white sassafras oil
sassafras albidum oil
 
Notes:
DO NOT use at all because of toxic effects. tsca definition 2008: extractives and their physically modified derivatives. sassafras albidum, lauraceae.
  • Berjé
    • Berje Inc.
      The solution is clear
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
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      Happening at Berje
      Product(s):
      Sassafras Oil
       
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co.
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      HL0480 Sassafras oil (safrol 80%)
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
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      Product(s):
      SASSAFRAS OIL
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      19-11005 SASAFRAS OIL, NATURAL, Kosher
       
  • Treatt
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
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      Product(s):
      Sassafras Oil
       
Synonyms   Articles   Notes   Search
Name: sassafras albidum (nuttall) nees oil
CAS Number: 8006-80-2 
FDA UNII: 78ZX2PFG2Z
MDL: MFCD00148252
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: yellowish brown clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 1.07900 to 1.09800 @  25.00 °C.
Pounds per Gallon - (est).: 8.978 to  9.136
Refractive Index: 1.53300 to 1.53700 @  20.00 °C.
Boiling Point: 236.00 °C. @ 760.00 mm Hg
Flash Point: 225.00 °F. TCC ( 107.22 °C. )
Soluble in:
 water, 75.98 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor Type: spicy
 
Odor Strength: medium ,
recommend smelling in a 1.00 % solution or less
 
Substantivity: 144 Hour(s)
 
 sweet  spicy  fresh  camphoreous  woody  floral  root beer  sarsaparilla  
Odor Description:
at 1.00 % in dipropylene glycol. 
sweet spicy fresh camphor woody floral rootbeer
Luebke, William tgsc, (1983)
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Aceto
Sassafras Oil
Berjé
Sassafras Oil
Happening at Berje
Blue Pacific Flavors
Sassafras Oil
BOC Sciences
For experimental / research use only.
Sassafras Oil imitation
George Uhe Company
Sassafras Oil
Available from Various Origins
Jiangyin Healthway
Sassafras oil (safrol 80%)
New functional food ingredients
Kanta Enterprises
Sassafras Oil
Lluch Essence
SASSAFRAS OIL
Noble Molecular Research
For experimental / research use only.
Sassafas Oil
Penta International
SASAFRAS OIL, NATURAL, Kosher
Reincke & Fichtner
Sassafras Oil organic + NOP
Reincke & Fichtner
Sassafras Oil
Treatt
Sassafras Oil
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Safety Information:
European information :
Most important hazard(s):
T - Toxic.
R 22 - Harmful if swallowed.
R 45 - May cause cancer.
R 68 - Possible risk of irreversible effects.
S 01/02 - Keep locked up and out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 23 - Do not breath vapour.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
S 53 - Avoid exposure - obtain special instructions before use.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  1900 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

oral-man LDLo  83 mg/kg
SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA fragrance material specification:
 Safrole as such should not be used as a fragrance ingredient; essential oils containing safrole should not be used at a level such that the total concentration of safrole exceeds 0.01% in consumer products. Examples of essential oils with a high safrole content are Sassafras oil (Sassafras officinale Nees& Eberm.), Ocotea Cymbarum oil (Ocotea pretiosa Metz) and certain qualities of Camphor oils. The total concentration of safrole, isosafrole and dihydrosafrole should not exceed 0.01% in consumer products.
IFRA: View Standard
Recommendation for white sassafras oil usage levels up to:
  4.0000 % in the fragrance concentrate.
 
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Safety References:
EPI System: View
Daily Med: search
EPA Substance Registry Services (TSCA): 8006-80-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 sassafras albidum (nuttall) nees oil
Chemidplus: 0008006802
RTECS: RJ3400000 for cas# 8006-80-2
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References:
 sassafras albidum (nuttall) nees oil
Canada Domestic Sub. List: 8006-80-2
Pubchem (sid): 135355615
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Other Information:
Export Tariff Code: 3301.29.6000
Wikipedia: View
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: SASSAFRAS OIL
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Potential Blenders and core components note
 
