EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

2-isopropyl phenol
2-isopropylphenol

Supplier Sponsors

CAS Number: 88-69-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:201-852-8
FDA UNII:B2899Z0Q2U
Nikkaji Web:J44.155D
Beilstein Number:1363322
MDL:MFCD00002224
CoE Number:11234
XlogP3:2.90 (est)
Molecular Weight:136.19384000
Formula:C9 H12 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:697 2-isopropylphenol
FLAVIS Number:04.044 (Old)
DG SANTE Food Flavourings:04.044 2-isopropylphenol
FEMA Number:3461 2-isopropylphenol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):88-69-7 ; 2-ISOPROPYLPHENOL
 
Physical Properties:
Appearance:colorless to pale orange clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.98900 to 0.99900 @ 25.00 °C.
Pounds per Gallon - (est).: 8.229 to 8.313
Refractive Index:1.52500 to 1.53000 @ 20.00 °C.
Melting Point: 14.00 to 16.00 °C. @ 760.00 mm Hg
Boiling Point: 212.00 to 214.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.112000 mmHg @ 25.00 °C. (est)
Flash Point: 192.00 °F. TCC ( 88.89 °C. )
logP (o/w): 2.880
Soluble in:
 alcohol
 water, 1146 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: phenolic
Odor Strength:medium ,
recommend smelling in a 0.10 % solution or less
medicinal phenolic
Odor Description:at 0.10 % in propylene glycol. medicinal creosote phenolic
solvent phenolic smoky toasted woody burnt rubbery
Odor Description:at 1.00 %. solvent like, phenolic, smoky with toasted woody and burnt rubber nuances
Mosciano, Gerard, (2009)
Flavor Type: solvent
solvent woody smoky whiskey resinous burnt rubbery
Taste Description: at 10.00 ppm. solvent like, shoe polish, woody smoky, aged scotch and whiskey like with tar and burnt rubber nuances
Mosciano, Gerard, (2009)
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Beijing Lys Chemicals
2-Isopropyl phenol
Charkit Chemical
ISOPROPYLPHENOL, 2-
EMD Millipore
For experimental / research use only.
2-isoPropylphenol
Parchem
2-isopropyl phenol
Penta International
2-ISOPROPYLPHENOL
Santa Cruz Biotechnology
For experimental / research use only.
2-isopropylphenol
Sigma-Aldrich
2-Isopropylphenol, ≥98%, FG
Odor: medicinal
Certified Food Grade Products
Synerzine
2-isoPropylphenol
TCI AMERICA
For experimental / research use only.
2-isopropylphenol >98.0%(GC)
WholeChem
2-Isopropylphenol
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
T - Toxic.
R 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
R 34 - Causes burns.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 23 - Do not breath vapour.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 28 - After contact with skin, wash immediately with plenty of water.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 100 mg/kg
BEHAVIORAL: SLEEP
Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 14.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.30 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 9
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -2.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: -3.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -3.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: -2.00000
snack foods: --
soft candy: --
soups: -3.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 22 (FGE.22): Ring-substituted phenolic substances from chemical groups 21 and 25 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 58 (FGE.58) Consideration of phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated by EFSA in FGE.22 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 22, Revision 1 (FGE.22Rev1): Ring-substituted phenolic substances from chemical groups 21 and 25
View page or View pdf

Scientific Opinion on the safety and efficacy of phenol derivatives containing ring-alkyl, ring-alkoxy and side-chains with an oxygenated functional group (chemical group 25) when used as flavourings for all species
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):88-69-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6943
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 3145
WGK Germany:3
2-propan-2-ylphenol
Chemidplus:0000088697
EPA/NOAA CAMEO:hazardous materials
RTECS:SL5900000 for cas# 88-69-7
 
