EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

1,3-dihydroxyacetone (dimer)
(2S,5R)-2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol

Sponsors

Name:(2S,5R)-2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol
CAS Number: 62147-49-3Picture of molecule3D/inchi
Nikkaji Web:J1.220.341A
Beilstein Number:0112910
MDL:MFCD00051019
XlogP3-AA:-3.10 (est)
Molecular Weight:180.15684000
Formula:C6 H12 O6
NMR Predictor:Predict (works with chrome or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1716 1,3-dihydroxyacetone dimer
FEMA Number:4033 1,3-dihydroxyacetone dimer
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: DIHYDROXYACETONE (DIMER)
 
Physical Properties:
Appearance:white to tan powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 75.00 to 80.00 °C. @ 760.00 mm Hg
Boiling Point: 448.00 to 449.00 °C. @ 760.00 mm Hg
Flash Point: 436.00 °F. TCC ( 224.44 °C. )
logP (o/w): -0.951 (est)
Soluble in:
 alcohol
 water
 water, 9.582e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Type: cooling
Odor Strength:medium
sweet cooling
Odor Description:at 100.00 %. sweet cooling
Flavor Type: cooling
">cooling
Taste Description: cooling
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Axsyn
For experimental / research use only.
1,4-Dioxane-2,5-dimethanol,2,5-dihydroxy-, (2R,5S)-rel-
BOC Sciences
For experimental / research use only.
2,5-Dihydroxy-1,4-dioxane-2,5-dimethanol >96.0%(T)
Penta International
1,3-DIHYDROXYACETONE DIMER
Santa Cruz Biotechnology
For experimental / research use only.
1,3-Dihydroxyacetone (dimer)
TCI AMERICA
For experimental / research use only.
1,3-Dihydroxyacetone (dimer) >96.0%(T)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 60000 mg/kg
Laborit (1977)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for 1,3-dihydroxyacetone (dimer) usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 21
 average usual ppmaverage maximum ppm
baked goods: 50.00000200.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: 120.00000600.00000
cheese: --
chewing gum: --
condiments / relishes: 300.000001200.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 80.00000320.00000
fruit ices: --
gelatins / puddings: 40.00000240.00000
granulated sugar: --
gravies: 80.00000240.00000
hard candy: 300.000001200.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 20.00000200.00000
milk products: 40.00000200.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: 80.00000240.00000
reconstituted vegetables: --
seasonings / flavors: 400.000002400.00000
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2723627
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S,5R)-2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol
Chemidplus:0062147493
 
