EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

2-ethoxy-3-ethyl pyrazine
3-ethyl-2-ethoxypyrazine

Supplier Sponsors

Name:2-ethoxy-3-ethylpyrazine
CAS Number: 35243-43-7Picture of molecule3D/inchi
FDA UNII:147QYV8K8V
Nikkaji Web:J635.289H
MDL:MFCD00038026
XlogP3:2.20 (est)
Molecular Weight:152.19684000
Formula:C8 H12 N2 O
NMR Predictor:Predict (works with chrome or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:2131 2-ethoxy-3-ethylpyrazine
FEMA Number:4633 3-ethyl-2-ethoxypyrazine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):35243-43-7 ; 2-ETHOXY-3-ETHYLPYRAZINE
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.98100 to 0.98300 @ 20.00 °C.
Pounds per Gallon - (est).: 8.172 to 8.189
Refractive Index:1.49200 to 1.49500 @ 20.00 °C.
Boiling Point: 195.00 to 197.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.558000 mmHg @ 25.00 °C. (est)
Flash Point: 157.00 °F. TCC ( 69.44 °C. )
logP (o/w): 2.275 (est)
Soluble in:
 alcohol
 water, 604.6 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: potato
Odor Strength:high ,
recommend smelling in a 0.10 % solution or less
potato raw potato
Odor Description:at 0.10 % in propylene glycol. raw potato
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Axsyn
For experimental / research use only.
Pyrazine,2-ethoxy-3-ethyl-
BOC Sciences
For experimental / research use only.
2-Ethoxy-3-ethylpyrazine
M&U International
2-ETHOXY-3(5/6)-ETHYL PYRAZINE
Parchem
2-ethoxy-3-ethyl pyrazine
Sigma-Aldrich
2-Ethoxy-3-ethylpyrazine, 97%
Certified Food Grade Products
Synerzine
2-Ethoxy-3-Ethylpyrazine
TCI AMERICA
For experimental / research use only.
2-Ethoxy-3-ethylpyrazine >98.0%(GC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for 2-ethoxy-3-ethyl pyrazine usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: 0.020000.10000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 0.010000.10000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: 0.010000.10000
meat products: 0.010000.10000
milk products: --
nut products: --
other grains: 0.010000.10000
poultry: 0.010000.07000
processed fruits: --
processed vegetables: 0.010000.10000
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 0.010000.10000
soft candy: --
soups: 0.010000.10000
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :520722
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-ethoxy-3-ethylpyrazine
Chemidplus:0035243437
 
References:
 2-ethoxy-3-ethylpyrazine
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):520722
Pubchem (sid):10519777
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.99.8290
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
aldehydic
nonanal (aldehyde C-9)
FL/FR
balsamic
(E)-
benzyl tiglate
FL/FR
chocolate
2,5-
dimethyl pyrazine
FL/FR
coffee
coffee difuran
FL/FR
creamy
butyl lactate
FL/FR
earthy
dibenzyl ether
FL/FR
2-
ethyl-3-methoxypyrazine
FL/FR
1-
nonen-3-ol
FL/FR
nutty pyrazine
FL/FR
3-
octanol
FL/FR
2-
octanone
FL/FR
3-
octen-2-one
FL/FR
1-
octen-3-ol
FL/FR
1-
octen-3-one
FL/FR
fatty
(E)-2-
decenal
FL/FR
2-
nonenal
FL/FR
(Z)-
oleic acid
FL/FR
fermented
butyl laevo-lactate
FL/FR
floral
3-
decanol
FL/FR
nonyl octanoate
FL/FR
octyl acetate
FL/FR
2-
phenyl propionaldehyde dimethyl acetal
FL/FR
fruity
hexyl (E)-tiglate
FL/FR
octyl propionate
FL/FR
fungal
1-
decen-3-ol
FL/FR
methyl 2-furoate
FL/FR
green
2-sec-
butyl-3-methoxypyrazine
FL/FR
(Z)-2-
hexen-1-ol
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
(Z)-
leaf acetal
FL/FR
melon acetal
FL/FR
methyl heptine carbonate
FL/FR
(Z)-5-
octen-1-ol
FL/FR
phenyl acetaldehyde dimethyl acetal
FL/FR
herbal
3-
octanone
FL/FR
honey
phenethyl furoate
FL/FR
mushroom
3-
octen-2-ol
FL/FR
(R)-1-
octen-3-ol
FL/FR
1-
octen-3-yl butyrate
FL/FR
musty
hazelnut pyrazine
FL/FR
nutty
2-
acetyl-3-ethyl pyrazine
FL/FR
3,6-
cocoa pyrazine
FL/FR
3,5-
cocoa pyrazine
FL/FR
2-
ethyl pyrazine
FL/FR
5-
methyl quinoxaline
FL/FR
2,3,5-
trimethyl pyrazine
FL/FR
popcorn
2-
acetyl pyrazine
FL/FR
sulfurous
2-
methyl 5-(methyl thio) furan
FL/FR
tonka
6-
amyl-alpha-pyrone
FL/FR
vegetable
1-
furfuryl pyrrole
FL/FR
mesityl oxide
FL/FR
methional
FL/FR
waxy
ethyl octanoate
FL/FR
methyl laurate
FL/FR
(Z)-3-
nonen-1-ol
FL/FR
octanol
FL/FR
woody
sclareolide
FL/FR
yeasty
2-
octen-4-one
FL/FR
For Flavor
No flavor group found for these
3-
decanol
FL/FR
3-
ethyl thiopropanol
FL
2-
ethyl-3-methoxypyrazine
FL/FR
furfural diethyl acetal
FL
green pea pyrazine
FL
methionyl acetate
FL
2-
methoxy-3-propyl pyrazine
FL
methyl 2-(methyl thio) acetate
FL
S-
methyl benzothioate
FL
4-(
methyl thio) butanol
FL
tris(
methyl thio) methane
FL
1-
nonen-3-one
FL
nonyl octanoate
FL/FR
2-
pentyl-1-buten-3-one
FL
phenethyl furoate
FL/FR
lenthionine
FL
aldehydic
aldehydic
nonanal (aldehyde C-9)
FL/FR
alliaceous
1,3-
butane dithiol
FL
3-
mercapto-2-pentanone
FL
2-
methyl thioacetaldehyde
FL
truffle sulfide
FL
balsamic
(E)-
benzyl tiglate
FL/FR
buttery
butyl laevo-lactate
FL/FR
caramellic
methyl 2-furoate
FL/FR
coffee
coffee difuran
FL/FR
creamy
6-
amyl-alpha-pyrone
FL/FR
3-
octen-2-one
FL/FR
dairy
butyl lactate
FL/FR
2-
octanone
FL/FR
earthy
1-
decen-3-ol
FL/FR
difurfuryl sulfide
FL
mushroom extenders
FL
mushroom oil
FL
1-
nonen-3-ol
FL/FR
1,8-
octane dithiol
FL
1-
octen-3-one
FL/FR
2-
thienyl disulfide
FL
estery
octyl propionate
FL/FR
fatty
(E,E)-2,4-
decadienal
FL
dimethyl sulfoxide
FL
2-
nonenal
FL/FR
(Z)-
oleic acid
FL/FR
fermented
methyl thio isovalerate
FL
fruity
dibenzyl ether
FL/FR
2-
phenyl propionaldehyde dimethyl acetal
FL/FR
green
dihydroxyacetophenone (mixed isomers)
FL
(Z)-2-
hexen-1-ol
FL/FR
(Z)-3-
hexen-1-yl tiglate
FL/FR
hexyl (E)-tiglate
FL/FR
(Z)-
leaf acetal
FL/FR
melon acetal
FL/FR
methyl heptine carbonate
FL/FR
(Z)-5-
octen-1-ol
FL/FR
phenyl acetaldehyde dimethyl acetal
FL/FR
propylene glycol acetone ketal
FL
milky
dextro,laevo-3-(
methyl thio) butanone
FL
mushroom
3-
octanone
FL/FR
3-
octen-2-ol
FL/FR
(R)-1-
octen-3-ol
FL/FR
1-
octen-3-ol
FL/FR
1-
octen-3-yl butyrate
FL/FR
musty
2,5-
dimethyl pyrazine
FL/FR
hazelnut pyrazine
FL/FR
2-
methyl 5-(methyl thio) furan
FL/FR
3-
octanol
FL/FR
propionaldehyde
FL
2,3,5-
trimethyl pyrazine
FL/FR
nutty
2-
acetyl-3-ethyl pyrazine
FL/FR
3,6-
cocoa pyrazine
FL/FR
3,5-
cocoa pyrazine
FL/FR
2-
ethyl pyrazine
FL/FR
2-
ethyl-6-methyl pyrazine
FL
5-
methyl quinoxaline
FL/FR
nutty pyrazine
FL/FR
onion
methyl propyl disulfide
FL
phenolic
propyl 2-furoate
FL
potato
mesityl oxide
FL/FR
potato enhancers
FL
roasted
2-
acetyl pyrazine
FL/FR
seafood
1,4-
dithiane
FL
sulfurous
1-(
methyl thio)-2-butanone
FL
2-
naphthyl mercaptan
FL
potato butanone
FL
2,4,6-
trithiaheptane 10% in triacetin
FL
tomato
methional
FL/FR
vegetable
2-sec-
butyl-3-methoxypyrazine
FL/FR
1-
furfuryl pyrrole
FL/FR
2-
octen-4-one
FL/FR
potato butyraldehyde
FL
waxy
(E)-2-
decenal
FL/FR
ethyl octanoate
FL/FR
methyl laurate
FL/FR
(Z)-3-
nonen-1-ol
FL/FR
octanol
FL/FR
octyl 2-furoate
FL
octyl acetate
FL/FR
winey
5-
ethyl-2-methyl pyridine
FL
woody
sclareolide
FL/FR
 
Potential Uses:
FLpotato
 
Occurrence (nature, food, other):note
 hickory wood
Search PMC Picture
 potato cooked potato
Search Trop Picture
 
Synonyms:
2-ethoxy-3-ethylpyrazine
3-ethyl-2-ethoxypyrazine
 pyrazine, 2-ethoxy-3-ethyl-
 pyrazine,2-ethoxy-3-ethyl-
 

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