EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

3-methyl pyridine
pyridine, 3-methyl-

Supplier Sponsors

Name:3-methylpyridine
CAS Number: 108-99-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:203-636-9
FDA UNII: B083J4KF7F
Nikkaji Web:J5.085G
Beilstein Number:0001366
MDL:MFCD00006402
CoE Number:11801
XlogP3:1.20 (est)
Molecular Weight:93.12879000
Formula:C6 H7 N
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Perfumer and Flavorist:Search
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EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Flavourings:14.135 3-methylpyridine
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.95300 to 0.95900 @ 25.00 °C.
Pounds per Gallon - (est).: 7.930 to 7.980
Refractive Index:1.49000 to 1.50200 @ 20.00 °C.
Melting Point: -19.00 °C. @ 760.00 mm Hg
Boiling Point: 143.00 to 145.00 °C. @ 760.00 mm Hg
Vapor Pressure:6.700000 mmHg @ 25.00 °C. (est)
Vapor Density:3.2 ( Air = 1 )
Flash Point: 97.00 °F. TCC ( 36.11 °C. )
logP (o/w): 1.200
Soluble in:
 alcohol
 water, 2.303e+005 mg/L @ 25 °C (est)
 water, 1.00E+06 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Flavor Type: green
green earthy hazelnut nutty
Taste Description: green earthy hazelnut
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
EMD Millipore
For experimental / research use only.
3-methylpyridine
OQEMA
Beta/Gamma-Picoline
Penta International
3-METHYL PYRIDINE
Santa Cruz Biotechnology
For experimental / research use only.
3-Picoline
Sigma-Aldrich: Aldrich
For experimental / research use only.
3-Picoline 99%
TCI AMERICA
For experimental / research use only.
3-Methylpyridine >98.0%(GC)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
C - Corrosive.
R 10 - Flammable.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R 34 - Causes burns.
S 01/02 - Keep locked up and out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 [sex: M,F] 710 mg/kg
(Birch, 1972b)

oral-rat LD50 [sex: M] 630 mg/kg
(Dow Chemical Company, 1983)

intraperitoneal-mouse LD50 596 mg/kg
(Dow Chemical Company, 1983)

intravenous-mouse LD50 298 mg/kg
(Dow Chemical Company, 1983)

oral-bird - wild LD50 1000 mg/kg
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.

intraperitoneal-mouse LD50 596 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 82, 1946.

intravenous-mouse LD50 298 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 82, 1946.

oral-quail LD50 1000 mg/kg
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.

intraperitoneal-rat LD50 150 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Fundamental and Applied Toxicology. Vol. 5, Pg. 920, 1985.

oral-rat LD50 400 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 841, 1986.

Dermal Toxicity:
skin-guinea pig LD50 1000 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 841, 1986.

skin-rabbit LD50 200 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 841, 1986.

skin-guinea pig LD50 1000 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 841, 1986.

skin-rabbit LDLo 200 mg/kg
LUNGS, THORAX, OR RESPIRATION: PULMONARY EMBOLI GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0534823

Inhalation Toxicity:
inhalation-rat LCLo 11820 mg/m3/5H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS
National Technical Information Service. Vol. OTS0534823

 
Safety in Use Information:
Category:
flavoring agents
Recommendation for 3-methyl pyridine usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.027 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 400 (μg/person/day)
Threshold of Concern:540 (μg/person/day)
Structure Class: II
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 0.400002.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 0.200001.00000
Edible ices, including sherbet and sorbet (03.0): 0.400002.00000
Processed fruit (04.1): 0.400002.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 1.000005.00000
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 0.200001.00000
Bakery wares (07.0): 2.0000010.00000
Meat and meat products, including poultry and game (08.0): 0.200001.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 0.200001.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 0.100000.50000
Foodstuffs intended for particular nutritional uses (13.0): 0.200001.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 0.200001.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): --
Ready-to-eat savouries (15.0): 1.000005.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 0.200001.00000
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 24 (FGE.24): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 Flavouring Group Evaluation 24, Revision 1 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 77 (FGE77) [1] - Consideration of Pyridine, Pyrrole and Quinoline Derivatives evaluated by JECFA (63rd meeting) structurally related to Pyridine, Pyrrole, Indole and Quinoline Derivatives evaluated by EFSA in FGE.24Rev1 (2008)
View page or View pdf

Scientific opinion on Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):108-99-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7970
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 2313
WGK Germany:1
3-methylpyridine
Chemidplus:0000108996
EPA/NOAA CAMEO:hazardous materials
RTECS:108-99-6
 
References:
 3-methylpyridine
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:108-99-6
Pubchem (cid):7970
Pubchem (sid):134973507
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB61887
FooDB:FDB004416
Export Tariff Code:2933.39.1000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
gentiana lutea root extract
FL/FR
citrus
citrus
2-
heptanol
FL/FR
herbal
1-
octen-3-yl acetate
FL/FR
thymyl methyl ether
FL/FR
licorice
glycyrrhiza glabra root extract
FL/FR
nutty
2-
methyl-3-propyl pyrazine
FL/FR
2,4,5-
trimethyl oxazole
FL/FR
yeasty
2-
octen-4-one
FL/FR
For Flavor
astringent
2-
methyl pyridine
FL
burnt
2,4,5-
trimethyl oxazole
FL/FR
earthy
2-
methyl-3-propyl pyrazine
FL/FR
fruity
2-
heptanol
FL/FR
green
gentiana lutea root extract
FL/FR
1-(5-
methyl-2-furyl) propan-1-one
FL
1-
octen-3-yl acetate
FL/FR
propylene glycol acetone ketal
FL
licorice
glycyrrhiza glabra root extract
FL/FR
musty
thymyl methyl ether
FL/FR
nutty
almond hazelnut flavor
FL
2,5-
diethyl-3-methyl pyrazine
FL
2-
ethyl-6-methyl pyrazine
FL
vanilla
vanilla hazelnut flavor
FL
vegetable
2-
octen-4-one
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 beer - 0.0008 mg/kg
Search PMC Picture
 coffee - 1.3 mg/kg
Search PMC Picture
 orange pericarp oil
Search Trop Picture
 tea leaf
Search Trop Picture
 whiskey - up to 0.0006 mg/kg
Search Picture
 
Synonyms:
meta-methyl pyridine
.beta.-methylpyridine
3-methylpyridine
beta-methylpyridine
m-methylpyridine
.beta.-picoline
3-picoline
beta-picoline
m-picoline
meta-picoline
 pyridine, 3-methyl-
 

Articles:

US Patents:3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines
PubMed:Solvation dependence of valence electronic states of water diluted in organic solvents probed by soft X-ray spectroscopy.
US Patents:4,005,227 - Flavoring agent
PubMed:Tuning the cytotoxic properties of new ruthenium(III) and ruthenium(II) complexes with a modified bis(arylimino)pyridine Schiff base ligand using bidentate pyridine-based ligands.
PubMed:Membrane formation by preferential solvation of ions in mixture of water, 3-methylpyridine, and sodium tetraphenylborate.
PubMed:Utilizing proton transfer to produce molecular salts in bromanilic acid substituted-pyridine molecular complexes - predictable synthons?
PubMed:An emitting Hofmann-type compound: evidence for interlayer aurophilic interactions.
PubMed:Deep-blue phosphorescence from perfluoro carbonyl-substituted iridium complexes.
PubMed:¹H-MAS-NMR chemical shifts in hydrogen-bonded complexes of chlorophenols (pentachlorophenol, 2,4,6-trichlorophenol, 2,6-dichlorophenol, 3,5-dichlorophenol, and p-chlorophenol) and amine, and H/D isotope effects on ¹H-MAS-NMR spectra.
PubMed:trans-Dibromidobis(3-methyl-pyridine-κN)copper(II).
PubMed:Colloidal aggregation in microgravity by critical Casimir forces.
PubMed:(Acetato-κ(2)O,O')(acetato-κO)bis(2-amino-3-methyl-pyridine-κN(1))cobalt(II).
PubMed:Toward unidirectional switches: 2-(2-Hydroxyphenyl)pyridine and 2-(2-methoxyphenyl)pyridine derivatives as pH-triggered pivots.
PubMed:Bis(2-amino-3-methyl-pyridine-κN(1))dichloridomercury(II).
PubMed:Metallacycles of cadmium, mercury dicarboxylates.
PubMed:Effects of anthropogenic inputs on the organic quality of urbanized streams.
PubMed:Hydrogen bonding of water in 3-methylpyridine studied by O 1s X-ray emission and absorption spectroscopy.
PubMed:2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation.
PubMed:catena-Poly[[(3-methyl-pyridine)-copper(I)]-μ-cyanido-copper(I)-μ-cyanido].
PubMed:catena-Poly[[diaqua-bis-(3-methyl-pyridine-κN)cobalt(II)]-μ-sulfato-κO:O'].
PubMed:Bis(3-methyl-pyridine-κN)bis-(thio-cyanato-κN)zinc.
PubMed:2-Eth-oxy-6-[(3-methyl-pyridin-2-yl)-imino-meth-yl]phenol.
PubMed:Structural, magnetic, and gas adsorption study of a series of partially fluorinated metal-organic frameworks (HF-MOFs).
PubMed:Copper(II) complexes of 2-halo-3-methylpyridine: synthesis, structure, and magnetic behaviour of Cu(2-X-3-CH(3)py)2X'2 [X, X' = chlorine or bromine; py = pyridine].
PubMed:Synthesis, crystal structure, quantum chemical calculations, DNA interactions, and antimicrobial activity of [Ag(2-amino-3-methylpyridine)(2)]NO(3) and [Ag(pyridine-2-carboxaldoxime)NO(3)].
PubMed:Synthesis and characterisation of two novel proton transfer compounds and their inhibition studies on carbonic anhydrase isoenzymes.
PubMed:Poly[[diaqua-tris-(μ(2)-3-methyl-pyridine-2-carboxyl-ato)(3-methyl-pyridine-2-car-boxyl-ato)sodiumterbium(III)] ethanol monosolvate monohydrate].
PubMed:catena-Poly[sodium [[tris(3-methyl-pyridine-2-carboxylato)europate(III)]-μ-3-methylpyridine-2-carboxylato] trihydrate].
PubMed:Bis(2-amino-3-methyl-pyridine)-dichlorido-cobalt(II).
PubMed:Photocytotoxic trans-diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers.
PubMed:Di-mu-acesulfamato-kappa3N,O:O;kappa3O:N,O-bis[(acesulfamato-kappa2N,O)bis(3-methylpyridine)cadmium(II)].
PubMed:Multilamellar structures induced by hydrophilic and hydrophobic ions added to a binary mixture of D2O and 3-methylpyridine.
PubMed:Pseudo-cyclic face-to-face rigid structure caused by the intramolecular ion pair effect.
PubMed:Rhythmic oscillation and dynamic instability of micrometer-size phase separation under continuous photon flux by a focused laser.
PubMed:Reversible phase transition of colloids in a binary liquid solvent.
PubMed:Diaqua-sodium(I) perchlorate bis-[μ-2-(carboxyl-atomethyl-imino-meth-yl)phenolato]bis-[(3-methyl-pyridine)copper(II)].
PubMed:A simple synthesis route and characterisation of Co(3)Mo(3)C.
PubMed:Reactions of sulphate radicals with substituted pyridines: a structure-reactivity correlation analysis.
PubMed:Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids.
PubMed:Comparison of critical adsorption scaling functions obtained from neutron reflectometry and ellipsometry.
PubMed:Conjugate addition of 2- and 4-pyridylcuprates: an expeditious asymmetric synthesis of natural (-)-evoninic acid.
PubMed:[Separation and purification of 2-chloro-5-trichloromethylpyridine from products of photochemical chlorination of 3-methylpyridine using preparative liquid chromatography].
PubMed:Bis(acesulfamato-kappaO4)diaquabis(3-methylpyridine-kappaN)nickel(II).
PubMed:Dichloro(O-ethyl 3-methylpyridine-2-carboximidic acid-kappa2N,N')copper(II).
PubMed:Bis(acesulfamato-kappa2O4,N)bis(3-methylpyridine)copper(II).
PubMed:Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis.
PubMed:Methyl ethyl ketone+water+secondary butyl alcohol: a potential system for the exploration of a quadruple critical point.
PubMed:Synthesis, physicochemical and anticonvulsant properties of new N-(pyridine-2-yl) derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione. Part II.
PubMed:Relaxation dynamics of highly vibrationally excited picoline isomers (E(vib) = 38 300 cm(-1)) with CO2: the role of state density in impulsive collisions.
PubMed:A simple quantum statistical thermodynamics interpretation of an impressive phase diagram pressure shift upon (H/D) isotopic substitution in water + 3-methylpyridine.
PubMed:Critical behavior of the aqueous electrolytic system 3-methylpyridine+D2O+NaBr.
PubMed:(6,7-Dimethyl-2,3-di-2-pyridylquinoxaline)bis(3-methylpyridine)platinum(II) bis(hexafluorophosphate) acetone solvate 0.5-hydrate.
PubMed:Comparative chronic toxicity of pyridine, alpha-picoline, and beta-picoline to Lemna minor L. and Chlorella vulgaris B.
PubMed:NMR probing of structural peculiarities in ionic solutions close to critical point.
PubMed:Novel 2,2-bipyridine ligand for palladium-catalyzed regioselective carbonylation.
PubMed:Structure, reactivity and solution behaviour of [Re(ser)(7-MeG)(CO)(3)] and [Re(ser)(3-pic)(CO)(3)]: "nucleoside-mimicking" complexes based on the fac-[Re(CO)(3)](+) moiety.
PubMed:Dynamic activation of cystic fibrosis transmembrane conductance regulator by type 3 and type 4D phosphodiesterase inhibitors.
PubMed:Collective and self-diffusion coefficients in an ionic critical mixture: 3-methylpyridine+water+NaBr.
PubMed:Kinetics and mechanisms of the electron transfer reactions of oxo-centred carboxylate bridged complexes, [Fe3(mu3-O)(O2CR)6L3]ClO4, with verdazyl radicals in acetonitrile solution.
PubMed:The two-dimensional coordination polymer poly[[bis(3-methylpyridine)cadmium(II)]-tetra-mu-cyano-nickel(II)].
PubMed:Biarylcarboxybenzamide derivatives as potent vanilloid receptor (VR1) antagonistic ligands.
PubMed:Criticality in aqueous solutions of 3-methylpyridine and sodium bromide.
PubMed:Analyzing of segregation in mixtures of 3-methylpyridine and heavy water by dynamic neutron radiography.
PubMed:Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-[2-(3,4-Bisdifluromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor.
PubMed:Conversion of 2-deoxy-D-ribose into 2-amino-5-(2-deoxy-beta-D-ribofuranosyl)pyridine, 2'-deoxypseudouridine, and other C-(2'-deoxyribonucleosides).
PubMed:Pyridines in cigarette smoke inhibit hamster oviductal functioning in picomolar doses.
PubMed:Modified photoreactivity due to mixed crystal formation. II. Enhanced reactivity upon conformational mimicry and cavity enlargement.
PubMed:Novel morpholinone-based D-Phe-Pro-Arg mimics as potential thrombin inhibitors: design, synthesis, and X-ray crystal structure of an enzyme inhibitor complex.
PubMed:Modified photoreactivity due to mixed crystal formation. I. Three mixed crystals between isostructural cobaloxime complexes.
PubMed:Degradation of 3-methylpyridine and 3-ethylpyridine by Gordonia nitida LE31.
PubMed:Topological ferrimagnetic behavior of two new [Mn(L)2(N3)2]n chains with the new AF/AF/F alternating sequence (L = 3-methylpyridine or 3,4-dimethylpyridine).
PubMed:Experimental evidence for crossover to mean-field tricritical behavior in a concentrated salt solution
PubMed:Gordonia nitida sp. nov., a bacterium that degrades 3-ethylpyridine and 3-methylpyridine.
PubMed:Dimeric copper(II) trimethylsilylacetate adducts with pyridine, 2-methylpyridine, 3-methylpyridine and quinoline, and a polymeric copper(II) trimethylsilylacetate