References:
 (2S,5R)-2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):2723627
Pubchem (sid):135348750
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
Metabolomics Database:Search
HMDB (The Human Metabolome Database):HMDB32222
FooDB:FDB009293
Export Tariff Code:2932.99.9090
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
balsamic
iso
bornyl formate
FL/FR
dextro-
fenchone
FL/FR
camphoreous
beta-homo
cyclocitral
FL/FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
citrus
ocimene quintoxide
FL/FR
earthy
(-)-alpha-
fenchol
FL/FR
ethereal
cyclohexyl formate
FL/FR
floral
iso
butyl salicylate
FL/FR
dihydrocarvyl acetate
FL/FR
fruity
cyclohexyl acetate
FL/FR
menthyl isovalerate
FL/FR
pineapple pentenoate
FL/FR
tropical trithiane
FL/FR
vanilla carboxylate
FL/FR
green
manzanate (Givaudan)
FL/FR
3,5,5-
trimethyl hexanol
FL/FR
herbal
1,8-
cineole
FL/FR
1,4-
cineole
FL/FR
dehydroxylinalool oxide
FL/FR
geranic oxide
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
hyssop oil
FL/FR
jambu oleoresin
FL/FR
spike
lavender oil
FL/FR
myrtenol
FL/FR
sabinene hydrate
FL/FR
theaspirane
FL/FR
medicinal
meta-
dimethyl hydroquinone
FL/FR
mentholic
cornmint oil china
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro-neo
menthol
FL/FR
dextro,laevo-
menthol
FL/FR
laevo-
menthol
FL/FR
(±)-iso
menthone
FL/FR
menthyl acetate
FL/FR
laevo-
menthyl acetate
FL/FR
menthyl acetate racemic
FL/FR
peppermint cyclohexanone
FL/FR
minty
betula lenta bark oil america
FL/FR
cornmint oil japan
FL/FR
homo
menthol
FL/FR
(±)-
menthone
FL/FR
(-)-
menthone
FL/FR
homo
menthyl acetate
FL/FR
laevo-
menthyl lactate
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint oil america
FL/FR
peppermint oil idaho
FL/FR
(-)-iso
pulegol
FL/FR
iso
pulegol
FL/FR
spearmint oil america
FL/FR
WS-23
FL/FR
naphthyl
para-
methyl anisole
FL/FR
odorless
dextro,laevo-
menthone glycerine acetal
FL/FR
spicy
iso
butyl angelate
FL/FR
4-
carvomenthenol
FL/FR
myrtenal
FL/FR
sulfurous
mango thiol
FL/FR
woody
camphene
FL/FR
(+)-
camphene
FL/FR
For Flavor
No flavor group found for these
(+)-
camphene
FL/FR
(±)-N,N-
dimethyl menthyl succinamide
FL
3-laevo-
menthoxy-2-methyl propane-1,2-diol
FL
menthyl acetate racemic
FL/FR
camphoreous
camphoreous
camphene
FL/FR
(-)-alpha-
fenchol
FL/FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
geranic oxide
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
chemical
meta-
dimethyl hydroquinone
FL/FR
cooling
(2S,5R)-N-[4-(2-
amino-2-oxoethyl)phenyl]-5-methyl-2-(propan-2-yl)cyclohexanecarboxamide
FL
iso
butyl salicylate
FL/FR
4-
carvomenthenol
FL/FR
1,4-
cineole
FL/FR
beta-homo
cyclocitral
FL/FR
dextro-
fenchone
FL/FR
1-(2-
hydroxy-4-methyl cyclohexyl) ethanone
FL
jambu oleoresin
FL/FR
spike
lavender oil
FL/FR
manzanate (Givaudan)
FL/FR
laevo-
menthol
FL/FR
iso
menthol
FL
dextro,laevo-
menthol
FL/FR
laevo-
menthone 1,2-glycerol ketal
FL
dextro,laevo-
menthone glycerine acetal
FL/FR
homo
menthyl acetate
FL/FR
menthyl acetate
FL/FR
laevo-
menthyl lactate
FL/FR
mono
menthyl succinate
FL
2-(4-
methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide
FL
peppermint oil america
FL/FR
N-(2-(
pyridin-2-yl)ethyl)-3-para-menthane carboxamide
FL
sabinene hydrate
FL/FR
theaspirane
FL/FR
WS-12
FL
WS-3
FL
WS-5
FL
earthy
panax quinquefolius root extract
FL
floral
dihydrocarvyl acetate
FL/FR
fruity
menthyl isovalerate
FL/FR
pineapple pentenoate
FL/FR
tropical trithiane
FL/FR
vanilla carboxylate
FL/FR
green
iso
butyl angelate
FL/FR
cyclohexyl formate
FL/FR
ocimene quintoxide
FL/FR
iso
phorone
FL
3,5,5-
trimethyl hexanol
FL/FR
herbal
hyssop oil
FL/FR
mentholic
cornmint oil terpeneless
FL/FR
dextro-neo
menthol
FL/FR
(±)-
menthol
FL/FR
peppermint cyclohexanone
FL/FR
minty
betula lenta bark oil america
FL/FR
1,8-
cineole
FL/FR
cornmint oil china
FL/FR
cornmint oil japan
FL/FR
limonene glycol
FL
homo
menthol
FL/FR
(±)-iso
menthone
FL/FR
(-)-
menthone
FL/FR
(±)-
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
myrtenal
FL/FR
myrtenol
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint oil idaho
FL/FR
iso
pulegol
FL/FR
(-)-iso
pulegol
FL/FR
spearmint oil america
FL/FR
WS-23
FL/FR
naphthyl
para-
methyl anisole
FL/FR
solvent
cyclohexyl acetate
FL/FR
sulfurous
mango thiol
FL/FR
woody
iso
bornyl formate
FL/FR
dehydroxylinalool oxide
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 chromelin (dimer)
2,5-dihydroxy-1,4-dioxane-2,5-dimethanol
2,5-dihydroxy-2,5-di(hydroxymethyl)-1,4-dioxane (dimer)
1,3-dihydroxyacetone dimer
2,5-dihydroxydioxane-2,5-dimethanol
1,4-dioxane-2,5-dimethanol, 2,5-dihydroxy-
(2S,5R)-2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol
2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol
 
 
Notes:
Used as a food additive [EAFUS]
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy