| 
 Category: flavor and fragrance agents 
  
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: 
  
Physical Properties: 
| Appearance: | colorless clear liquid (est) |  
| Assay: |  94.00 to 100.00 
 |  
| Food Chemicals Codex Listed:  | No |  
| Boiling Point: |  180.00 °C. @    1.00 mm Hg
 |  
| Boiling Point: |  100.00 °C. @    0.10 mm Hg
 |  
| Vapor Pressure: | 0.000119 mmHg @  25.00 °C. (est) |  
| Flash Point: |  316.00 °F. TCC (  157.78 °C. )
 |  
| logP (o/w): |   4.790 (est) |  
| Soluble in: |  
|   | alcohol |  |   | water, 0.5734 mg/L @ 25 °C (est) |  
| Insoluble in: |  
|   | water |  
 
  
Organoleptic Properties: 
  
Cosmetic Information: 
  
Suppliers: 
  
Safety Information: 
| European information :  |  
| Most important hazard(s):  |  | Xi - Irritant |  
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
  |  
|   |  
| Hazards identification |  
|   |  
|  Classification of the substance or mixture |  
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  
| None found. |  
|  GHS Label elements, including precautionary statements |  
|   |  
| Pictogram |  |  
|   |  
                                                                     
| Hazard statement(s) |  
| None found. |  
| Precautionary statement(s) |  
| None found. |  
| Oral/Parenteral Toxicity:  |  
| 
Not determined
 |  
| Dermal Toxicity:  |  
| 
Not determined
 |  
| Inhalation Toxicity:  |  
| 
Not determined
 |  
 
  
Safety in Use Information: 
| Category:  |  | flavor and fragrance agents |  
| RIFM Fragrance Material Safety Assessment: Search |  
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |  
| Recommendation for alpha-sinensal usage levels up to:  |  |   |     5.0000 % in the fragrance concentrate.
 |  
|   |  
| Recommendation for alpha-sinensal flavor usage levels up to:  |  
|   |    40.0000 ppm in the finished product.
 |  
 
  
Safety References: 
European Food Safety Authority (EFSA) reference(s):
 
  |  
Flavouring Group Evaluation 201: 2-Alkylated aliphatic acyclic alpha,beta-unsaturated aldehydes and precursors with or without additional double bonds from chemical subgroup 1.1.2 of FGE.19[1] View page or View pdf
 
  |  
Scientific Opinion on Flavouring Group Evaluation 201 Revision 1 (FGE.201Rev1): 2-Alkylated, aliphatic, acyclic alpha,beta-unsaturated aldehydes and precursors, with or without additional double-bonds, from chemical subgroup 1.1.2 of FGE.19. View page or View pdf
 
  |  
Scientific Opinion on Flavouring Group Evaluation 201 Revision 2 (FGE.201Rev2): 2-alkylated, aliphatic, acyclic alpha,beta-unsaturated aldehydes and precursors, with or without additional double-bonds, from chemical subgroup 1.1.2 of FGE.19 View page or View pdf
 
  |  
| EPI System: View |  
| AIDS Citations:Search |  
| Cancer Citations:Search |  
| Toxicology Citations:Search |  
| EPA Substance Registry Services (TSCA):17909-77-2 |  
| EPA ACToR:Toxicology Data |  
| EPA Substance Registry Services (SRS):Registry |  
| Laboratory Chemical Safety Summary :5281534 |  
| National Institute of Allergy and Infectious Diseases:Data |  
| WGK Germany:2 |  
| (2E,6E,9E)-2,6,10-trimethyldodeca-2,6,9,11-tetraenal |  
| Chemidplus:0017909772 |  
 
  
References: 
  
Other Information: 
  
Potential Blenders and core components  note 
  
Potential Uses: 
  
Occurrence (nature, food, other): note 
  
Synonyms: 
| 2,6- | dimethyl-10-methylene-2,6,11-dodecatriene |  | 2,6,9,11- | dodecatetraenal, 2,6,10-trimethyl-, (2E,6E,9E)- |  | 2,6,9,11- | dodecatetraenal, 2,6,10-trimethyl-, (E,E,E)- |  | a- | sinensal |  | alpha- | sinensal |  | alpha- | sinensal 21/22% ex tangerine (natural) |  |   | sinensal ex orange 20/10a |  | alpha- | sinensal natural |  | (E,E,E)-2,6,10- | trimethyl dodeca-2,6,9,11-tetraen-1-al |  | all trans- | trimethyl dodecatetraenal |  | (E,E,E)-2,6,10- | trimethyldodeca-2,6,9,11-tetraen-1-al |  | (2E,6E,9E)-2,6,10- | trimethyldodeca-2,6,9,11-tetraenal |  
 
  
Articles:
| US Patents:3,963,783 - 4-Methyl-8-vinyl-4,7- and -4,8-nonadienals |  
| PubMed:Rapid collection and identification of a novel component from Clausena lansium Skeels leaves by means of three-dimensional preparative gas chromatography and nuclear magnetic resonance/infrared/mass spectrometric analysis. |  
| US Patents:3,974,225 - Process for the preparation of unsaturated aldehydes |  
| PubMed:California Lomatiums, Part X. Comparison of composition of the hydrodistilled oils from two subspecies of Lomatium mohavense. |  
| US Patents:3,979,425 - Process for the preparation of unsaturated aldehydes |  
| PubMed:VOLATILES FROM ORANGES. 3. THE STRUCTURE OF SINENSAL. |  
| PubMed:Citrus fruit flavor and aroma biosynthesis: isolation, functional characterization, and developmental regulation of Cstps1, a key gene in the production of the sesquiterpene aroma compound valencene. |  
| PubMed:Identification of sulfur volatiles in canned orange juices lacking orange flavor. |  
| PubMed:Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger. |  
| PubMed:Repellent effect of santalol from sandalwood oil against Tetranychus urticae (Acari: Tetranychidae). |  
| PubMed:Acaricidal and oviposition deterring effects of santalol identified in sandalwood oil against two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae). |  
| PubMed:Chemical composition of the essential oils of Clausena lansium from Hainan Island, China. |  
| PubMed:Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. |  
| PubMed:Volatile constituents of redblush grapefruit (Citrus paradisi) and pummelo (Citrus grandis) peel essential oils from Kenya. |  
 
  
 |