EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro,laevo-menthol
DL-menthol

Supplier Sponsors

Fragrance Demo Formulas
Name:5-methyl-2-propan-2-ylcyclohexan-1-ol
CAS Number: 89-78-1Picture of molecule3D/inchi
Other:15356-70-4
ECHA EINECS - REACH Pre-Reg:201-939-0
FDA UNII:YS08XHA860
Nikkaji Web:J2.129F
Beilstein Number:3194263
MDL:MFCD00001484
CoE Number:63
XlogP3-AA:3.00 (est)
Molecular Weight:156.26860000
Formula:C10 H20 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FR DOC # 2011-635 Menthol Report Subcommittee of the Tobacco Products Scientific Advisory Committee; Notice of Meeting Pages 2397 - 2398 View-petition PDF
JECFA Food Flavoring:427 menthol
FLAVIS Number:02.015 (Old)
DG SANTE Food Flavourings:02.015 menthol
FEMA Number:2665 menthol
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: MENTHOL
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
 
Physical Properties:
Appearance:colorless crystalline fused (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 34.00 to 36.00 °C. @ 760.00 mm Hg
Boiling Point: 212.00 to 216.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.032000 mm/Hg @ 25.00 °C. (est)
Flash Point: 200.00 °F. TCC ( 93.33 °C. )
logP (o/w): 3.400
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 paraffin oil
 water, 434.5 mg/L @ 25 °C (est)
 water, 456 mg/L @ 25 °C (exp)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: mentholic
Odor Strength:medium ,
recommend smelling in a 10.00 % solution or less
Substantivity:32 hour(s) at 100.00 %
peppermint cooling woody
Odor Description:at 10.00 % in dipropylene glycol. peppermint cool woody
Flavor Type: cooling
cooling mentholic minty
Taste Description: cooling mentholic minty
Odor and/or flavor descriptions from others (if found).
Symrise
Menthol rac.
Odor Description:minty-fresh
Taste Description:minty-cooling
Useful in: mint.
Blue Pacific Flavors
Menthol
Odor Description:peppermint cool woody
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Aromatic and Allied Chemicals
Liquid Menthol
Arora Aromatics
Natural Menthol Powder / Melted
Aurochemicals
MENTHOL CRYSTALS, Natural
Berjé
Menthol Racemic
Happening at Berje
Blue Pacific Flavors
Menthol
Odor: peppermint cool woody
BOC Sciences
For experimental / research use only.
DL-Menthol PURIFIED
EMD Millipore
For experimental / research use only.
DL-Menthol
Ernesto Ventós
MENTHOL RACEMIC, SYMRISE
Odor: MINTY, FRESH
Ernesto Ventós
MENTHOL-DL BASF
Odor: MINTY, FRESH
Flavor: MINTY, COOLING
Ernesto Ventós
MENTHOL, LIQUID
Fleurchem
menthol, racemic USP
Foodchem International
Menthol Crystal
Global Essence
Menthol Block
Liberty Natural Products
MENTHOL LIQUID INDIA
OQEMA
Menthol Crystals
Pangaea Sciences
Menthol USP
Penta International
DL-MENTHOL USP (RACEMIC) SYNTHETIC, Kosher
Prinova
Menthol
R C Treatt & Co Ltd
Menthol
Reincke & Fichtner
DL-Menthol
Santa Cruz Biotechnology
For experimental / research use only.
(±)-Menthol
Sigma-Aldrich
DL-Menthol, ≥95%, FCC, FG
Odor: minty; woody; camphoraceous
Certified Food Grade Products
Silverline Chemicals
Liquid Menthol
SRS Aromatics
MENTHOL CRYSTALS
Symrise
Menthol rac. PH
Symrise
Menthol rac.
Odor: minty-fresh
Flavor: minty-cooling
Useful in: mint.
Symrise
Menthol RC
Odor: minty-fresh
Flavor: minty-cooling
Useful in: mint.
TCI AMERICA
For experimental / research use only.
(±)-Menthol >98.0%(GC)
The Good Scents Company
dextro,laevo-menthol
Odor: peppermint cool woody
The Lermond Company
Menthol, Racemic
Vigon International
Menthol Crystals Natural FCC
Vigon International
Menthol Liquid
Vigon International
Menthol Racemic
Xi'an Herbphar
Menthol crystal
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 37/38 - Irritating to respiratory system and skin.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
GHS Label elements, including precautionary statements
 
Pictogramcorrosion.jpgexclamation-mark.jpg
 
Signal word Danger
Hazard statement(s)
H315 - Causes skin irritation
H318 - Causes serious eye damage
H335 - May cause respiratory irritation
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P271 - Use only outdoors or in a well-ventilated area.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310 - Immediately call a POISON CENTER or doctor/physician.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
gavage-mouse LD50 [sex: M] 2652 mg/kg
(Food & Drug Research LaboratoriesInc., 1975a)

gavage-mouse LD50 [sex: M] 4384 mg/kg
(Food & Drug Research Laboratories Inc, 1975a)

gavage-mouse LD50 3100 mg/kg
(Wokes, 1932)

gavage-rat LD50 [sex: M,F] 3180 mg/kg
(Jenner et al., 1964)

intravenous-cat LDLo 37 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 63, Pg. 43, 1939.

oral-cat LDLo 1500 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

intraperitoneal-mouse LDLo 1800 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 63, Pg. 43, 1939.

intramuscular-rat LD50 10000 mg/kg
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 222, Pg. 244, 1954.

oral-rat LD50 3180 mg/kg
BEHAVIORAL: ATAXIA
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

intraperitoneal-rat LDLo 1500 mg/kg
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: SLEEP BEHAVIORAL: MUSCLE WEAKNESS
Annales Pharmaceutiques Francaises. Vol. 10, Pg. 481, 1952.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents
maximum skin levels for fine fragrances:
  0.5200 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2004)
Recommendation for dextro,laevo-menthol usage levels up to:
  8.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics:
  0.2900 %
Dermal Systemic Exposure in Cosmetic Products:
 0.0074 mg/kg/day (IFRA, 2004)
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 16000.00 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -130.00000
beverages(nonalcoholic): -35.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -1100.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -68.00000
fruit ices: -68.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -400.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 18 (FGE.18): Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical group 6
View page or View pdf

Flavouring Group Evaluation 51, (FGE.51)[1] - Consideration of alicyclic ketones and secondary alcohols and related esters evaluated by JECFA (59th meeting) and structurally related to alicyclic ketones, secondary alcohols and related esters evaluated by EFSA in FGE.09 (2004) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 14, Revision 1 (FGE.14Rev1): Phenethyl alcohol, aldehyde, acetals, carboxylic acid and related esters from chemical group 15 and 22 [1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 18, Revision 1 (FGE. 18 Rev1)[1] : Aliphatic, alicyclic and aromatic saturated and unsaturated tertiary alcohols, aromatic tertiary alcohols and their esters from chemical groups 6 and 8
View page or View pdf

Flavouring Group Evaluation 43: Thujyl alcohol from chemical group 8
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 90 (FGE.90): Consideration of Aliphatic, acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances evaluated by JECFA (68th meeting)FGE.18Rev1 (2009)
View page or View pdf

Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

Safety and efficacy of secondary alicyclic saturated and unsaturated alcohols, ketones, ketals and esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols from chemical group 8 when used as flavourings for all animal species
View page or View pdf

EPI System: View
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):89-78-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1254
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
5-methyl-2-propan-2-ylcyclohexan-1-ol
Chemidplus:0000089781
EPA/NOAA CAMEO:hazardous materials
RTECS:OT0350000 for cas# 89-78-1
 
References:
Leffingwell:Chirality or Article
 5-methyl-2-propan-2-ylcyclohexan-1-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:89-78-1
Pubchem (cid):1254
Pubchem (sid):134972992
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D04849
HMDB (The Human Metabolome Database):HMDB35765
FooDB:FDB015462
Export Tariff Code:2906.11.0000
Haz-Map:View
Household Products:Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•some synthetic menthols are not chemical individuals but...mixtures of various isomers...these are designated...l-menthol, dl-menthol, l-isomenthol, d-isomenthol, dl-isomenthol, l-neomenthol, d-neomenthol, l-neoisomenthol, d-neoisomenthol and dl-neoisomenthol. •when mixed with about equal wt of camphor, chloral hydrate, phenol, or thymol, menthol forms "eutectic" mixt liquifying @ room temp. •menthol, usp drug marketed under generic name. •grades: technical; usp; fcc •synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%. synthetic menthol is also commercially available as the racemic mixture •present in cigarettes and pipe tobacco (0.1-0.45%) shaving creams, pre- and aftershave lotions (0.2-0.3%); toothpastes (0.5%); mouthwashes (1-2%); chewing gums (0.5%); cough drops (0.1%); refreshing towels (1%); rubbing alcohol (1-1.2%); and shampoos (2-0.5%) •mentholatum deep heating rub contains 5.9% menthol; mentholatum ointment, 1.35%; mentholatum deep heating lotion, 6%
 
