curled parsley leaf oil cuba
essential oil obtained from the leaves of the parsley, petroselinum crispum, umbelliferae cuba
 
Notes:
Also known as Parsley Leaf Oil, this oil is produced by steam distillation of the top of the flowering parsley plant, Petroselinum Sativum. Parsley is a native of the eastern Mediterranean countries and it has been known and used in food for more than 2000 years. The plant seems to have come to England as late as 1548 and to the U.S.A. about a century later. For those who know parsley, it might be easier to describe the odor of the oil as being very similar to that of the fresh cut herb. Parsley Herb Oil is used very rarely, if used at all, in perfumery. tsca definition 2008: extractives and their physically modified derivatives. petroselinum savitum, umbelliferae.
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Name: petroselinum crispum mill. leaf oil
CAS Number: 8000-68-8 
MDL: MFCD00241319
Also Contains: petroselinum crispum seed extract
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2836  curled parsley leaf oil cuba
FDA Mainterm: PARSLEY, OIL (PETROSELINUM SPP.)
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Appearance: orange amber clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.90800 to 0.94000 @  25.00 °C.
Pounds per Gallon - (est).: 7.555 to  7.822
Refractive Index: 1.50300 to 1.53000 @  20.00 °C.
Optical Rotation: -9.00 to +1.00
Boiling Point: 290.00 °C. @ 760.00 mm Hg
Flash Point: 122.00 °F. TCC ( 50.00 °C. )
Soluble in:
 alcohol
 water, 27.68 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
Odor Type: herbal
Odor Strength: medium
 herbal  parsley  
Odor Description:
at 100.00 %. 
herbal parsley
 parsley  
Taste Description:
parsley
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: masking agents
perfuming agents
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Suppliers:
 None found
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Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 10 - Flammable.
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
2 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50  3300 mg/kg
Food and Chemical Toxicology. Vol. 21, Pg. 871, 1983.

oral-mouse LD50  1520 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Food and Cosmetics Toxicology. Vol. 13, Pg. 897, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 21, Pg. 871, 1983.

skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 897, 1975.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Phototoxicity
IFRA fragrance material specification:
 The following essential oils contain small amounts of phototoxic furocoumarins. These levels are not high enough to require special restrictions if used alone, but if used in combination with one or the other phototoxic essential oil, attention should be paid that the total level of bergapten (5-MOP) in the consumer product does not exceed 15 ppm. It is the responsibility of fragrance manufacturers to ensure that the level is observed. Typical levels of 5-MOP are the following: Parsley leaf oil - 20 ppm.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
benzyl alcohol Max. Found: <0.50 % and Reason: Sensitization
carvone Max. Found: <0.20 % and Reason: Sensitization
IFRA: View Standard
Recommendation for curled parsley leaf oil cuba usage levels up to:
  2.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3. Update in publication number(s): 24
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: 19.0000024.00000
beverages(nonalcoholic): 1.000002.00000
beverages(alcoholic): 1.000002.00000
breakfast cereal: --
cheese: --
chewing gum: 8000.0000012500.00000
condiments / relishes: 45.0000064.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.900001.00000
fruit ices: -0.25000
gelatins / puddings: 7.0000010.00000
granulated sugar: --
gravies: 2.000006.00000
hard candy: 1000.000001000.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 38.0000063.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: 0.800001.00000
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: 3.000006.00000
soups: 33.0000066.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 8000-68-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 1993
WGK Germany: 2
 petroselinum crispum mill. leaf oil
Chemidplus: 0008000688
RTECS: RW5500000 for cas# 8000-68-8
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References:
 petroselinum crispum mill. leaf oil
Canada Domestic Sub. List: 8000-68-8
Pubchem (sid): 135334239
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.29.6000
 Typical G.C.
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
For Odor
amber
amber
 angelica root oilFL/FR
animal
isobutyl quinolineFR
anise
sweet fennel seed oilFL/FR
anisic
 ocimum basilicum herb oilFL/FR
 ocimum basilicum leaf oil CO2 extractFL/FR
balsamic
 cinnamyl alcoholFL/FR
 cinnamyl formateFL/FR
 guaiyl acetateFL/FR
2-phenyl propyl alcoholFL/FR
camphoreous
 verbenoneFL/FR
caramellic
 fenugreek absoluteFL/FR
citrus
 ocimene quintoxideFL/FR
ethereal
 ethyl 4-pentenoateFL/FR
fatty
(E)-2-octenalFL/FR
floral
 dihydrorose oxideFR
 dimethyl benzyl carbinyl butyrateFL/FR
2,4-dimethyl-3-cyclohexene-1-methanolFR
 geranium oil africaFL/FR
 geranium oil bourbonFL/FR
 geranium oil egyptFL/FR
 hexahydrofarnesyl acetoneFL/FR
 jasmin pyranolFR
isojasmoneFL/FR
(Z)-jasmoneFL/FR
 neryl formateFL/FR
2-pentadecanoneFL/FR
2-pentyl cyclopentanoneFR
 phenyl propyl phenyl acetateFR
isophytolFL/FR
 rose absolute (rosa damascena) bulgariaFL/FR
 rose pyranFR
fruity
 tropical indeneFR
green
isobutyl benzyl carbinolFL/FR
isobutyl heptanoateFL/FR
isobutyl methyl ketoneFL/FR
2-sec-butyl thiazoleFL/FR
 carrot leaf oil (daucus carota ssp.maximus)FR
 heptanal (aldehyde C-7)FL/FR
1-heptanolFL/FR
(Z)-4-hexen-1-olFL/FR
(E)-4-hexen-1-ol 
3-hexenyl 2-methyl butyrateFL/FR
 hexyl hexanoateFL/FR
english ivy leaf absoluteFR
 seaweed absolute (fucus vesiculosus et serratus)FL/FR
herbal
6-acetoxydihydrotheaspiraneFL/FR
alpha-amyl cinnamyl formateFL/FR
 anethum graveolens herb oilFL/FR
 anthemis nobilis flower oil romanFL/FR
 apium graveolens seed oil indiaFL/FR
sweet basil absoluteFL/FR
3-butyl phthalideFL/FR
3-butylidene phthalideFL/FR
(+)-alpha-campholenic aldehydeFL/FR
 carrot seed oil (daucus carota ssp. gummifer hook. fil.) spainFR
 celery ketoneFL/FR
 celery leaf oilFL/FR
 celery seed oil CO2 extractFL/FR
 celery undeceneFR
 coriander oleoresinFL/FR
 daucus carota fruit oilFL/FR
 dill weed oil cubaFL/FR
 dill weed oil reunionFL/FR
 dimethyl benzyl carbinyl formateFL/FR
cis-herbal cyclohexaneFR
 herbal dioxaneFR
 herbal heptaneFR
 hop absoluteFL/FR
 hop oilFL/FR
 levisticum officinale herb oilFL/FR
 levisticum officinale root absoluteFL/FR
 linalyl formateFL/FR
 linalyl octanoateFL/FR
 marigold oil mexicoFL/FR
 melaleuca leucadendron var. cajuputi leaf oilFL/FR
(E)-6-methyl-3-hepten-2-oneFL/FR
 mistletoe absolute 
 nonisyl formateFR
1-octen-3-yl acetateFL/FR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 perillaldehydeFL/FR
3-propylidene phthalideFL/FR
 reseda absoluteFR
 tagete oil CO2 extractFL/FR
 tagete oil rwandaFL/FR
 tagete oil south africaFL/FR
 theaspiraneFL/FR
 thyme absoluteFL/FR
 tricyclodecyl acetateFR
 viridiflorolFL/FR
 wormwood oil americaFL/FR
minty
 betula lenta bark oil americaFL/FR
(-)-isopulegolFL/FR
mossy
 oakmoss phenolFR
 treemoss absoluteFR
pine
 dipentene terpene hydrocarbon byproductsFR
spicy
isobutyl angelateFL/FR
 carrot weed oilFL/FR
 cinnamaldehyde dimethyl acetalFL/FR
(-)-cubenolFL/FR
 cumin seed absoluteFL/FR
 cuminaldehydeFL/FR
black currant bud absoluteFL/FR
isocyclogeraniol (IFF)FR
 levisticum officinale root oilFL/FR
2-octanolFL/FR
sulfurous
 lychee mercaptan acetateFL/FR
terpenic
D-(+)-beta-pineneFL/FR
tonka
 whiskey lactoneFL/FR
woody
 amber dodecaneFR
alpha-thujene 
 verdoxanFR
 
For Flavor
 
No flavor group found for these
6-acetoxydihydrotheaspiraneFL/FR
alpha-amyl cinnamyl formateFL/FR
isobutyl heptanoateFL/FR
3-butyl phthalideFL/FR
4-butyl thiazoleFL
2-sec-butyl thiazoleFL/FR
3-butylidene phthalideFL/FR
(+)-alpha-campholenic aldehydeFL/FR
 celery ketoneFL/FR
 cinnamyl formateFL/FR
 dimethyl benzyl carbinyl formateFL/FR
 ethyl 4-pentenoateFL/FR
 fig leaf absoluteFL
 guaiyl acetateFL/FR
 heptanal (aldehyde C-7)FL/FR
(E,E)-2,4-hexadien-1-olFL
 hexahydrofarnesyl acetoneFL/FR
 linalyl formateFL/FR
 melaleuca leucadendron var. cajuputi leaf oilFL/FR
(E)-6-methyl-3-hepten-2-oneFL/FR
 mistletoe absolute 
2-octanolFL/FR
2-phenyl propyl alcoholFL/FR
D-(+)-beta-pineneFL/FR
2-propyl thiazoleFL
(-)-isopulegolFL/FR
 rose absolute (rosa damascena) bulgariaFL/FR
 seaweed absolute (fucus vesiculosus et serratus)FL/FR
alpha-thujene 
 verbenoneFL/FR
 viridiflorolFL/FR
alliaceous
 cyclopentyl mercaptanFL
 truffle sulfideFL
anise
sweet fennel seed oilFL/FR
balsamic
isobutyl benzyl carbinolFL/FR
caramellic
 fenugreek absoluteFL/FR
cooling
 theaspiraneFL/FR
fatty
(E)-2-octenalFL/FR
2-pentadecanoneFL/FR
floral
 dimethyl benzyl carbinyl butyrateFL/FR
 geranium oil africaFL/FR
 geranium oil bourbonFL/FR
 geranium oil egyptFL/FR
fruity
 hexyl hexanoateFL/FR
 neryl formateFL/FR
 tagete oil CO2 extractFL/FR
 tagete oil rwandaFL/FR
 tagete oil south africaFL/FR
green
 angelica root oilFL/FR
isobutyl angelateFL/FR
isobutyl methyl ketoneFL/FR
 carrot weed oilFL/FR
 cinnamyl alcoholFL/FR
 coriander oleoresinFL/FR
(E,E)-2,4-hexadienalFL
(E)-4-hexen-1-ol 
(Z)-4-hexen-1-olFL/FR
3-hexenyl 2-methyl butyrateFL/FR
isojasmoneFL/FR
 ocimene quintoxideFL/FR
1-octen-3-yl acetateFL/FR
3-propylidene phthalideFL/FR
 sorbyl acetateFL
herbal
 anethum graveolens herb oilFL/FR
 anthemis nobilis flower oil romanFL/FR
 apium graveolens seed oil indiaFL/FR
sweet basil absoluteFL/FR
 celery leaf oilFL/FR
 celery seed oil CO2 extractFL/FR
 celery seed oleoresinFL
 daucus carota fruit oilFL/FR
 dill weed oil cubaFL/FR
 dill weed oil reunionFL/FR
 hop absoluteFL/FR
 hop oilFL/FR
 linalyl octanoateFL/FR
 marigold oil mexicoFL/FR
 ocimum basilicum herb oilFL/FR
 ocimum basilicum leaf oil CO2 extractFL/FR
 origanum oilFL/FR
 origanum oil greeceFL/FR
 thyme absoluteFL/FR
 wormwood oil americaFL/FR
juicy
 lychee mercaptan acetateFL/FR
minty
 betula lenta bark oil americaFL/FR
oily
isophytolFL/FR
solvent
1-heptanolFL/FR
spicy
 cinnamaldehyde dimethyl acetalFL/FR
(-)-cubenolFL/FR
 cumin seed absoluteFL/FR
 cuminaldehydeFL/FR
black currant bud absoluteFL/FR
 levisticum officinale herb oilFL/FR
 levisticum officinale oleoresinFL
 levisticum officinale root absoluteFL/FR
 levisticum officinale root oilFL/FR
 perillaldehydeFL/FR
woody
(Z)-jasmoneFL/FR
 whiskey lactoneFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 parsley
Search Trop  Picture
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Synonyms:
 apium crispum leaf oil cuba
 apium petroselinum leaf oil cuba
 carum petroselinum leaf oil cuba
 essential oil obtained from the leaves of the parsley, petroselinum crispum, umbelliferae cuba
curled parsley leaf oil cuba
 petroselinum crispum leaf oil cuba
 petroselinum hortense leaf oil cuba
