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laevo-menthyl lactate
L-menthyl lactate

Sponsors

Name:[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2-hydroxypropanoate
CAS Number: 59259-38-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:261-678-3
FDA UNII:XFS8QYW6WY
Nikkaji Web:J1.533.921G
MDL:MFCD00209517
XlogP3-AA:3.30 (est)
Molecular Weight:228.33188000
Formula:C13 H24 O3
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor and fragrance agents, active cooling ingredient
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:433 L-menthyl lactate
FLAVIS Number:09.551 (Old)
DG SANTE Food Flavourings:09.551 L-menthyl lactate
FEMA Number:3748 L-menthyl lactate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: L-MENTHYL LACTATE
 
Physical Properties:
Appearance:colorless white crystalline solid (est)
Assay: 97.00 to 100.00 sum of isomers
Food Chemicals Codex Listed: No
Melting Point: 42.00 to 47.00 °C. @ 760.00 mm Hg
Boiling Point: 142.00 °C. @ 5.00 mm Hg
Boiling Point: 302.00 to 303.00 °C. @ 760.00 mm Hg
Congealing Point:40.00 °C.
Acid Value: 2.00 max. KOH/g
Vapor Pressure:0.000085 mm/Hg @ 25.00 °C. (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 3.358 (est)
Soluble in:
 alcohol
 oils
 water, very slightly
 water, 141.4 mg/L @ 25 °C (est)
Insoluble in:
 water
Similar Items:note
amyl lactate
isoamyl lactate
benzyl lactate
butyl butyryl lactate
butyl lactate
isobutyl lactate
sec-butyl lactate
butyl laevo-lactate
cetyl lactate
dodecyl lactate
ethyl acetyl lactate
ethyl butyryl lactate
ethyl lactate
ethyl phenyl lactate
(Z)-3-hexen-1-yl lactate
hexyl lactate
menthyl methyl lactate
methyl dextro-lactate
methyl laevo-lactate
phenethyl lactate
propyl lactate
vanillyl lactate
 
Organoleptic Properties:
Odor Type: minty
Odor Strength:low
cooling
Odor Description:at 100.00 %. mild cooling
Odor Description:Little or no apparent odor
Mosciano, Gerard P&F 23, No. 2, 43, (1998)
Flavor Type: cooling
cooling mentholic
Taste Description: at 25.00 ppm. Latent but lingering cooling menthol
Mosciano, Gerard P&F 23, No. 2, 43, (1998)
Odor and/or flavor descriptions from others (if found).
Symrise
Symcool® nat.
Odor Description:faintly minty, easily masked by perfume oils
Taste Description:fresh, mild cooling, sweet menthol taste
Useful in: mint, fruity yellow.
Symrise
Frescolat® ML
Odor Description:characteristic
Instant yet mild cooling sensation.
Symrise
Frescolat® ML cryst.
Odor Description:characteristic
Non-irritating, menthol free.
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
refreshing agents
 