Potential Blenders and core components note
For Odor
anise
anise seed oil colombia
FL/FR
anisic
dihydroanethol
FL/FR
balsamic
amyris wood oil
FL/FR
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
iso
bornyl acetate
FL/FR
clover nitrile
FR
dextro-
fenchone
FL/FR
camphoreous
camphor tree bark oil
FL/FR
beta-homo
cyclocitral
FL/FR
fatty
decanol
FL/FR
floral
iso
amyl salicylate
FL/FR
bois de rose oil brazil
FL/FR
cyclohexyl ethyl alcohol
FL/FR
geranium oil bourbon
FL/FR
heliotropyl diethyl acetal
FR
alpha-
hexyl cinnamaldehyde
FL/FR
ho leaf oil
FR
hyacinth ether
FR
laevo-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
methyl dihydrojasmonate
FL/FR
nerol
FL/FR
ocean propanal
FL/FR
fruity
menthyl isovalerate
FL/FR
herbal
1,4-
cineole
FL/FR
eucalyptus globulus oil
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
abrialis
lavandin oil
FL/FR
lavender absolute bulgaria
FL/FR
spike
lavender oil
FL/FR
linalyl acetate
FL/FR
nopyl acetate
FR
rosemary oil spain
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil china
FL/FR
cornmint oil india
FL/FR
cornmint oil terpeneless
FL/FR
dextro-neo
menthol
FL/FR
(±)-
menthol
FL/FR
laevo-
menthol
FL/FR
dextro,laevo-neo
menthol
FL/FR
neoiso
menthol
FL/FR
(±)-iso
menthone
FL/FR
(+)-
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
menthyl acetate
FL/FR
menthyl acetate racemic
FL/FR
peppermint cyclohexanone
FL/FR
dextro-
piperitone
FL/FR
iso
pulegyl acetate
FL/FR
minty
laevo-
carvone
FL/FR
cornmint oil japan
FL/FR
cornmint oil terpenes
FR
dextro-
dihydrocarvone
FL/FR
mentha piperita extract
FL/FR
mentha piperita flower/leaf/stem extract
FL/FR
mentha piperita flower/leaf/stem water
FR
mentha piperita herb extract america
FR
mentha piperita leaf water
FR
mentha piperita tincture
FL/FR
homo
menthol
FL/FR
(-)-
menthone
FL/FR
(±)-
menthone
FL/FR
laevo-
menthyl lactate
FL/FR
2-
methyl cyclohexanone
FL/FR
methyl salicylate
FL/FR
pennyroyal oil
FL/FR
peppermint absolute
FL/FR
peppermint distillates
FL/FR
peppermint fragrance
FR
peppermint leaf
CS
peppermint oil
FL/FR
peppermint oil america
FL/FR
peppermint oil brazil
FL/FR
peppermint oil china
FL/FR
peppermint oil CO2 extract
FL/FR
peppermint oil dementholized
FL/FR
peppermint oil england
FL/FR
peppermint oil france
FL/FR
peppermint oil hungary
FL/FR
peppermint oil idaho
FL/FR
peppermint oil india
FL/FR
peppermint oil mongolia
FL/FR
peppermint oil montana
FL/FR
peppermint oil morocco
FL/FR
peppermint oil russia
FL/FR
peppermint oil special fractions
FL/FR
peppermint oil tasmania
FL/FR
peppermint oil terpeneless
FL/FR
peppermint oil terpenes
FR
peppermint oil willamette
FL/FR
peppermint oil yakima
FL/FR
peppermint water
FL/FR
laevo-
piperitone
FL/FR
(-)-iso
pulegol
FL/FR
iso
pulegol
FL/FR
iso
pulegone
FL/FR
(R)-(+)-
pulegone
FR
spearmint oil america
FL/FR
wintergreen oil
FL/FR
WS-23
FL/FR
phenolic
methyl benzoate
FL/FR
powdery
para-
anisyl alcohol
FL/FR
spicy
elettaria cardamomum seed oil
FL/FR
pepper tree berry oil
FL/FR
pimenta acris leaf oil
FL/FR
terpenic
alpha-
terpineol
FL/FR
waxy
decyl acetate
FL/FR
woody
(Z)-
woody amylene
FR
For Flavor
No flavor group found for these
(±)-N,N-
dimethyl menthyl succinamide
FL
neoiso
menthol
FL/FR
dextro,laevo-neo
menthol
FL/FR
3-laevo-
menthoxy-2-methyl propane-1,2-diol
FL
menthyl acetate racemic
FL/FR
2-
methyl cyclohexanone
FL/FR
iso
pulegone
FL/FR
menthyl methyl lactate
FL
anise
anise
anise seed oil colombia
FL/FR
balsamic
benzyl salicylate
FL/FR
laevo-
bornyl acetate
FL/FR
camphoreous
camphor tree bark oil
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
citrus
linalool
FL/FR
laevo-
linalool
FL/FR
nerol
FL/FR
alpha-
terpineol
FL/FR
cooling
1,4-
cineole
FL/FR
beta-homo
cyclocitral
FL/FR
dextro-
fenchone
FL/FR
spike
lavender oil
FL/FR
laevo-
menthol
FL/FR
iso
menthol
FL
menthyl acetate
FL/FR
laevo-
menthyl lactate
FL/FR
peppermint oil america
FL/FR
floral
bois de rose oil brazil
FL/FR
geranium oil bourbon
FL/FR
linalyl acetate
FL/FR
methyl dihydrojasmonate
FL/FR
ocean propanal
FL/FR
fruity
para-
anisyl alcohol
FL/FR
menthyl isovalerate
FL/FR
green
iso
amyl salicylate
FL/FR
cyclohexyl ethyl alcohol
FL/FR
dextro-
dihydrocarvone
FL/FR
linalool oxide
FL/FR
iso
phorone
FL
herbal
dihydroanethol
FL/FR
eucalyptus globulus oil
FL/FR
abrialis
lavandin oil
FL/FR
lavender absolute bulgaria
FL/FR
rosemary oil spain
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro-neo
menthol
FL/FR
(+)-
menthone
FL/FR
peppermint cyclohexanone
FL/FR
minty
laevo-
carvone
FL/FR
cherry menthol flavor
FL
cornmint oil china
FL/FR
cornmint oil india
FL/FR
cornmint oil japan
FL/FR
mentha piperita extract
FL/FR
mentha piperita flower/leaf/stem extract
FL/FR
mentha piperita tincture
FL/FR
homo
menthol
FL/FR
(-)-
menthone
FL/FR
(±)-iso
menthone
FL/FR
(±)-
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
methyl salicylate
FL/FR
pennyroyal oil
FL/FR
peppermint absolute
FL/FR
peppermint distillates
FL/FR
peppermint flavor
FL
peppermint oil
FL/FR
peppermint oil brazil
FL/FR
peppermint oil china
FL/FR
peppermint oil CO2 extract
FL/FR
peppermint oil dementholized
FL/FR
peppermint oil england
FL/FR
peppermint oil france
FL/FR
peppermint oil hungary
FL/FR
peppermint oil idaho
FL/FR
peppermint oil india
FL/FR
peppermint oil mongolia
FL/FR
peppermint oil montana
FL/FR
peppermint oil morocco
FL/FR
peppermint oil russia
FL/FR
peppermint oil special fractions
FL/FR
peppermint oil tasmania
FL/FR
peppermint oil terpeneless
FL/FR
peppermint oil willamette
FL/FR
peppermint oil yakima
FL/FR
peppermint water
FL/FR
laevo-
piperitone
FL/FR
dextro-
piperitone
FL/FR
(-)-iso
pulegol
FL/FR
iso
pulegol
FL/FR
spearmint oil america
FL/FR
wintergreen oil
FL/FR
WS-23
FL/FR
phenolic
methyl benzoate
FL/FR
spicy
elettaria cardamomum seed oil
FL/FR
pepper tree berry oil
FL/FR
pimenta acris leaf oil
FL/FR
terpenic
para-
menthatriene
FL
waxy
decanol
FL/FR
decyl acetate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
woody
amyris wood oil
FL/FR
iso
bornyl acetate
FL/FR
iso
pulegyl acetate
FL/FR
 
