursors of cis- and trans-4,5-epoxy-(E)-2-decenals and methional.
PubMed:A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo.
PubMed:MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.
PubMed:Nitric oxide donating nonsteroidal anti-inflammatory drugs induce apoptosis in human prostate cancer cell systems and human prostatic stroma via caspase-3.
PubMed:First synthesis of an amythiamicin pyridine cluster.
PubMed:Absolute configuration of 2-sec-butyl-4,5-dihydrothiazole in male mouse urine.
PubMed:CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
PubMed:Differential effects of tomato (Lycopersicon esculentum mill) matrix on the volatility of important aroma compounds.
PubMed:Addition of heteroaromatics to alkylidenecyclopropanes catalyzed by palladium.
PubMed:Odorants of different chemical classes interact with distinct odorant binding protein subtypes.
PubMed:Synthesis and dopamine receptor modulating activity of substituted bicyclic thiazolidine lactam peptidomimetics of L-prolyl-L-leucyl-glycinamide.
PubMed:Mammalian pheromones VIII Chemical characterization of preorbital gland secretion of grey duiker,Sylvicapra grimmia (Artiodactyla: Bovidae).
PubMed:Mammalian pheromone studies, VII. Identification of thiazole derivatives in the preorbital gland secretions of the grey duiker, Sylvicapra grimmia, and the red duiker, Cephalophus natalensis.
PubMed:The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.
 
Notes:
isolated from preorbital gland of the grey duiker, sylvicapra grimmia and the red duiker, cephalophus natalensis. Tomato volatile and flavouring ingredient. Liq. with tomato leaf odour
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