For Odor
aldehydic
2,6-dimethyl-2,18-nonadecadien-8-one 
anisic
 dihydroanetholFL/FR
 estragoleFL/FR
bitter fennel seed oil spainFR
 ocotea cymbarum oil 
 sassafras acetateFL/FR
balsamic
dextro,laevo-borneolFL/FR
laevo-borneolFL/FR
isobornyl methyl etherFL/FR
 guaiacyl phenyl acetateFL/FR
berry
sec-butyl ethyl etherFL/FR
camphoreous
 bornyl ethyl ether 
2,6-dimethyl-3-oxatricyclo(4.2.1.0*2,4*)nonaneFR
chocolate
1,3,3,4,5,6-hexamethyl(2.2.2)bicyclooct-5-en-2-ol 
citrus
 citrus woody floral fragranceFR
 myrcenyl acetateFL/FR
earthy
(-)-alpha-fencholFL/FR
(Z)-linalool oxide (furanoid)FL/FR
floral
 amyl cyclopentenoneCS
 bois de rose oil peruFL/FR
 cassie absoluteFL/FR
delta-damasconeFL/FR
 dihydro-alpha-iononeFL/FR
2',4'-dimethyl acetophenoneFL/FR
2,4-dimethyl cyclohexyl methyl acetateFR
4-dimethyl iononeFR
 elder flower wood specialtyFR
 epoxylinalyl acetate 
 ho leaf oilFR
(E)-beta-iononeFL/FR
alpha-iononeFL/FR
alpha-ionyl acetateFR
 lavandula angustifolia flower oilFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
laevo-linaloolFL/FR
 linalool oxideFL/FR
 melaleuca ericifolia leaf oilFR
alpha-isomethyl ionone (60% min.)FL/FR
alpha-isomethyl ionone (70% min.)FL/FR
alpha-isomethyl ionone (80% min.)FL/FR
2-methyl naphthaleneFL/FR
4-methyl-2-(2-methyl propyl)-1,3-oxathiane 
 mimosa concrete franceFL/FR
 mimosa tenuiflora leaf extractFL/FR
bitter orangeflower concreteFR
 orris rhizome absolute replacerFR
 petitgrain cedrat oilFL/FR
 petitgrain oil terpenesFR
 phenethyl hexanoateFL/FR
 rose concrete (rosa centifolia)FR
 styralyl formateFL/FR
 vetiver pentanoneFR
fruity
3-allyl oxy-1,4-dimethyl bicyclo(3.2.1)octaneFR
1,4-diisopropyl-6,8-dioxabicyclo(3.2.1)octaneFR
2-ethyl butyl 2-butenoate 
 linalool oxide acetatesFL/FR
 octyl propionateFL/FR
1,3,3,5-tetramethyl-7 and 8-acetyl bicyclo(2.2.2)oct-5-ene 
 tropical iononeFL/FR
green
isogreen methanoindeneFR
(E)-2-hexen-1-yl salicylateFR
para-methyl hydratropaldehydeFL/FR
herbal
1-allyl-2,2,7,7-tetramethyl cycloheptanolFR
 calendula officinalis flower oil CO2 extractFR
 dimethyl cyclormol (IFF)FR
 freesia heptanolFL/FR
 geranic oxideFL/FR
 herbal dioxaneFR
 immortelle flower oilFL/FR
 laurel bark oil 
 laurel stem oil 
 marigold pot flower oilFL/FR
 methyl cyclogeranateFR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 rosemary absoluteFL/FR
 rosemary oilFL/FR
 rosemary oil africaFL/FR
 rosemary oil moroccoFL/FR
 rosemary oil spainFL/FR
 rosemary oil tunisiaFL/FR
 rosmarinus officinalis extractFL/FR
 thymolFL/FR
 peppermint cyclohexanoneFL/FR
minty
bitter fennel seed oil CO2 extractFR
 pennyroyal oilFL/FR
5- and 6-isopropyl-1,3,3-trimethyl bicyclo(2.2.2)-5,7-octadien-2-one 
mossy
 moss specialtyFR
musk
 amyris specialtyFR
 ethylene brassylateFL/FR
powdery
(E)-alpha-methyl ionone (44-50%)FL/FR
rummy
 rum extractFL/FR
spicy
2,4-dimethyl-alpha-isopropyl-3-cyclohexene-1-methanol 
 elettaria cardamomum seed oilFL/FR
 elettaria cardamomum seed oil guatemalaFL/FR
isoeugenolFL/FR
 galangal root oilFL/FR
 laurus nobilis fruit oilFL/FR
 laurus nobilis leaf oilFL/FR
 marjoram absolute spain 
 safroleCS
isosafrole 
 sassafras albidum bark tincture (safrol free)FL/FR
 sassafras albidum leaf (safrole-free) 
 sassafras fragranceFR
 spicy carbonateFR
 zvoulimba leaf oilFR
terpenic
alpha-terpineolFL/FR
thujonic
 cedarleaf oil terpenelessFR
woody
 anthocephalus cadamba oilFR
 bois de rose leaf oil brazilFL/FR
 bornyl valerateFL/FR
2-tert-butyl cyclohexanoneFR
 cabreuva wood oilFR
 chloranthus spicatus absoluteFR
 convolvulus scoparius wood oil 
2-decalinyl acetateFR
 dihydro-beta-ionolFL/FR
3',4'-dimethoxyacetophenone 
10-epi-gamma-eudesmol 
 hedychium spicatum root oilFR
1,2,3,3,4,5,6-heptamethyl bicyclo(2.2.2)oct-5-en-2-ol 
 hinoki root oilFR
 homalomena rubescens root oilFR
 juniper berry oil terpenesFR
3-methyl pentyl angelateFR
 sandal octanolFR
 santalyl acetateFL/FR
1,3,3,5-tetramethyl-7 and 8-cyanobicyclo(2.2.2)oct-5-ene 
 zdravetz absoluteFR
 zdravetz oilFL/FR
 zedoary bark oilFL/FR
 