Potential Uses:
 betel
FRcitrus
FLcream ice cream
FRherbal
FRmint
FL/FRpennyroyal
FRpeppermint
FRrose
FRspearmint
FRtobacco
FRwintergreen
 
Occurrence (nature, food, other):note
 peppermint
Search Trop Picture
 
Synonyms:
 cyclohexanol, 5-methyl-2-(1-methylethyl)-
dextro,laevo-hexahydrothymol
DL-hexahydrothymol
dextro,laevo-menthacamphor
DL-menthacamphor
p-menthan-3-ol
para-menthan-3-ol
p-menthane-3-ol
para-menthane-3-ol
(±)-menthol
(±)-(1R*,3R*,4S*)-menthol
DL-menthol
 menthol crystals FCC natural
 menthol crystals natural
 menthol Liquid
 menthol rac.
 menthol rac. PH
 menthol racemic
 menthol RC
dextro,laevo-menthol synthetic USP/FCC
 menthol USP
DL-menthol USP (racemic) synthetic
 menthol, racemic USP
(1alpha,2beta,5alpha)-5-methyl-2-(1-methyl ethyl) cyclohexanol
(1R,2S,5R)-rel-5-methyl-2-(1-methyl ethyl) cyclohexanol
(1alpha,2beta,5alpha)-5-methyl-2-(1-methylethyl)cyclohexanol
(1R,2S,5R)-rel-5-methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
dextro,laevo-peppermint camphor
DL-peppermint camphor
4-isopropyl-1-methyl cyclohexan-3-ol
4-isopropyl-1-methylcyclohexan-3-ol
(±)-2-isopropyl-5-methylcyclohexanol
 tra-kill tracheal mite killer
 

Articles:

Info:Menthol
PubMed:Terpenes increase the partitioning and molecular dynamics of an amphipathic spin label in stratum corneum membranes.
PubMed:Investigation of factors affecting the adsorption of functional molecules onto gel silicas. 1. Flow microcalorimetry and infrared spectroscopy.
PubMed:Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay).
PubMed:Factors affecting the resolution of dl-menthol by immobilized lipase-catalyzed esterification in organic solvent.
PubMed:Comparison of acid anhydrides with carboxylic acids in enantioselective enzymatic esterification of racemic menthol.
PubMed:Bioassay of dl-menthol for possible carcinogenicity.
PubMed:[Synthesis of DL-menthol].
PubMed:[On the assay of DL-menthol for contamination by DL-neomenthol. 2. Report on the menthol monography in a new German pharmacopoeia].
PubMed:Studies in detoxication: The use of the glucuronic acid detoxication mechanism of the rabbit for the resolution of dl-menthol.
PubMed:Studies in detoxication. II. (a) The conjugation of isomeric 3-menthanols with glucuronic acid and the asymmetric conjugation of dl-menthol and dl-isomenthol in the rabbit. (b) d-isoMenthylglucuronide, a new conjugated glucuronic acid.
 
Notes:
Found in many essential oils Menthol is an organic compound made synthetically or obtained from peppermint or other mint oils. Natural menthol exists as one pure stereoisomer, nearly always the (1R,2S,5R) form ((-)-menthol). There are 8 possible stereoisomers. (Wikipedia)
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