Suppliers:
Advanced Biotech
COOLADA-ML SYNTHETIC
90% min.
Advanced Biotech
MENTHYL LACTATE NATURAL
90.0% min.
Anhui Haibei
Menthyl Lactate
Apple Flavor & Fragrance
l-Menthyl lactate
Aurochemicals
L-MENTHYL LACTATE, Natural
BOC Sciences
For experimental / research use only.
L-Menthyl Lactate
Charkit Chemical
FRIGYDIL
Citrus and Allied Essences
laevo-Menthyl Lactate (natural)
Market Report
Citrus and Allied Essences
laevo-Menthyl Lactate
ECSA Chemicals
Menthyl Lactate
Company Profile
Indukern F&F
MENTHYL LACTATE
Odor: SMOOTH, MENTHOLATED, REFRESHING, SWEET
Inoue Perfumery
L-MENTHYL LACTATE
Kun Shan P&A
Menthyl Lactate
M&U International
NAT. L-MENTHYL LACTATE
Moellhausen
SYMCOOL NAT.
Odor: fresh, minty, somewhat burnt sugar
Flavor: , minty, somewhat burnt sugar; latent but lingering cooling menthol
Natural Advantage
Menthyl Lactate Nat
Nectar Lifesciences
Menthyl Lactate
O'Laughlin Industries
ARCTIC ML CRYSTAL
O'Laughlin Industries
ARCTIC ML
OQEMA
Menthyl Lactate Liquid
OQEMA
Menthyl Lactate Powder
Pearlchem Corporation
Menthyl Lactate
Penta International
L-MENTHYL LACTATE CRYSTALS, Kosher
Penta International
L-MENTHYL LACTATE NATURAL, Kosher
Penta International
L-MENTHYL LACTATE, Kosher
Renessenz (Symris)
L-Menthyl Lactate 98%
Odor: Menthyl lactate is a white solid or fused substance with virtually no taste and faint minty odor
Use: Can be used in confectionery and other applications to provide a lasting cooling effect, alone or with other cooling agents.
Riverside Aromatics
MENTHYL LACTATE NATURAL
Shanghai Vigen Fine Chemical
l-Menthyl Lactate
Sigma-Aldrich
L-Menthyl lactate, ≥97%, FG
Certified Food Grade Products
Symrise
Frescolat® ML cryst.
Odor: characteristic
Use: Non-irritating, menthol free.
Symrise
Frescolat® ML nat.
Odor: characteristic
Use: Natural (Ecocert approved)
Symrise
Frescolat® ML
Odor: characteristic
Use: Instant yet mild cooling sensation.
Symrise
Frescolat® Plus
Odor: characteristic
Use: Strong, long lasting cooling effect.
Symrise
Symcool® nat.
Flavor: fresh, mild cooling, sweet menthol taste
Useful in: mint, fruity yellow.
Synerzine
L-Menthyl Lactate
Synerzine
L-Menthyl Lactate
Vigon International
Frescolat ML (Menthyl Lactate)
Odor: Cooling,Minty,Medicinal
Vigon International
Frescolat ML Crystals (Menthyl Lactate)
Vigon International
Frescolat ML Natural (Menthyl Lactate Natural)
Vigon International
Frescolat Plus (Menthol and Menthyl Lactate)
Vigon International
Symcool Natural (Frescolat ML Natural)
Wanxiang International
L-Menthyl Lactate
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 7257 mg/kg
Non-irritating, menthol free.

Dermal Toxicity:
skin-rabbit LD50 > 10000 mg/kg
Non-irritating, menthol free.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavor and fragrance agents, active cooling ingredient
Recommendation for laevo-menthyl lactate usage levels up to:
  8.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 14. Update in publication number(s): 18
 average usual ppmaverage maximum ppm
baked goods: 60.00000250.00000
beverages(nonalcoholic): 30.00000120.00000
beverages(alcoholic): 100.00000400.00000
breakfast cereal: 15.0000060.00000
cheese: 15.0000060.00000
chewing gum: 1000.000002000.00000
condiments / relishes: 100.00000400.00000
confectionery froastings: 500.000002000.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: 30.00000120.00000
fruit ices: 100.00000400.00000
gelatins / puddings: 200.00000800.00000
granulated sugar: --
gravies: 25.00000100.00000
hard candy: 1000.000002000.00000
imitation dairy: 15.0000060.00000
instant coffee / tea: 100.00000400.00000
jams / jellies: --
meat products: --
milk products: 200.00000800.00000
nut products: --
other grains: --
poultry: --
processed fruits: 100.00000400.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 25.00000100.00000
soft candy: 500.000002000.00000
soups: 25.00000100.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):59259-38-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :62151
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2-hydroxypropanoate
Chemidplus:0059259380
 