For Flavor
 
No flavor group found for these
dextro,laevo-borneolFL/FR
isobornyl methyl etherFL/FR
sec-butyl ethyl etherFL/FR
alpha-campholene acetateFL
 convolvulus scoparius wood oil 
 dihydro-beta-ionolFL/FR
2',4'-dimethyl acetophenoneFL/FR
2,6-dimethyl-2,18-nonadecadien-8-one 
 epoxylinalyl acetate 
2-ethyl butyl 2-butenoate 
10-epi-gamma-eudesmol 
1,2,3,3,4,5,6-heptamethyl bicyclo(2.2.2)oct-5-en-2-ol 
1,3,3,4,5,6-hexamethyl(2.2.2)bicyclooct-5-en-2-ol 
 laurel bark oil 
 laurel stem oil 
 laurus nobilis fruit oilFL/FR
 laurus nobilis leaf oilFL/FR
(Z)-linalool oxide (furanoid)FL/FR
 linalool oxide acetatesFL/FR
 marigold pot flower oilFL/FR
 marjoram absolute spain 
(E)-alpha-methyl ionone (44-50%)FL/FR
alpha-isomethyl ionone (60% min.)FL/FR
4-methyl-2-(2-methyl propyl)-1,3-oxathiane 
 ocotea cymbarum oil 
5- and 6-isopropyl-1,3,3-trimethyl bicyclo(2.2.2)-5,7-octadien-2-one 
isosafrole 
 styralyl formateFL/FR
1,3,3,5-tetramethyl-7 and 8-acetyl bicyclo(2.2.2)oct-5-ene 
1,3,3,5-tetramethyl-7 and 8-cyanobicyclo(2.2.2)oct-5-ene 
 zdravetz oilFL/FR
berry
 dihydro-alpha-iononeFL/FR
camphoreous
laevo-borneolFL/FR
 bornyl ethyl ether 
(-)-alpha-fencholFL/FR
 geranic oxideFL/FR
 rosemary oil tunisiaFL/FR
citrus
 freesia heptanolFL/FR
laevo-linaloolFL/FR
 myrcenyl acetateFL/FR
 petitgrain cedrat oilFL/FR
alpha-terpineolFL/FR
cooling
isomentholFL
estery
 octyl propionateFL/FR
floral
 bois de rose leaf oil brazilFL/FR
 bois de rose oil peruFL/FR
alpha-iononeFL/FR
alpha-isomethyl ionone (70% min.)FL/FR
alpha-isomethyl ionone (80% min.)FL/FR
 mimosa concrete franceFL/FR
 mimosa tenuiflora leaf extractFL/FR
 tropical iononeFL/FR
green
 linalool oxideFL/FR
para-methyl hydratropaldehydeFL/FR
herbal
 dihydroanetholFL/FR
 immortelle flower oilFL/FR
 lavandula angustifolia flower oilFL/FR
 lavender oil franceFL/FR
 lavender oil greeceFL/FR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 rosemary absoluteFL/FR
 rosemary oilFL/FR
 rosemary oil africaFL/FR
 rosemary oil moroccoFL/FR
 rosemary oil spainFL/FR
 rosmarinus officinalis extractFL/FR
licorice
 estragoleFL/FR
mentholic
 peppermint cyclohexanoneFL/FR
minty
 pennyroyal oilFL/FR
musk
 ethylene brassylateFL/FR
oily
2-methyl naphthaleneFL/FR
phenolic
 guaiacyl phenyl acetateFL/FR
 thymolFL/FR
rummy
 rum extractFL/FR
spicy
 cassie absoluteFL/FR
2,4-dimethyl-alpha-isopropyl-3-cyclohexene-1-methanol 
 elettaria cardamomum seed oilFL/FR
 elettaria cardamomum seed oil guatemalaFL/FR
isoeugenolFL/FR
 galangal root oilFL/FR
 sassafras albidum bark extract (safrol free)FL
 sassafras albidum bark tincture (safrol free)FL/FR
 sassafras albidum extract (safrole-free)FL
 sassafras albidum leaf (safrole-free) 
tarragon
 sassafras acetateFL/FR
waxy
 phenethyl hexanoateFL/FR
woody
 bornyl valerateFL/FR
delta-damasconeFL/FR
3',4'-dimethoxyacetophenone 
(E)-beta-iononeFL/FR
 santalyl acetateFL/FR
 zedoary bark oilFL/FR
 