PubMed:Dimeric copper(II) 3,3-dimethylbutyrate adducts with ethanol, 2-methylpyridine, 3-methylpyridine, 4-methylpyridine and 3,3-dimethylbutyric acid
PubMed:Surface active properties of simple cyclic and heterocyclic amines in water.
PubMed:Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice.
PubMed:Comutagenesis--V: rapid conversion of 2-hydroxyl-amino-3-methylpyridineto 2-amino-3-methylpyridine by a hepatic S9 preparation.
PubMed:Comutagenesis-IV in vitro metabolism of the comutagen 2-amino-3-methylpyridine: species differences and metabolic interaction with norharman.
PubMed:Comutagenesis-III. In vitro metabolism of 2-amino-3-methylpyridine: the effect of various potential inhibitors, activators and inducers.
PubMed:Comutagenesis-I: the in vitro metabolism of 2-amino-3-methylpyridine.
PubMed:Comutagenesis-II. Some Factors Influencing the In Vitro Metabolism of 2-Amino-3-Methylpyridine.
PubMed:Antisecretory and antiulcer effect of T-330, a novel reversible proton pump inhibitor, in rats.
PubMed:Analogues of methotrexate in rheumatoid arthritis. 1. Effects of 10-deazaaminopterin analogues on type II collagen-induced arthritis in mice.
PubMed:Reversible inhibition of rat gastric H+/K+-ATPase by T-330, 2-[2-dimethylaminobenzyl)sulfinyl]-1-(3-methylpyridine-2-yl)imidazole.
PubMed:Use of borinium ions as probes of steric effects in gas-phase ion-molecule complexes.
PubMed:The proton pump inhibitor, E3810, binds to the N-terminal half of the alpha-subunit of gastric H+,K(+)-ATPase.
PubMed:Effects of Maillard reaction products on mutagen formation in boiled pork juice.
PubMed:Determination of a new H(+)-K+ ATPase inhibitor (E3810) and its four metabolites in human plasma by high-performance liquid chromatography.
PubMed:[Inhibitory action of E3810 on H+,K(+)-ATPase and gastric acid secretion in vitro].
PubMed:Microbial metabolism of quinoline and related compounds. XVII. Degradation of 3-methylquinoline by Comamonas testosteroni 63.
PubMed:Structural investigations and modeling of cavities in clathrates.
PubMed:Inhibitions of acid secretion by E3810 and omeprazole, and their reversal by glutathione.
PubMed:The potency of substituted benzimidazoles such as E3810, omeprazole, Ro 18-5364 to inhibit gastric H+, K(+)-ATPase is correlatedwith the rate of acid-activation of the inhibitor.
PubMed:Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver.
PubMed:Neurophysiological consequences of acute exposure to methylpyridines.
PubMed:Shear-viscosity behavior near the double critical point of the mixture 3-methylpyridine, water, and heavy water.
PubMed:[The effect of new quaternary ammonium compounds on bacteria and fungi. 5: Synthesis of 3-methyl-n-alkylthiomethylpyridinium-, 1-methyl-3-n-alkylthiomethylimidazolium- and 1-ethyl-3-n-alkylthioimidazolinium chloride].
PubMed:Comutagenic effect of norharman with aminopyridine derivatives.
PubMed:The metabolic N-oxidation of 3-substituted pyridines in various animal species in vivo.
PubMed:The effect of various potential inhibitors, activators and inducers on the N-oxidation of 3-substituted pyridines in vitro.
PubMed:Some factors involved in the N-oxidation of 3-substituted pyridines by microsomal preparations in vitro.
PubMed:[Comparison of the processes of growth and transformation during 3-methylpyridine conversion by Nocardia cultures].
PubMed:[Mass-spectrometric study of the mechanism of microbial oxidation of 3-pyridinaldehyde].
PubMed:[Kinetic sorption of nicotinic acid by anionites].
PubMed:Stereochemistry of cobalt porphyrins. I. The structure and characterization of 2,3,7,8,12,13,17,18-octaethylporphinatobis(3-methylpyridine)cobalt(II).
PubMed:[Transformation of 3-methylpyridine to biologically active derivatives and its intracellular localization in rat liver].
PubMed:[The effect of 3-methylpyridine on the pyridine coenzyme and ubiquinone content in the tissues of normal and PP-avitaminotic rats].
PubMed:[Changes in the activity of liver NADase in rats after administration of nicotinic acid, 3-methylpyridine and nicotinamide in excess].
 
Notes:
None found
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