EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

2,4-dimethyl anisole
2,4-dimethylanisole

Sponsors

Name:1-methoxy-2,4-dimethylbenzene
CAS Number: 6738-23-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:229-794-9
FDA UNII:5V1B5L4GK6
Nikkaji Web:J149.887H
MDL:MFCD00008377
CoE Number:4063
XlogP3:3.10 (est)
Molecular Weight:136.19384000
Formula:C9 H12 O
NMR Predictor:Predict (works with chrome or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1245 2,4-dimethylanisole
FLAVIS Number:04.063 (Old)
DG SANTE Food Flavourings:04.063 1,3-dimethyl-4-methoxybenzene
FEMA Number:3828 2,4-dimethylanisole
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: 2,4-DIMETHYLANISOLE
 
Physical Properties:
Assay: 96.50 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.96300 to 0.96700 @ 25.00 °C.
Pounds per Gallon - (est).: 8.013 to 8.046
Refractive Index:1.51200 to 1.51600 @ 20.00 °C.
Boiling Point: 191.00 to 193.00 °C. @ 760.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.696000 mm/Hg @ 25.00 °C. (est)
Flash Point: 146.00 °F. TCC ( 63.33 °C. )
logP (o/w): 3.141 (est)
Soluble in:
 alcohol
 water, slightly
 water, 170.9 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: spicy
Odor Strength:medium ,
recommend smelling in a 1.00 % solution or less
spicy herbal
Odor Description:at 1.00 % in dipropylene glycol. spicy herbal
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
2,4-Dimethylanisole
Parchem
2,4-dimethyl anisole
Penta International
2,4-DIMETHYLANISOLE, Kosher
Santa Cruz Biotechnology
For experimental / research use only.
2,4-Dimethylanisole
Sigma-Aldrich: Aldrich
For experimental / research use only.
2,4-Dimethylanisole 97%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 [sex: M,F] > 2000 mg/kg
(Gilman, 1997)

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for 2,4-dimethyl anisole usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.12 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.20 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 18
 average usual ppmaverage maximum ppm
baked goods: 0.100000.20000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.100000.10000
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: 0.100000.10000
nut products: 0.100000.30000
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 0.100000.30000
soft candy: 0.100000.30000
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 23 (FGE.23): Aliphatic, alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (Commission Regulation (EC) No 1565/2000 of 18 July 2000
View page or View pdf

Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 23, Revision 1 (FGE.23Rev1): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010)
View page or View pdf

EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :81221
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-methoxy-2,4-dimethylbenzene
Chemidplus:0006738234
 
References:
 1-methoxy-2,4-dimethylbenzene
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):81221
Pubchem (sid):135037993
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):HMDB32149
FooDB:FDB008877
Export Tariff Code:2909.30.4000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
No odor group found for these
para-
menth-1-en-9-al
FL/FR
aldehydic
aldehydic
agrumen nitrile
FR
cheesy
2-
heptanone
FL/FR
earthy
3-
octen-2-one
FL/FR
floral
coriander seed oil
FL/FR
fruity
perillyl acetate
FL/FR
green
sec-
butyl-3-methyl but-2-ene thioate
FL/FR
carrot leaf oil (daucus carota ssp.maximus)
FR
privet dioxane
FR
herbal
carvacryl methyl ether
FL/FR
coriander seed absolute
FL/FR
coriander seed concrete
FR
herbal acetal
FR
1-para-
menthen-9-yl acetate
FL/FR
T-
muurolol
FL/FR
3-
nonanol
FL/FR
curled
parsley seed oil
FL/FR
saffron indenone
FL/FR
safranal
FL/FR
thymyl methyl ether
FL/FR
spicy
iso
butyl (E,E)-2,4-decadienamide
FL/FR
carrot weed oil
FL/FR
carvacryl ethyl ether
FL/FR
cinnamaldehyde dimethyl acetal
FL/FR
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
origanum majorana oil
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
woody
patchouli absolute
FR
For Flavor
No flavor group found for these
iso
butyl (E,E)-2,4-decadienamide
FL/FR
sec-
butyl-3-methyl but-2-ene thioate
FL/FR
carvacryl ethyl ether
FL/FR
carvacryl methyl ether
FL/FR
para-
menth-1-en-9-al
FL/FR
T-
muurolol
FL/FR
3-
nonanol
FL/FR
hexyl 3-mercaptobutanoate
FL
berry
berry
perillyl acetate
FL/FR
cheesy
2-
heptanone
FL/FR
creamy
3-
octen-2-one
FL/FR
fruity
1-para-
menthen-9-yl acetate
FL/FR
green
carrot weed oil
FL/FR
herbal
coriander seed absolute
FL/FR
coriander seed oil
FL/FR
origanum majorana oil
FL/FR
curled
parsley seed oil
FL/FR
saffron indenone
FL/FR
musty
thymyl methyl ether
FL/FR
spicy
cinnamaldehyde dimethyl acetal
FL/FR
(-)-
cubenol
FL/FR
cuminyl alcohol
FL/FR
black
currant bud absolute
FL/FR
origanum majorana oil cuba
FL/FR
origanum majorana oil morocco
FL/FR
woody
safranal
FL/FR
 
Potential Uses:
FRbalsam
FLherbal
FLspice
FRylang ylang
 
Occurrence (nature, food, other):note
 cheese mould ripened
Search PMC Picture
 marjoram wild marjoram
Search Trop Picture
 
Synonyms:
 benzene, 1-methoxy-2,4-dimethyl-
1,3-dimethyl-4-methoxybenzene
2,4-dimethylanisole
2,4-dimethylphenyl methyl ether
1-methoxy-2,4-dimethyl benzene
1-methoxy-2,4-dimethylbenzene
4-methoxy-m-xylene
 
 
Notes:
Food addiitive listed in the EAFUS Food Additive Database (Jan 2001). Found in camembert cheese. Food flavour
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy