EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

white sassafras oil
sassafras albidum oil

Sponsors

Name:sassafras albidum (nuttall) nees oil
CAS Number: 8006-80-2
FDA UNII:78ZX2PFG2Z
MDL:MFCD00148252
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:yellowish brown clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity:1.07900 to 1.09800 @ 25.00 °C.
Pounds per Gallon - (est).: 8.978 to 9.136
Refractive Index:1.53300 to 1.53700 @ 20.00 °C.
Boiling Point: 236.00 °C. @ 760.00 mm Hg
Flash Point: 225.00 °F. TCC ( 107.22 °C. )
Soluble in:
 water, 75.98 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Type: spicy
Odor Strength:medium ,
recommend smelling in a 1.00 % solution or less
Substantivity:144 hour(s) at 100.00 %
sweet spicy fresh camphoreous woody floral root beer sarsaparilla
Odor Description:at 1.00 % in dipropylene glycol. sweet spicy fresh camphor woody floral rootbeer
Luebke, William tgsc, (1983)
Odor sample from: Berje Inc.
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Aceto
Sassafras Oil
Berjé
Sassafras Oil
Happening at Berje
Blue Pacific Flavors
Sassafras Oil
BOC Sciences
For experimental / research use only.
Sassafras Oil imitation
Frutarom
SASSAFRAS SUBSTITUTE
George Uhe Company
Sassafras Oil
Available from Various Origins
Jiangyin Healthway
Sassafras oil (safrol 80%)
New functional food ingredients
Kanta Enterprises
Sassafras Oil
Lluch Essence
SASSAFRAS OIL
Noble Molecular Research
For experimental / research use only.
Sassafas Oil
Penta International
SASAFRAS OIL, NATURAL, Kosher
Reincke & Fichtner
Sassafras Oil organic + NOP
Reincke & Fichtner
Sassafras Oil
Treatt
Sassafras Oil
 
Safety Information:
European information :
Most important hazard(s):
T - Toxic.
R 22 - Harmful if swallowed.
R 45 - May cause cancer.
R 68 - Possible risk of irreversible effects.
S 01/02 - Keep locked up and out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 23 - Do not breath vapour.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
S 53 - Avoid exposure - obtain special instructions before use.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1900 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

oral-man LDLo 83 mg/kg
SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
IFRA fragrance material specification:
 Safrole as such should not be used as a fragrance ingredient; essential oils containing safrole should not be used at a level such that the total concentration of safrole exceeds 0.01% in consumer products. Examples of essential oils with a high safrole content are Sassafras oil (Sassafras officinale Nees& Eberm.), Ocotea Cymbarum oil (Ocotea pretiosa Metz) and certain qualities of Camphor oils. The total concentration of safrole, isosafrole and dihydrosafrole should not exceed 0.01% in consumer products.
IFRA: View Standard
Recommendation for white sassafras oil usage levels up to:
  4.0000 % in the fragrance concentrate.
 
 
Safety References:
EPI System: View
Daily Med:search
EPA Substance Registry Services (TSCA):8006-80-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
sassafras albidum (nuttall) nees oil
Chemidplus:0008006802
RTECS:RJ3400000 for cas# 8006-80-2
 
References:
 sassafras albidum (nuttall) nees oil
Canada Domestic Sub. List:8006-80-2
Pubchem (sid):135355615
 
Other Information:
Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:SASSAFRAS OIL
 
Potential Blenders and core components note
For Odor
anisic
dihydroanethol
FL/FR
estragole
FL/FR
bitter
fennel seed oil spain
FR
sassafras acetate
FL/FR
balsamic
laevo-
borneol
FL/FR
dextro,laevo-
borneol
FL/FR
iso
bornyl methyl ether
FL/FR
guaiacyl phenyl acetate
FL/FR
berry
sec-
butyl ethyl ether
FL/FR
camphoreous
2,6-
dimethyl-3-oxatricyclo(4.2.1.0*2,4*)nonane
FR
citrus
citrus woody floral fragrance
FR
myrcenyl acetate
FL/FR
earthy
(-)-alpha-
fenchol
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
floral
amyl cyclopentenone
CS
bois de rose oil peru
FL/FR
cassie absolute
FL/FR
delta-
damascone
FL/FR
dihydro-alpha-ionone
FL/FR
2',4'-
dimethyl acetophenone
FL/FR
2,4-
dimethyl cyclohexyl methyl acetate
FR
4-
dimethyl ionone
FR
elder flower wood specialty
FR
ho leaf oil
FR
(E)-beta-
ionone
FL/FR
alpha-
ionone
FL/FR
alpha-
ionyl acetate
FR
lavandula angustifolia flower oil
FL/FR
lavender oil france
FL/FR
lavender oil greece
FL/FR
laevo-
linalool
FL/FR
linalool oxide
FL/FR
melaleuca ericifolia leaf oil
FR
alpha-iso
methyl ionone (60% min.)
FL/FR
alpha-iso
methyl ionone (70% min.)
FL/FR
alpha-iso
methyl ionone (80% min.)
FL/FR
2-
methyl naphthalene
FL/FR
mimosa concrete france
FL/FR
mimosa tenuiflora leaf extract
FL/FR
bitter
orangeflower concrete
FR
orris rhizome absolute replacer
FR
petitgrain cedrat oil
FL/FR
petitgrain oil terpenes
FR
phenethyl hexanoate
FL/FR
rose concrete (rosa centifolia)
FR
styralyl formate
FL/FR
vetiver pentanone
FR
fruity
3-
allyl oxy-1,4-dimethyl bicyclo(3.2.1)octane
FR
1,4-
diisopropyl-6,8-dioxabicyclo(3.2.1)octane
FR
linalool oxide acetates
FL/FR
octyl propionate
FL/FR
tropical ionone
FL/FR
green
iso
green methanoindene
FR
(E)-2-
hexen-1-yl salicylate
FR
para-
methyl hydratropaldehyde
FL/FR
herbal
1-
allyl-2,2,7,7-tetramethyl cycloheptanol
FR
calendula officinalis flower oil CO2 extract
FR
dimethyl cyclormol (IFF)
FR
freesia heptanol
FL/FR
geranic oxide
FL/FR
herbal dioxane
FR
immortelle flower oil
FL/FR
marigold pot flower oil
FL/FR
methyl cyclogeranate (Firmenich)
FR
origanum oil
FL/FR
origanum oil greece
FL/FR
rosemary absolute
FL/FR
rosemary oil
FL/FR
rosemary oil africa
FL/FR
rosemary oil morocco
FL/FR
rosemary oil spain
FL/FR
rosemary oil tunisia
FL/FR
rosmarinus officinalis extract
FL/FR
thymol
FL/FR
mentholic
peppermint cyclohexanone
FL/FR
minty
bitter
fennel seed oil CO2 extract
FR
pennyroyal oil
FL/FR
mossy
moss specialty
FR
musk
amyris specialty
FR
ethylene brassylate
FL/FR
powdery
(E)-alpha-
methyl ionone (44-50%)
FL/FR
rummy
rum extract
FL/FR
spicy
elettaria cardamomum seed oil
FL/FR
elettaria cardamomum seed oil guatemala
FL/FR
iso
eugenol
FL/FR
galangal root oil
FL/FR
laurus nobilis fruit oil
FL/FR
laurus nobilis leaf oil
FL/FR
safrole
CS
sassafras albidum bark tincture (safrol free)
FL/FR
sassafras fragrance
FR
spicy carbonate
FR
zvoulimba leaf oil
FR
terpenic
alpha-
terpineol
FL/FR
thujonic
cedarleaf oil terpeneless
FR
woody
anthocephalus cadamba oil
FR
bois de rose leaf oil brazil
FL/FR
bornyl valerate
FL/FR
2-tert-
butyl cyclohexanone
FR
cabreuva wood oil
FR
chloranthus spicatus absolute
FR
2-
decalinyl acetate
FR
dihydro-beta-ionol
FL/FR
hedychium spicatum root oil
FR
hinoki root oil
FR
homalomena rubescens root oil
FR
juniper berry oil terpenes
FR
3-
methyl pentyl angelate
FR
sandal octanol
FR
santalyl acetate
FL/FR
zdravetz absolute
FR
zdravetz oil
FL/FR
zedoary bark oil
FL/FR
For Flavor
No flavor group found for these
dextro,laevo-
borneol
FL/FR
iso
bornyl methyl ether
FL/FR
sec-
butyl ethyl ether
FL/FR
alpha-
campholene acetate
FL
dihydro-beta-ionol
FL/FR
2',4'-
dimethyl acetophenone
FL/FR
laurus nobilis fruit oil
FL/FR
laurus nobilis leaf oil
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
linalool oxide acetates
FL/FR
marigold pot flower oil
FL/FR
(E)-alpha-
methyl ionone (44-50%)
FL/FR
alpha-iso
methyl ionone (60% min.)
FL/FR
styralyl formate
FL/FR
zdravetz oil
FL/FR
berry
berry
dihydro-alpha-ionone
FL/FR
camphoreous
laevo-
borneol
FL/FR
(-)-alpha-
fenchol
FL/FR
geranic oxide
FL/FR
rosemary oil tunisia
FL/FR
citrus
freesia heptanol
FL/FR
laevo-
linalool
FL/FR
myrcenyl acetate
FL/FR
petitgrain cedrat oil
FL/FR
alpha-
terpineol
FL/FR
cooling
iso
menthol
FL
estery
octyl propionate
FL/FR
floral
bois de rose leaf oil brazil
FL/FR
bois de rose oil peru
FL/FR
alpha-
ionone
FL/FR
alpha-iso
methyl ionone (70% min.)
FL/FR
alpha-iso
methyl ionone (80% min.)
FL/FR
mimosa concrete france
FL/FR
mimosa tenuiflora leaf extract
FL/FR
tropical ionone
FL/FR
green
linalool oxide
FL/FR
para-
methyl hydratropaldehyde
FL/FR
herbal
dihydroanethol
FL/FR
immortelle flower oil
FL/FR
lavandula angustifolia flower oil
FL/FR
lavender oil france
FL/FR
lavender oil greece
FL/FR
origanum oil
FL/FR
origanum oil greece
FL/FR
rosemary absolute
FL/FR
rosemary oil
FL/FR
rosemary oil africa
FL/FR
rosemary oil morocco
FL/FR
rosemary oil spain
FL/FR
rosmarinus officinalis extract
FL/FR
licorice
estragole
FL/FR
mentholic
peppermint cyclohexanone
FL/FR
minty
pennyroyal oil
FL/FR
musk
ethylene brassylate
FL/FR
oily
2-
methyl naphthalene
FL/FR
phenolic
guaiacyl phenyl acetate
FL/FR
thymol
FL/FR
rummy
rum extract
FL/FR
spicy
cassie absolute
FL/FR
elettaria cardamomum seed oil
FL/FR
elettaria cardamomum seed oil guatemala
FL/FR
iso
eugenol
FL/FR
galangal root oil
FL/FR
sassafras albidum bark extract (safrol free)
FL
sassafras albidum bark tincture (safrol free)
FL/FR
sassafras albidum extract (safrole-free)
FL
tarragon
sassafras acetate
FL/FR
waxy
phenethyl hexanoate
FL/FR
woody
bornyl valerate
FL/FR
delta-
damascone
FL/FR
(E)-beta-
ionone
FL/FR
santalyl acetate
FL/FR
zedoary bark oil
FL/FR
 
