coumarin
 
Notes:
tobacco note - coumarin and myrrh resinoid. effective in reducing edema following crush & thermal injury; coumarin itself occurs in the tonka bean (dipteryx). Occurs in sweet clover. Banned by FDA for use in food Coumarin is a fragrant chemical compound in the benzopyrone chemical class, found in many plants, notably in high concentration in the tonka bean (Dipteryx odorata), vanilla grass (Anthoxanthum odoratum), sweet woodruff (Galium odoratum), mullein (Verbascum spp.), sweet grass (Hierochloe odorata), cassia cinnamon (Cinnamomum aromaticum) and sweet clover (Fabaceae spp.). It has a sweet odor, readily recognised as the scent of newly-mown hay, and has been used in perfumes since 1882. Sweet woodruff, sweet grass and sweet clover in particular are named for their sweet smell, which is due to their high content of this substance. When it occurs in high concentrations in forage plants, coumarin is a somewhat bitter-tasting appetite suppressant, and is presumed to be produced by plants as a defense chemical to discourage predation. Although coumarin itself has no anticoagulant properties, it is transformed into the natural anticoagulant dicoumarol by a number of species of fungi. Coumarin is used in the pharmaceutical industry as a precursor molecule in the synthesis of a number of synthetic anticoagulant pharmaceuticals similar to dicoumarol, the notable ones being warfarin (tradenamed "Coumadin," not to be confused with coumarin) and some even more potent rodenticides that work by the same anticoagulant mechanism. [Wikipedia]
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Fragrance Demo Formulas
Name: chromen-2-one
CAS Number: 91-64-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 202-086-7
FDA UNII:A4VZ22K1WT
Nikkaji Web: J3.218B
Beilstein Number: 0383644
MDL: MFCD00006850
XlogP3: 1.40 (est)
Molecular Weight: 146.14522000
Formula: C9 H6 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Perfumer and Flavorist: Search
Google Patents: Search
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Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm: COUMARIN--PROHIBITED
FDA Regulation:
FDA PART 189 -- SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD
Subpart C--Substances Generally Prohibited From Direct Addition or Use as Human Food
Sec. 189.130 Coumarin.
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Physical Properties:
Appearance: white crystals (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 68.00 to  74.00 °C. @ 760.00 mm Hg
Boiling Point: 297.00 to  301.00 °C. @ 760.00 mm Hg
Boiling Point: 161.00 to  162.00 °C. @ 14.00 mm Hg
Congealing Point: 68.00 °C.
Vapor Pressure: 0.100000 mmHg @ 20.00 °C.
Vapor Density: 5.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.00 °C. )
logP (o/w): 1.390
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 kerosene
 paraffin oil
 water, 1900 mg/L @ 20 °C (exp)
Insoluble in:
 water
 isopropyl myristate
Stability:
 non-discoloring
Similar Items: note
6-amyl-alpha-pyrone
4,6-dimethyl-alpha-pyrone
(±)-dihydromint lactone
tonka ketone
tonka furanone
gamma-hexalactone
tonkavert
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: tonka
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
Odor Description:
at 10.00 % in dipropylene glycol. 
sweet hay tonka new mown hay
Substantivity: 364 hour(s) at 10.00 % in dipropylene glycol
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Safety Information:
Most important hazard(s):
Xn - Harmful.
  R 22 - Harmful if swallowed.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
Oral/Parenteral Toxicity:
  oral-rat LD50  293 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 385, 1974.

oral-mouse LD50  196 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 83, Pg. 1124, 1963.

intraperitoneal-mouse LD50  220 mg/kg
BEHAVIORAL: ANALGESIA
Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 897, 1965.

oral-guinea pig LD50  202 mg/kg
LIVER: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

oral-man TDLo  87 mg/kg/17W-I
LIVER: LIVER FUNCTION TESTS IMPAIRED
Human Toxicology. Vol. 8, Pg. 501, 1989.

Dermal Toxicity:
  subcutaneous-mouse LD50 242 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 83, Pg. 1124, 1963.