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Potential Uses:
 cinnamonFR
 windsor soap 
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Occurrence (nature, food, other): note
 sassafras
Search Trop  Picture
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Synonyms:
 laurus albida oil
 laurus sassafras oil
 sassafras albidum oil
 sassafras albidum var. molle oil
 sassafras officinalis oil
 sassafras oil chinese
 sassafras sassafras oil
 sassafras variifolium oil
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Articles:
PubMed: Forensic profiling of sassafras oils based on comprehensive two-dimensional gas chromatography.
PubMed: Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
PubMed: Effect of tree species and end seal on attractiveness and utility of cut bolts to the redbay ambrosia beetle and granulate ambrosia beetle (coleoptera: Curculionidae: Scolytinae).
PubMed: Safrole-2',3'-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice.
PubMed: Biological reactive intermediates (BRIs) formed from botanical dietary supplements.
PubMed: Pharmacological characterization of (3-thienylidene)-3,4-methylenedioxybenzoylhydrazide: a novel muscarinic agonist with antihypertensive profile.
PubMed: A study of impurities in intermediates and 3,4-methylenedioxymethamphetamine (MDMA) samples produced via reductive amination routes.
PubMed: Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole.
PubMed: The chemical composition of some Lauraceae essential oils and their antifungal activities.
PubMed: Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
PubMed: Synthesis and antiplatelet evaluation of novel aryl-sulfonamide derivatives, from natural safrole.
PubMed: Synthesis and cytotoxic activity of N-substituted thiosemicarbazones of 3-(3,4-methylenedioxy)phenylpropanal.
PubMed: Liquid chromatographic determination of safrole in sassafras-derived herbal products.
PubMed: Chemical composition of essential oil from the root bark of Sassafras albidum.
PubMed: Symptomatic sassafras oil ingestion.
PubMed: Investigation of the chemical constituents of Brazilian sassafras oil.
PubMed: An investigation of Brazilian sassafras oil; a comparison with oil of sassafras U.S.P. in regard to taste and odor preference.
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