References:
Leffingwell:Chirality or Article
 [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2-hydroxypropanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:59259-38-0
Pubchem (cid):62151
Pubchem (sid):135020134
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):HMDB37212
Export Tariff Code:2918.11.0000
Household Products:Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
corn oil
CS
laevo-mono
menthyl glutarate
FL/FR
camphoreous
camphoreous
thujyl alcohol
FL/FR
verbenone
FL/FR
herbal
1,4-
cineole
FL/FR
spike
lavender oil
FL/FR
sabinene hydrate
FL/FR
medicinal
meta-
dimethyl hydroquinone
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil china
FL/FR
cornmint oil india
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro,laevo-
menthol
FL/FR
dextro-neo
menthol
FL/FR
laevo-
menthol
FL/FR
(±)-iso
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
menthyl acetate
FL/FR
menthyl acetate racemic
FL/FR
iso
pulegyl acetate
FL/FR
minty
cornmint oil japan
FL/FR
cornmint oil terpenes
FR
dextro-
dihydrocarvone
FL/FR
mentha arvensis flower/leaf/stem extract
FL/FR
mentha arvensis flower/leaf/stem water
FL/FR
mentha arvensis herb extract
FR
homo
menthol
FL/FR
(±)-
menthone
FL/FR
(-)-
menthone
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint oil america
FL/FR
peppermint oil idaho
FL/FR
iso
propyl tiglate
FL/FR
iso
pulegol
FL/FR
(-)-iso
pulegol
FL/FR
musty
3-
acetyl-2,5-dimethyl furan
FL/FR
nutty
2-
acetyl-3-ethyl pyrazine
FL/FR
3,5-
cocoa pyrazine
FL/FR
filbert pyrazine
FL/FR
popcorn
2-
acetyl pyridine
FL/FR
sulfurous
dimethyl sulfide
FL/FR
For Flavor
No flavor group found for these
mentha arvensis flower/leaf/stem extract
FL/FR
mentha arvensis flower/leaf/stem water
FL/FR
menthyl acetate racemic
FL/FR
laevo-mono
menthyl glutarate
FL/FR
menthyl propylene glycol carbonate
FL
verbenone
FL/FR
thujyl alcohol
FL/FR
chemical
chemical
meta-
dimethyl hydroquinone
FL/FR
cooling
1,4-
cineole
FL/FR
spike
lavender oil
FL/FR
laevo-
menthol
FL/FR
iso
menthol
FL
dextro,laevo-
menthol
FL/FR
menthyl acetate
FL/FR
peppermint oil america
FL/FR
sabinene hydrate
FL/FR
WS-5
FL
corn
2-
acetyl pyridine
FL/FR
yellow
corn flavor
FL
sweet
corn flavor
FL
white
corn flavor
FL
corn flavor
FL
fatty
dimethyl sulfoxide
FL
green
dextro-
dihydrocarvone
FL/FR
iso
propyl tiglate
FL/FR
malty
yeast thiazoline
FL
mentholic
cornmint oil
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro-neo
menthol
FL/FR
minty
cornmint oil china
FL/FR
cornmint oil india
FL/FR
cornmint oil japan
FL/FR
homo
menthol
FL/FR
(±)-iso
menthone
FL/FR
(±)-
menthone
FL/FR
(-)-
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint oil idaho
FL/FR
(-)-iso
pulegol
FL/FR
iso
pulegol
FL/FR
nutty
3-
acetyl-2,5-dimethyl furan
FL/FR
2-
acetyl-3-ethyl pyrazine
FL/FR
3,5-
cocoa pyrazine
FL/FR
filbert pyrazine
FL/FR
sour
corn apple cider vinegar flavor
FL
sulfurous
dimethyl sulfide
FL/FR
ethyl methyl sulfide
FL
woody
iso
pulegyl acetate
FL/FR
 
Potential Uses:
 fruit
FRmint
 
Occurrence (nature, food, other):note
 cornmint
Search Trop Picture
 
Synonyms:
 arctic ML
 arctic ML crystal
 coolada-ML
 coolada-ML synthetic (Advanced Biotech)
 frescolat ML (Symrise)
 frescolat ML cryst. (Symrise)
 frescolat ML crystals (Symrise)
 frescolat ML nat. (Symrise)
 frescolat ML natural (Symrise)
 frescolat plus (Symrise)
2-hydroxypropanoic acid 5-methyl-2-(1-methyl ethyl) cyclohexyl ester
 menthan-3-yl lactate, (-)-p-
(-)-menthyl lactate
L-menthyl lactate
laevo-menthyl lactate (natural)
L-menthyl lactate crystals
 menthyl lactate natural
 menthyl lactate, L-
5-methyl-2-(1-methyl ethyl) cyclohexyl alpha-hydroxypropanoate
(1R-(1alpha(R*), 2beta,5alpha))-5-methyl-2-(1-methyl ethyl) cyclohexyl lactate
L-5-methyl-2-(laevo-methyl ethyl) cyclohexyl lactate
laevo-5-methyl-2-(laevo-methyl ethyl) cyclohexyl lactate
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 2-hydroxypropanoate
[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2-hydroxypropanoate
 propanoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-hydroxypropanoate
 symcool (Symrise)
 symcool natural (Symrise)
 
 
Notes:
None found
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