citrus grandis fruit extract
extract of the fruit of the grapefruit, citrus grandis, rutaceae
None found
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Name: citrus grandis fruit extract
CAS Number: 90045-43-5 
ECHA EC Number: 289-904-6
Name: citrus grandis fruit oil
CAS Number: 8016-20-4 
Category: cosmetic, flavor and fragrance agents, dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Regulation:
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
Odor Type: citrus
Odor Strength: medium
Odor Description:
at 100.00 %. 
Taste Description:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: astringents
perfuming agents
skin conditioning
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grapefruit fruit extract
Grau Aromatics
H. Erhard Wagner
PhytoVital Grapefruit
Odor: characteristic
Use: PhytoVital - Grapefruit is obtained through a gentle extraction of the whole fruits of citrus decumana or citrus maxima. This aromatic fruits contains carbohydrates like fructose, dextrose, inositol, mannitol and different organic acids, especially fruit acids, like malic acid, citric acid, etc. Different kinds of oligosaccharides, flavonoids, amino acids and vitamins (vitamin B 6, niacinamide) are as well found together with mineral salts. Grapefruit has a strong skin hydrating effect due to its polysaccharide/amino acid complex. Young attractive skin is characterized by elasticity and softness associated with proper skin hydration. PhytoVital - Grapefruit is a restitutive product for the hydration of the skin, contributing to the natural moisturizing factors normally found below the lipid layer. Fruit acids (specially the AHA - acids) found in the extract are having a light peeling effect on the skin, contributing to its renewal and giving a healthy appeal. Because of the presence of these substances, grapefruit extracts also have multiple uses in the Cosmetics Industry. Included are all products which support the regeneration of dry or tired skin. These are, for example, facial creams, lotions and masks, in facial foam masks, shampoos and body lotions. PhytoVital - Grapefruit should be stored at room temperature under normal conditions. Low temperature can cause cloudiness, but this does not influence the activity and it regains its normal appearance at temperatures exceeding 15°C. PhytoVital - Grapefruit is stable at low temperature in the original unopened container for a minimum of 12 months. Sedimentation may occur but has no negative influence on the material either. PhytoVital - Extracts are finalized due to a special extraction process.
Lipotec USA
Actiphyte® of Grapefruit Extract
Grapefruit Extract
NAT arom®, liquid or powder forms
SRS Aromatics
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 723, 1974.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 723, 1974.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic, flavor and fragrance agents, dietary supplements
IFRA Critical Effect: Phototoxicity
IFRA fragrance material specification:
 Where the bergapten (5-methoxypsoralen) content of all relevant oils present in a compound has been determined, it is recommended that for applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, the total level of bergapten in the consumer products should not exceed 0.0015% (15 ppm). This is equivalent to 0.0075% (75 ppm) in a fragrance compound used at 20% in the consumer product. Where the level of bergapten has not been determined by appropriate methods, the limits specified in the guidelines on individual oils should apply. In those cases, where such oils are used in combination with other phototoxic ingredients, the additive effect has to be taken into consideration and the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100.
IFRA: View Standard
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Safety References: search
Daily Med: search
NLM Hazardous Substances Data Bank: Search
Cancer Citations: Search
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EPA Substance Registry Services (TSCA): 90045-43-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 citrus grandis fruit extract
Chemidplus: 090045435
 citrus grandis fruit oil
Chemidplus: 008016204
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 citrus grandis fruit extract
Canada Domestic Sub. List: 90045-43-5
Pubchem (sid): 3783477
 citrus grandis fruit oil
Canada Domestic Sub. List: 8016-20-4
Pubchem (sid): 167279
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Other Information:
Household Products: Search
Wikipedia: View
Wikipedia2: View2
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
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 citrus maxima fruit extract
 extract of the fruit of the grapefruit, citrus grandis, rutaceae
actiphyte of grapefruit extract
 grapefruit extract HS 1807 AT (Grau)
 grapefruit fruit extract (citrus grandis)
 pomelo fruit extract
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PubMed: Effects of pectinase clarification treatment on phenolic compounds of pummelo (Citrus grandis l. Osbeck) fruit juice.
PubMed: Synergistic Effect of Sodium Chlorite and Edible Coating on Quality Maintenance of Minimally Processed Citrus grandis under Passive and Active MAP.
PubMed: Flavonoid profiles of immature and mature fruit tissues of Citrus grandis Osbeck (Dangyuja) and overall contribution to the antioxidant effect.
PubMed: Transcriptomic analysis of differentially expressed genes in an orange-pericarp mutant and wild type in pummelo (Citrus grandis).
PubMed: De novo transcriptome assembly of pummelo and molecular marker development.
PubMed: Comparison of chemical profiling and antioxidant activities of fruits, leaves, branches, and flowers of Citrus grandis 'Tomentosa'.
PubMed: Simultaneous purification of limonin, nomilin and isoobacunoic acid from pomelo fruit (Citrus grandis) segment membrane.
PubMed: Flavonoid profiles of immature and mature fruit tissues of Citrus grandis Osbeck (Dangyuja) and overall contribution to the antioxidant effect.
PubMed: Flavonoid composition and antioxidant activities of Chinese local pummelo (Citrus grandis Osbeck.) varieties.
PubMed: Systematic chemical profiling of Citrus grandis 'Tomentosa' by ultra-fast liquid chromatography/diode-array detector/quadrupole time-of-flight tandem mass spectrometry.
PubMed: Effects of granulation on organic acid metabolism and its relation to mineral elements in Citrus grandis juice sacs.
PubMed: Integration of metabolomics and subcellular organelle expression microarray to increase understanding the organic acid changes in post-harvest citrus fruit.
PubMed: Cultivar variations in antioxidant and antihyperlipidemic properties of pomelo pulp (Citrus grandis [L.] Osbeck) in Thailand.
PubMed: A water-alcohol extract of Citrus grandis whole fruits has beneficial metabolic effects in the obese Zucker rats fed with high fat/high cholesterol diet.
PubMed: Chemical composition and sensory profile of pomelo (Citrus grandis (L.) Osbeck) juice.
PubMed: Study on impurities in naringin extracted from Citrus grandis 'tomentosa'.
PubMed: Isolation and characterization of activators of ERK/MAPK from citrus plants.
PubMed: Volatile constituents of wild citrus Mangshanyegan (Citrus nobilis Lauriro) peel oil.
PubMed: Comparative transcriptomics and proteomics analysis of citrus fruit, to improve understanding of the effect of low temperature on maintaining fruit quality during lengthy post-harvest storage.
PubMed: Sex pheromone components and control of the citrus pock caterpillar, Prays endocarpa, found in the Mekong Delta of Vietnam.
PubMed: Racemization at C-2 of naringin in pummelo (Citrus grandis) with increasing maturity determined by chiral high-performance liquid chromatography.
PubMed: Major phytochemical composition of 3 native Korean citrus varieties and bioactive activity on V79-4 cells induced by oxidative stress.
PubMed: Classification and prediction of free-radical scavenging activities of dangyuja (Citrus grandis Osbeck) fruit extracts using (1)H NMR spectroscopy and multivariate statistical analysis.
PubMed: Antioxidant content and free radical scavenging ability of fresh red pummelo [Citrus grandis (L.) Osbeck] juice and freeze-dried products.
PubMed: A pthA homolog from Xanthomonas axonopodis pv. citri responsible for host-specific suppression of virulence.
PubMed: [Experimental studies on antitussive, expectorant and antiasthmatic effects of extract from Citrus grandis var. tomentosa].
PubMed: Phyto-saponins as a natural adjuvant for delivery of agromaterials through plant cuticle membranes.
PubMed: Volatile constituents of redblush grapefruit (Citrus paradisi) and pummelo (Citrus grandis) peel essential oils from Kenya.
PubMed: [Study on heavy metals in growing area soils and young fruit of Citrus grandis 'Tomentosa'].
PubMed: Microdissection and molecular manipulation of single chromosomes in woody fruit trees with small chromosomes using pomelo (Citrus grandis) as a model. II. Cloning of resistance gene analogs from single chromosomes.
PubMed: Microdissection and molecular manipulation of single chromosomes in woody fruit trees with small chromosomes using pomelo (Citrus grandis) as a model. I. Construction of single chromosomal DNA libraries.
PubMed: [Structure determination of the constituents from Citrus grandis Osbeck].
PubMed: Propagation of 'Nam Roi' pummelo (Citrus grandis (L.) Osbeck.) by cuttings.
PubMed: Leaf photosynthesis of 'Cat Hoa Loc' mango (Mangifera indica L.) and 'Nam Roi' pummelo (Citrus grandis (L.) Osbeck.) in the rainy season.
PubMed: Effect of honey on naringin absorption from a decoction of the pericarps of Citrus grandis.
PubMed: Citrus and Prunuscopia-like retrotransposons.
PubMed: Juvenile-Specific Localization and Accumulation of a Rhamnosyltransferase and Its Bitter Flavonoid in Foliage, Flowers, and Young Citrus Fruits.
PubMed: Linkage of restriction fragment length polymorphisms and isozymes in Citrus.
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