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valeriana officinalis root extract
extract of the roots from the valerian, valeriana officinalis l., valerianaceae

Supplier Sponsors

Name:valeriana officinalis l. root extract
CAS Number: 8057-49-6
ECHA EC Number:232-501-7
Wisconsin Invasive Non-native plant species
Category:cosmetic, flavor and fragrance agents, dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Perfumer and Flavorist:Search
Google Patents:Search
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PubMed:Search
NCBI:Search
FEMA Number:3099 valerian root extract
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: VALERIAN ROOT, EXTRACT (VALERIANA OFFICINALIS L.)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
 
Physical Properties:
Appearance:brown liquid (est)
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor Type: fruity
Odor Strength:medium
Substantivity:12 Hour(s)
sweet woody dry powdery musk amber
Odor Description:at 100.00 %. sweet woody dry powdery musky amber
Flavor Type: fruity
valerian root
Taste Description: valerian root
Odor and/or flavor descriptions from others (if found).
Frutarom
VALERIAN ROOT SE FR
Taste Description:Balsamic, Herbal, Green, Acidic, Cheesy
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
Amax Nutrasource
Valerian Root 0.8% Valerenic Acid; 4:1 Extract
Astral Extracts
Valerian Root Extract
AuNutra® Industries
Valerian Root P.E.
Bell Flavors & Fragrances
Valerian Extract Natural
Bio-Botanica®
Valerian Root Valeriana Officinalis Root Extract
Bio-Botanica®
Valerian, AF – 5560
Bio-Botanica®
Valerian, FE – 5149
Bio-Botanica®
Valerian, SE – 2139
Carrubba
valerian root extract
Frutarom
VALERIAN ROOT FE 61-68% ALC
Frutarom
VALERIAN ROOT SE FR
Flavor: Balsamic, Herbal, Green, Acidic, Cheesy
Grau Aromatics
VALERIAN EXTRACT HS 2396 G
(hydrosoluble)
Grau Aromatics
VALERIAN EXTRACT LS 3086 G
(liposoluble)
Jiangyin Healthway
Valerian Root
New functional food ingredients
Lipotec USA
Actiphyte® of Valerian Root Extract
Naturex
Valerian Extract
NAT arom®, liquid or powder forms
Naturex
Valerian Root Extract Deodorized
NATpharma™
Odor: characteristic
Use: Application: Mental stress, Nervous tension, Sleep disorders
Naturex
Valerian Root Extract
NATpharma™
Odor: characteristic
Use: Application: Mental stress, Nervous tension, Sleep disorders
Penta International
VALERIAN ROOT FLUID EXTRACT
Penta International
VALERIAN ROOT SOLID EXTRACT, Kosher
SRS Aromatics
VALERIAN EXTRACT HS 2396 G
SRS Aromatics
VALERIAN EXTRACT LS 3086 G
Vege Tech
Organic Valerian Root Extract
Xian Yuensun Biological Technology
Valerian Root Extract, Valeric Acid 0.4% 0.8%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 3300 mg/kg
KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Journal of Pharmaceutical Sciences. Vol. 50, Pg. 240, 1961.

intraperitoneal-mammal (species unspecified) LD50 975 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988.

oral-mammal (species unspecified) LD50 2250 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic, flavor and fragrance agents, dietary supplements
Wisconsin Invasive Non-native plant species
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -69.00000
beverages(nonalcoholic): -25.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -24.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -35.00000
fruit ices: -35.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -65.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
ClinicalTrials.gov:search
Daily Med:search
NLM Hazardous Substances Data Bank:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
NLM Developmental and Reproductive Toxicity:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
valeriana officinalis l. root extract
Chemidplus:0008057496
 
References:
 valeriana officinalis l. root extract
Pubchem (sid):135331255
 
Other Information:
FDA Everything Added to Food in the United States (EAFUS):View
Export Tariff Code:1302.19.0000
Wikipedia:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
amber romance fragrance
FR
(Z)-iso
ambrettolide
FR
amber
amber
amber acetate
FR
amber cyclohexanol
FR
amber spirolene
FR
ambergris specialty
FR
ambergris tincture
FL/FR
ambrette seed absolute
FL/FR
ambrette seed oil
FL/FR
ambrette seed oil CO2 extract
FL/FR
ambrette seed oil replacer
FR
(cis+trans)-6,6a,7,8,9,9a-
hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
FR
muscomer
FR
animal
2-
methyl-4-(camphenyl-8) cyclohexanone
FR
aromatic
(4E,9Z)-13-
methyloxacyclopentadeca-4,9-dien-2-one
FR
balsamic
1-
benzoyl acetone
FL/FR
valerian rhizome absolute
FL/FR
valeriana wallichii root oil
FR
bitter
gentian absolute
FL/FR
citrus
bitter
orange peel oil
FL/FR
floral
floral undecenone
FR
(E)-beta-
ionone
FL/FR
iso
jasmone
FL/FR
primrose fragrance
FR
fruity
cyclohexyl anthranilate
FL/FR
1-(3,3-
dimethyl bicyclo(2.2.1)hept-2-yl)-2-methyl cyclohex-3-ene carbaldehyde
FR
valerian rhizome essence
FL/FR
valeriana officinalis rhizome extract
FL/FR
valeriana officinalis rhizome tincture
FL/FR
valeriana officinalis rhizome/root extract
FL/FR
green
3-
hexenyl isovalerate
FL/FR
methyl cyclocitrone (IFF)
FR
oakmoss oil
FR
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
valerian rhizome oil CO2 extract china
FL/FR
herbal
(-)-
bornyl isovalerate
FL/FR
clary sage oil france
FL/FR
clary specialty
FR
white
cognac oil
FL/FR
herbal carene
FR
hop absolute
FL/FR
lavandin water absolute
FL/FR
laevo-beta-
pinene
FL/FR
beta-
pinene
FL/FR
valerian rhizome oil
FL/FR
valerian rhizome oil china
FL/FR
mossy
treemoss absolute
FR
musk
dehydro beta-linalool
FL/FR
ethylene brassylate
FL/FR
exaltone (Firmenich)
FR
juniper muscone
FR
moskene (Givaudan)
CS
musk amberol
FR
musk ether
FR
musk indane
FR
musk lactone
FR
musk methyl ketone
FR
musk tetralin
FR
musk tibetene (Givaudan)
CS
6,7,8,9-
tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
FR
powdery
baby powder fragrance
FR
midnight passion fragrance
FR
spicy
beta-
caryophyllene
FL/FR
saffron oil CO2 extract
FL/FR
woody
acetyl cedrene
FR
iso
bornyl isovalerate
FL/FR
beta-
caryophyllene alcohol acetate
FL/FR
atlas
cedarwood absolute
FR
atlas
cedarwood oil
FR
cedarwood oil alcohols
FL/FR
cedrela wood oil
FR
cedrenyl acetate
FR
cedrol methyl ether
FR
2-
decalinyl formate
FR
guaiene
FL/FR
hinoki root oil
FR
hydroxyambran
FR
labdanum concrete
FR
labdanum ethanone
FR
louro brasileiro wood oil
FR
para-
menth-3-en-1-ol
FL/FR
2-
methoxy-4-vinyl phenol
FL/FR
methyl vetivate
FR
patchouli ethanone
FR
patchouli fractions
FR
sandalwood oil west australia (santalum spicatum)
FR
(+)-alpha-
santalyl acetate
FL/FR
spikenard oil
FL/FR
spikenard oil CO2 extract
FL/FR
thujopsis dolabrata wood oil
FR
woody dioxolane
FR
woody ether
FR
woody propanol
FR
For Flavor
No flavor group found for these
ambergris tincture
FL/FR
1-
benzoyl acetone
FL/FR
(-)-
bornyl isovalerate
FL/FR
beta-
caryophyllene alcohol acetate
FL/FR
cedarwood oil alcohols
FL/FR
dehydro beta-linalool
FL/FR
gentian absolute
FL/FR
para-
menth-3-en-1-ol
FL/FR
menthyl valerate
FL
laevo-beta-
pinene
FL/FR
(+)-alpha-
santalyl acetate
FL/FR
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
spikenard oil
FL/FR
spikenard oil CO2 extract
FL/FR
amber
amber
ambrette seed oil
FL/FR
ambrette seed oil CO2 extract
FL/FR
citrus
bitter
orange peel oil
FL/FR
fruity
cyclohexyl anthranilate
FL/FR
valerian rhizome absolute
FL/FR
valerian rhizome distillates
FL
valerian rhizome essence
FL/FR
valerian rhizome oil
FL/FR
valerian rhizome oil china
FL/FR
valerian rhizome oil CO2 extract china
FL/FR
valeriana officinalis rhizome extract
FL/FR
valeriana officinalis rhizome tincture
FL/FR
valeriana officinalis rhizome/root extract
FL/FR
fusel
white
cognac oil
FL/FR
green
3-
hexenyl isovalerate
FL/FR
iso
jasmone
FL/FR
herbal
clary sage oil france
FL/FR
hop absolute
FL/FR
lavandin water absolute
FL/FR
musk
ethylene brassylate
FL/FR
phenolic
2-
hydroxyisophorone
FL
pine
beta-
pinene
FL/FR
powdery
powdery ketone
FL
smoky
2-
methoxy-4-vinyl phenol
FL/FR
spicy
beta-
caryophyllene
FL/FR
saffron oil CO2 extract
FL/FR
woody
ambrette seed absolute
FL/FR
iso
bornyl isovalerate
FL/FR
guaiene
FL/FR
(E)-beta-
ionone
FL/FR
 
Potential Uses:
FRamber
FRbalsam
FRchypre
FRleather
FRleather russian leather
FRmoss
FRmusk
FRtobacco
FRwoody
 
Occurrence (nature, food, other):note
 valerian
Search Trop Picture
 
Synonyms:
 extract of the roots from the valerian, valeriana officinalis l., valerianaceae
 valerian extract
 valerian extract HS 2396 G (Grau)
 valerian extract LS 3086 G (Grau)
 valerian extract natural
 valerian root 0.8% valerenic acid; 4:1 extract
 valerian root extract
actiphyte of valerian root extract
 valerian root extract deodorized
 valerian root fluid extract
 valerian root P.E.
 valerian root solid extract
 

Articles:

PubMed:Valeriana officinalis root extract suppresses physical stress by electric shock and psychological stress by nociceptive stimulation-evoked responses by decreasing the ratio of monoamine neurotransmitters to their metabolites.
PubMed:Can Valeriana officinalis root extract prevent early postoperative cognitive dysfunction after CABG surgery? A randomized, double-blind, placebo-controlled trial.
PubMed:Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation.
PubMed:Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis).
PubMed:Telemetry as a tool to measure sedative effects of a valerian root extract and its single constituents in mice.
PubMed:Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats.
PubMed:Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine.
PubMed:Analysis of responses to valerian root extract in the feline pulmonary vascular bed.
PubMed:(-)-3 beta,4 beta-epoxyvalerenic acid from Valeriana officinalis.
PubMed:Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier.
 
Notes:
Soothing, calmative agent for skin care preparations. Blends well with moss and woody notes.
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