bacon dithiazine
Used as a food additive [EAFUS]
  • Alfrebro
    • Alfrebro LLC
      Let's get reacquainted
      Building great taste with aroma chemicals, extracts, and distillates
      The Alfrebro brand was established in the early 1900s by Alex Fries & Brothers, a Cincinnati Flavor Company. In 1980, the brand was re-launched as an aroma chemical manufacturer. Since its inception, Alfrebro’s primary focus has been to provide quality natural and high value synthetic chemicals.
      Email: Sarah Forbis
      Email: Sales
      Voice: 513-539-3021
      Fax: 513-539-7372
      US Voice: 513-539-7373
  • Blue Marble Biomaterials
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve and our roster of products and services continues to grow with us. Personal care ingredients now include a substantial array of luxury and exotic components. Substantial inroads have been made in the nutraceutical and resins markets, with a growing roster of versatile and unique ingredients. And we continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions.
      Email: Sales
      Voice: 203-299-3220
      Fax: 203-299-1355
      Products List: View
  • DeLong Chemicals America
    • DeLong Chemicals America
      Custom Manufacturing
      Supplier of aroma chemicals, pharmaceutical and specialty chemical intermediates.
      DeLong Chemicals America, LLC is an extension of Shijiazhuang Lida Chemical Co, Ltd to North America, a leading supplier and manufacturer of aroma chemicals, serving the industries of food, tobacco and perfume, while also providing intermediates, custom synthesis and custom manufacturing for pharmaceutical and specialty chemical industries.
      US Email: Customer Service
      US Email: Sales
      US Voice: (203) 271-9017
      New products
      9939 2,4,6-Triisobutyl-1,3,5-dithiazine, Kosher
  • Frutarom
    • Frutarom Ltd
      Discover Our Passion
      Your preferred partner for flavour and fragrance success.
      At Frutarom, we take pride in our expertise and knowledge of Flavour & Fragrance Ingredients and our thorough understanding of the needs of Flavourists, Perfumers and Food Technologists. Working closely with our customers we have a strong track record of providing unique solutions to fulfil requirements.
      US Email: Info- USA
      Email: Info - UK
      Voice: +44 (0) 1429 863 222
      US Voice: +1 513 870 4900
      Products List: View
      1NCT1876 2,4,6-TRIISOBUTYL-5,6-DIHYDRO-1,3,5-DITHIAZINE NI, Kosher
      Suggested Uses: Chocolate, Meat
  • Natural Advantage
    • Natural Advantage
      Manufacturer of natural flavor ingredients
      With over 25 years experience in the flavor and food ingredient industries.
      Natural Advantage was formed over seventeen years ago to supply the growing demand for natural food and flavor ingredients. We employ a wide range of multi-disciplined scientists who are dedicated to high quality service, customer satisfaction and creating an outstanding value for our clients.
      Email: Info
      Email: Customer service
      Voice: 318-215-1456
      Fax: 318-335-1579
      What We Do
      Products List: View
      Bacon Dithiazine Nat, 10% in OH
      Bacon Dithiazine Nat, 10% in Triac
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      20-74000 2,4,6-TRIISOBUTYL-5,6-DIHYDRO-4H-1,3,5-DITHIAZINE, Kosher
  • Symrise
    • Symrise AG
      Always Insiring More
      Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.
      We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success.
      US Email: Life Essentials
      Email: Aroma Molecules
      Voice: +49 5531 90 0
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      600082 Triisobutyl dihydrodithiazine

      Useful in: savory allium, savory meat.
      173630 Triisobutyl dihydrodithiazine natural 15% VTG

      Useful in: savory allium, savory meat
  • Taytonn
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
      Email: Info
      Email: Sales
      Voice: + 65 - 6861 8113
      Fax: + 65 - 6861 8115
Synonyms   Articles   Notes   Search
2,4,6-tris(2-methylpropyl)-1,3,5-dithiazinane (Click)
CAS Number: 74595-94-1Picture of molecule
FDA UNII: Z24510S94G
Nikkaji Web: J2.571.049E
XlogP3-AA: 6.40 (est)
Molecular Weight: 289.54907000
Formula: C15 H31 N S2
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: JECFA evaluated 2,4,6-triisobutyl-5,6-dihydro-4H-1,3,5-dithiazine (CASrn as in Register). (R)- or (S)- enantiomer not specified by CASrn in Register. According to JECFA: Min. assay value is 95 % (mixture of 3 stereoisomers). Mixture of diastereoisomers, each of them racemic (EFFA, 2013b).