Potential Uses:
FRcinnamon
 windsor soap
 
Occurrence (nature, food, other):note
 sassafras
Search Trop Picture
 
Synonyms:
 laurus albida oil
 laurus sassafras oil
 sassafras albidum oil
 sassafras albidum var. molle oil
 sassafras officinalis oil
 sassafras oil chinese
 sassafras sassafras oil
 sassafras variifolium oil
 

Articles:

PubMed:Forensic profiling of sassafras oils based on comprehensive two-dimensional gas chromatography.
PubMed:Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
PubMed:Effect of tree species and end seal on attractiveness and utility of cut bolts to the redbay ambrosia beetle and granulate ambrosia beetle (coleoptera: Curculionidae: Scolytinae).
PubMed:Safrole-2',3'-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice.
PubMed:Biological reactive intermediates (BRIs) formed from botanical dietary supplements.
PubMed:Pharmacological characterization of (3-thienylidene)-3,4-methylenedioxybenzoylhydrazide: a novel muscarinic agonist with antihypertensive profile.
PubMed:A study of impurities in intermediates and 3,4-methylenedioxymethamphetamine (MDMA) samples produced via reductive amination routes.
PubMed:Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole.
PubMed:The chemical composition of some Lauraceae essential oils and their antifungal activities.
PubMed:Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
PubMed:Synthesis and antiplatelet evaluation of novel aryl-sulfonamide derivatives, from natural safrole.
PubMed:Synthesis and cytotoxic activity of N-substituted thiosemicarbazones of 3-(3,4-methylenedioxy)phenylpropanal.
PubMed:Liquid chromatographic determination of safrole in sassafras-derived herbal products.
PubMed:Chemical composition of essential oil from the root bark of Sassafras albidum.
PubMed:Symptomatic sassafras oil ingestion.
PubMed:Investigation of the chemical constituents of Brazilian sassafras oil.
PubMed:An investigation of Brazilian sassafras oil; a comparison with oil of sassafras U.S.P. in regard to taste and odor preference.
 
Notes:
DO NOT use at all because of toxic effects. tsca definition 2008: extractives and their physically modified derivatives. sassafras albidum, lauraceae.
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