References:
 2-propan-2-ylphenol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:88-69-7
Pubchem (cid):6943
Pubchem (sid):134972349
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB32029
FooDB:FDB008729
Export Tariff Code:2907.19.2000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
butyl paraben
CS
anisic
anisic
ortho-
acetanisole
FL/FR
ortho-
anisaldehyde
FL/FR
estragole
FL/FR
balsamic
amyris wood oil
FL/FR
sumatra
benzoin absolute
FL/FR
guaiacyl phenyl acetate
FL/FR
burnt
rum ether
FL/FR
camphoreous
dextro-
camphor
FL/FR
caramellic
levulinic acid
FL/FR
chocolate
vanillyl ethyl ether
FL/FR
coffee
furfuryl mercaptan
FL/FR
coumarinic
phthalide
FL/FR
creamy
para-
vanillyl alcohol
FL/FR
floral
benzyl alcohol
FL/FR
champaca absolute
FR
para-
cresyl acetate
FL/FR
dimethyl anthranilate
FL/FR
ortho-
methyl acetophenone
FL/FR
fruity
ethyl 3-hydroxyhexanoate
FL/FR
para-
tolualdehyde
FL/FR
meta-
tolualdehyde
FL/FR
green
3,7-
dimethyl-6-octenoic acid
FL/FR
diphenyl oxide
FL/FR
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
herbal
red
thyme oil india
FL/FR
red
thyme oil spain
FL/FR
thymol
FL/FR
yerba mate absolute
FL/FR
honey
phenyl pyruvic acid
FL/FR
leathery
castoreum absolute
FL/FR
russian
leather fragrance
FR
russian
leather specialty
FR
medicinal
2,6-
xylenol
FL/FR
minty
piperitenone
FL/FR
mossy
oakmoss concrete
FR
sea resorcylate
FR
veramoss (IFF)
FR
nutty
nutty cyclohexenone
FL/FR
phenolic
anisole
FL/FR
para-
cresol
FL/FR
ortho-
cresol
FR
meta-
cresol
FR
meta-
cresyl acetate
FL/FR
ortho-
cresyl isobutyrate
FL/FR
2,3-
dimethyl benzofuran
FL/FR
para-alpha-
dimethyl styrene
FL/FR
ortho-
guaiacol
FL/FR
2'-
hydroxyacetophenone
FL/FR
methyl benzoate
FL/FR
4-
methyl-2,6-dimethoxyphenol
FL/FR
piper betle leaf oil
FR
2-
propyl phenol
FL/FR
4-
propyl phenol
FL/FR
4-
vinyl phenol
FL/FR
2,5-
xylenol
FL/FR
2,3-
xylenol
FL/FR
smoky
beech wood creosote
FL/FR
birch tar oil
FL/FR
cade oil
FR
2,6-
dimethoxyphenol
FL/FR
alpha-
ethoxy-ortho-cresol
FL/FR
4-
ethyl phenol
FL/FR
propyl paraben
CS
pyroligneous acids
FL/FR
pyroligneous acids hickory
FL/FR
spicy
clove bud absolute
FL/FR
cubeb oil
FL/FR
4-
ethyl guaiacol
FL/FR
4-
methyl guaiacol
FL/FR
methyl isoeugenol
FL/FR
pepper tree berry oil
FL/FR
zingerone
FL/FR
tobacco
methyl benzoxole
FL/FR
vanilla
ortho-
dimethyl hydroquinone
FL/FR
ethyl vanillin hexylene glycol acetal
FR
vanilla cresol
FR
woody
cedarwood oil china
FR
guaiacwood acetates
FR
guaiacwood extract acetate
FR
guaiacyl acetate
FL/FR
(-)-
guaiol
FR
gurjun balsam oil
FR
methyl sandal
FR
beta-
thujaplicin
FR
For Flavor
No flavor group found for these
benzyl disulfide
FL
birch tar oil
FL/FR
chavicol
FL
ortho-
cresyl isobutyrate
FL/FR
2,4-
dihydroxybenzoic acid
FL
2,6-
dimethoxy-4-vinyl phenol
FL
ortho-
dimethyl hydroquinone
FL/FR
alpha-
ethoxy-ortho-cresol
FL/FR
3-
methyl crotonic acid
FL
1-
methyl pyrrole
FL
4-
methyl salicylaldehyde
FL
piperitenone
FL/FR
prenyl mercaptan
FL
2-
propyl phenol
FL/FR
4-
propyl phenol
FL/FR
para-
salicylic acid
FL
seaweed absolute (fucus vesiculosus et serratus)
FL/FR
acidic
acidic
levulinic acid
FL/FR
anisic
ortho-
anisaldehyde
FL/FR
ortho-
methyl acetophenone
FL/FR
aromatic
anisole
FL/FR
para-
cresyl acetate
FL/FR
burnt
bacon dithiazine
FL
rum ether
FL/FR
2,6-
xylenol
FL/FR
chemical
2,3-
dimethyl benzofuran
FL/FR
coffee
coffee distillates
FL
furfuryl mercaptan
FL/FR
coumarinic
phthalide
FL/FR
creamy
para-
vanillyl alcohol
FL/FR
fishy
3-
penten-2-one
FL
floral
3,7-
dimethyl-6-octenoic acid
FL/FR
fruity
benzyl alcohol
FL/FR
dimethyl anthranilate
FL/FR
ethyl 3-hydroxyhexanoate
FL/FR
meta-
tolualdehyde
FL/FR
green
diphenyl oxide
FL/FR
herbal
red
thyme oil india
FL/FR
red
thyme oil spain
FL/FR
yerba mate absolute
FL/FR
leathery
castoreum absolute
FL/FR
licorice
estragole
FL/FR
meaty
4-
allyl-2,6-dimethoxyphenol
FL
2,6-
dimethyl thiophenol
FL
phenyl mercaptan
FL
ortho-
thioguaiacol
FL
medicinal
dextro-
camphor
FL/FR
2,6-
dimethoxyphenol
FL/FR
musty
2-
ethoxythiazole
FL
2,5-
xylenol
FL/FR
naphthyl
2'-
hydroxyacetophenone
FL/FR
nutty
1-
ethyl-2-acetyl pyrrole
FL
methyl benzoxole
FL/FR
nutty cyclohexenone
FL/FR
onion
2-
methyl-1,3-dithiolane
FL
phenolic
para-
cresol
FL/FR
meta-
cresyl acetate
FL/FR
guaiacyl phenyl acetate
FL/FR
methyl benzoate
FL/FR
4-
methyl-2,6-dimethoxyphenol
FL/FR
phenyl pyruvic acid
FL/FR
thymol
FL/FR
4-
vinyl phenol
FL/FR
2,3-
xylenol
FL/FR
powdery
ortho-
acetanisole
FL/FR
rummy
vanillyl ethyl ether
FL/FR
smoky
beech wood creosote
FL/FR
4-
ethyl phenol
FL/FR
pyroligneous acids
FL/FR
pyroligneous acids hickory
FL/FR
dextro-
xylose
FL
solvent
methyl phenyl sulfide
FL
spicy
sumatra
benzoin absolute
FL/FR
chipotle chili oleoresin
FL
clove bud absolute
FL/FR
cubeb oil
FL/FR
para-alpha-
dimethyl styrene
FL/FR
methyl isoeugenol
FL/FR
pepper tree berry oil
FL/FR
para-
tolualdehyde
FL/FR
zingerone
FL/FR
vanilla
4-
methyl guaiacol
FL/FR
vegetable
tyramine
FL
woody
amyris wood oil
FL/FR
4-
ethyl guaiacol
FL/FR
ginseng distillates
FL
ortho-
guaiacol
FL/FR
guaiacyl acetate
FL/FR
quercus alba chips extract
FL
 
Potential Uses:
 creosote
 
Occurrence (nature, food, other):note
 bonito
Search PMC Picture
 whiskey
Search Picture
 
Synonyms:
 azoene fast orange GR base
 azoene fast orange GR salt
 azofix orange GR salt
 azogene fast orange GR
 brentamine fast orange GR base
 brentamine fast orange GR salt
 C.I. azoic diazo component 6
o-cumenol
ortho-cumenol
 cumenol, o-
 devol orange B
 devol orange salt B
 diazo fast orange GR
 fast orange base GR
 fast orange base JR
 fast orange GR base
 fast orange GR salt
 fast orange O base
 fast orange O salt
 fast orange salt GR
 fast orange salt JR
 hiltonil fast orange GR base
 hiltosal fast orange GR salt
 hindasol orange GR salt
1-hydroxy-2-isopropyl benzene
1-hydroxy-2-isopropylbenzene
o-hydroxycumene
ortho-hydroxycumene
2-(1-methyl ethyl) phenol
2-(1-methylethyl)phenol
 orange base ciba II
 orange base IRGA II
 orange GRS salt
 orange salt ciba II
 orange salt IRGA II
 phenol, 2-(1-methylethyl)-
 phenol, 2-isopropyl-
 phenol, o-isopropyl-
 prodox 131
2-propan-2-ylphenol
 propofol imp. C
o-isopropyl phenol
ortho-isopropyl phenol
2-(iso-propyl)phenol
2-isopropylphenol
o-isopropylphenol
ortho-isopropylphenol
 
 
Notes:
Flavouring ingredient
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy