lavender oil greece
essential oil distilled from the flowering herbs of the lavender, lavandula angustifolia, labiatae greece
 
Notes:
Lavender Oil French is a colorless or pale yellow liquid of sweet, floral, herbaceous, fresh odor with a balsamic, woody undertone. silexan used as an anti-anxiety agent. tsca definition 2008: extractives and their physically modified derivatives. lavandula officinalis, labiatae.
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Name: lavandula angustifolia l. herb oil
CAS Number: 8000-28-0 
MDL: MFCD00147392
Also Contains: lavandula angustifolia herb extract
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2622  lavender oil greece
FDA Mainterm: LAVENDER, OIL (LAVANDULA OFFICINALIS CHAIX)
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.87700 to 0.89200 @  25.00 °C.
Pounds per Gallon - (est).: 7.298 to  7.422
Refractive Index: 1.45700 to 1.46400 @  20.00 °C.
Boiling Point: 204.00 °C. @ 760.00 mm Hg
Flash Point: 182.00 °F. TCC ( 83.33 °C. )
Soluble in:
 alcohol
 water, 20.12 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
Odor Type: floral
Odor Strength: medium
 lavender  floral  herbal  woody  
Odor Description:
at 100.00 %. 
lavender floral herbal woody
 lavender  
Taste Description:
lavender
Substantivity: 12 Hour(s)
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  4250 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 449, 1976.

intraperitoneal-rat LD50  540 mg/kg
Izvestiya na Instituta po Fiziologiya, Bulgarska Akademiya na Naukite. Vol. 15, Pg. 149, 1973.

intraperitoneal-mouse LD50  640 mg/kg
Izvestiya na Instituta po Fiziologiya, Bulgarska Akademiya na Naukite. Vol. 15, Pg. 149, 1973.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 451, 1976.

skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 449, 1976.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA fragrance material specification:
 Linalool and natural products known to be rich in linalool, such as bois de rose, coriander or ho wood oil, should only be used when the level of peroxides is kept to the lowest practical level. It is recommended to add antioxidants at the time of production of the raw material. The addition of 0.1% BHT or alpha-tocopherol for example has shown great efficiency. The maximum peroxide level for products in use should be 20 mmol/l.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
coumarin Max. Found: <0.10 % and Reason: Sensitization
geraniol Max. Found: <1.00 % and Reason: Sensitization
7-methoxycoumarin Max. Found: <0.02 % and Reason: Sentitization / Photo Sensitization
1-octen-3-yl acetate Max. Found: <1.00 % and Reason: Sensitization
IFRA: View Standard
Recommendation for lavender oil greece usage levels up to:
  8.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -8.30000
beverages(nonalcoholic): -2.90000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -220.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -7.80000
fruit ices: -7.80000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -5.50000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 8000-28-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 lavandula angustifolia l. herb oil
Chemidplus: 0008000280
RTECS: OF6110000 for cas# 8000-28-0
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References:
 lavandula angustifolia l. herb oil
Canada Domestic Sub. List: 8000-28-0
Pubchem (sid): 135362275
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.23.0000
Household Products: Search
MedlinePlusSupp: View
 Typical G.C.
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 lavender
Search Trop  Picture
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Synonyms:
 essential oil distilled from the flowering herbs of the lavender, lavandula angustifolia, labiatae greece
 lavandula angustifolia herb oil greece
 lavandula officinalis herb oil greece
 lavandula spica herb oil greece
 lavandula vera herb oil greece
 lavender oil greece
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Articles:
PubMed: Rhamnolipids as emulsifying agents for essential oil formulations: Antimicrobial effect against Candidaalbicans and methicillin-resistant Staphylococcus aureus.
PubMed: Oviposition deterrent and ovicidal activities of seven herbal essential oils against female adults of housefly, Musca domestica L.
PubMed: Antibacterial activity against Clostridium genus and antiradical activity of the essential oils from different origin.
PubMed: Membrane disruption and anti-quorum sensing effects of synergistic interaction between Lavandula angustifolia (lavender oil) in combination with antibiotic against plasmid-conferred multi-drug-resistant Escherichia coli.
PubMed: Insecticidal activity of plant essential oils against the vine mealybug, Planococcus ficus.
PubMed: Presence of monoterpene synthase in four Labiatae species and Solid-Phase Microextraction- Gas chromatography-Mass Spectroscopy analysis of their aroma profiles.
PubMed: Effect of lavender inhalation on the symptoms of primary dysmenorrhea and the amount of menstrual bleeding: A randomized clinical trial.
PubMed: Comparative studies of cytotoxic and apoptotic properties of different extracts and the essential oil of Lavandula angustifolia on malignant and normal cells.
PubMed: Effect of lavender oil (Lavandula angustifolia) on cerebral edema and its possible mechanisms in an experimental model of stroke.
PubMed: Biochemical composition and antioxidant properties of Lavandula angustifolia Miller essential oil are shielded by propolis against UV radiations.
PubMed: A randomized, controlled cross-over trial of dermally-applied lavender (Lavandula angustifolia) oil as a treatment of agitated behaviour in dementia.
PubMed: Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
PubMed: A Comparison Study of Growth Factor Expression following Treatment with Transcutaneous Electrical Nerve Stimulation, Saline Solution, Povidone-Iodine, and Lavender Oil in Wounds Healing.
PubMed: Increased seizure latency and decreased severity of pentylenetetrazol-induced seizures in mice after essential oil administration.
PubMed: The In Vitro Antimicrobial Activity of Lavandula angustifolia Essential Oil in Combination with Other Aroma-Therapeutic Oils.
PubMed: Does lavender aromatherapy alleviate premenstrual emotional symptoms?: a randomized crossover trial.
PubMed: Anosmia does not impair the anxiolytic-like effect of lavender essential oil inhalation in mice.
PubMed: Distillation time effect on lavender essential oil yield and composition.
PubMed: Anxiolytic-like effect of lavender essential oil inhalation in mice: participation of serotonergic but not GABAA/benzodiazepine neurotransmission.
PubMed: Control of the chewing louse Bovicola (Werneckiella) ocellatus in donkeys, using essential oils.
PubMed: Characterization of anxiolytic and neuropharmacological activities of Silexan.
PubMed: Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination.
PubMed: Neuroprotective effects of inhaled lavender oil on scopolamine-induced dementia via anti-oxidative activities in rats.
PubMed: Silexan, an essential oil from flowers of Lavandula angustifolia, is not recognized as benzodiazepine-like in rats trained to discriminate a diazepam cue.
PubMed: Neuroprotective activity of lavender oil on transient focal cerebral ischemia in mice.
PubMed: The effects of clinical aromatherapy for anxiety and depression in the high risk postpartum woman - a pilot study.
PubMed: Effects of lavender oil inhalation on improving scopolamine-induced spatial memory impairment in laboratory rats.
PubMed: Investigation of the chemical composition-antibacterial activity relationship of essential oils by chemometric methods.
PubMed: [Sensitivity assessment of thyme and lavender essential oils against clinical strains of Escherichia coli for their resistance].
PubMed: Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus.
PubMed: Cloning and functional characterization of β-phellandrene synthase from Lavandula angustifolia.
PubMed: [Effects of aromatherapy on changes in the autonomic nervous system, aortic pulse wave velocity and aortic augmentation index in patients with essential hypertension].
PubMed: Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model.
PubMed: An attempt of postharvest orange fruit rot control using essential oils from Mediterranean plants.
PubMed: Physical properties of gum karaya-starch-essential oil patches.
PubMed: Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae).
PubMed: Biodegradable gelatin-chitosan films incorporated with essential oils as antimicrobial agents for fish preservation.
PubMed: The study protocol of a blinded randomised-controlled cross-over trial of lavender oil as a treatment of behavioural symptoms in dementia.
PubMed: Antidepressant-like effect of Salvia sclarea is explained by modulation of dopamine activities in rats.
PubMed: Lavandula angustifolia essential oil as a novel and promising natural candidate for tick (Rhipicephalus (Boophilus) annulatus) control.
PubMed: Antibacterial activity of essential oils from palmarosa, evening primrose, lavender and tuberose.
PubMed: A genomics resource for investigating regulation of essential oil production in Lavandula angustifolia.
PubMed: Effects of ultraviolet radiation on the kinetics of in vitro percutaneous absorption of lavender oil.
PubMed: Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.
PubMed: The antimicrobial activity of high-necrodane and other lavender oils on methicillin-sensitive and -resistant Staphylococcus aureus (MSSA and MRSA).
PubMed: Lavandula angustifolia Miller: English lavender.
PubMed: Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels.
PubMed: Improved microwave steam distillation apparatus for isolation of essential oils. Comparison with conventional steam distillation.
PubMed: Comparative chemometric analyses of geographic origins and compositions of lavandin var. Grosso essential oils by mid infrared spectroscopy and gas chromatography.
PubMed: Analysis of the volatile compounds of flowers and essential oils from Lavandula angustifolia cultivated in Northeastern Italy by headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry.
PubMed: Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia).
PubMed: Repellence of the red bud borer Resseliella oculiperda from grafted apple trees by impregnation of rubber budding strips with essential oils.
PubMed: Anxiolytic effects of Lavandula angustifolia odour on the Mongolian gerbil elevated plus maze.
PubMed: Repellency of oils of lemon eucalyptus, geranium, and lavender and the mosquito repellent MyggA natural to Ixodes ricinus (Acari: Ixodidae) in the laboratory and field.
PubMed: Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata.
PubMed: The in vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from Portugal.
PubMed: Hydrodistillation-headspace solvent microextraction, a new method for analysis of the essential oil components of Lavandula angustifolia Mill.
PubMed: Antifungal activity of Lavandula angustifolia essential oil against Candida albicans yeast and mycelial form.
PubMed: The antimutagenic activity of Lavandula angustifolia (lavender) essential oil in the bacterial reverse mutation assay.
PubMed: Antifungal effect of various essential oils against Candida albicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris.
PubMed: Effect of essential oil concentration on the pH of nutrient and Iso-sensitest broth.
PubMed: Lavender (Lavandula angustifolia Miller).
PubMed: Cytotoxicity of lavender oil and its major components to human skin cells.
PubMed: Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill.
PubMed: Anti-Aspergillus activities of plant essential oils and their combination effects with ketoconazole or amphotericin B.
PubMed: Activity of essential oils from Mediterranean Lamiaceae species against food spoilage yeasts.
PubMed: On-site field sampling and analysis of fragrance from living lavender (Lavandula angustifolia L.) flowers by solid-phase microextraction coupled to gas chromatography and ion-trap mass spectrometry.
PubMed: GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum.
PubMed: Local anaesthetic activity of the essential oil of Lavandula angustifolia.
PubMed: Studies on the mode of action of the essential oil of lavender (Lavandula angustifolia P. Miller).
PubMed: Acaricidal agents of natural origin against Psoroptes cuniculi.
PubMed: Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation.
PubMed: [Neurodepressive effects of the essential oil of Lavandula angustifolia Mill].
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