Inhalation Toxicity:
  Not determined
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Safety in Use Information:
Category: fragrance agents
IFRA Critical Effect: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.10 % (1)
Category 2:  0.13 %
Category 3:  0.50 %
Category 4:  1.60 %
Category 5:  0.80 %
Category 6:
See Note (1)
2.50 % (1)
Category 7:  0.30 %
Category 8:  2.00 %
Category 9:  5.00 %
Category 10:  2.50 %
Category 11: See Note (2)
 Notes:
 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for coumarin flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Coumarin.
View page or View pdf
Coumarin in flavourings and other food ingredients with flavouring properties - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
EPI System: View
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 91-64-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 323
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WISER: UN 2811
WGK Germany:1
 chromen-2-one
Chemidplus: 0000091645
EPA/NOAA CAMEO:hazardous materials
RTECS: 91-64-5
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References:
 chromen-2-one
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 91-64-5
Pubchem (cid): 323
Pubchem (sid): 134971583
Flavornet: 91-64-5
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C05851
HMDB (The Human Metabolome Database): HMDB01218
FooDB: FDB011938
Export Tariff Code: 2932.21.0000
Haz-Map: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
7-methyl coumarin replacerFR
aldehydic
2-methyl undecanal (aldehyde C-12 mna)FL/FR
amber
 angelica root oilFL/FR
 cistus ladaniferus resinoidFL/FR
 sarcocaulon mossamedense wood resinoidFR
animal
 animal carbolactoneFR
 civet absoluteFL/FR
 costus valerolactoneFR
 indoleFL/FR
anisic
para-anisaldehydeFL/FR
balsamic
 amyris wood oilFL/FR
siam benzoin resinoidFL/FR
 benzyl cinnamateFL/FR
 benzyl salicylateFL/FR
isobutyl cinnamateFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 khella oilFR
 methyl (E)-cinnamateFL/FR
6-methyl coumarin replacerFR
 peru balsam oilFL/FR
black poplar bud oleoresinFL/FR
 styrax resinoid (liquidambar styraciflua)FL/FR
 tolu balsamFL/FR
berry
 raspberry ketoneFL/FR
buttery
 acetoinFL/FR
 ethyl maltolFL/FR
 fenugreek absoluteFL/FR
 immortelle absoluteFL/FR
citrus
 lime oil distilled mexicoFL/FR
 lime oil expressed floridaFL/FR
coconut
 coconut decanone methylFR
 coconut fragranceFR
 coconut specialtyFR
gamma-heptalactoneFL/FR
delta-nonalactoneFL/FR
coumarinic
 coumaneFL/FR
 coumarin replacerFR
 deertongue oilFR
 liatris odoratissima leaf extractFR
coumarin free liatris odoratissima oilFR
 phthalideFL/FR
 tonka bean oilFR
 tonka bean oleoresinFR
 tonka bean resinoidFR
 tonka bean resinoid replacerFR
 tonka bean tinctureFR
 tonka furanoneFL/FR
 tonka ketoneFR
 tonkavertFR
floral
 acetophenoneFL/FR
isoamyl salicylateFL/FR
para-anisyl nitrileFR
 bursera graveolens wood oilFL/FR
isobutyl salicylateFL/FR
 cananga oilFL/FR
 clover fragranceFR
 dihydrojasmoneFL/FR
 floral pyranolFR
 heliotropinFL/FR
 heliotropyl acetoneFL/FR
 heliotropyl diethyl acetalFR
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
 lavender oilFL/FR
 linden flower absoluteFR
 linden flower absolute replacerFR
ortho-methyl acetophenoneFL/FR
para-methyl acetophenoneFL/FR
alpha-naphthyl methyl ketoneFL/FR
 narcissus absolute replacerFR
 nerolidolFL/FR
 ocean propanalFL/FR
 orris rhizome absolute (iris pallida)FL/FR
 palmarosa oilFL/FR
 phenethyl phenyl acetateFL/FR
 tilia cordata flower oil CO2 extractFR
fruity
 benzaldehydeFL/FR
 cherry propanolFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
green
 diphenyl methaneFL/FR
 galbanum oilFL/FR
 heptyl heptanoateFL/FR
 narcissus flower absoluteFR
3-phenyl propionaldehydeFL/FR
 picea glauca leaf absoluteFR
 thuja occidentalis leaf absoluteFR
hay
 hay absoluteFR
 hay concreteFR
 new mown hay fragranceFR
herbal
 apium graveolens seed oil indiaFL/FR
 immortelle flower oilFL/FR
abrialis lavandin oilFL/FR
 linalyl acetateFL/FR
 origanum oil greeceFL/FR
 rosemary oil spainFL/FR
 trigonella foenum-graecum seed extractFL/FR
lactonic
 jasminoneFL/FR
melon
 watermelon ketoneFR
mossy
 flouve oilFR
 oakmoss absoluteFL/FR
 treemoss absoluteFR
 veramoss (IFF)FR
musty
2-acetyl pyrroleFL/FR
naphthyl
beta-naphthyl ethyl etherFL/FR
beta-naphthyl methyl etherFL/FR
nutty
2-acetyl-5-methyl furanFL/FR
phenolic
2'-hydroxyacetophenoneFL/FR
powdery
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
spicy
 benzyl isoeugenolFL/FR
 croton eluteria bark oilFL/FR
 cubeb oilFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale root oilFL/FR
 nutmeg oilFL/FR
black poplar bud absoluteFR
 saffron oil CO2 extractFL/FR
sweet
 tonka bean absolute replacerFR
terpenic
 frankincense oilFL/FR
thujonic
 armoise oilFR
tobacco
 deertongue absolute replacerFR
tonka
 deertongue absoluteFR
 deertongue concreteFR
 deertongue oleoresinFR
 dihydrocoumarin replacerFR
(±)-dihydromint lactoneFL/FR
 flouve absoluteFR
gamma-hexalactoneFL/FR
 melilot absoluteFR
 mint lactoneFL/FR
 octahydrocoumarinFL/FR
 tonka bean absoluteFR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
woody
 guaiacwood oilFL/FR
 methyl cedryl ketoneFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 santallFR
 spruce needle oil canadaFL/FR
 tobacarol (IFF)FR
 vetiver oil haitiFL/FR
 vetiverolFL/FR
 woody acetateFR
(Z)-woody amyleneFR
 woody propanolFR
 