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
JECFA Food Flavoring: 1048  2,4,6-triisobutyl-5,6-dihydro-4H-1,3,5-dithiazine
Flavis Number: 15.113 (Old)
DG SANTE Food Flavourings: 15.113  5,6-dihydro-2,4,6-tris(2-methyl propyl)4H-1,3,5-dithiazine
FEMA Number: 4017  2,4,6-triisobutyl-5,6-dihydro-4H-1,3,5-dithiazine
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Physical Properties:
Appearance: pale yellow to yellow crystals (est)
Assay: 95.00 to 100.00 % sum of isomers
Food Chemicals Codex Listed: No
Melting Point: 33.00 to  35.00 °C. @ 760.00 mm Hg
Boiling Point: 385.23 °C. @ 760.00 mm Hg (est)
Flash Point: 210.00 °F. TCC ( 98.89 °C. )
logP (o/w): 6.081 (est)
Soluble in:
 propylene glycol
 water, 2.184 mg/L @ 25 °C (est)
Insoluble in:
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Organoleptic Properties:
Odor Type: meaty
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 meaty  smoky  bacon  
Odor Description:
at 0.10 % in propylene glycol. 
meaty smoked bacon
 burnt  roasted  bacon  
Taste Description:
burnt roasted crispy bacon
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Cosmetic Information:
None found
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Odor: Pork, Fatty, Meaty
Anhui Suzhou Jinli Aromatic Chemicals
Odor: burnt wood, burnt sulfuric acid. salty beef, chicken, beef and smoked meat
Blue Marble Biomaterials
Bacon Dithiazine - Natural
US/EU Natural, Food Grade, Non-GMO, Vegan
Odor: smoky, meaty, crispy, bacon
Flavor: meaty, burnt, crispy, bacon
BOC Sciences
For experimental / research use only.
Charkit Chemical
DeLong Chemicals America
2,4,6-Triisobutyl-1,3,5-dithiazine, Kosher
NI, Kosher
Odor: Bacon, Chocolate, Meaty
Use: Suggested Uses: Chocolate, Meat
Natural Advantage
Bacon Dithiazine Nat, 10% in OH
Natural Advantage
Bacon Dithiazine Nat, 10% in Triac
Penta International
Shijiazhuang Donglian Nankai Aroma Chemicals
Odor: Saute squid and saute sesame
Triisobutyl dihydrodithiazine natural 15% VTG
Flavor: burnt, roasted, crispy bacon
Useful in: savory allium, savory meat
Triisobutyl dihydrodithiazine
Flavor: burnt, roasted, crispy bacon
Useful in: savory allium, savory meat.
Odor: Chocolate, Meaty
Tengzhou Xiang Yuan Aroma Chemicals
Wujiang CIYUN Flavor & Fragrance
2,4,6-Trisobutyl-1,3,5-dithiazine ≥70.0%
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Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavoring agents
Recommendation for bacon dithiazine usage levels up to:
 not for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU): 2.40 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 2.60 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 20
Click here to view publication 20
 average usual ppmaverage maximum ppm
baked goods: 0.200002.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: 0.100001.00000
cheese: --
chewing gum: --
condiments / relishes: 0.100001.00000
confectionery froastings: --
egg products: --
fats / oils: 0.200002.00000
fish products: 0.040000.40000
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 0.200002.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 0.100001.00000
milk products: --
nut products: --
other grains: 0.040000.40000
poultry: --
processed fruits: --
processed vegetables: 0.040000.40000
reconstituted vegetables: 0.040000.40000
seasonings / flavors: --
snack foods: 0.040000.40000
soft candy: --
soups: 0.100001.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 21: Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29. Miscellaneous substances from chemical group 30. (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 76, (FGE.76)[1] - Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29, miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 21, Revision 1 (FGE.21Rev1): Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 Miscellaneous substances from chemical group 30
View page or View pdf
Statement on List of Representative Substances for Testing. The current Statement lays down a list of substances in sub-groups with representative substances for which additional data are required prior to their evaluation through the Procedure (Regulation (EC) No 1565/2000).
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 21, Revision 4 (FGE.21Rev4): Thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 76, Revision 1 (FGE.76Rev1): Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21Rev3
View page or View pdf
Safety and efficacy of thiazoles, thiophene and thiazoline belonging to chemical group 29 when used as flavourings for all animal species
View page or View pdf
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 46941523
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0074595941
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NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 46941523
Pubchem (sid): 131325381
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): HMDB32221
FooDB: FDB009292
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
For Odor
roasted arabica coffee bean oil CO2 extractFL/FR
 furfuryl mercaptanFL/FR
4-methyl nonanoic acidFL/FR
3-acetyl pyridineFL/FR
 pyroligneous acidsFL/FR
4-ethyl guaiacolFL/FR
For Flavor
No flavor group found for these
 amyl mercaptanFL
1,6-hexane dithiolFL
2-methyl quinoxalineFL
2,5-dimethyl furanFL
roasted arabica coffee bean oil CO2 extractFL/FR
 furfuryl mercaptanFL/FR
4-methyl nonanoic acidFL/FR
 garlic oleoresinFL
3-acetyl pyridineFL/FR
2-ethyl benzene thiolFL
3-(methyl thio) propyl mercaptoacetateFL
 hexyl mercaptanFL
 prosopis juliflora wood extractFL
 pyroligneous acidsFL/FR
4-ethyl guaiacolFL/FR
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Potential Uses:
 meat smoked meat 
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Occurrence (nature, food, other): note
 found in nature
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 bacon thiazole (Alfrebro)
5,6-dihydro-2,4,6-tris(2-methyl propyl)4H-1,3,5-dithiazine
 triisobutyl dihydrodithiazine
 triisobutyl dihydrodithiazine natural 15% VTG
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 None found yet.
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