 petroselinum petroselinum leaf oil cuba
 petroselinum sativum leaf oil cuba
 petroselinum vulgare leaf oil cuba
 wydleria portoricensis leaf oil cuba
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Articles:
PubMed: Influence of microwave frequency electromagnetic radiation on terpene emission and content in aromatic plants.
PubMed: Optimization of extraction conditions of some polyphenolic compounds from parsley leaves (Petroselinum crispum).
PubMed: Characterization of the endogenous enzymatic hydrolyses of Petroselinum crispum glycosides: determined by chromatography upon their sugar and flavonoid products.
PubMed: Morphological and biochemical changes in two parsley varieties upon water stress.
PubMed: Biochemical and haematological assessment of toxic effects of the leaf ethanol extract of Petroselinum crispum (Mill) Nyman ex A.W. Hill (Parsley) in rats.
PubMed: Anticancer Activity of Certain Herbs and Spices on the Cervical Epithelial Carcinoma (HeLa) Cell Line.
PubMed: Sensory characteristics and volatile profiles of parsley ( Petroselinum crispum [Mill.] Nym.) in correlation to resistance properties against Septoria Blight ( Septoria petroselini ).
PubMed: Multilocus sequence typing of Pseudomonas syringae sensu lato confirms previously described genomospecies and permits rapid identification of P. syringae pv. coriandricola and P. syringae pv. apii causing bacterial leaf spot on parsley.
PubMed: Protective effects of Petroselinum crispum (Mill) Nyman ex A. W. Hill leaf extract on D-galactose-induced oxidative stress in mouse brain.
PubMed: DNA amounts of roses (Rosa L.) and their use in attributing ploidy levels.
PubMed: Changes in carotenoid content and distribution in living plant tissue can be observed and mapped in situ using NIR-FT-Raman spectroscopy.
PubMed: Chemical stimulants of leaf-trenching by cabbage loopers: natural products, neurotransmitters, insecticides, and drugs.
PubMed: The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro.
PubMed: Potyviruses, novel and known, in cultivated and wild species of the family Apiaceae in Australia.
PubMed: Increases in Cytosolic Ca2+ in Parsley Mesophyll Cells Correlate with Leaf Senescence.
PubMed: Two differentially regulated class II chitinases from parsley.
PubMed: Transcriptional activation of the parsley chalcone synthase promoter in heterologous pea and yeast systems.
PubMed: Extensive reprogramming of primary and secondary metabolism by fungal elicitor or infection in parsley cells.
PubMed: Identification of UV/blue light-response elements in the Arabidopsis thaliana chalcone synthase promoter using a homologous protoplast transient expression system.
PubMed: Rapid, transient, and highly localized induction of plastidial omega-3 fatty acid desaturase mRNA at fungal infection sites in Petroselinum crispum.
PubMed: Biphasic Temporal and Spatial Induction Patterns of Defense-Related mRNAs and Proteins in Fungus-Infected Parsley Leaves.
PubMed: Differential regulation and tissue-specific distribution of enzymes of phenylpropanoid pathways in developing parsley seedlings.
PubMed: Gene structure and in situ transcript localization of pathogenesis-related protein 1 in parsley.
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