For Flavor
 
No flavor group found for these
 bursera graveolens wood oilFL/FR
 cistus ladaniferus resinoidFL/FR
 coumaneFL/FR
 methyl (E)-cinnamateFL/FR
alpha-naphthyl methyl ketoneFL/FR
black poplar bud oleoresinFL/FR
 tonka furanoneFL/FR
animal
 civet absoluteFL/FR
 indoleFL/FR
anisic
ortho-methyl acetophenoneFL/FR
balsamic
siam benzoin resinoidFL/FR
 benzyl salicylateFL/FR
isobutyl cinnamateFL/FR
 copaiba balsam oilFL/FR
 ethyl cinnamateFL/FR
 peru balsam oilFL/FR
 styrax resinoid (liquidambar styraciflua)FL/FR
 tolu balsamFL/FR
berry
 heliotropyl acetoneFL/FR
 raspberry ketoneFL/FR
bready
 trigonella foenum-graecum seed extractFL/FR
caramellic
 caramel furanoneFL
 ethyl maltolFL/FR
 fenugreek absoluteFL/FR
celery
 jasminoneFL/FR
cherry
 heliotropinFL/FR
citrus
 lime oil distilled mexicoFL/FR
 lime oil expressed floridaFL/FR
coconut
6-methyl coumarinFL
 octahydrocoumarinFL/FR
cooling
isobutyl salicylateFL/FR
coumarinic
 phthalideFL/FR
creamy
 acetoinFL/FR
para-anisaldehydeFL/FR
gamma-hexalactoneFL/FR
para-methyl acetophenoneFL/FR
 mint lactoneFL/FR
delta-nonalactoneFL/FR
floral
 cananga oilFL/FR
 dihydrojasmoneFL/FR
 linalyl acetateFL/FR
 ocean propanalFL/FR
fruity
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
 benzaldehydeFL/FR
 cherry propanolFL/FR
 tolualdehydes (mixed o,m,p)FL/FR
grassy
 palmarosa oilFL/FR
green
isoamyl salicylateFL/FR
 angelica root oilFL/FR
 diphenyl methaneFL/FR
 galbanum oilFL/FR
 heptyl heptanoateFL/FR
 immortelle absoluteFL/FR
 nerolidolFL/FR
 oakmoss absoluteFL/FR
3-phenyl propionaldehydeFL/FR
herbal
 apium graveolens seed oil indiaFL/FR
 immortelle flower oilFL/FR
abrialis lavandin oilFL/FR
 lavender oilFL/FR
 origanum oil greeceFL/FR
 rosemary oil spainFL/FR
honey
 phenethyl phenyl acetateFL/FR
lactonic
(±)-dihydromint lactoneFL/FR
gamma-heptalactoneFL/FR
naphthyl
2'-hydroxyacetophenoneFL/FR
beta-naphthyl methyl etherFL/FR
nutty
2-acetyl pyrroleFL/FR
2-acetyl-5-methyl furanFL/FR
powdery
 acetophenoneFL/FR
beta-naphthyl ethyl etherFL/FR
spicy
 benzyl cinnamateFL/FR
 benzyl isoeugenolFL/FR
 benzylidene acetoneFL
 croton eluteria bark oilFL/FR
 cubeb oilFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale root oilFL/FR
 nutmeg oilFL/FR
 saffron oil CO2 extractFL/FR
sweet
 orris rhizome absolute (iris pallida)FL/FR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
waxy
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
2-methyl undecanal (aldehyde C-12 mna)FL/FR
woody
 amyris wood oilFL/FR
 frankincense oilFL/FR
 guaiacwood oilFL/FR
 methyl cedryl ketoneFL/FR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 spruce needle oil canadaFL/FR
 vetiver oil haitiFL/FR
 vetiverolFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 a suma 
 acaciaFR
 aimant 
 aldehydicFR
 allspiceFR
 almondFR
 amberFR
 ambreneFR
 ambrosiaFR
 angel essenceFR
 apricotFR
 azaleaFR
 baby powderFR
 balsamFR
 bananaFR
 bay rumFR
 bayberryFR
 beeswax absolute replacerFR
 benzoinettFR
 blue grassFR
 blue mistFR
 bluebellFR
 bubble gumFR
 carnationFR
 cassiaFR
 cedarFR
 chanel #5 
 cherryFR
 cherry blossomFR
 chocolate cocoaFL
 christmasFR
 chypreFR
 cloverFR
 coconutFR
 coconut tropical coconutFR
 cologneFR
 coronillaFR
 country meadowFR
 crabapple blossomFR
 deertongue absolute replacerFR
 elder flowerFR
 emeraude 
 erica 
 evergreenFR
 fernFR
 fetesFR
 fir needle oil replacerFR
 fixer 
 floralFR
 frangipani plumeriaFR
 fresh outdoorsFR
 gardeniaFR
 gingerbreadFR
 hawthornFR
 hay new mown hayFR
 heliotropeFR
 herbalFR
 honeysuckleFR
 immortelleFL/FR
 jasminFR
 je reviens 
 jicky 
 juniper berryFR
 lavenderFR
 leather russian leatherFR
 lemonFR
 limeFR
 majaFR
 melonFR
 mimosaFR
 mintFR
 muskFR
 my sin 
 nemesia 
 nutFL
 ophiraFR
 opoponaxFR
 orange blossomFR
 orchidFR
 orientalFR
 origan 
 papayaFR
 passion blossomFR
 pennyroyalFL/FR
 pina coladaFR
 pine forestFR
 poppy red poppyFR
 powderFR
 presence 
 pumpkin pieFR
 rainFR
 sandalwoodFR
 sassafrasFR
 scandal 
 shalimar 
 softener 
 sweet grassFR
 sweet peaFR
 tabu 
 tide 
 tobaccoFR
 tonka beanFR
 tuberoseFR
 valerianFL/FR
 vanillaFR
 violetFR
 vol de nuit 
 wallflowerFR
 windsor soapFR
 wisteriaFR
 woodruffFR
 woodyFR
 ylang ylangFR
 zibelineFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 anise seed
Search Trop  Picture
 apple custard apple plant
Search Trop  Picture
 barley plant
Search Trop  Picture
 bergamot oil @ trace%
Data  GC  Search Trop  Picture
 bilberry fruit - 0.0005 mg/kg
Search Trop  Picture
 cacao bean
Search Trop  Picture
 caper plant
Search Trop  Picture
 carrot root
Search Trop  Picture
 cassia bark
Search Trop  Picture
 cassia leaf oil - up to 83,300 mg /kg
Search Trop  Picture
 celery seed
Search Trop  Picture
 champaca concrete @ 0.01%
Data  GC  Search Trop  Picture
 cherry sour cherry plant
Search Trop  Picture
 chicory plant
Search Trop  Picture
 cichorium intybus l. root extract @ 0.20%
Data  GC  Search Trop  Picture
 cinnamon bark oil - 7000 mg/kg
Search Trop  Picture
 cinnamon bark oil (cinnamomum zeylanicum blume) india @ 0.41%
Data  GC  Search Trop  Picture
 cinnamon ceylon cinnamon bark
Search Trop  Picture
 cinnamon ceylon cinnamon leaf oil
Search Trop  Picture
 cinnamon ceylon cinnamon stem bark
Search Trop  Picture
 cinnamon leaf oil - 40,600 mg/kg
Search Trop  Picture
 cinnamon twig oil @ 0.32%
Data  GC  Search Trop  Picture
 clover yellow sweet clover
Search Trop  Picture
 cocoa bean
Search Trop  Picture
 date palm leaf
Search Trop  Picture
 dill seed
Search Trop  Picture
 fenugreek plant
Search Trop  Picture
 fenugreek seed
Search Trop  Picture
 fig leaf
Search Trop  Picture
 grape fruit
Search Trop  Picture
 honey buckwheat honey
PbMd  Search  PMC Picture
 lavandin absolute grosso @ 7.70%
Data  GC  Search Trop  Picture
 lavandin water (lavandula hydrida) @ 0.08%
Data  GC  Search Trop  Picture
 lavender oil - 20 mg/kg
Search Trop  Picture
 lavender spike water @ 0.06%
Data  GC  Search Trop  Picture
 lavender water bulgaria @ 0.19%
Data  GC  Search Trop  Picture
 lemon plant
Search Trop  Picture
 lovage root
Search Trop  Picture
 mugwort plant
Search Trop  Picture
 peppermint leaf
Search Trop  Picture
 peppermint oil - 20 mg/kg
Search Trop  Picture
 purslane plant
Search Trop  Picture
 tarragon plant
Search Trop  Picture
 tea green tea - 1.2 – 1.7 mg/kg
Search Trop  Picture
 thyme oil
Search Trop  Picture
 tonka bean
Search Trop  Picture
 wormwood wild wormwood plant
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 benzo-alpha-pyrone
2H-benzo(b)pyran-2-one
2H-benzo[b]pyran-2-one
2-oxo-1,2-benzopyran
2-oxo-2H-1-benzopyran
o-oxo-1,2-benzopyran
ortho-oxo-1,2-benzopyran
1-benzopyran-2-one
2H-benzopyran-2-one
2H-1-benzopyran-2-one
2H-1-benzopyran, 2-oxo-
1,2-benzopyrone
 chromen-2-one
2H-chromen-2-one
 chromenone
cis-o-coumaric acid anhydride
 coumarin (ex tonka beans)
 coumarin crystals
 coumarin natural
 coumarin powder 60 mesh
 coumarin, chinese
 coumarin, japan
 coumarine
 coumarine ( ex china )
 coumarine rhodiantal
(Z)-o-coumarinic acid lactone
(Z)-ortho-coumarinic acid lactone
 coumarinic anhydride
 coumarinic lactone
 cumarin
o-hydroxycinnamic acid delta-lactone
ortho-hydroxycinnamic acid delta-lactone
o-hydroxycinnamic acid lactone
ortho-hydroxycinnamic acid lactone
o-hydroxycinnamic lactone
ortho-hydroxycinnamic lactone
3-(2-hydroxyphenyl)-2-propenoic d-lactone
3-(2-hydroxyphenyl)-delta-lactone
2-propenoic acid, 3-(2-hydroxyphenyl)-, d-lactone
2-propenoic acid, 3-(2-hydroxyphenyl)-d-lactone
 tonka bean camphor
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Articles:
PubMed: Effect of flavors on the viscosity and gelling point of aqueous poloxamer solution.
PubMed: Quantification of flavor-related compounds in the unburned contents of bidi and clove cigarettes.
PubMed: Biocatalytic production of dihydrocoumarin from coumarin by Saccharomyces cerevisiae.
PubMed: Determination of volatile flavor components in danggui cultivars by solvent free injection and hydrodistillation followed by gas chromatographic-mass spectrometric analysis.
PubMed: Concentrations of nine alkenylbenzenes, coumarin, piperonal and pulegone in Indian bidi cigarette tobacco.
PubMed: Identification and quantification of aroma-active components that contribute to the distinct malty flavor of buckwheat honey.
PubMed: Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties.
PubMed: Solid phase microextraction of alkenylbenzenes and other flavor-related compounds from tobacco for analysis by selected ion monitoring gas chromatography-mass spectrometry.
PubMed: NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed: Reactions in selected patients to 22 fragrance materials.
PubMed: Full evaporation dynamic headspace and gas chromatography-mass spectrometry for uniform enrichment of odor compounds in aqueous samples.
PubMed: Volatiles of French ferns and "fougère" scent in perfumery.
PubMed: Volatile components of whole and different plant parts of bastard balm (Melittis melissophyllum L., Lamiaceae) collected in Central Italy and Slovakia.
PubMed: Predication of Japanese green tea (Sen-cha) ranking by volatile profiling using gas chromatography mass spectrometry and multivariate analysis.
PubMed: Characterization and potential uses of Copaifera langsdorfii seeds and seed oil.
PubMed: Roles of the mushroom bodies in olfactory learning and photoperiodism in the blow fly Protophormia terraenovae.
PubMed: Metabolism and biochemical effects of nicotine for primary care providers.
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